+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Fluorides 763111-47-3
763111-47-3,MFCD18251631
Catalog No.:AA00G3K2

763111-47-3 | 4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$25.00   $18.00
- +
1g
97%
in stock  
$31.00   $22.00
- +
5g
97%
in stock  
$137.00   $96.00
- +
10g
97%
in stock  
$171.00   $120.00
- +
25g
97%
in stock  
$385.00   $270.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3K2
Chemical Name:
4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one
CAS Number:
763111-47-3
Molecular Formula:
C20H19FN4O2
Molecular Weight:
366.3889
MDL Number:
MFCD18251631
SMILES:
Fc1ccc(cc1C(=O)N1CCNCC1)Cc1n[nH]c(=O)c2c1cccc2
Properties
Computed Properties
 
Complexity:
605  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
1.5  

Literature

Title: 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

Journal: Journal of medicinal chemistry 20081023

Title: Tao Huang, et al. Initial evaluation of Cu-64 labeled PARPi-DOTA PET imaging in mice with mesothelioma. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3472-3476.

Title: Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 763111-47-3
763113-22-0

763113-22-0

 1174043-16-3

1174043-16-3

 763111-49-5

763111-49-5

 2108829-86-1

2108829-86-1

 763114-04-1

763114-04-1

 1956340-97-8

1956340-97-8
Building Blocks
More >
Tags:763111-47-3 Molecular Formula|763111-47-3 MDL|763111-47-3 SMILES|763111-47-3 4-(4-Fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one |Fluorinated_Building_Blocks