Home Amines 85-87-0
85-87-0,MFCD00464815
Catalog No.:AA00G5XB

85-87-0 | pyridoxamine

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500mg
95%
1 week  
$242.00   $169.00
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1g
95%
1 week  
$333.00   $233.00
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5g
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$984.00   $689.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G5XB
Chemical Name:
pyridoxamine
CAS Number:
85-87-0
Molecular Formula:
C8H12N2O2
Molecular Weight:
168.1931
MDL Number:
MFCD00464815
SMILES:
NCc1c(CO)cnc(c1O)C
Properties
Computed Properties
 
Complexity:
143  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-1  

Literature

Title: Tobacco NUP1 transports both tobacco alkaloids and vitamin B6.

Journal: Phytochemistry 20150501

Title: Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status.

Journal: Journal of bioenergetics and biomembranes 20141001

Title: PI3Kγ activation is required for LPS-induced reactive oxygen species generation in respiratory epithelial cells.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121101

Title: Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome.

Journal: Molecular microbiology 20121001

Title: Generation of superoxide anions by a glycation reaction in conventional laboratory media.

Journal: Journal of bioscience and bioengineering 20120901

Title: Characterization of an acid phosphatase responsible for hydrolysis of pyridoxal 5'-phosphate in tobacco plants.

Journal: Plant physiology and biochemistry : PPB 20120801

Title: 2012 update on diabetic kidney disease: the expanding spectrum, novel pathogenic insights and recent clinical trials.

Journal: Minerva medica 20120801

Title: Vitamin B6 vitamer concentrations in cerebrospinal fluid differ between preterm and term newborn infants.

Journal: Pediatrics 20120701

Title: Crystal structure and substrate specificity of the thermophilic serine:pyruvate aminotransferase from Sulfolobus solfataricus.

Journal: Acta crystallographica. Section D, Biological crystallography 20120701

Title: The role of vitamin B6 as an antioxidant in the presence of vitamin B2-photogenerated reactive oxygen species. A kinetic and mechanistic study.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601

Title: Update on potential drugs for the treatment of diabetic kidney disease.

Journal: Clinical therapeutics 20120601

Title: The oxidative stress may be induced by the elevated homocysteine in schizophrenic patients.

Journal: Neurochemical research 20120501

Title: Lipid glycation and protein glycation in diabetes and atherosclerosis.

Journal: Amino acids 20120401

Title: Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics.

Journal: Amino acids 20120401

Title: High- and low-spin Fe(III) complexes of various AGE inhibitors.

Journal: The journal of physical chemistry. A 20120322

Title: Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis.

Journal: Journal of hepatology 20120301

Title: Individual vitamin B6 contents in selected Japanese sushi toppings.

Journal: International journal of food sciences and nutrition 20120301

Title: Synergistic effects of telmisartan and pyridoxamine on early renal damage in spontaneously hypertensive rats.

Journal: Molecular medicine reports 20120301

Title: Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo.

Journal: Experimental & molecular medicine 20120227

Title: Mechanisms and interventions in peritoneal fibrosis.

Journal: Clinical and experimental nephrology 20120201

Title: Structure and mechanism of a cysteine sulfinate desulfinase engineered on the aspartate aminotransferase scaffold.

Journal: Biochimica et biophysica acta 20120201

Title: Advanced glycation end-products inhibition improves endothelial dysfunction in rheumatoid arthritis.

Journal: International journal of rheumatic diseases 20120201

Title: Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing.

Journal: PLoS neglected tropical diseases 20120201

Title: Abnormality in expression levels of gluconeogenesis-related genes by high-dose supplementation with pyridoxamine in mice.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20120201

Title: Quantification of vitamin B6 vitamers in human cerebrospinal fluid by ultra performance liquid chromatography-tandem mass spectrometry.

Journal: Analytica chimica acta 20120127

Title: Pyridorin in type 2 diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Pyridoxamine, advanced glycation inhibition, and diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Genes of early-onset epileptic encephalopathies: from genotype to phenotype.

Journal: Pediatric neurology 20120101

Title: Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress.

Journal: Experimental diabetes research 20120101

Title: Glycine therapy inhibits the progression of cataract in streptozotocin-induced diabetic rats.

Journal: Molecular vision 20120101

Title: Identification of a novel gene product that promotes survival of Mycobacterium smegmatis in macrophages.

Journal: PloS one 20120101

Title: F420H2-dependent degradation of aflatoxin and other furanocoumarins is widespread throughout the actinomycetales.

Journal: PloS one 20120101

Title: GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence.

