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5793-89-5,MFCD00043409
Catalog No.:AA00E8XQ

5793-89-5 | Calcium (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate tetrahydrate

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Purity
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25g
≥95%
in stock  
$55.00   $38.00
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50g
≥95%
in stock  
$102.00   $71.00
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100g
≥95%
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$169.00   $118.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00E8XQ
Chemical Name:
Calcium (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate tetrahydrate
CAS Number:
5793-89-5
Molecular Formula:
C6H16CaO12
Molecular Weight:
320.2620
MDL Number:
MFCD00043409
SMILES:
O[C@H]([C@H](C(=O)[O-])O)[C@@H]([C@@H](C(=O)[O-])O)O.[Ca+2].O.O.O.O
Properties
Properties
 
Form:
Solid  
MP:
>185ºC (dec.)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
191  
Covalently-Bonded Unit Count:
6  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
3  

Literature

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Journal: Chemico-biological interactions 20150125

Title: Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice.

Journal: International journal of oncology 20130901

Title: A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut.

Journal: Molecular pharmaceutics 20121105

Title: Is [(99m)Tc]glucarate uptake mediated by fructose transporter GLUT-5?

Journal: Nuclear medicine and biology 20121101

Title: Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets.

Journal: The Journal of endocrinology 20120901

Title: Changing patterns of anemia management in US hemodialysis patients.

Journal: The American journal of medicine 20120901

Title: [Multi-frequency low-dose intravenous iron on oxidative stress in maintenance hemodialysis patients].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120801

Title: Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance.

Journal: The Journal of biological chemistry 20120629

Title: Detection of myocardial ischemia-reperfusion injury using a fluorescent near-infrared zinc(II)-dipicolylamine probe and 99mTc glucarate.

Journal: Molecular imaging 20120601

Title: Computer simulations of osmotic ultrafiltration and small-solute transport in peritoneal dialysis: a spatially distributed approach.

Journal: American journal of physiology. Renal physiology 20120515

Title: Intravenous iron treatment in pregnancy: comparison of high-dose ferric carboxymaltose vs. iron sucrose.

Journal: Journal of perinatal medicine 20120513

Title: Safety and efficacy of high-dose intravenous iron carboxymaltose vs. iron sucrose for treatment of postpartum anemia.

Journal: Journal of perinatal medicine 20120402

Title: Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis.

Journal: Journal of hepatology 20120301

Title: Modulation of Pseudomonas aeruginosa lipopolysaccharide-induced lung inflammation by chronic iron overload in rat.

Journal: FEMS immunology and medical microbiology 20120301

Title: Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway.

Journal: Free radical research 20120301

Title: Modifications in the nitric acid oxidation of D-glucose.

Journal: Carbohydrate research 20120301

Title: Clinical case reports raise doubts about the therapeutic equivalence of an iron sucrose similar preparation compared with iron sucrose originator.

Journal: Current medical research and opinion 20120201

Title: Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance.

Journal: Endocrinology 20120201

Title: Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration.

Journal: American journal of nephrology 20120201

Title: Comparison of oxidative stress and inflammation induced by different intravenous iron sucrose similar preparations in a rat model.

Journal: Inflammation & allergy drug targets 20120201

Title: The effect of different doses and types of intravenous iron on oxidative stress and inflammation in hemodialysis patients.

Journal: Journal of nephrology 20120101

Title: Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation.

Journal: PloS one 20120101

Title: Iron sucrose impairs phagocytic function and promotes apoptosis in polymorphonuclear leukocytes.

Journal: American journal of nephrology 20120101

Title: Methamphetamine causes anorexia in Drosophila melanogaster, exhausting metabolic reserves and contributing to mortality.

Journal: The Journal of toxicological sciences 20120101

Title: D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway.

Journal: Toxicology and applied pharmacology 20111201

Title: Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed?

Journal: Molecular nutrition & food research 20111201

Title: Characterization of D-glucaric acid using NMR, X-ray crystal structure, and MM3 molecular modeling analyses.

Journal: Carbohydrate research 20111129

Title: Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults.

Journal: Nutrition research (New York, N.Y.) 20111101

Title: Do two intravenous iron sucrose preparations have the same efficacy?

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001

Title: Intravenous iron for the treatment of fatigue in nonanemic, premenopausal women with low serum ferritin concentration.

