500-44-7,MFCD00075909
Catalog No.:AA00DEKQ

500-44-7 | L-MIMOSINE

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Purity
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25mg
≥98%
in stock  
$36.00   $25.00
- +
50mg
≥98%
in stock  
$55.00   $38.00
- +
100mg
≥98%
in stock  
$89.00   $62.00
- +
250mg
≥98%
in stock  
$200.00   $140.00
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1g
98+%
in stock  
$658.00   $461.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00DEKQ
Chemical Name:
L-MIMOSINE
CAS Number:
500-44-7
Molecular Formula:
C8H10N2O4
Molecular Weight:
198.1760
MDL Number:
MFCD00075909
SMILES:
OC(=O)[C@H](Cn1ccc(=O)c(c1)O)N
Properties
Computed Properties
 
Complexity:
321  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
-3.5  

Downstream Synthesis Route

[1]Bickel;Wibaut[RecueildesTravauxChimiquesdesPays-Bas,1946,vol.65,p.65,82]Wibaut[HelveticaChimicaActa,1946,vol.29,p.1669,1672]

500-44-7   
(S)-2,3-diaminopropionicacid 

[1]Beyerman,H.C.etal.[RecueildesTravauxChimiquesdesPays-Bas,1964,vol.83,p.1078-1082]

[1]Chemicalandpharmaceuticalbulletin,1986,vol.34,p.1473-1478

[2]Phytochemistry,1990,vol.29,p.2507-2508

[1]Murakoshi,Isamu;Ikegami,Fumio;Koide,Chiharu[Heterocycles,1984,vol.21,#2,p.705]

[1]Heterocycles,1984,vol.21,p.705

Literature

Title: Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.

Journal: Kidney international 20150401

Title: Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1α.

Journal: PloS one 20130101

Title: Productive performance and urinary excretion of mimosine metabolites by hair sheep grazing in a silvopastoral system with high densities of Leucaena leucocephala.

Journal: Tropical animal health and production 20121201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor in dental pulp-derived cells.

Journal: Journal of endodontics 20121101

Title: The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120801

Title: Preparative scale isolation, purification and derivatization of mimosine, a non-proteinogenic amino acid.

Journal: Amino acids 20120701

Title: A comparative study on mimosine, 3,4-dihydroxy pyridone (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP), purine derivatives (PD) excretion in the urine, thyroid hormone and blood metabolites profiles of Thai swamp buffalo (Bubalus bubalis) and Murrah buffalo (Bubalus bubalis).

Journal: Tropical animal health and production 20120401

Title: Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts.

Journal: Journal of periodontal research 20120401

Title: L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.

Journal: American journal of physiology. Cell physiology 20120215

Title: Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells.

Journal: Cell cycle (Georgetown, Tex.) 20120215

Title: Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation.

Journal: Neurochemical research 20120201

Title: Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine.

Journal: Nephrology (Carlton, Vic.) 20120101

Title: HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia.

Journal: PloS one 20120101

Title: Polyphenols: key issues involved in chemoprevention of prostate cancer.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase.

Journal: Journal of agricultural and food chemistry 20111228

Title: N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase.

Journal: Cancer letters 20111101

Title: Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.

Journal: Molecular nutrition & food research 20111101

Title: Upregulation of hypoxia-inducible factor 1 alpha in local vein wall is associated with enhanced venous thrombus resolution.

Journal: Thrombosis research 20111001

Title: Inhibitory effect of mimosine on polyphenoloxidase from cephalothoraxes of Pacific white shrimp (Litopenaeus vannamei).

Journal: Journal of agricultural and food chemistry 20110928

Title: Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics.

Journal: Rapid communications in mass spectrometry : RCM 20110915

Title: Pretreatment with intracoronary mimosine improves postischemic myocardial functional recovery.

Journal: Surgery 20110801

Title: Daboia russelli venom hyaluronidase: purification, characterization and inhibition by β-3-(3-hydroxy-4-oxopyridyl) α-amino-propionic Acid.

Journal: Current topics in medicinal chemistry 20110101

Title: Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B.

Journal: PloS one 20110101

Title: Tyrosinase inhibitory effect of benzoic acid derivatives and their structure-activity relationships.

Journal: Journal of enzyme inhibition and medicinal chemistry 20101201

Title: Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201

Title: Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20101201

Title: Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.

Journal: Antiviral research 20100601

Title: Xanthine oxidase/tyrosinase inhibiting, antioxidant, and antifungal oxindole alkaloids from Isatis costata.

Journal: Pharmaceutical biology 20100601

Title: Transgenic Leucaena leucocephala expressing the Rhizobium gene pydA encoding a meta-cleavage dioxygenase shows reduced mimosine content.

Journal: Plant physiology and biochemistry : PPB 20100401

Title: Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point.