Journal: PloS one 20120101

Title: All-enzymatic HPLC method for determination of individual and total contents of vitamin B(6) in foods.

Journal: Food & nutrition research 20120101

Title: Vitamin Supplement - Editorial.

Journal: Food & nutrition research 20120101

Title: Accounting for differences in the bioactivity and bioavailability of vitamers.

Journal: Food & nutrition research 20120101

Title: Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes.

Journal: International journal of vascular medicine 20120101

Title: Pseudomonas aeruginosa overrides the virulence inducing effect of opioids when it senses an abundance of phosphate.

Journal: PloS one 20120101

Title: Regenerative therapies for diabetic microangiopathy.

Journal: Experimental diabetes research 20120101

Title: Application of CZE Method in Routine Analysis for Determination of B-Complex Vitamins in Pharmaceutical and Veterinary Preparations.

Journal: International journal of analytical chemistry 20120101

Title: [Carbonyl stress-related schizophrenia--perspective on future therapy and hypotheses regarding pathophysiology of schizophrenia].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20120101

Title: [Schizophrenia and carbonyl stress].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20120101

Title: Structural and mutational studies on substrate specificity and catalysis of Salmonella typhimurium D-cysteine desulfhydrase.

Journal: PloS one 20120101

Title: Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1.

Journal: PloS one 20120101

Title: Induction of neuronal death by microglial AGE-albumin: implications for Alzheimer's disease.

Journal: PloS one 20120101

Title: Application of optical biosensors in small-molecule screening activities.

Journal: Sensors (Basel, Switzerland) 20120101

Title: Effects of Differences in Lipid A Structure on TLR4 Pro-Inflammatory Signaling and Inflammasome Activation.

Journal: Frontiers in immunology 20120101

Title: Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway.

Journal: European journal of pharmacology 20111215

Title: Interconversions of different forms of vitamin B6 in tobacco plants.

Journal: Phytochemistry 20111201

Title: Sphingosine kinase-1 pathway mediates high glucose-induced fibronectin expression in glomerular mesangial cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20111201

Title: Vitamin B(6) salvage enzymes: mechanism, structure and regulation.

Journal: Biochimica et biophysica acta 20111101

Title: Vitamin B6s inhibit oxidative stress caused by Alzheimer's disease-related Cu(II)-β-amyloid complexes-cooperative action of phospho-moiety.

Journal: Bioorganic & medicinal chemistry letters 20111101

Title: Characterization of enzymes involved in the interconversions of different forms of vitamin B(6) in tobacco leaves.

Journal: Plant physiology and biochemistry : PPB 20111101

Title: Oxidative stress and the etiology of insulin resistance and type 2 diabetes.

Journal: Free radical biology & medicine 20110901

Title: Quantitative shotgun proteomics using a uniform ¹⁵N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii.

Journal: Molecular & cellular proteomics : MCP 20110901

Title: Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.

Journal: Neurochemistry international 20110901

Title: Pyridoxamine protects protein backbone from oxidative fragmentation.

Journal: Biochemical and biophysical research communications 20110805

Title: Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110801

Title: Pyridoxine supply in human development.

Journal: Seminars in cell & developmental biology 20110801

Title: Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues.

Journal: Biochemistry 20110712

Title: Phenol group in pyridoxamine acts as a stabilizing element for its carbinolamines and Schiff bases.

Journal: Chemistry & biodiversity 20110701

Title: [Effects of telmisartan and pyridoxamine on abdominal aorta vascular remodeling in spontaneously hypertensive rats].

Journal: Zhonghua xin xue guan bing za zhi 20110701

Title: Pyridoxamine prevents age-related aortic stiffening and vascular resistance in association with reduced collagen glycation.

Journal: Experimental gerontology 20110601

Title: Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis.

Journal: Plant molecular biology 20110501

Title: The question is, my dear watson, why did the dog not bark?: the joslin 50-year medalist study.

Journal: Diabetes care 20110401

Title: Isolation and structural characterization of acrylamide-pyridoxamine adducts.

Journal: Chemical research in toxicology 20110321

Title: Müller glial dysfunction during diabetic retinopathy in rats is linked to accumulation of advanced glycation end-products and advanced lipoxidation end-products.

Journal: Diabetologia 20110301

Title: Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice.

Journal: Diabetologia 20110301

Title: Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans.

Journal: Molecular microbiology 20110301

Title: Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes.

Journal: Diabetes 20110301

Title: Glycation of the muscle-specific enolase by reactive carbonyls: effect of temperature and the protection role of carnosine, pyridoxamine and phosphatidylserine.