Journal: Blood 20110922

Title: Modulation of biomarkers related to tumor initiation and promotion in mouse skin by a natural β-glucuronidase inhibitor and its precursors.

Journal: Oncology reports 20110901

Title: FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease.

Journal: Gastroenterology 20110901

Title: A multicentre comparative study on the efficacy of intravenous ferric carboxymaltose and iron sucrose for correcting preoperative anaemia in patients undergoing major elective surgery.

Journal: British journal of anaesthesia 20110901

Title: IBD: Intravenous iron in IBD--what's the best preparation?

Journal: Nature reviews. Gastroenterology & hepatology 20110726

Title: Safety profiles of total dose infusion of low-molecular-weight iron dextran and high-dose iron sucrose in renal patients.

Journal: Hemodialysis international. International Symposium on Home Hemodialysis 20110701

Title: In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components.

Journal: Journal of physiology and biochemistry 20110601

Title: Evidence of benzilic rearrangement during the electrochemical oxidation of D-glucose to D-glucaric acid.

Journal: Carbohydrate research 20110301

Title: The therapeutic equivalence of complex drugs.

Journal: Regulatory toxicology and pharmacology : RTP 20110201

Title: Evaluation of 99mTc-glucarate as a breast cancer imaging agent in a xenograft animal model.

Journal: Nuclear medicine and biology 20110201

Title: The role of MafA in regulating cytokine expression in pancreatic beta cells.

Journal: The Journal of biological chemistry 20110121

Title: Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells.

Journal: The Journal of biological chemistry 20110114

Title: Proteinuria induced by parenteral iron in chronic kidney disease--a comparative randomized controlled trial.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110101

Title: Physicochemical and toxicological characterization of a new generic iron sucrose preparation.

Journal: Arzneimittel-Forschung 20110101

Title: Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways.

Journal: Journal of biochemical and molecular toxicology 20110101

Title: Differences in spontaneously reported hypersensitivity and serious adverse events for intravenous iron preparations: comparison of Europe and North America.

Journal: Arzneimittel-Forschung 20110101

Title: Assessment of the extent of oxidative stress induced by intravenous ferumoxytol, ferric carboxymaltose, iron sucrose and iron dextran in a nonclinical model.

Journal: Arzneimittel-Forschung 20110101

Title: Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial.

Journal: High altitude medicine & biology 20110101

Title: Evaluation of toxicity and oxidative stress induced by intravenous iron isomaltoside 1000 in a nonclinical model.

Journal: Arzneimittel-Forschung 20110101

Title: A brief evaluation of tumor imaging in mice with 99mTc-glucarate including a comparison with 18F-FDG.

Journal: Current radiopharmaceuticals 20110101

Title: Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy.

Journal: JNMA; journal of the Nepal Medical Association 20110101

Title: Postoperative high-dose intravenous iron sucrose with low dose erythropoietin therapy after total hip replacement.

Journal: The Korean journal of internal medicine 20101201

Title: 99mTc-glucarate kinetics differentiate normal, stunned, hibernating, and nonviable myocardium in a perfused rat heart model.

Journal: European journal of nuclear medicine and molecular imaging 20101001

Title: The health care cost of intravenous iron treatment in IBD patients depends on the economic evaluation perspective.

Journal: Journal of Crohn's & colitis 20101001

Title: Oxidative stress in hemodialysis patients receiving intravenous iron therapy and the role of N-acetylcysteine in preventing oxidative stress.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100901

Title: The plastid hexokinase pHXK: a node of convergence for sugar and plastid signals in Arabidopsis.

Journal: FEBS letters 20100820

Title: Parenteral iron formulations differentially affect MCP-1, HO-1, and NGAL gene expression and renal responses to injury.

Journal: American journal of physiology. Renal physiology 20100801

Title: Randomized evaluation of efficacy and safety of ferric carboxymaltose in patients with iron deficiency anaemia and impaired renal function (REPAIR-IDA): rationale and study design.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100701

Title: Eosinophilic fasciitis secondary to intravenous iron infusions.

Journal: Dermatology online journal 20100515

Title: Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli.

Journal: Metabolic engineering 20100501

Title: Labile plasma iron generation after intravenous iron is time-dependent and transitory in patients undergoing chronic hemodialysis.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20100401

Title: Maintenance of elevated versus physiological iron indices in non-anaemic patients with chronic kidney disease: a randomized controlled trial.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301

Title: Blood transfusion reduction with intravenous iron in gynecologic cancer patients receiving chemotherapy.