Journal: BMC cell biology 20100101

Title: Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20091001

Title: Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283.

Journal: Cell cycle (Georgetown, Tex.) 20090615

Title: Association of luteinizing hormone receptor gene expression with cell cycle progression in granulosa cells.

Journal: American journal of physiology. Endocrinology and metabolism 20090601

Title: Coat condition of ringtailed lemurs, Lemur catta, at Berenty Reserve, Madagascar: II. Coat and tail alopecia associated with Leucaena leucocepahala, 2001-2006.

Journal: American journal of primatology 20090301

Title: Synthesis of 4-pyridone-3-sulfate and an improved synthesis of 3-hydroxy-4-pyridone.

Journal: Chemistry Central journal 20090101

Title: Pyruvate carboxylase is involved in metabolism of mimosine by Rhizobium sp. strain TAL1145.

Journal: Archives of microbiology 20081001

Title: The cloned 1-aminocyclopropane-1-carboxylate (ACC) deaminase gene from Sinorhizobium sp. strain BL3 in Rhizobium sp. strain TAL1145 promotes nodulation and growth of Leucaena leucocephala.

Journal: Systematic and applied microbiology 20080601

Title: Centrosome duplication proceeds during mimosine-induced G1 cell cycle arrest.

Journal: Journal of cellular physiology 20080401

Title: Kinetic properties of catecholoxidase activity of tarantula hemocyanin.

Journal: The FEBS journal 20080401

Title: S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining.

Journal: Oncogene 20080313

Title: In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.

Journal: Journal of medicinal chemistry 20080124

Title: Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes.

Journal: The Journal of infectious diseases 20080115

Title: A molecular mechanism for mimosine-induced apoptosis involving oxidative stress and mitochondrial activation.

Journal: Apoptosis : an international journal on programmed cell death 20080101

Title: Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury.

Journal: Journal of the American Society of Nephrology : JASN 20080101

Title: Kinetic properties of hexameric tyrosinase from the crustacean Palinurus elephas.

Journal: Photochemistry and photobiology 20080101

Title: Susceptibility of Autographa californica multiple nucleopolyhedrovirus to inhibitors of DNA replication.

Journal: Journal of virological methods 20071201

Title: Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum.

Journal: Phytotherapy research : PTR 20071101

Title: Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.

Journal: Journal of molecular histology 20071001

Title: Mimosine mitigates oxidative stress in selenium deficient seedlings of Vigna radiata. Part II: mitochondrial uptake of 75selenium and mimosine.

Journal: Biological trace element research 20070901

Title: Phytotoxic effects of 21 plant secondary metabolites on Arabidopsis thaliana germination and root growth.

Journal: Journal of chemical ecology 20070701

Title: Mimosine mitigates oxidative stress in selenium deficient seedlings of Vigna radiata--Part I: Restoration of mitochondrial function.

Journal: Biological trace element research 20070701

Title: The pydA-pydB fusion gene produces an active dioxygenase-hydrolase that degrades 3-hydroxy-4-pyridone, an intermediate of mimosine metabolism.

Journal: Applied microbiology and biotechnology 20070601

Title: Prediction of tyrosinase inhibition activity using atom-based bilinear indices.

Journal: ChemMedChem 20070401

Title: Studies on cell-cycle synchronization in the asexual erythrocytic stages of Plasmodium falciparum.

Journal: Parasitology 20070301

Title: TOMOCOMD-CARDD descriptors-based virtual screening of tyrosinase inhibitors: evaluation of different classification model combinations using bond-based linear indices.

Journal: Bioorganic & medicinal chemistry 20070201

Title: Determination of growth inhibitory action point of interferon gamma on WISH cells in cell cycle progression and the window of responsiveness of the cells to the interferon.

Journal: Cytokine 20070201

Title: The mitotic manipulation of cytotrophoblast differentiation in vitro.

Journal: Placenta 20070101

Title: Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys.

Journal: American journal of physiology. Renal physiology 20070101

Title: Dragon method for finding novel tyrosinase inhibitors: Biosilico identification and experimental in vitro assays.

Journal: European journal of medicinal chemistry 20070101

Title: Plant secondary metabolites.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Selective determination of mimosine and its dihydroxypyridinyl derivative in plant systems.

Journal: Amino acids 20061001

Title: Tyrosinase inhibition studies of cycloartane and cucurbitane glycosides and their structure-activity relationships.

Journal: Bioorganic & medicinal chemistry 20060901

Title: Oxazolones: new tyrosinase inhibitors; synthesis and their structure-activity relationships.

Journal: Bioorganic & medicinal chemistry 20060901

Title: G1/S phase synchronization using mimosine arrest.

Journal: CSH protocols 20060901

Title: Piperidones with activity against Plasmodium falciparum.

Journal: Parasitology research 20060801

Title: Distinctive activities of DNA polymerases during human DNA replication.