Journal: The protein journal 20110301

Title: Sensitive non-radioactive determination of aminotransferase stereospecificity for C-4' hydrogen transfer on the coenzyme.

Journal: Biochemical and biophysical research communications 20110225

Title: Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases.

Journal: Biotechnology and bioengineering 20110201

Title: Systemic bioavailability and pharmacokinetics of the doxylamine-pyridoxine delayed-release combination (Diclectin).

Journal: Therapeutic drug monitoring 20110201

Title: Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy.

Journal: American journal of physiology. Renal physiology 20110201

Title: KIOM-79, an Inhibitor of AGEs-Protein Cross-linking, Prevents Progression of Nephropathy in Zucker Diabetic Fatty Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Positive transcriptional control of the pyridoxal phosphate biosynthesis genes pdxST by the MocR-type regulator PdxR of Corynebacterium glutamicum ATCC 13032.

Journal: Microbiology (Reading, England) 20110101

Title: Expression, in vivo localization and phylogenetic analysis of a pyridoxine 5'-phosphate oxidase in Arabidopsis thaliana.

Journal: Plant physiology and biochemistry : PPB 20110101

Title: The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli.

Journal: BMC genomics 20110101

Title: It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase.

Journal: PloS one 20110101

Title: Comparative proteomics analysis of the root apoplasts of rice seedlings in response to hydrogen peroxide.

Journal: PloS one 20110101

Title: Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Factors in the Aorta of Zucker Diabetic Fatty Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage.

Journal: PloS one 20110101

Title: Haptenation: chemical reactivity and protein binding.

Journal: Journal of allergy 20110101

Title: Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation.

Journal: BMC genomics 20110101

Title: Update on the management of diabetic polyneuropathies.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.

Journal: Molecular vision 20110101

Title: Single-domain parvulins constitute a specific marker for recently proposed deep-branching archaeal subgroups.

Journal: Evolutionary bioinformatics online 20110101

Title: Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity.

Journal: PloS one 20110101

Title: Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid .

Journal: Biochemistry 20101214

Title: Identification of evolutionarily conserved genetic regulators of cellular aging.

Journal: Aging cell 20101201

Title: Effects of folic acid supplementation to rations differing in the concentrate to roughage ratio on ruminal fermentation, nutrient flow at the duodenum, and on serum and milk variables of dairy cows.

Journal: Archives of animal nutrition 20101201

Title: Crystal structure of glutamate-1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate.

Journal: Biochemical and biophysical research communications 20101112

Title: Identification and characterization of two families of F420 H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation.

Journal: Molecular microbiology 20101101

Title: Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane.

Journal: PLoS neglected tropical diseases 20101001

Title: Alagebrium chloride, a novel advanced glycation end-product cross linkage breaker, inhibits neointimal proliferation in a diabetic rat carotid balloon injury model.

Journal: Korean circulation journal 20101001

Title: Pyridoxamine, an inhibitor of advanced glycation end product (AGE) formation ameliorates insulin resistance in obese, type 2 diabetic mice.

Journal: Protein and peptide letters 20100901

Title: Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Journal: Molecular bioSystems 20100901

Title: Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly.

Journal: Biochemistry 20100824

Title: Modulation of amyloid beta peptide(1-42) cytotoxicity and aggregation in vitro by glucose and chondroitin sulfate.

Journal: Current Alzheimer research 20100801

Title: Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients.

Journal: Intensive care medicine 20100801

Title: Seizures and paroxysmal events: symptoms pointing to the diagnosis of pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency.

Journal: Developmental medicine and child neurology 20100701

Title: Infusion fluids contain harmful glucose degradation products.

Journal: Intensive care medicine 20100701

Title: Pyridoxine-dependent epilepsy and pyridoxine phosphate oxidase deficiency: unique clinical symptoms and non-specific EEG characteristics.

Journal: Developmental medicine and child neurology 20100701

Title: Recent insights into pre- and postnatal pyridoxal phosphate deficiency, a treatable metabolic encephalopathy.

Journal: Developmental medicine and child neurology 20100701

Title: Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics.

Journal: Biochemistry 20100622

Title: Comparisons of uptake and cell surface binding among pyridoxal, pyridoxine, and pyridoxamine in RAW264.7 cells.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20100601

Title: Potential new therapeutic agents for diabetic kidney disease.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100501

Title: DFT studies on Schiff base formation of vitamin B6 analogues. Reaction between a pyridoxamine-analogue and carbonyl compounds.

Journal: The journal of physical chemistry. A 20100408

Title: Esmond E. Snell--the pathfinder of B vitamins and cofactors.