Journal: Gynecologic oncology 20100301

Title: Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma.

Journal: Laboratory investigation; a journal of technical methods and pathology 20100301

Title: Early hepatic insulin resistance in mice: a metabolomics analysis.

Journal: Molecular endocrinology (Baltimore, Md.) 20100301

Title: Calcium glucarate inhibits DMBA-induced oral carcinogenesis in the hamster: histomorphometric evaluation.

Journal: Anticancer research 20100301

Title: Randomized clinical trial on acute effects of i.v. iron sucrose during haemodialysis.

Journal: Nephrology (Carlton, Vic.) 20100301

Title: Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice.

Journal: Cancer prevention research (Philadelphia, Pa.) 20100201

Title: Iron replacement therapy: assessing today's options to prepare for bundling.

Journal: Nephrology news & issues 20100201

Title: Comparison of parenteral iron sucrose and ferric chloride during erythropoietin therapy of haemodialysis patients.

Journal: Nephrology (Carlton, Vic.) 20100201

Title: Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis.

Journal: Digestive diseases (Basel, Switzerland) 20100101

Title: In vitro study on the effects of iron sucrose, ferric gluconate and iron dextran on redox-active iron and oxidative stress.

Journal: Arzneimittel-Forschung 20100101

Title: Effect of different intravenous iron preparations on lymphocyte intracellular reactive oxygen species generation and subpopulation survival.

Journal: BMC nephrology 20100101

Title: A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model.

Journal: Platelets 20100101

Title: Evaluation of patients with head and neck cancer by means of 99mTc-glucarate.

Journal: Journal of nuclear medicine technology 20091201

Title: [Treating severe acute anemia due to vaginal bleeding in the Jehovah's Witness: a report of 2 cases].

Journal: Revista espanola de anestesiologia y reanimacion 20091201

Title: Convenient large-scale synthesis of D-glucaro-1,4:6,3-dilactone.

Journal: The Journal of organic chemistry 20091106

Title: A pilot evaluation of the long-term effect of combined therapy with intravenous iron sucrose and erythropoietin in elderly patients with advanced chronic heart failure and cardio-renal anemia syndrome: influence on neurohormonal activation and clinical outcomes.

Journal: Journal of cardiac failure 20091101

Title: Significance of urinary glucaric acid measurement and its application to paclitaxel therapy.

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20091101

Title: Intravenous iron in inflammatory bowel disease.

Journal: World journal of gastroenterology 20091007

Title: Efficacy of preoperative recombinant human erythropoietin administration for reducing transfusion requirements in patients undergoing surgery for hip fracture repair. An observational cohort study.

Journal: Vox sanguinis 20091001

Title: Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.

Journal: Diabetes 20090901

Title: A major role for perifornical orexin neurons in the control of glucose metabolism in rats.

Journal: Diabetes 20090901

Title: Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells.

Journal: Endocrine 20090801

Title: Synthetic protein scaffolds provide modular control over metabolic flux.

Journal: Nature biotechnology 20090801

Title: Synthetic metabolic pipelines.

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Title: Comparison of serum ferritin and transferrin saturation values associated with two i.v. iron formulations in hemodialysis patients.

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Title: Molecular imaging of cell death.

Journal: Methods (San Diego, Calif.) 20090601

Title: Comparison of intravenous iron sucrose versus low-molecular-weight iron dextran in chronic kidney disease.

Journal: Journal of renal care 20090601

Title: Parenteral iron use: possible contribution to exceeding target hemoglobin in hemodialysis patients.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20090301

Title: Comparison of cerebrospinal fluid obtained by ventricular endoscopy and by lumbar puncture in patients with hydrocephalus secondary to neurocysticercosis.

Journal: Surgical neurology 20090301

Title: Treatment of restless legs syndrome with iron infusion therapy.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20090301

Title: [Intravenous iron sucrose in maintenance dialysis patients with renal anemia: a clinical study].

Journal: Zhonghua yi xue za zhi 20090224

Title: The role of iron supplementation during epoietin treatment for cancer-related anemia.

Journal: Medical oncology (Northwood, London, England) 20090101

Title: In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage.

