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61909-81-7,MFCD32661415
Catalog No.:AA00EFJS

61909-81-7 | Solutol HS 15

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Purity
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5g
Hyroxyl Value(90-110mg);Acid Value(0.3mg)
in stock  
$21.00   $15.00
- +
25g
Hyroxyl Value(90-110mg);Acid Value(0.3mg)
in stock  
$68.00   $48.00
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100g
Hyroxyl Value(90-110mg);Acid Value(0.3mg)
in stock  
$245.00   $171.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EFJS
Chemical Name:
Solutol HS 15
CAS Number:
61909-81-7
Molecular Formula:
C20H40NO4
Molecular Weight:
358.5359
MDL Number:
MFCD32661415
SMILES:
CCCCCCC(CCCCCCCCCCC(=O)OCCO)O.[N]
NSC Number:
7395
Properties
Computed Properties
 
Complexity:
268  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
19  
Undefined Atom Stereocenter Count:
1  
XLogP3:
5.9  

Literature

Title: A propofol microemulsion with low free propofol in the aqueous phase: formulation, physicochemical characterization, stability and pharmacokinetics.

Journal: International journal of pharmaceutics 20121015

Title: Pharmaceutical excipients influence the function of human uptake transporting proteins.

Journal: Molecular pharmaceutics 20120904

Title: CriticalSorb: a novel efficient nasal delivery system for human growth hormone based on Solutol HS15.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20120820

Title: In-situ phase transition from microemulsion to liquid crystal with the potential of prolonged parenteral drug delivery.

Journal: International journal of pharmaceutics 20120715

Title: Physicochemical characterization and an injection formulation study of water insoluble ZCVI₄-2, a novel NO-donor anticancer compound.

Journal: Archives of pharmacal research 20120701

Title: In situ controlled crystallization as a tool to improve the dissolution of Glibenclamide.

Journal: International journal of pharmaceutics 20120530

Title: Preparation and pharmacokinetic evaluation of curcumin solid dispersion using Solutol® HS15 as a carrier.

Journal: International journal of pharmaceutics 20120315

Title: Ferrociphenol lipid nanocapsule delivery by mesenchymal stromal cells in brain tumor therapy.

Journal: International journal of pharmaceutics 20120214

Title: Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133.

Journal: International journal of pharmaceutics 20120214

Title: In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model.

Journal: International journal of pharmaceutics 20120214

Title: Nanohybrid systems of non-ionic surfactant inserting liposomes loading paclitaxel for reversal of multidrug resistance.

Journal: International journal of pharmaceutics 20120117

Title: A comparative study of non-lipid nanoemulsion of propofol with solutol and propofol emulsion with lecithin.

Journal: Revista brasileira de anestesiologia 20120101

Title: Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110901

Title: Self-microemulsifying drug delivery system for improved oral bioavailability of dipyridamole: preparation and evaluation.

Journal: Archives of pharmacal research 20110701

Title: Case studies with new excipients: development, implementation and regulatory approval.

Journal: Therapeutic delivery 20110701

Title: Inner ear biocompatibility of lipid nanocapsules after round window membrane application.

Journal: International journal of pharmaceutics 20110214

Title: [Effect of three penetration enhancers on corneal permeability of mangiferin in vitro].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201

Title: Formulation and evaluation of an alternative triglyceride-free propofol microemulsion.

Journal: Archives of pharmacal research 20100901

Title: The effect of novel surfactants and Solutol HS 15 on paclitaxel aqueous solubility and permeability across a Caco-2 monolayer.

Journal: Journal of pharmaceutical sciences 20100801

Title: Antinociceptive activity of Delta9-tetrahydrocannabinol non-ionic microemulsions.

Journal: International journal of pharmaceutics 20100630

Title: [Studies on preparation and dissolution test in vitro of sustained-release dropping pills of curcumin].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101

Title: Emulsifiers' composition modulates venous irritation of the nanoemulsions as a lipophilic and venous irritant drug delivery system.

Journal: AAPS PharmSciTech 20090901

Title: The encapsulation of DNA molecules within biomimetic lipid nanocapsules.

Journal: Biomaterials 20090601

Title: Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results.

Journal: International journal of pharmaceutics 20090105

Title: In vitro permeation studies of nanoemulsions containing ketoprofen as a model drug.

Journal: Drug delivery 20080901

Title: Nano-emulsions and nanocapsules by the PIT method: an investigation on the role of the temperature cycling on the emulsion phase inversion.

Journal: International journal of pharmaceutics 20071101

Title: Preparation and characterization of a self-emulsifying pellet formulation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070501

Title: Formulation of sustained release nanoparticles loaded with a tripentone, a new anticancer agent.

Journal: International journal of pharmaceutics 20060831

Title: Mechanistic study of solubility enhancement of nifedipine using vitamin E TPGS or solutol HS-15.

Journal: Drug delivery 20060101

Title: Convection-compensating diffusion experiments with phase-sensitive double-quantum filtering.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20050601

Title: In vitro investigation on the impact of the surface-active excipients Cremophor EL, Tween 80 and Solutol HS 15 on the metabolism of midazolam.

Journal: Biopharmaceutics & drug disposition 20040101

Title: Impact of Solutol HS 15 on the pharmacokinetic behavior of midazolam upon intravenous administration to male Wistar rats.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030701

Title: The influence of lipid nanocapsule composition on their size distribution.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030101

Title: Improved oral bioavailability of cyclosporin A in male Wistar rats. Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension.

Journal: International journal of pharmaceutics 20021001

Title: Solutol and cremophor products as new additives in suppository formulation.

Journal: Drug development and industrial pharmacy 20020101

Title: Shubber S, et al. Mechanism of mucosal permeability enhancement of CriticalSorb (Solutol HS15) investigated in vitro in cell cultures. Pharm Res. 2015 Feb;32(2):516-27.

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