482-38-2,MFCD21333499
Catalog No.:AA00DBHN

482-38-2 | Kaempferitrin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$82.00   $57.00
- +
5mg
≥98%
in stock  
$256.00   $179.00
- +
100mg
97%
in stock  
$472.00   $330.00
- +
250mg
97%
in stock  
$932.00   $653.00
- +
1g
97%
in stock  
$2,331.00 $1,632.00
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DBHN
Chemical Name:
Kaempferitrin
CAS Number:
482-38-2
Molecular Formula:
C27H30O14
Molecular Weight:
578.5187
MDL Number:
MFCD21333499
SMILES:
Oc1ccc(cc1)c1oc2cc(O[C@@H]3O[C@@H](C)[C@@H]([C@H]([C@H]3O)O)O)cc(c2c(=O)c1O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O
Properties
Computed Properties
 
Complexity:
968  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
8  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-0.1  

Upstream Synthesis Route

[1]TetrahedronLetters,2012,vol.53,#22,p.2773-2776

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

Downstream Synthesis Route

[1]Mohammed,HamdoonA.;AbdEl-Wahab,MohammedF.;Shaheen,Usama;Mohammed,AbdEl-SalamI.;Abdalla,AshrafN.;Ragab,EhabA.[Molecules,2021,vol.26,#19]

Literature

Title: Antidiabetic effects of Justicia spicigera Schltdl (Acanthaceae).

Journal: Journal of ethnopharmacology 20120928

Title: Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis.

Journal: Journal of natural products 20111128

Title: Effects of flavonoids on α-glucosidase activity: potential targets for glucose homeostasis.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20110101

Title: Changes in flavonoid content and tyrosinase inhibitory activity in kenaf leaf extract after far-infrared treatment.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.

Journal: Bioorganic & medicinal chemistry letters 20101215

Title: Identification of small molecule inhibitors of telomerase activity through transcriptional regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells.

Journal: Bioorganic & medicinal chemistry 20101001

Title: Studies on the chemical constituents from the stem and leaves of Tagetes erecta.

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100901

Title: Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes.

Journal: European journal of pharmacology 20090401

Title: Kaempferitrin inhibits GLUT4 translocation and glucose uptake in 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications 20090227

Title: A novel flavonoid from Lespedeza virgata (Thunb.) DC.: structural elucidation and antioxidative activity.

Journal: Bioorganic & medicinal chemistry letters 20071115

Title: Synthesis of kaempferitrin.

Journal: The Journal of organic chemistry 20070608

Title: Follow-up studies on glycosylated flavonoids and their complexes with vanadium: their anti-hyperglycemic potential role in diabetes.

Journal: Chemico-biological interactions 20061107

Title: Comparative assessment of kaempferitrin from medicinal extracts of Bauhinia forficata link.

Journal: Journal of pharmaceutical and biomedical analysis 20060503

Title: Determination of active components in Cynanchum chinense R. Br. by capillary electrophoresis.

Journal: Biomedical chromatography : BMC 20060501

Title: [The biotransformation of kaempferitrin by human intestinal flora].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20050801

Title: Insulinomimetic effects of kaempferitrin on glycaemia and on 14C-glucose uptake in rat soleus muscle.

Journal: Chemico-biological interactions 20041015

Title: Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves.

Journal: Journal of natural products 20040501

Title: [A case of acute renal failure after rifampicin use].

Journal: Klinicheskaia meditsina 19940101

Title: Tzeng YM, et al. Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes. Eur J Pharmacol. 2009 Apr 1;607(1-3):27-34.

Title: Alonso-Castro AJ, et al. Kaempferitrin induces apoptosis via intrinsic pathway in HeLa cells and exerts antitumor effects. J Ethnopharmacol. 2013 Jan 30;145(2):476-89.