Journal: Journal of biochemistry 20100401

Title: Water-Soluble alpha,beta-unsaturated aldehydes of cigarette smoke induce carbonylation of human serum albumin.

Journal: Antioxidants & redox signaling 20100301

Title: 2-Deoxy-D-ribose induces cellular damage by increasing oxidative stress and protein glycation in a pancreatic beta-cell line.

Journal: Metabolism: clinical and experimental 20100301

Title: Traditional reactive carbonyl scavengers do not prevent the carbonylation of brain proteins induced by acute glutathione depletion.

Journal: Free radical research 20100301

Title: Imitating prebiotic homochirality on Earth.

Journal: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20100201

Title: Involvement of advanced glycation end-products, pentosidine and N(epsilon)-(carboxymethyl)lysine, in doxorubicin-induced cardiomyopathy in rats.

Journal: Toxicology 20100131

Title: Role of pyridoxamine in the formation of the Amadori/Heyns compounds and aggregates during the glycation of beta-lactoglobulin with galactose and tagatose.

Journal: Journal of agricultural and food chemistry 20100113

Title: Vitamin B6 metabolism in chronic kidney disease--relation to transsulfuration, advanced glycation and cardiovascular disease.

Journal: Nephron. Clinical practice 20100101

Title: Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm).

Journal: The Journal of biological chemistry 20100101

Title: Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells.

Journal: Biochemical and biophysical research communications 20100101

Title: Photophysics and photochemical studies of the vitamin B6 group and related derivatives.

Journal: Photochemistry and photobiology 20100101

Title: Ginkgo biloba and ginkgotoxin.

Journal: Journal of natural products 20100101

Title: Characterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis.

Journal: Chemical research in toxicology 20100101

Title: Orthophosphate binding at the dimer interface of Corynebacterium callunae starch phosphorylase: mutational analysis of its role for activity and stability of the enzyme.

Journal: BMC biochemistry 20100101

Title: [Drugs and the mechanism for reversing the tolerance of flurazepan in rats].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100101

Title: The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions.

Journal: PloS one 20100101

Title: Peritoneal inflammation after twenty-week exposure to dialysis solution: effect of solution versus catheter-foreign body reaction.

Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101

Title: The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments.

Journal: PloS one 20100101

Title: Accumulation of advanced glycation end (AGEs) products in intensive care patients: an observational, prospective study.

Journal: BMC clinical pathology 20100101

Title: Development of simultaneous enzymatic assay method for all six individual vitamin B6 forms and pyridoxine-beta-glucoside.

Journal: Journal of nutritional science and vitaminology 20100101

Title: Body weight control by a high-carbohydrate/low-fat diet slows the progression of diabetic kidney damage in an obese, hypertensive, type 2 diabetic rat model.

Journal: Journal of obesity 20100101

Title: Advanced glycation end products, oxidative stress and diabetic nephropathy.

Journal: Oxidative medicine and cellular longevity 20100101

Title: Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats.

Journal: Molecular vision 20100101

Title: Boolean versus ranked querying for biomedical systematic reviews.

Journal: BMC medical informatics and decision making 20100101

Title: A multi-level study of recombinant Pichia pastoris in different oxygen conditions.

Journal: BMC systems biology 20100101

Title: Limited joint mobility in diabetes and ageing: recent advances in pathogenesis and therapy.

Journal: International journal of immunopathology and pharmacology 20100101

Title: A novel biosensor for evaluation of apoptotic or necrotic effects of nitrogen dioxide during acute pancreatitis in rat.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Exercise therapy in type 2 diabetes.

Journal: Acta diabetologica 20091201

Title: Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder.

Journal: The Journal of biological chemistry 20091106

Title: High rates and substrate selectivities in water by polyvinylimidazoles as transaminase enzyme mimics with hydrophobically bound pyridoxamine derivatives as coenzyme mimics.

Journal: Journal of the American Chemical Society 20091104

Title: Dendrimers in solution can have their remote catalytic groups folded back into the core: enantioselective transaminations by dendritic enzyme mimics-II.

Journal: Bioorganic & medicinal chemistry letters 20091001

Title: Application of the high-performance liquid chromatography method with coulometric detection for determination of vitamin B(6) in human plasma and serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Title: Pyridoxamine protects intestinal epithelium from ionizing radiation-induced apoptosis.

Journal: Free radical biology & medicine 20090915

Title: Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products.

Journal: Journal of agricultural and food chemistry 20090909

Title: Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration.

Journal: Molecular & cellular proteomics : MCP 20090801

Title: Equivalence of protein inventories obtained from formalin-fixed paraffin-embedded and frozen tissue in multidimensional liquid chromatography-tandem mass spectrometry shotgun proteomic analysis.