Journal: Journal of applied toxicology : JAT 20090101

Title: The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: analysis of 9.5 years of prospectively collected data.

Journal: BMC nephrology 20090101

Title: Intravenous iron sucrose changes the intraperitoneal homeostasis.

Journal: Blood purification 20090101

Title: Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study.

Journal: Acta haematologica 20090101

Title: Differences between original intravenous iron sucrose and iron sucrose similar preparations.

Journal: Arzneimittel-Forschung 20090101

Title: The effect of high glucose on SERT, the human plasmalemmal serotonin transporter.

Journal: Nutritional neuroscience 20081201

Title: Ascorbyl free radical reflects catalytically active iron after intravenous iron saccharate injection.

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Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20081101

Title: [The biological role of D-glucaric acid and its derivatives: potential use in medicine].

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Title: Intravenous iron exacerbates oxidative DNA damage in peripheral blood lymphocytes in chronic hemodialysis patients.

Journal: Journal of the American Society of Nephrology : JASN 20080901

Title: Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases.

Journal: The Journal of pharmacy and pharmacology 20080901

Title: Intravenous iron in chronic kidney disease: haemoglobin change shortly after treatment of patients neither on dialysis nor on erythropoietin.

Journal: Journal of renal care 20080901

Title: Clinical applications of urinary organic acids. Part I: Detoxification markers.

Journal: Alternative medicine review : a journal of clinical therapeutic 20080901

Title: Effects of Mirasol PRT treatment on storage lesion development in plasma-stored apheresis-derived platelets compared to untreated and irradiated units.

Journal: Transfusion 20080801

Title: Intravenous iron administration in a short-stay hospital setting.

Journal: Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20080801

Title: Protective effects of D-glucaro-1,4-lactone against oxidative modifications in blood platelets.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20080701

Title: Could 99mTc-glucarate be used to evaluate tumour necrosis? In vitro and in vivo studies in leukaemic tumour cell line U937.

Journal: European journal of nuclear medicine and molecular imaging 20080701

Title: The role of intravenous iron in anemia management and transfusion avoidance.

Journal: Transfusion 20080501

Title: D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets.

Journal: Cell biology and toxicology 20080401

Title: Low-molecular weight iron dextran and iron sucrose have similar comparative safety profiles in chronic kidney disease.

Journal: Kidney international 20080301

Title: Quorum sensing detected by atomic force microscopy imaging of corrals surrounding multicellular arrangement of bacteria.

Journal: Microscopy research and technique 20080201

Title: Evaluating the protective role of ischaemic preconditioning in rat hearts using a stationary small-animal SPECT imager and 99mTc-glucarate.

Journal: Nuclear medicine communications 20080201

Title: Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease.

Journal: Kidney international 20080201

Title: Chemical reactions of vitamin C with intravenous-iron formulations.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080101

Title: Comparative toxicity and cell-tissue distribution study on nanoparticular iron complexes using avian embryos and HepG2-cells.

Journal: Translational research : the journal of laboratory and clinical medicine 20080101

Title: [Improvement of urinary d-glucaric acid assay and its application].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101

Title: Intravenous iron sucrose in Chinese hemodialysis patients with renal anemia.

Journal: Blood purification 20080101

Title: Intravenous iron sucrose in peritoneal dialysis patients with renal anemia.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20080101

Title: Intravenous iron without erythropoietin for the treatment of iron deficiency anemia in patients with moderate to severe congestive heart failure and chronic kidney insufficiency.

Journal: Journal of nephrology 20080101

Title: The comparative safety of various intravenous iron preparations in chronic kidney disease patients.

Journal: Renal failure 20080101

Title: A 12-week randomised study comparing intravenous iron sucrose versus oral ferrous sulphate for treatment of postpartum anemia.

Journal: Acta obstetricia et gynecologica Scandinavica 20080101

Title: Seasonal variation of trehalose and glycerol concentrations in winter snow-active insects.

Journal: Cryo letters 20080101

Title: Effect of intravenous iron supplementation on hepatic cytochrome P450 3A4 activity in hemodialysis patients: a prospective, open-label study.

Journal: Clinical therapeutics 20071201

Title: Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency.

Journal: Journal of the American College of Cardiology 20071023

Title: [Drug-induced osteomalacia].

Journal: Clinical calcium 20071001

Title: Iron sucrose causes greater proteinuria than ferric gluconate in non-dialysis chronic kidney disease.

