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73945-46-7,MFCD09264322
Catalog No.:AA00FB02

73945-46-7 | 7-Chloro-l-tryptophan

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100mg
97%
in stock  
$70.00   $49.00
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250mg
97%
in stock  
$106.00   $75.00
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1g
97%
in stock  
$421.00   $295.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FB02
Chemical Name:
7-Chloro-l-tryptophan
CAS Number:
73945-46-7
Molecular Formula:
C11H11ClN2O2
Molecular Weight:
238.6702
MDL Number:
MFCD09264322
SMILES:
N[C@H](C(=O)O)Cc1c[nH]c2c1cccc2Cl
Properties
Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
-0.4  

Literature

Title: Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor.

Journal: Journal of the American Chemical Society 20111207

Title: Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis.

Journal: Angewandte Chemie (International ed. in English) 20110321

Title: Biosynthetic gene cluster for the cladoniamides, bis-indoles with a rearranged scaffold.

Journal: PloS one 20110101

Title: Effects of nutrients on quorum signals and secondary metabolite productions of Burkholderia sp. O33.

Journal: Journal of microbiology and biotechnology 20091001

Title: Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly.

Journal: Journal of the American Chemical Society 20081029

Title: Halogenase genes in nonribosomal peptide synthetase gene clusters of Microcystis (cyanobacteria): sporadic distribution and evolution.

Journal: Molecular biology and evolution 20080901

Title: The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.

Journal: Biochemistry 20071030

Title: Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases.

Journal: Biochemistry 20070206

Title: Preliminary crystallographic characterization of PrnB, the second enzyme in the pyrrolnitrin biosynthetic pathway.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20061101

Title: Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH.

Journal: Biochemistry 20060627

Title: Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination.

Journal: Science (New York, N.Y.) 20050930

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