Journal: Molecular & cellular proteomics : MCP 20090801

Title: Prevention of arterial stiffening by pyridoxamine in diabetes is associated with inhibition of the pathogenic glycation on aortic collagen.

Journal: British journal of pharmacology 20090801

Title: Vitamin B6 dependent seizures.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20090801

Title: Inhibition of 7,8-diaminopelargonic acid aminotransferase from Mycobacterium tuberculosis by chiral and achiral anologs of its substrate: biological implications.

Journal: Biochimie 20090701

Title: Effects of pyridoxamine (K-163) on glucose intolerance and obesity in high-fat diet C57BL/6J mice.

Journal: Metabolism: clinical and experimental 20090701

Title: Vitamin B6 compounds are capable of reducing the superoxide radical and lipid peroxide levels induced by H2O2 in vascular endothelial cells in culture.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20090701

Title: Cloning and characterization of a pyridoxine 5'-phosphate oxidase from silkworm, Bombyx mori.

Journal: Insect molecular biology 20090601

Title: Influence of antivitamins ginkgotoxin 5'-phosphate and deoxypyridoxine 5'-phosphate on human pyridoxine 5'-phosphate oxidase.

Journal: Planta medica 20090501

Title: Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20090501

Title: Metabolic interactions of AGE inhibitor pyridoxamine and antioxidant alpha-lipoic acid following 22 weeks of treatment in obese Zucker rats.

Journal: Life sciences 20090410

Title: Low concentrations of reactive gamma-ketoaldehydes prime thromboxane-dependent human platelet aggregation via p38-MAPK activation.

Journal: Biochimica et biophysica acta 20090401

Title: Enhanced pyridoxal 5'-phosphate synthetic enzyme immunoreactivities do not contribute to GABAergic inhibition in the rat hippocampus following pilocarpine-induced status epilepticus.

Journal: Neuroscience 20090331

Title: Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation.

Journal: The Journal of biological chemistry 20090327

Title: Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes.

Journal: Chemico-biological interactions 20090316

Title: N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.

Journal: Bioorganic & medicinal chemistry 20090315

Title: A comparative study of the chemical reactivity of pyridoxamine, Ac-Phe-Lys and Ac-Cys with various glycating carbonyl compounds.

Journal: Amino acids 20090301

Title: Novel therapies of diabetic nephropathy.

Journal: Current opinion in nephrology and hypertension 20090301

Title: Effect of pyridoxamine on acrylamide formation in a glucose/asparagine model system.

Journal: Journal of agricultural and food chemistry 20090211

Title: Unexpected isomeric equilibrium in pyridoxamine Schiff bases.

Journal: Bioorganic chemistry 20090201

Title: Pleiotropic effect of pyridoxamine on diabetic complications via CD36 expression in KK-Ay/Ta mice.

Journal: Diabetes research and clinical practice 20090201

Title: Pyridoxine 5'-phosphate oxidase, not pyridoxal kinase, involves in long-term potentiation induction in the rat dentate gyrus.

Journal: Hippocampus 20090101

Title: Oxidative stress mediates protein kinase C activation and advanced glycation end product formation in a mesangial cell model of diabetes and high protein diet.

Journal: American journal of nephrology 20090101

Title: The Staphylococcus aureus response to unsaturated long chain free fatty acids: survival mechanisms and virulence implications.

Journal: PloS one 20090101

Title: Poisoning pyridoxal 5-phosphate-dependent enzymes: a new strategy to target the malaria parasite Plasmodium falciparum.

Journal: PloS one 20090101

Title: Characterisation of porin genes from Mycobacterium fortuitum and their impact on growth.

Journal: BMC microbiology 20090101

Title: Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells.

Journal: BMC cell biology 20090101

Title: Enantioselective reductive amination of alpha-keto acids by papain-based semisynthetic enzyme.

Journal: Biochemistry. Biokhimiia 20090101

Title: Attenuating action of taurine and labetalol on cardiovascular alterations by pyridoxal-isoproterenol, a vitamin-drug interaction with cardiopathologic significance.

Journal: Advances in experimental medicine and biology 20090101

Title: Increased isolevuglandin-modified proteins in glaucomatous astrocytes.

Journal: Molecular vision 20090101

Title: Effects of new peritoneal dialysis solutions, pyridoxamine and AT1 receptor blocker, on TGF-beta1 and VEGF expression in rat peritoneal mesothelial cells.

Journal: American journal of nephrology 20090101

Title: Advanced glycation endproducts in sepsis and mechanical ventilation: extra or leading man?

