Home Other Building Blocks 69123-90-6
69123-90-6,MFCD00868897
Catalog No.:AA00FBX7

69123-90-6 | Fiacitabine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$244.00   $171.00
- +
5mg
95%
1 week  
$454.00   $318.00
- +
10mg
95%
1 week  
$626.00   $438.00
- +
25mg
95%
1 week  
$967.00   $677.00
- +
50mg
95%
1 week  
$1,292.00   $904.00
- +
100mg
95%
1 week  
$1,715.00   $1,200.00
- +
500mg
95%
1 week  
$3,395.00   $2,376.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FBX7
Chemical Name:
Fiacitabine
CAS Number:
69123-90-6
Molecular Formula:
C9H11FIN3O4
Molecular Weight:
371.1042
MDL Number:
MFCD00868897
SMILES:
OC[C@H]1O[C@H]([C@H]([C@@H]1O)F)n1cc(I)c(nc1=O)N
Properties
Computed Properties
 
Complexity:
430  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.7  

Literature

Title: Therapeutic gene expression in transduced mesenchymal stem cells can be monitored using a reporter gene.

Journal: Nuclear medicine and biology 20121101

Title: Evaluation of F-18-labeled 5-iodocytidine (18F-FIAC) as a new potential positron emission tomography probe for herpes simplex virus type 1 thymidine kinase imaging.

Journal: Nuclear medicine and biology 20111001

Title: Radiosynthesis of F-18 labeled cytidine analog 2'-fluoro-5-iodo-l-beta-d-arabinofuranosylcytosine ([(18)F]FIAC).

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090101

Title: Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines.

Journal: Bioorganic & medicinal chemistry 20041015

Title: Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides.

Journal: Nucleosides, nucleotides & nucleic acids 20040101

Title: Structure--activity relationships of 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)pyrimidine nucleosides as anti-hepatitis B virus agents.

Journal: Journal of medicinal chemistry 19960705

Title: Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.

Journal: Antiviral research 19951201

Title: Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds.

Journal: Antimicrobial agents and chemotherapy 19950701

Title: Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19950401

Title: Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.

Journal: Antiviral research 19920701

Title: Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.

Journal: Antiviral research 19910701

Title: Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks.

Journal: Antimicrobial agents and chemotherapy 19900301

Title: Incorporation and metabolism of 2'-fluoro-5-substituted arabinosyl pyrimidines and their selective inhibition of viral DNA synthesis in herpes simplex virus type 1 (HSV-1)-infected and mock-infected Vero cells.

Journal: Antiviral research 19881201

Title: (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication.

Journal: Antimicrobial agents and chemotherapy 19881201

Title: 2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.

Journal: Journal of medicinal chemistry 19870701

Title: In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil.

Journal: Antiviral research 19870601

Title: Nucleosides. 139. Synthesis and anticytomegalovirus and antiherpes simplex virus activity of 5'-modified analogues of 2'-fluoroarabinosylpyrimidine nucleosides.

Journal: Journal of medicinal chemistry 19870101

Title: Delayed treatment with combinations of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis.

Journal: Antimicrobial agents and chemotherapy 19860901

Title: Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.

Journal: Antimicrobial agents and chemotherapy 19860301

Title: Activities of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine and its metabolites against herpes simplex virus types 1 and 2 in cell culture and in mice infected intracerebrally with herpes simplex virus type 2.

Journal: Antimicrobial agents and chemotherapy 19860101

Title: Comparative anti-herpesvirus activities of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, acyclovir, and two 2'-fluoropyrimidine nucleosides.

Journal: Antiviral research 19851001

Title: Comparative efficacy and selectivity of some nucleoside analogs against Epstein-Barr virus.

Journal: Antimicrobial agents and chemotherapy 19850601

Title: In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds.

Journal: Antiviral research 19840601

Title: Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracils.

Journal: Journal of medicinal chemistry 19840101

Title: Efficacy and selectivity of some nucleoside analogs as anti-human cytomegalovirus agents.

Journal: Antimicrobial agents and chemotherapy 19831001

Title: Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.

Journal: Antiviral research 19830901

Title: Therapeutic activities of 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and -thymine alone and in combination with acyclovir and vidarabine in mice infected intracerebrally with herpes simplex virus.

Journal: Antimicrobial agents and chemotherapy 19830701

Title: Nucleosides. 123. Synthesis of antiviral nucleosides: 5-substituted 1-(2-deoxy-2-halogeno-beta-D-arabinofuranosyl)cytosines and -uracils. Some structure-activity relationships.

Journal: Journal of medicinal chemistry 19830201

Title: Pulmonary and neurologic complications of treatment with FIAC (2'fluoro-5-iodo-aracytosine) in patients with acquired immune deficiency syndrome (AIDS).

Journal: AIDS research 19830101

Title: Inhibitory effects of antiherpesviral thymidine analogs against varicella-zoster virus.

Journal: Antimicrobial agents and chemotherapy 19820201

Title: Differential activity of potential antiviral nucleoside analogs on herpes simplex virus-induced and human cellular thymidine kinases.

Journal: Antimicrobial agents and chemotherapy 19810901

Title: Selective inhibition of herpesvirus deoxyribonucleic acid synthesis by acycloguanosine, 2'-fluoro-5-iodo-aracytosine, and (E)-5-(2-bromovinyl)-2'-deoxyuridine.

Journal: Antimicrobial agents and chemotherapy 19810501

Title: 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.

Journal: Antimicrobial agents and chemotherapy 19800501

Title: Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides.

Journal: Journal of medicinal chemistry 19790101

Title: Allaudeen HS, et al. Selective inhibition of DNA replication in herpes simplex virus infected cells by 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine. J Biol Chem. 1982 Oct 25;257(20):11879-82.

Title: Lopez C, et al. 2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent. Antimicrob Agents Chemother. 1980 May;17(5):803-6.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:69123-90-6 Molecular Formula|69123-90-6 MDL|69123-90-6 SMILES|69123-90-6 Fiacitabine