Home Carboxes 690270-29-2
690270-29-2,MFCD18251433
Catalog No.:AA00FBWL

690270-29-2 | 4'-C-Azidocytidine 2',3',5'-tris(2-methylpropanoate)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥99%
in stock  
$1,518.00   $1,063.00
- +
25mg
≥99%
in stock  
$3,345.00   $2,342.00
- +
100mg
≥99%
in stock  
$11,890.00   $8,323.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FBWL
Chemical Name:
4'-C-Azidocytidine 2',3',5'-tris(2-methylpropanoate)
CAS Number:
690270-29-2
Molecular Formula:
C21H30N6O8
Molecular Weight:
494.4983
MDL Number:
MFCD18251433
SMILES:
[N-]=[N+]=N[C@]1(COC(=O)C(C)C)O[C@H]([C@@H]([C@@H]1OC(=O)C(C)C)OC(=O)C(C)C)n1ccc(nc1=O)N
Properties
Computed Properties
 
Complexity:
971  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
12  
Undefined Bond Stereocenter Count:
1  
XLogP3:
2.5  

Literature

Title: Chemical stability of 4'-azidocytidine and its prodrug balapiravir.

Journal: Drug development and industrial pharmacy 20100401

Title: Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.

Journal: Journal of medicinal chemistry 20090910

Title: Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C.

Journal: Hepatology (Baltimore, Md.) 20080801

Title: R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin.

Journal: Hepatology (Baltimore, Md.) 20080801

Title: Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability.

Journal: Drug development and industrial pharmacy 20080701

Title: The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.

Journal: Antimicrobial agents and chemotherapy 20080501

Title: Future treatment options for HCV: double, triple, what is the optimal combination?

Journal: Best practice & research. Clinical gastroenterology 20080101

Title: Nguyen NM, et al. A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. J Infect Dis. 2013 May 1;207(9):1442-1450.

Title: Nelson DR, et al. Balapiravir plus peginterferon alfa-2a (40KD)/ribavirin in a randomized trial of hepatitis C genotype 1 patients.Ann Hepatol. 2012 Jan-Feb;11(1):15-31.

Title: Yen-Liang Chen, et al. Activation of Peripheral Blood Mononuclear Cells by Dengue Virus Infection Depotentiates Balapiravir. J Virol. 2014 Feb;88(3):1740-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 690270-29-2
Tags:690270-29-2 Molecular Formula|690270-29-2 MDL|690270-29-2 SMILES|690270-29-2 4'-C-Azidocytidine 2',3',5'-tris(2-methylpropanoate)