Journal: Kidney international 20070901

Title: Intravenous iron.

Journal: The New England journal of medicine 20070705

Title: [Intravenous treatment of postpartum anemia with trivalent ferrum preparation].

Journal: Ceska gynekologie 20070501

Title: [Current recommendations for the treatment of iron deficiency anemia].

Journal: Revue medicale suisse 20070404

Title: Administration of exogenous erythropoietin beta affects lipid peroxidation and serum paraoxonase-1 activity and concentration in predialysis patients with chronic renal disease and anaemia.

Journal: Clinical and experimental pharmacology & physiology 20070401

Title: Safe administration of iron sucrose in a patient with a previous hypersensitivity reaction to ferric gluconate.

Journal: Pharmacotherapy 20070401

Title: [Administration of iron-containing drugs in non-dialyzed patients with chronic kidney disease].

Journal: Polskie Archiwum Medycyny Wewnetrznej 20070401

Title: alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution.

Journal: The Journal of biological chemistry 20070302

Title: Comparison of oxidative stress markers after intravenous administration of iron dextran, sodium ferric gluconate, and iron sucrose in patients undergoing hemodialysis.

Journal: Pharmacotherapy 20070301

Title: Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20070201

Title: Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Effect of intravenous iron sucrose on oxidative stress in peritoneal dialysis patients.

Journal: Renal failure 20070101

Title: Esterification of select polyols with D-glucaric acid as model reactions for esterification of starch.

Journal: Carbohydrate research 20061127

Title: [Ferropenic anemia: some comments].

Journal: Medicina clinica 20061125

Title: Apoptotic stress pathway activation mediated by iron on endothelial cells in vitro.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101

Title: Intravenous versus oral iron therapy for postpartum anaemia.

Journal: BJOG : an international journal of obstetrics and gynaecology 20061101

Title: Association of different intravenous iron preparations with risk of bacteremia in maintenance hemodialysis patients.

Journal: Clinical nephrology 20061101

Title: Iron sucrose induced morphological and functional changes in the rat kidney.

Journal: Translational research : the journal of laboratory and clinical medicine 20061101

Title: Re: blood transfusion and orthognathic surgery a thing of the past?

Journal: The British journal of oral & maxillofacial surgery 20061001

Title: Impact of iron sucrose therapy on leucocyte surface molecules and reactive oxygen species in haemodialysis patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061001

Title: Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants.

Journal: Planta 20060901

Title: Acute injury with intravenous iron and concerns regarding long-term safety.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20060901

Title: Parenteral iron compounds: potent oxidants but mainstays of anemia management in chronic renal disease.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20060901

Title: Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes.

Journal: Inorganic chemistry 20060821

Title: Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902.

Journal: European journal of heart failure 20060801

Title: Proinflammatory effects of iron sucrose in chronic kidney disease.

Journal: Kidney international 20060401

Title: [Postpartum and early postoperative anemia after gynecological surgery: treatment with intravenous iron].

Journal: Revista espanola de anestesiologia y reanimacion 20060401

Title: (99m)Tc-glucarate imaging for the early detection of infarct in partially reperfused canine myocardium.

Journal: European journal of nuclear medicine and molecular imaging 20060301

Title: Update on adverse drug events associated with parenteral iron.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060201

Title: Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects.

Journal: Kidney international 20060201

Title: The effect of intravenous iron on oxidative stress in hemodialysis patients at various levels of vitamin C.

Journal: Blood purification 20060101

Title: [Use of Venofer in management of anemia in cancer patients].

Journal: Voprosy onkologii 20060101

Title: Intravenous iron therapy: well-tolerated, yet not harmless.

Journal: European journal of clinical investigation 20051201

Title: Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects.

Journal: Journal of pharmacological sciences 20051201

Title: Intravenous iron increases labile serum iron but does not impair forearm blood flow reactivity in dialysis patients.

Journal: Kidney international 20051201

Title: para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents.

Journal: Organic & biomolecular chemistry 20051107

Title: Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20051101

Title: Parenteral iron therapy: a single institution's experience over a 5-year period.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20051101

Title: [Post-haemodilution anaemia in paediatric cardiac surgery: benefit of intravenous iron therapy].