Journal: The FEBS journal 20060701

Title: Newt orthologue of Growth arrest-specific 6 (NvGas6) is implicated in stress response during newt forelimb regeneration.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20060301

Title: Tyrosinase inhibitory cycloartane type triterpenoids from the methanol extract of the whole plant of Amberboa ramosa Jafri and their structure-activity relationship.

Journal: Bioorganic & medicinal chemistry 20060215

Title: Tetraketones: a new class of tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry 20060115

Title: Antidermatophytic and bacterial activity of mimosine.

Journal: Phytotherapy research : PTR 20051101

Title: Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells.

Journal: European journal of pharmacology 20051017

Title: Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts.

Journal: Molecular & cellular proteomics : MCP 20050901

Title: Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis.

Journal: Molecular & cellular proteomics : MCP 20050701

Title: Tyrosinase inhibition studies of diterpenoid alkaloids and their derivatives: structure-activity relationships.

Journal: Natural product research 20050701

Title: Structure-activity relationships of tyrosinase inhibitory combinatorial library of 2,5-disubstituted-1,3,4-oxadiazole analogues.

Journal: Bioorganic & medicinal chemistry 20050516

Title: Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells.

Journal: Journal of neurochemistry 20050501

Title: Synthesis of methyl ether analogues of sildenafil (Viagra) possessing tyrosinase inhibitory potential.

Journal: Chemistry & biodiversity 20050401

Title: Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.

Journal: The Journal of biological chemistry 20050128

Title: Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication.

Journal: The Journal of biological chemistry 20050107

Title: Inhibition of MCP-1 and MIP-2 chemokines in murine trichinellosis: effect of the anti-inflammatory compound L-mimosine.

Journal: International journal of immunopathology and pharmacology 20050101

Title: P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosine.

Journal: Pathology oncology research : POR 20050101

Title: Tyrosinase inhibitors from Rhododendron collettianum and their structure-activity relationship (SAR) studies.

Journal: Chemical & pharmaceutical bulletin 20041201

Title: Cell cycle arrest at the initiation step of human chromosomal DNA replication causes DNA damage.

Journal: Journal of cell science 20041001

Title: Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation.

Journal: Oncogene 20040701

Title: Slow-binding inhibition: A theoretical and practical course for students.

Journal: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20040701

Title: Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth.

Journal: Oncogene 20040506

Title: AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression.

Journal: The Journal of biological chemistry 20040409

Title: Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis.

Journal: American journal of physiology. Cell physiology 20040201

Title: PPARgamma1 synthesis and adipogenesis in C3H10T1/2 cells depends on S-phase progression, but does not require mitotic clonal expansion.

Journal: Journal of cellular biochemistry 20040201

Title: p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells.

Journal: Cell death and differentiation 20040101

Title: Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines.

Journal: Anticancer research 20040101

Title: Response of ADA and its isoenzymes in mice infected by Trichinella spiralis and treated with mimosine.

Journal: International journal of immunopathology and pharmacology 20040101

Title: Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells.

Journal: American journal of human genetics 20031101

Title: Potential therapeutic applications of some antinutritional plant secondary metabolites.

Journal: Journal of agricultural and food chemistry 20030910

Title: Cell cycle synchronization of porcine granulosa cells in G1 stage with mimosine.

Journal: Animal reproduction science 20030715

Title: Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601

Title: Cell cycle inhibition mediated by the outer surface of the C/EBPalpha basic region is required but not sufficient for granulopoiesis.

Journal: Oncogene 20030501

Title: Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.

Journal: Molecular cancer research : MCR 20030501

Title: Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.

Journal: Genes & development 20030315

Title: Truffle thio-flavours reversibly inhibit truffle tyrosinase.

Journal: FEMS microbiology letters 20030314

Title: Spectroscopic characterization of the electronic changes in the active site of Streptomyces antibioticus tyrosinase upon binding of transition state analogue inhibitors.

Journal: The Journal of biological chemistry 20030227

Title: The mid genes of Rhizobium sp strain TAL1145 are required for degradation of mimosine into 3-hydroxy-4-pyridone and are inducible by mimosine.

Journal: Microbiology (Reading, England) 20030201

Title: Effect of the compound L-mimosine in an in vivo model of chronic granuloma formation induced by potassium permanganate (KMNO4).

Journal: International journal of immunopathology and pharmacology 20030101

Title: DNA breaks induction by mimosine.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

Title: Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenografts.

Journal: Anticancer research 20030101

Title: Enantioseparation of chiral aromatic amino acids by capillary electrophoresis in neutral and charged cyclodextrin selector modes.

Journal: Electrophoresis 20021201

Title: Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts.

Journal: DNA repair 20021001

Title: Engineering bacterial competitiveness and persistence in the phytosphere.

