Home Other Building Blocks 668467-91-2
668467-91-2,MFCD09037562
Catalog No.:AA00FBGD

668467-91-2 | LDN-57444

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$21.00   $15.00
- +
5mg
98%
in stock  
$57.00   $40.00
- +
10mg
98%
in stock  
$96.00   $68.00
- +
50mg
98%
in stock  
$287.00   $201.00
- +
100mg
98%
in stock  
$433.00   $303.00
- +
250mg
98%
in stock  
$583.00   $408.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FBGD
Chemical Name:
LDN-57444
CAS Number:
668467-91-2
Molecular Formula:
C17H11Cl3N2O3
Molecular Weight:
397.6398
MDL Number:
MFCD09037562
SMILES:
CC(=O)ON=C1c2cc(Cl)ccc2N(C1=O)Cc1cc(Cl)ccc1Cl
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
571  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
4.6  

Literature

Title: Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.

Journal: Journal of neurochemistry 20120301

Title: Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090617

Title: Liu Y, et al. Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem Biol. 2003 Sep;10(9):837-46.

Title: Gong B, et al. Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory. Cell. 2006 Aug 25;126(4):775-88.

Title: Tan YY, et al. Endoplasmic reticulum stress contributes to the cell death induced by UCH-L1 inhibitor. Mol Cell Biochem. 2008 Nov;318(1-2):109-15.

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Tags:668467-91-2 Molecular Formula|668467-91-2 MDL|668467-91-2 SMILES|668467-91-2 LDN-57444