Journal: Annales francaises d'anesthesie et de reanimation 20051001

Title: Parenteral iron treatment induces MCP-1 accumulation in plasma, normal kidneys, and in experimental nephropathy.

Journal: Kidney international 20051001

Title: Trends in intravenous iron use among dialysis patients in the United States (1994-2002).

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20051001

Title: Relationship between iron replacement and hepatic functions in hepatitis C virus-positive chronic haemodialysis patients.

Journal: Nephrology (Carlton, Vic.) 20051001

Title: Crystal structure and aqueous solubility of ammonium D-glucarate.

Journal: Carbohydrate research 20050926

Title: Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease.

Journal: Scandinavian journal of gastroenterology 20050901

Title: Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.

Journal: Therapeutic drug monitoring 20050801

Title: MRP-1 protein expression and glutathione content of in vitro tumor cell lines derived from human glioma carcinoma U-87-MG do not interact with 99mTc-glucarate uptake.

Journal: Cancer biotherapy & radiopharmaceuticals 20050801

Title: Hypersensitivity reactions and deaths associated with intravenous iron preparations.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701

Title: Combination of intravenous iron sucrose and ascorbic acid in hemodialysis patients.

Journal: Kidney international 20050701

Title: Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats.

Journal: The Journal of laboratory and clinical medicine 20050701

Title: Intravenous iron in a primary-care clinic.

Journal: American journal of hematology 20050401

Title: Hydroxyl stereochemistry and amine number within poly(glycoamidoamine)s affect intracellular DNA delivery.

Journal: Journal of the American Chemical Society 20050309

Title: Parenteral iron therapy in treatment of anemia in end-stage renal disease patients: a comparative study between iron saccharate and gluconate.

Journal: Nephron. Clinical practice 20050101

Title: Effect of sucrose containing iron (II) on dental biofilm and enamel demineralization in situ.

Journal: Caries research 20050101

Title: [Evaluation of the efficacy of intravenous iron III-hydroxide saccharate for treating adult patients with iron deficiency anemia].

Journal: Revista da Associacao Medica Brasileira (1992) 20050101

Title: Elevated cardiac troponin T in hemodialysis patients receiving more intravenous iron sucrose.

Journal: Renal failure 20041101

Title: Patients with pertrochanteric hip fracture may benefit from preoperative intravenous iron therapy: a pilot study.

Journal: Transfusion 20041001

Title: Endothelial injury markers with high-dose intravenous iron therapy in renal failure.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20041001

Title: [Safety and usefulness of parenteral iron in the management of anemia due to hip fracture in the elderly].

Journal: Medicina clinica 20040911

Title: Possible induction of cholinesterase in epileptic patients treated with anticonvulsant drugs: relationship with lipoprotein levels.

Journal: Journal of clinical pharmacology 20040901

Title: Transferrin saturation with intravenous irons: an in vitro study.

Journal: Kidney international 20040901

Title: Iron sucrose in hemodialysis patients: safety of replacement and maintenance regimens.

Journal: Kidney international 20040901

Title: Effects of different dialysis membranes on serum concentrations of epoetin alfa, darbepoetin alfa, enoxaparin, and iron sucrose during dialysis.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040901

Title: Rapid, high-dose intravenous iron sucrose therapy in 2 Jehovah's Witness patients with severe anemia, iron deficiency and chronic kidney disease.

Journal: Clinical nephrology 20040801

Title: Oxidative stress from rapid versus slow intravenous iron replacement in haemodialysis patients.

Journal: Nephrology (Carlton, Vic.) 20040801

Title: Parenteral iron nephrotoxicity: potential mechanisms and consequences.

Journal: Kidney international 20040701

Title: Dose-dependent effect of parenteral iron therapy on bleomycin-detectable iron in immune apheresis patients.

Journal: Kidney international 20040701

Title: 99mTc glucarate high-resolution imaging of drug sensitive and drug resistant human breast cancer xenografts in SCID mice.

Journal: Nuclear medicine communications 20040701

Title: High-resolution imaging with (99m)Tc-glucarate for assessing myocardial injury in rat heart models exposed to different durations of ischemia with reperfusion.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040701

Title: New poly(d-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells.

Journal: Journal of the American Chemical Society 20040623

Title: Vanadium(IV,V) complexes of D-saccharic and mucic acids in aqueous solution.

