Home Other Building Blocks 57477-39-1
57477-39-1,MFCD01861184
Catalog No.:AA00ECA9

57477-39-1 | Brl 54443

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
98%
in stock  
$54.00   $38.00
- +
100mg
98%
in stock  
$120.00   $84.00
- +
250mg
98%
in stock  
$234.00   $164.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ECA9
Chemical Name:
Brl 54443
CAS Number:
57477-39-1
Molecular Formula:
C14H18N2O
Molecular Weight:
230.3055
MDL Number:
MFCD01861184
SMILES:
CN1CCC(CC1)c1c[nH]c2c1cc(O)cc2
Properties
Computed Properties
 
Complexity:
263  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.5  

Literature

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Klein MT, et al. Toward selective drug development for the human 5-hydroxytryptamine 1E receptor: a comparison of 5-hydroxytryptamine 1E and 1F receptor structure-affinity relationships. J Pharmacol Exp Ther. 2011 Jun;337(3):860-867.

Title: McKune CM, et al. Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling. J Pharmacol Exp Ther. 2001 Apr;297(1):88-95.

Title: Klein MT, et al. Distribution of 5-ht(1E) receptors in the mammalian brain and cerebral vasculature: an immunohistochemical and pharmacological study. Br J Pharmacol. 2012 Jun;166(4):1290-302.

Title: Granados-Soto V, et al. The role of peripheral 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F serotonergic receptors in the reduction of nociception in rats. Neuroscience. 2010 Jan 20;165(2):561-8.

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SDS
Tags:57477-39-1 Molecular Formula|57477-39-1 MDL|57477-39-1 SMILES|57477-39-1 Brl 54443