Journal: Molecular plant-microbe interactions : MPMI 20020901

Title: Association between the cell cycle and neural crest delamination through specific regulation of G1/S transition.

Journal: Developmental cell 20020901

Title: Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs.

Journal: Biochemical and biophysical research communications 20020823

Title: Mimosine prevents the death of glucose-deprived immunostimulated astrocytes by scavenging peroxynitrite.

Journal: Glia 20020701

Title: Inhibition of ultraviolet B (UVB) induced apoptosis in A431 cells by mimosine is not dependent on cell cycle arrest.

Journal: Canadian journal of physiology and pharmacology 20020701

Title: A novel association of the SMN protein with two major non-ribosomal nucleolar proteins and its implication in spinal muscular atrophy.

Journal: Human molecular genetics 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors.

Journal: Biochimica et biophysica acta 20020213

Title: Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.

Journal: Journal of cell science 20020201

Title: Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Journal: Oncogene 20020117

Title: Inhibition of MCP-1 and MIP-2 transcription and translation by mimosine in muscle tissue infected with the parasite Trichinella spiralis.

Journal: Molecular and cellular biochemistry 20020101

Title: The deoxyribo-mode expression of primase activities of the primase-alpha DNA polymerase enzyme complex associated with nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate.

Journal: Acta virologica 20020101

Title: Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.

Journal: Chromosoma 20011201

Title: Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector.

Journal: Biomolecular engineering 20011031

Title: A DNA polymerase epsilon inhibitor activates the ribo and deoxyribo modes of primase expression and induces a unique phenomenon of primer accumulation.

Journal: FEBS letters 20010907

Title: Characterization of homologous recombination induced by replication inhibition in mammalian cells.

Journal: The EMBO journal 20010716

Title: Selection of several classes of mimosine-degradation-defective Tn3Hogus-insertion mutants of Rhizobium sp. strain TAL1145 on the basis of mimosine-inducible GUS activity.

Journal: Canadian journal of microbiology 20010601

Title: Methods for synchronizing cells at specific stages of the cell cycle.

Journal: Current protocols in cell biology 20010501

Title: Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.

Journal: Journal of cellular physiology 20010401

Title: Anatomy of the primase-alpha DNA polymerase reaction accomplished by nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate.

Journal: Acta virologica 20010401

Title: Kinetic analyses of mitochondrial 75selenium uptake in Trigonella foenum-graecum seedlings exposed to selenium and mimosine.

Journal: Biological trace element research 20010301

Title: MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3.

Journal: EMBO reports 20010215

Title: Radiation sensitization of mammalian cells by metal chelators.

Journal: Radiation research 20010201

Title: Prevention of entrance into G2 cell cycle phase by mimosine decreases locomotion of cells from the tumor cell line SW480.

Journal: Cancer letters 20010101

Title: Uptake of 45Ca by mitochondria of Trigonella foenum-graecum as influenced by selenium and mimosine--detailed kinetic analyses.

Journal: Biological trace element research 20010101

Title: Modulation of cell cycle regulatory protein expression and suppression of tumor growth by mimosine in nude mice.

Journal: International journal of oncology 20001001

Title: Steroid hormone activity of flavonoids and related compounds.

Journal: Breast cancer research and treatment 20000701

Title: Mimosine arrests cells in G1 by enhancing the levels of p27(Kip1).

Journal: Experimental cell research 20000110

Title: Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 19991115

Title: Inhibitory effect of mimosine on proliferation of human lung cancer cells is mediated by multiple mechanisms.

Journal: Cancer letters 19991018

Title: Antiretroviral effects of deoxyhypusyl hydroxylase inhibitors: a hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1).

Journal: Biochemical pharmacology 19980601

Title: Submicromolar paclitaxel induces apoptosis in human gastric cancer cells at early G1 phase.

Journal: Anticancer research 19980101

Title: The effect of administration of glycine and tyrosine on the growth depression caused by mimosine in rats.

Journal: Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde 19830801

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Tags:500-44-7 Molecular Formula|500-44-7 MDL|500-44-7 SMILES|500-44-7 L-MIMOSINE
Catalog No.: AA00DEKQ
500-44-7,MFCD00075909
500-44-7 | L-MIMOSINE
Pack Size: 25mg
Purity: ≥98%
in stock
$36.00 $25.00
Pack Size: 50mg
Purity: ≥98%
in stock
$55.00 $38.00
Pack Size: 100mg
Purity: ≥98%
in stock
$89.00 $62.00
Pack Size: 250mg
Purity: ≥98%
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$200.00 $140.00
Pack Size: 1g
Purity: 98+%
in stock
$658.00 $461.00
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Technical Information
Catalog Number: AA00DEKQ
Chemical Name: L-MIMOSINE
CAS Number: 500-44-7
Molecular Formula: C8H10N2O4
Molecular Weight: 198.1760
MDL Number: MFCD00075909
SMILES: OC(=O)[C@H](Cn1ccc(=O)c(c1)O)N
Properties
Complexity: 321  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 14  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 3  
XLogP3: -3.5  
Downstream Synthesis Route
77-78-1    500-44-7    50700-62-4 