Journal: Dalton transactions (Cambridge, England : 2003) 20040621

Title: Non-transferrin-bound iron in the serum of hemodialysis patients who receive ferric saccharate: no correlation to peroxide generation.

Journal: Journal of the American Society of Nephrology : JASN 20040601

Title: Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: Parenteral iron therapy options.

Journal: American journal of hematology 20040501

Title: Mechanisms of lung cancer chemoprevention by D-glucarate.

Journal: Chest 20040501

Title: Modulation of biomarkers during chemoprevention of mouse lung tumorigenesis by D-glucarate.

Journal: Chest 20040501

Title: Treatment of anaemia in inflammatory bowel disease with iron sucrose.

Journal: Scandinavian journal of gastroenterology 20040501

Title: The use of androgens in anaemia resistant to erythropoietin and i.v. iron in patients with heart and renal failure.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401

Title: Early detection of infarct in reperfused canine myocardium using 99mTc-glucarate.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040401

Title: Labile iron in parenteral iron formulations: a quantitative and comparative study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040301

Title: Decolorization of synthetic dyes using a copper complex with glucaric acid.

Journal: Chemosphere 20040101

Title: Determination of iron sucrose (Venofer) or iron dextran (DexFerrum) removal by hemodialysis: an in-vitro study.

Journal: BMC nephrology 20040101

Title: Safety of iron sucrose in hemodialysis patients intolerant to other parenteral iron products.

Journal: Nephron. Clinical practice 20040101

Title: [Comparison of intravenous ascorbic acid versus intravenous iron for functional iron deficiency in hemodialysis patients].

Journal: Nihon Jinzo Gakkai shi 20040101

Title: [How to avoid a haemotransfusion which is not lifesaving? (our experience with administration of intravenous iron to pregnant women and young mothers)].

Journal: Akusherstvo i ginekologiia 20040101

Title: Effect of iron sucrose on human peritoneal mesothelial cells.

Journal: European journal of clinical investigation 20031201

Title: Reactivity of iron compounds.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20031101

Title: Intravenous iron therapy in chronic kidney disease and peritoneal dialysis patients.

Journal: Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20031001

Title: Assessment of copper status in epileptic patients treated with anticonvulsant drugs by measuring the specific oxidase activity of ceruloplasmin.

Journal: Epilepsy research 20031001

Title: Relationship between PCBs in blood and D-glucaric acid in urine.

Journal: Toxicology letters 20030915

Title: Vibrio vulnificus infection in a hemodialysis patient receiving intravenous iron therapy.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030901

Title: [Indications and practical management of parenteral iron therapy].

Journal: Wiener klinische Wochenschrift 20030624

Title: Detoxifying cancer causing agents to prevent cancer.

Journal: Integrative cancer therapies 20030601

Title: Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models.

Journal: Nuclear medicine communications 20030501

Title: Non-invasive in vivo imaging of myocardial apoptosis and necrosis.

Journal: European journal of nuclear medicine and molecular imaging 20030401

Title: The first fluorescent sensor for D-glucarate based on the cooperative action of boronic acid and guanidinium groups.

Journal: Chemical communications (Cambridge, England) 20030321

Title: Chronic use of sodium ferric gluconate complex in hemodialysis patients: safety of higher-dose (> or =250 mg) administration.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301

Title: Calcium glucarate prevents tumor formation in mouse skin.

Journal: Biomedical and environmental sciences : BES 20030301

Title: Early prediction of response to intravenous iron supplementation by reticulocyte haemoglobin content and high-fluorescence reticulocyte count in haemodialysis patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201

Title: Clinical review of the newer intravenous iron therapy options.

Journal: Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20030201

Title: Myocardial kinetics of Tc-99m glucarate in low flow, hypoxia, and aglycemia.

Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20030101

Title: The effects of intravenous iron treatment on oxidant stress and erythrocyte deformability in hemodialysis patients.

Journal: Scandinavian journal of urology and nephrology 20030101

Title: Safety of high doses of non-dextran irons.

Journal: Seminars in dialysis 20030101

Title: [Changes in iron metabolism and erythropoietin requirements after the switch from ferric gluconate to iron saccharose. Is it worth the increased expense?].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20030101

Title: [Use of venofer for iron deficiency correction in patients undergoing programmed hemodialysis].