Journal: Critical care (London, England) 20090101

Title: Advanced glycation of the Arg-Gly-Asp (RGD) tripeptide motif modulates retinal microvascular endothelial cell dysfunction.

Journal: Molecular vision 20090101

Title: The B6 database: a tool for the description and classification of vitamin B6-dependent enzymatic activities and of the corresponding protein families.

Journal: BMC bioinformatics 20090101

Title: Transcriptional response of the model planctomycete Rhodopirellula baltica SH1(T) to changing environmental conditions.

Journal: BMC genomics 20090101

Title: Conformational changes and loose packing promote E. coli Tryptophanase cold lability.

Journal: BMC structural biology 20090101

Title: Vitamin B6 deficient plants display increased sensitivity to high light and photo-oxidative stress.

Journal: BMC plant biology 20090101

Title: Vitamin B12-impaired metabolism produces apoptosis and Parkinson phenotype in rats expressing the transcobalamin-oleosin chimera in substantia nigra.

Journal: PloS one 20090101

Title: Effect of vitamin B(6) deficiency on antioxidative status in rats with exercise-induced oxidative stress.

Journal: Nutrition research and practice 20090101

Title: [Molecular biological approach to understanding mental disorders].

Journal: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20090101

Title: Pyridoxal phosphate-dependent neonatal epileptic encephalopathy.

Journal: BMJ case reports 20090101

Title: Inhibition of crystallin ascorbylation by nucleophilic compounds in the hSVCT2 mouse model of lenticular aging.

Journal: Investigative ophthalmology & visual science 20081101

Title: Interactions of the advanced glycation end product inhibitor pyridoxamine and the antioxidant alpha-lipoic acid on insulin resistance in the obese Zucker rat.

Journal: Metabolism: clinical and experimental 20081001

Title: Theoretical studies on pyridoxal 5'-phosphate-dependent transamination of alpha-amino acids.

Journal: Journal of computational chemistry 20080901

Title: PNPO deficiency: an under diagnosed inborn error of pyridoxine metabolism.

Journal: Molecular genetics and metabolism 20080801

Title: Insights into the mechanism of oxidative deamination catalyzed by DOPA decarboxylase.

Journal: Biochemistry 20080708

Title: Differential changes in pyridoxine 5'-phosphate oxidase immunoreactivity and protein levels in the somatosensory cortex and striatum of the ischemic gerbil brain.

Journal: Neurochemical research 20080701

Title: 13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase.

Journal: Nature chemical biology 20080701

Title: Structure and mutagenic conversion of E1 dehydrase: at the crossroads of dehydration, amino transfer, and epimerization.

Journal: Biochemistry 20080617

Title: Pyridoxal 5'-phosphate values in cerebrospinal fluid: reference values and diagnosis of PNPO deficiency in paediatric patients.

Journal: Molecular genetics and metabolism 20080601

Title: Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I.

Journal: Diabetologia 20080601

Title: Pyridoxine induced neuropathy by subcutaneous administration in dogs.

Journal: Journal of veterinary science 20080601

Title: Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum.

Journal: Acta crystallographica. Section D, Biological crystallography 20080601

Title: Neurodegenerative diseases of the retina and potential for protection and recovery.

Journal: Current neuropharmacology 20080601

Title: The pyridoxamine action on Amadori compounds: A reexamination of its scavenging capacity and chelating effect.

Journal: Bioorganic & medicinal chemistry 20080515

Title: Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

Title: In vitro characterization of the enzymes involved in TDP-D-forosamine biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa.

Journal: Journal of the American Chemical Society 20080409

Title: Some natural compounds enhance N epsilon-(carboxymethyl)lysine formation.

Journal: Annals of the New York Academy of Sciences 20080401

Title: Can tryptophan oxidation lead to lower tryptophan level in diabetes? A commentary on 'Propagation of protein glycation damage involves modification of tryptophan residues via reactive oxygen species: inhibition by pyridoxamine'.

Journal: Free radical biology & medicine 20080401

Title: Propagation of protein glycation damage involves modification of tryptophan residues via reactive oxygen species: inhibition by pyridoxamine.

Journal: Free radical biology & medicine 20080401

Title: N-methylpyridoxamine: novel canine vitamin B6 urine metabolite.

Journal: Bioorganic & medicinal chemistry letters 20080315

Title: Novel approaches targeted toward oxidative stress for the treatment of chronic kidney disease.