[1]Bickel;Wibaut[RecueildesTravauxChimiquesdesPays-Bas,1946,vol.65,p.65,82]Wibaut[HelveticaChimicaActa,1946,vol.29,p.1669,1672]

500-44-7   
(S)-2,3-diaminopropionicacid 

[1]Beyerman,H.C.etal.[RecueildesTravauxChimiquesdesPays-Bas,1964,vol.83,p.1078-1082]

10182-48-6    5147-00-2    500-44-7 

[1]Chemicalandpharmaceuticalbulletin,1986,vol.34,p.1473-1478

[2]Phytochemistry,1990,vol.29,p.2507-2508

1121-23-9    56-45-1    500-44-7 

[1]Murakoshi,Isamu;Ikegami,Fumio;Koide,Chiharu[Heterocycles,1984,vol.21,#2,p.705]

1121-23-9    5147-00-2    500-44-7 

[1]Heterocycles,1984,vol.21,p.705

Literature fold

Title: Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.

Journal: Kidney international20150401

Title: Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1α.

Journal: PloS one20130101

Title: Productive performance and urinary excretion of mimosine metabolites by hair sheep grazing in a silvopastoral system with high densities of Leucaena leucocephala.

Journal: Tropical animal health and production20121201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry20121115

Title: Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor in dental pulp-derived cells.

Journal: Journal of endodontics20121101

Title: The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20120801

Title: Preparative scale isolation, purification and derivatization of mimosine, a non-proteinogenic amino acid.

Journal: Amino acids20120701

Title: A comparative study on mimosine, 3,4-dihydroxy pyridone (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP), purine derivatives (PD) excretion in the urine, thyroid hormone and blood metabolites profiles of Thai swamp buffalo (Bubalus bubalis) and Murrah buffalo (Bubalus bubalis).

Journal: Tropical animal health and production20120401

Title: Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts.

Journal: Journal of periodontal research20120401

Title: L-Mimosine blocks cell proliferation via upregulation of B-cell translocation gene 2 and N-myc downstream regulated gene 1 in prostate carcinoma cells.

Journal: American journal of physiology. Cell physiology20120215

Title: Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells.

Journal: Cell cycle (Georgetown, Tex.)20120215

Title: Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation.

Journal: Neurochemical research20120201

Title: Transient hypoxia-inducible factor activation in rat renal ablation and reduced fibrosis with L-mimosine.

Journal: Nephrology (Carlton, Vic.)20120101

Title: HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia.

Journal: PloS one20120101

Title: Polyphenols: key issues involved in chemoprevention of prostate cancer.

Journal: Oxidative medicine and cellular longevity20120101

Title: Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase.

Journal: Journal of agricultural and food chemistry20111228

Title: N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase.

Journal: Cancer letters20111101

Title: Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.

Journal: Molecular nutrition & food research20111101

Title: Upregulation of hypoxia-inducible factor 1 alpha in local vein wall is associated with enhanced venous thrombus resolution.

Journal: Thrombosis research20111001

Title: Inhibitory effect of mimosine on polyphenoloxidase from cephalothoraxes of Pacific white shrimp (Litopenaeus vannamei).

Journal: Journal of agricultural and food chemistry20110928

Title: Formation of dehydroalanine from mimosine and cysteine: artifacts in gas chromatography/mass spectrometry based metabolomics.

Journal: Rapid communications in mass spectrometry : RCM20110915

Title: Pretreatment with intracoronary mimosine improves postischemic myocardial functional recovery.

Journal: Surgery20110801

Title: Daboia russelli venom hyaluronidase: purification, characterization and inhibition by β-3-(3-hydroxy-4-oxopyridyl) α-amino-propionic Acid.

Journal: Current topics in medicinal chemistry20110101

Title: Phosphorylation of AIB1 at mitosis is regulated by CDK1/CYCLIN B.

Journal: PloS one20110101

Title: Tyrosinase inhibitory effect of benzoic acid derivatives and their structure-activity relationships.

Journal: Journal of enzyme inhibition and medicinal chemistry20101201

Title: Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20101201

Title: Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization.

Journal: Arteriosclerosis, thrombosis, and vascular biology20101201

Title: Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.

Journal: Antiviral research20100601

Title: Xanthine oxidase/tyrosinase inhibiting, antioxidant, and antifungal oxindole alkaloids from Isatis costata.

Journal: Pharmaceutical biology20100601

Title: Transgenic Leucaena leucocephala expressing the Rhizobium gene pydA encoding a meta-cleavage dioxygenase shows reduced mimosine content.