Journal: Terapevticheskii arkhiv 20030101

Title: [Experimental systemic enzyme therapy of gouty and primary glomerulonephritis].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20030101

Title: [Antiphospholipid antibodies as a cause of adverse pregnancy outcome. Therapeutic approach].

Journal: Akusherstvo i ginekologiia 20030101

Title: Iron sucrose: the oldest iron therapy becomes new.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20021201

Title: Differential effects of Saint John's Wort (hypericum perforatum) on the urinary excretion of D-glucaric acid and 6beta-hydroxycortisol in healthy volunteers.

Journal: European journal of clinical pharmacology 20021201

Title: Induction of protein oxidation by intravenous iron in hemodialysis patients: role of inflammation.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20021101

Title: Tolerance and efficacy of intravenous iron saccharate for iron deficiency anemia in children and adolescents receiving long-term parenteral nutrition.

Journal: Clinical nutrition (Edinburgh, Scotland) 20021001

Title: [A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs].

Journal: Revista de neurologia 20021001

Title: Calcium-D-glucarate.

Journal: Alternative medicine review : a journal of clinical therapeutic 20020801

Title: Parenteral iron formulations: a comparative toxicologic analysis and mechanisms of cell injury.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020701

Title: Parenteral iron therapy in obstetrics: 8 years experience with iron-sucrose complex.

Journal: The British journal of nutrition 20020701

Title: Determination of the side-products formed during the nitroxide-mediated bleach oxidation of glucose to glucaric acid.

Journal: Carbohydrate research 20020605

Title: Identification and characterization of the Bacillus subtilis D-glucarate/galactarate utilization operon ycbCDEFGHJ.

Journal: FEMS microbiology letters 20020507

Title: D-glucaric acid in common duct bile and relation to choledocholithiasis.

Journal: Scandinavian journal of gastroenterology 20020401

Title: Ferric saccharate induces oxygen radical stress and endothelial dysfunction in vivo.

Journal: European journal of clinical investigation 20020301

Title: Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion.

Journal: European journal of clinical investigation 20020301

Title: Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route.

Journal: American journal of obstetrics and gynecology 20020301

Title: 99mTc-glucarate for detection of isoproterenol-induced myocardial infarction in rats.

Journal: International journal of pharmaceutics 20020221

Title: Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment.

Journal: Clinical laboratory 20020101

Title: Iron sucrose or ferric gluconate?

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201

Title: Facile nitroxide-mediated oxidations of D-glucose to D-glucaric acid.

Journal: Carbohydrate research 20011101

Title: Risk of bacterial infection in patients under intravenous iron therapy: dose versus length of treatment.

Journal: Artificial organs 20011101

Title: A randomized, controlled parallel-group trial on efficacy and safety of iron sucrose (Venofer) vs iron gluconate (Ferrlecit) in haemodialysis patients treated with rHuEpo.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010601

Title: The effect of i.v. iron alone or in combination with low-dose erythropoietin in the rapid correction of anemia of chronic renal failure in the predialysis period.

Journal: Clinical nephrology 20010301

Title: [Iron deficiency. When parenteral substitution?].

Journal: MMW Fortschritte der Medizin 20010208

Title: Efficacy and safety of iron sucrose for iron deficiency in patients with dialysis-associated anemia: North American clinical trial.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20010201

Title: Effect of intravenous iron supplementation on erythropoiesis in erythropoietin-treated premature infants.

Journal: Pediatrics 20010101

Title: New possibilities in scintigraphy detection of carbon monoxide cardiotoxicity.

Journal: Przeglad lekarski 20010101

Title: Experience with a large dose (500 mg) of intravenous iron dextran and iron saccharate in peritoneal dialysis patients.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

Title: Re: Experience with a large dose (500 mg) of intravenous iron dextran and iron saccharate in peritoneal dialysis patients.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

Title: Aggressive therapy of congestive heart failure and associated chronic renal failure with medications and correction of anemia stops or slows the progression of both diseases.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101

Title: Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats.

Journal: Cancer letters 19840801

Title: Effect of D-Glucarates on basic antibiotic-induced renal damage in rats.

Journal: The Journal of antibiotics 19760201

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Tags:5793-89-5 Molecular Formula|5793-89-5 MDL|5793-89-5 SMILES|5793-89-5 Calcium (2R,3S,4S,5S)-2,3,4,5-tetrahydroxyhexanedioate tetrahydrate