Journal: Current opinion in nephrology and hypertension 20080301

Title: Pyridoxal phosphate-dependent neonatal epileptic encephalopathy.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20080301

Title: Renoprotective effects of the AGE-inhibitor pyridoxamine in experimental chronic allograft nephropathy in rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201

Title: Energy metabolism, altered proteins, sirtuins and ageing: converging mechanisms?

Journal: Biogerontology 20080201

Title: A new fatal case of pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency.

Journal: Molecular genetics and metabolism 20080201

Title: Determination of individual vitamin B(6) compounds based on enzymatic conversion to 4-pyridoxolactone.

Journal: Journal of nutritional science and vitaminology 20080201

Title: Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine.

Journal: Biochemistry 20080122

Title: Crystal structure of pyridoxamine-pyruvate aminotransferase from Mesorhizobium loti MAFF303099.

Journal: The Journal of biological chemistry 20080111

Title: Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics.

Journal: BMC plant biology 20080101

Title: Modulation of protein function by isoketals and levuglandins.

Journal: Sub-cellular biochemistry 20080101

Title: The clinical relevance of assessing advanced glycation endproducts accumulation in diabetes.

Journal: Cardiovascular diabetology 20080101

Title: [Chronic transplant nephropathy].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20080101

Title: Adverse renal effects of the AGE inhibitor pyridoxamine in combination with ACEi in non-diabetic adriamycin-induced renal damage in rats.

Journal: Kidney & blood pressure research 20080101

Title: Enantiomers of 4-amino-3-fluorobutanoic acid as substrates for gamma-aminobutyric acid aminotransferase. Conformational probes for GABA binding.

Journal: Biochemistry 20071204

Title: Association between PNPO and schizophrenia in the Japanese population.

Journal: Schizophrenia research 20071201

Title: Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications.

Journal: Vascular health and risk management 20071201

Title: Reversed-phase high-performance liquid chromatography method with coulometric electrochemical and ultraviolet detection for the quantification of vitamins B(1) (thiamine), B(6) (pyridoxamine, pyridoxal and pyridoxine) and B(12) in animal and plant foods.

Journal: Journal of chromatography. A 20071130

Title: Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway.

Journal: Plant physiology 20071101

Title: DNA damage during glycation of lysine by methylglyoxal: assessment of vitamins in preventing damage.

Journal: Amino acids 20071101

Title: Potential role of isoketals formed via the isoprostane pathway of lipid peroxidation in ischemic arrhythmias.

Journal: Journal of cardiovascular pharmacology 20071101

Title: Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation.

Journal: Protein science : a publication of the Protein Society 20071001

Title: Isolation and characterization of bacteria capable of producing pyridoxamine (PM) and pyridoxamine 5'-phosphate (PMP), vitamin B6 compounds.

Journal: The Journal of general and applied microbiology 20071001

Title: A survey of bovine colostrum composition and colostrum management practices on Pennsylvania dairy farms.

Journal: Journal of dairy science 20070901

Title: Ability of poly-L-arginine to enhance drug absorption into aqueous humor and vitreous body after instillation in rabbits.

Journal: Biological & pharmaceutical bulletin 20070901

Title: Pyridoxal phosphate prevents progression of diabetic nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801

Title: Treatable neonatal epilepsy.

Journal: Archives of disease in childhood 20070801

Title: A screen for suppressors of gross chromosomal rearrangements identifies a conserved role for PLP in preventing DNA lesions.

Journal: PLoS genetics 20070801

Title: Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors.

Journal: Diabetes 20070701

Title: Vitamin B biosynthesis in plants.

Journal: Phytochemistry 20070701

Title: Cofactor-directed reversible denaturation pathways: the cofactor-stabilized Escherichia coli aspartate aminotransferase homodimer unfolds through a pathway that differs from that of the apoenzyme.

Journal: Biochemistry 20070515

Title: Advanced glycation endproducts: what is their relevance to diabetic complications?

Journal: Diabetes, obesity & metabolism 20070501

Title: Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts.

Journal: European journal of pharmacology 20070430

Title: Vitamin B6 suppresses apoptosis of NM-1 bovine endothelial cells induced by homocysteine and copper.

Journal: Biochimica et biophysica acta 20070401

Title: Simultaneous fluorometric resolution of pyridoxal, pyridoxamine and 4-pyridoxic acid using chemometric methods.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070401

Title: Identification of a pyridoxine (pyridoxamine) 5'-phosphate oxidase from Arabidopsis thaliana.

Journal: FEBS letters 20070206

Title: Pyridoxal 5'-phosphate may be curative in early-onset epileptic encephalopathy.

Journal: Journal of inherited metabolic disease 20070201

Title: Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.