Quotation Request
Company Name:
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Additional Info:
SDS
Tags:482-38-2 Molecular Formula|482-38-2 MDL|482-38-2 SMILES|482-38-2 Kaempferitrin
Catalog No.: AA00DBHN
482-38-2,MFCD21333499
482-38-2 | Kaempferitrin
Pack Size: 1mg
Purity: ≥98%
in stock
$82.00 $57.00
Pack Size: 5mg
Purity: ≥98%
in stock
$256.00 $179.00
Pack Size: 100mg
Purity: 97%
in stock
$472.00 $330.00
Pack Size: 250mg
Purity: 97%
in stock
$932.00 $653.00
Pack Size: 1g
Purity: 97%
in stock
$2,331.00 $1,632.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00DBHN
Chemical Name: Kaempferitrin
CAS Number: 482-38-2
Molecular Formula: C27H30O14
Molecular Weight: 578.5187
MDL Number: MFCD21333499
SMILES: Oc1ccc(cc1)c1oc2cc(O[C@@H]3O[C@@H](C)[C@@H]([C@H]([C@H]3O)O)O)cc(c2c(=O)c1O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O
Properties
Complexity: 968  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 10  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 41  
Hydrogen Bond Acceptor Count: 14  
Hydrogen Bond Donor Count: 8  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -0.1  
Upstream Synthesis Route
1374991-37-3    482-38-2 

[1]TetrahedronLetters,2012,vol.53,#22,p.2773-2776

943827-57-4    482-38-2 

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

943827-55-2    482-38-2 

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

943827-56-3    482-38-2 

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

943827-52-9    482-38-2 

[1]JournalofOrganicChemistry,2007,vol.72,#12,p.4582-4585

Downstream Synthesis Route
482-38-2    73-34-7    520-18-3 

[1]Mohammed,HamdoonA.;AbdEl-Wahab,MohammedF.;Shaheen,Usama;Mohammed,AbdEl-SalamI.;Abdalla,AshrafN.;Ragab,EhabA.[Molecules,2021,vol.26,#19]

Literature fold

Title: Antidiabetic effects of Justicia spicigera Schltdl (Acanthaceae).

Journal: Journal of ethnopharmacology20120928

Title: Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis.

Journal: Journal of natural products20111128

Title: Effects of flavonoids on α-glucosidase activity: potential targets for glucose homeostasis.

Journal: Nutrition (Burbank, Los Angeles County, Calif.)20110101

Title: Changes in flavonoid content and tyrosinase inhibitory activity in kenaf leaf extract after far-infrared treatment.

Journal: Bioorganic & medicinal chemistry letters20101215

Title: Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea.

Journal: Bioorganic & medicinal chemistry letters20101215

Title: Identification of small molecule inhibitors of telomerase activity through transcriptional regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells.

Journal: Bioorganic & medicinal chemistry20101001

Title: Studies on the chemical constituents from the stem and leaves of Tagetes erecta.

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100901

Title: Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes.

Journal: European journal of pharmacology20090401

Title: Kaempferitrin inhibits GLUT4 translocation and glucose uptake in 3T3-L1 adipocytes.

Journal: Biochemical and biophysical research communications20090227

Title: A novel flavonoid from Lespedeza virgata (Thunb.) DC.: structural elucidation and antioxidative activity.

Journal: Bioorganic & medicinal chemistry letters20071115

Title: Synthesis of kaempferitrin.

Journal: The Journal of organic chemistry20070608

Title: Follow-up studies on glycosylated flavonoids and their complexes with vanadium: their anti-hyperglycemic potential role in diabetes.

Journal: Chemico-biological interactions20061107

Title: Comparative assessment of kaempferitrin from medicinal extracts of Bauhinia forficata link.

Journal: Journal of pharmaceutical and biomedical analysis20060503

Title: Determination of active components in Cynanchum chinense R. Br. by capillary electrophoresis.

Journal: Biomedical chromatography : BMC20060501

Title: [The biotransformation of kaempferitrin by human intestinal flora].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20050801

Title: Insulinomimetic effects of kaempferitrin on glycaemia and on 14C-glucose uptake in rat soleus muscle.

Journal: Chemico-biological interactions20041015

Title: Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves.

Journal: Journal of natural products20040501

Title: [A case of acute renal failure after rifampicin use].

Journal: Klinicheskaia meditsina19940101

Title: Tzeng YM, et al. Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes. Eur J Pharmacol. 2009 Apr 1;607(1-3):27-34.

Title: Alonso-Castro AJ, et al. Kaempferitrin induces apoptosis via intrinsic pathway in HeLa cells and exerts antitumor effects. J Ethnopharmacol. 2013 Jan 30;145(2):476-89.

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