Journal: Plant physiology and biochemistry : PPB20100401

Title: Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point.

Journal: BMC cell biology20100101

Title: Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20091001

Title: Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283.

Journal: Cell cycle (Georgetown, Tex.)20090615

Title: Association of luteinizing hormone receptor gene expression with cell cycle progression in granulosa cells.

Journal: American journal of physiology. Endocrinology and metabolism20090601

Title: Coat condition of ringtailed lemurs, Lemur catta, at Berenty Reserve, Madagascar: II. Coat and tail alopecia associated with Leucaena leucocepahala, 2001-2006.

Journal: American journal of primatology20090301

Title: Synthesis of 4-pyridone-3-sulfate and an improved synthesis of 3-hydroxy-4-pyridone.

Journal: Chemistry Central journal20090101

Title: Pyruvate carboxylase is involved in metabolism of mimosine by Rhizobium sp. strain TAL1145.

Journal: Archives of microbiology20081001

Title: The cloned 1-aminocyclopropane-1-carboxylate (ACC) deaminase gene from Sinorhizobium sp. strain BL3 in Rhizobium sp. strain TAL1145 promotes nodulation and growth of Leucaena leucocephala.

Journal: Systematic and applied microbiology20080601

Title: Centrosome duplication proceeds during mimosine-induced G1 cell cycle arrest.

Journal: Journal of cellular physiology20080401

Title: Kinetic properties of catecholoxidase activity of tarantula hemocyanin.

Journal: The FEBS journal20080401

Title: S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining.

Journal: Oncogene20080313

Title: In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.

Journal: Journal of medicinal chemistry20080124

Title: Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes.

Journal: The Journal of infectious diseases20080115

Title: A molecular mechanism for mimosine-induced apoptosis involving oxidative stress and mitochondrial activation.

Journal: Apoptosis : an international journal on programmed cell death20080101

Title: Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury.

Journal: Journal of the American Society of Nephrology : JASN20080101

Title: Kinetic properties of hexameric tyrosinase from the crustacean Palinurus elephas.

Journal: Photochemistry and photobiology20080101

Title: Susceptibility of Autographa californica multiple nucleopolyhedrovirus to inhibitors of DNA replication.

Journal: Journal of virological methods20071201

Title: Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum.

Journal: Phytotherapy research : PTR20071101

Title: Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.

Journal: Journal of molecular histology20071001

Title: Mimosine mitigates oxidative stress in selenium deficient seedlings of Vigna radiata. Part II: mitochondrial uptake of 75selenium and mimosine.

Journal: Biological trace element research20070901

Title: Phytotoxic effects of 21 plant secondary metabolites on Arabidopsis thaliana germination and root growth.

Journal: Journal of chemical ecology20070701

Title: Mimosine mitigates oxidative stress in selenium deficient seedlings of Vigna radiata--Part I: Restoration of mitochondrial function.

Journal: Biological trace element research20070701

Title: The pydA-pydB fusion gene produces an active dioxygenase-hydrolase that degrades 3-hydroxy-4-pyridone, an intermediate of mimosine metabolism.

Journal: Applied microbiology and biotechnology20070601

Title: Prediction of tyrosinase inhibition activity using atom-based bilinear indices.

Journal: ChemMedChem20070401

Title: Studies on cell-cycle synchronization in the asexual erythrocytic stages of Plasmodium falciparum.

Journal: Parasitology20070301

Title: TOMOCOMD-CARDD descriptors-based virtual screening of tyrosinase inhibitors: evaluation of different classification model combinations using bond-based linear indices.

Journal: Bioorganic & medicinal chemistry20070201

Title: Determination of growth inhibitory action point of interferon gamma on WISH cells in cell cycle progression and the window of responsiveness of the cells to the interferon.

Journal: Cytokine20070201

Title: The mitotic manipulation of cytotrophoblast differentiation in vitro.

Journal: Placenta20070101

Title: Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys.

Journal: American journal of physiology. Renal physiology20070101

Title: Dragon method for finding novel tyrosinase inhibitors: Biosilico identification and experimental in vitro assays.

Journal: European journal of medicinal chemistry20070101

Title: Plant secondary metabolites.

Journal: Methods in molecular biology (Clifton, N.J.)20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling20061101

Title: Selective determination of mimosine and its dihydroxypyridinyl derivative in plant systems.

Journal: Amino acids20061001

Title: Tyrosinase inhibition studies of cycloartane and cucurbitane glycosides and their structure-activity relationships.

Journal: Bioorganic & medicinal chemistry20060901

Title: Oxazolones: new tyrosinase inhibitors; synthesis and their structure-activity relationships.

Journal: Bioorganic & medicinal chemistry20060901

Title: G1/S phase synchronization using mimosine arrest.

Journal: CSH protocols20060901

Title: Piperidones with activity against Plasmodium falciparum.

Journal: Parasitology research20060801

Title: Distinctive activities of DNA polymerases during human DNA replication.

Journal: The FEBS journal20060701

Title: Newt orthologue of Growth arrest-specific 6 (NvGas6) is implicated in stress response during newt forelimb regeneration.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists20060301

Title: Tyrosinase inhibitory cycloartane type triterpenoids from the methanol extract of the whole plant of Amberboa ramosa Jafri and their structure-activity relationship.

Journal: Bioorganic & medicinal chemistry20060215

Title: Tetraketones: a new class of tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry20060115

Title: Antidermatophytic and bacterial activity of mimosine.

Journal: Phytotherapy research : PTR20051101

Title: Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells.

Journal: European journal of pharmacology20051017

Title: Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts.

Journal: Molecular & cellular proteomics : MCP20050901

Title: Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis.

Journal: Molecular & cellular proteomics : MCP20050701

Title: Tyrosinase inhibition studies of diterpenoid alkaloids and their derivatives: structure-activity relationships.

Journal: Natural product research20050701

Title: Structure-activity relationships of tyrosinase inhibitory combinatorial library of 2,5-disubstituted-1,3,4-oxadiazole analogues.

Journal: Bioorganic & medicinal chemistry20050516

Title: Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells.

Journal: Journal of neurochemistry20050501

Title: Synthesis of methyl ether analogues of sildenafil (Viagra) possessing tyrosinase inhibitory potential.

Journal: Chemistry & biodiversity20050401

Title: Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation.

Journal: The Journal of biological chemistry20050128

Title: Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication.

Journal: The Journal of biological chemistry20050107

Title: Inhibition of MCP-1 and MIP-2 chemokines in murine trichinellosis: effect of the anti-inflammatory compound L-mimosine.

Journal: International journal of immunopathology and pharmacology20050101

Title: P-glycoprotein expression is induced in human pancreatic cancer xenografts during treatment with a cell cycle regulator, mimosine.

Journal: Pathology oncology research : POR20050101

Title: Tyrosinase inhibitors from Rhododendron collettianum and their structure-activity relationship (SAR) studies.

Journal: Chemical & pharmaceutical bulletin20041201

Title: Cell cycle arrest at the initiation step of human chromosomal DNA replication causes DNA damage.

Journal: Journal of cell science20041001

Title: Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation.

Journal: Oncogene20040701

Title: Slow-binding inhibition: A theoretical and practical course for students.

Journal: Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology20040701

Title: Role of eIF3 p170 in controlling synthesis of ribonucleotide reductase M2 and cell growth.

Journal: Oncogene20040506

Title: AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression.

Journal: The Journal of biological chemistry20040409

Title: Rb regulates C/EBPbeta-DNA-binding activity during 3T3-L1 adipogenesis.

Journal: American journal of physiology. Cell physiology20040201

Title: PPARgamma1 synthesis and adipogenesis in C3H10T1/2 cells depends on S-phase progression, but does not require mitotic clonal expansion.

Journal: Journal of cellular biochemistry20040201

Title: p53-independent induction of p21(waf1/cip1) contributes to the activation of caspases in GTP-depletion-induced apoptosis of insulin-secreting cells.

Journal: Cell death and differentiation20040101

Title: Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines.

Journal: Anticancer research20040101

Title: Response of ADA and its isoenzymes in mice infected by Trichinella spiralis and treated with mimosine.

Journal: International journal of immunopathology and pharmacology20040101

Title: Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells.

Journal: American journal of human genetics20031101

Title: Potential therapeutic applications of some antinutritional plant secondary metabolites.

Journal: Journal of agricultural and food chemistry20030910

Title: Cell cycle synchronization of porcine granulosa cells in G1 stage with mimosine.

Journal: Animal reproduction science20030715

Title: Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20030601

Title: Cell cycle inhibition mediated by the outer surface of the C/EBPalpha basic region is required but not sufficient for granulopoiesis.

Journal: Oncogene20030501

Title: Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes.

Journal: Molecular cancer research : MCR20030501

Title: Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.

Journal: Genes & development20030315

Title: Truffle thio-flavours reversibly inhibit truffle tyrosinase.

Journal: FEMS microbiology letters20030314

Title: Spectroscopic characterization of the electronic changes in the active site of Streptomyces antibioticus tyrosinase upon binding of transition state analogue inhibitors.

Journal: The Journal of biological chemistry20030227

Title: The mid genes of Rhizobium sp strain TAL1145 are required for degradation of mimosine into 3-hydroxy-4-pyridone and are inducible by mimosine.

Journal: Microbiology (Reading, England)20030201

Title: Effect of the compound L-mimosine in an in vivo model of chronic granuloma formation induced by potassium permanganate (KMNO4).

Journal: International journal of immunopathology and pharmacology20030101

Title: DNA breaks induction by mimosine.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences20030101

Title: Mimosine, a plant-derived amino acid induces apoptosis in human pancreatic cancer xenografts.

Journal: Anticancer research20030101

Title: Enantioseparation of chiral aromatic amino acids by capillary electrophoresis in neutral and charged cyclodextrin selector modes.

Journal: Electrophoresis20021201

Title: Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts.

Journal: DNA repair20021001

Title: Engineering bacterial competitiveness and persistence in the phytosphere.

Journal: Molecular plant-microbe interactions : MPMI20020901

Title: Association between the cell cycle and neural crest delamination through specific regulation of G1/S transition.

Journal: Developmental cell20020901

Title: Cell-cycle-dependent regulation of CNT1, a concentrative nucleoside transporter involved in the uptake of cell-cycle-dependent nucleoside-derived anticancer drugs.

Journal: Biochemical and biophysical research communications20020823

Title: Mimosine prevents the death of glucose-deprived immunostimulated astrocytes by scavenging peroxynitrite.

Journal: Glia20020701

Title: Inhibition of ultraviolet B (UVB) induced apoptosis in A431 cells by mimosine is not dependent on cell cycle arrest.

Journal: Canadian journal of physiology and pharmacology20020701

Title: A novel association of the SMN protein with two major non-ribosomal nucleolar proteins and its implication in spinal muscular atrophy.

Journal: Human molecular genetics20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors.

Journal: Biochimica et biophysica acta20020213

Title: Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function.

Journal: Journal of cell science20020201

Title: Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Journal: Oncogene20020117

Title: Inhibition of MCP-1 and MIP-2 transcription and translation by mimosine in muscle tissue infected with the parasite Trichinella spiralis.

Journal: Molecular and cellular biochemistry20020101

Title: The deoxyribo-mode expression of primase activities of the primase-alpha DNA polymerase enzyme complex associated with nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate.

Journal: Acta virologica20020101

Title: Lymphoblasts already in the DNA synthesis phase of the cell cycle can be reversibly arrested at the R/G transition.

Journal: Chromosoma20011201

Title: Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector.

Journal: Biomolecular engineering20011031

Title: A DNA polymerase epsilon inhibitor activates the ribo and deoxyribo modes of primase expression and induces a unique phenomenon of primer accumulation.

Journal: FEBS letters20010907

Title: Characterization of homologous recombination induced by replication inhibition in mammalian cells.

Journal: The EMBO journal20010716

Title: Selection of several classes of mimosine-degradation-defective Tn3Hogus-insertion mutants of Rhizobium sp. strain TAL1145 on the basis of mimosine-inducible GUS activity.

Journal: Canadian journal of microbiology20010601

Title: Methods for synchronizing cells at specific stages of the cell cycle.

Journal: Current protocols in cell biology20010501

Title: Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.

Journal: Journal of cellular physiology20010401

Title: Anatomy of the primase-alpha DNA polymerase reaction accomplished by nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl deoxyguanosine-5'-triphosphate.

Journal: Acta virologica20010401

Title: Kinetic analyses of mitochondrial 75selenium uptake in Trigonella foenum-graecum seedlings exposed to selenium and mimosine.

Journal: Biological trace element research20010301

Title: MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3.

Journal: EMBO reports20010215

Title: Radiation sensitization of mammalian cells by metal chelators.

Journal: Radiation research20010201

Title: Prevention of entrance into G2 cell cycle phase by mimosine decreases locomotion of cells from the tumor cell line SW480.

Journal: Cancer letters20010101

Title: Uptake of 45Ca by mitochondria of Trigonella foenum-graecum as influenced by selenium and mimosine--detailed kinetic analyses.

Journal: Biological trace element research20010101

Title: Modulation of cell cycle regulatory protein expression and suppression of tumor growth by mimosine in nude mice.

Journal: International journal of oncology20001001

Title: Steroid hormone activity of flavonoids and related compounds.

Journal: Breast cancer research and treatment20000701

Title: Mimosine arrests cells in G1 by enhancing the levels of p27(Kip1).

Journal: Experimental cell research20000110

Title: Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience19991115

Title: Inhibitory effect of mimosine on proliferation of human lung cancer cells is mediated by multiple mechanisms.

Journal: Cancer letters19991018

Title: Antiretroviral effects of deoxyhypusyl hydroxylase inhibitors: a hypusine-dependent host cell mechanism for replication of human immunodeficiency virus type 1 (HIV-1).

Journal: Biochemical pharmacology19980601

Title: Submicromolar paclitaxel induces apoptosis in human gastric cancer cells at early G1 phase.

Journal: Anticancer research19980101

Title: The effect of administration of glycine and tyrosine on the growth depression caused by mimosine in rats.

Journal: Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde19830801

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