Journal: Metabolism: clinical and experimental 20070201

Title: Vitamin B6 (pyridoxamine) supplementation and complications of diabetes.

Journal: Metabolism: clinical and experimental 20070201

Title: The human pyridoxal kinase, a plausible target for ginkgotoxin from Ginkgo biloba.

Journal: The FEBS journal 20070201

Title: Pyridoxal phosphate dependency, a newly recognized treatable catastrophic epileptic encephalopathy.

Journal: Journal of inherited metabolic disease 20070201

Title: A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days.

Journal: British journal of cancer 20070115

Title: Association of genetic polymorphisms of ACADSB and COMT with human hypertension.

Journal: Journal of hypertension 20070101

Title: A phylogenomic analysis of the Actinomycetales mce operons.

Journal: BMC genomics 20070101

Title: A possible involvement of crosstalk between advanced glycation end products (AGEs) and asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor in accelerated atherosclerosis in diabetes.

Journal: Medical hypotheses 20070101

Title: Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes.

Journal: Experimental diabetes research 20070101

Title: Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation.

Journal: Arthritis research & therapy 20070101

Title: Redox stress proteins are involved in adaptation response of the hyperthermoacidophilic archaeon Sulfolobus solfataricus to nickel challenge.

Journal: Microbial cell factories 20070101

Title: Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy.

Journal: American journal of nephrology 20070101

Title: Vitamin B6 related epilepsy during childhood.

Journal: Chang Gung medical journal 20070101

Title: The polyol pathway as a mechanism for diabetic retinopathy: attractive, elusive, and resilient.

Journal: Experimental diabetes research 20070101

Title: Potent radical-scavenging activities of thiamin and thiamin diphosphate.

Journal: Journal of clinical biochemistry and nutrition 20070101

Title: Pyridoxamine analogues scavenge lipid-derived gamma-ketoaldehydes and protect against H2O2-mediated cytotoxicity.

Journal: Biochemistry 20061226

Title: Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis.

Journal: The Journal of biological chemistry 20061222

Title: Mitochondrial function and toxicity: role of B vitamins on the one-carbon transfer pathways.

Journal: Chemico-biological interactions 20061027

Title: The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution.

Journal: Journal of molecular biology 20061020

Title: Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20061001

Title: Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis.

Journal: Proteins 20061001

Title: Water exclusion and enantioselectivity in catalysis.

Journal: Chembiochem : a European journal of chemical biology 20061001

Title: Cloning, purification and preliminary crystallographic analysis of a putative pyridoxal kinase from Bacillus subtilis.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20061001

Title: Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms.

Journal: Vascular health and risk management 20060901

Title: Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice.

Journal: Kidney international 20060801

Title: Identification of a new tetrameric pyridoxal 4-dehydrogenase as the second enzyme in the degradation pathway for pyridoxine in a nitrogen-fixing symbiotic bacterium, Mesorhizobium loti.

Journal: Archives of biochemistry and biophysics 20060801

Title: The molecular structure of Rv2074, a probable pyridoxine 5'-phosphate oxidase from Mycobacterium tuberculosis, at 1.6 angstroms resolution.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

Title: Molecular cloning, expression and characterization of pyridoxamine-pyruvate aminotransferase.

Journal: The Biochemical journal 20060615

Title: Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor.

Journal: Journal of lipid research 20060501

Title: Vitamin B6 suppresses growth of the feline mammary tumor cell line FRM.

Journal: Bioscience, biotechnology, and biochemistry 20060401

Title: Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis.

Journal: IUBMB life 20060401

Title: Crystal structure of a putative pyridoxine 5'-phosphate oxidase (Rv2607) from Mycobacterium tuberculosis.

Journal: Proteins 20060315

Title: Reactions of *NO2 with chromium(III) complexes with histamine and pyridoxamine ligands studied by the stopped-flow technique.

Journal: Analytical biochemistry 20060315

Title: Children of Latino immigrants, 4-8 years, in rural Nebraska are adequate in vitamin B-6.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060301

Title: Reaction of pyridoxamine with malondialdehyde: mechanism of inhibition of formation of advanced lipoxidation end-products.

Journal: Amino acids 20060201

Title: Tat-mediated protein transduction of human brain pyridoxine-5-P oxidase into PC12 cells.

Journal: Journal of biochemistry and molecular biology 20060131

Title: Potential utility of statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in diabetic retinopathy.

Journal: Medical hypotheses 20060101

Title: Minodronate, a nitrogen-containing bisphosphonate, is a promising remedy for treating patients with diabetic retinopathy.

Journal: Medical hypotheses 20060101

Title: Effects of poly-L-arginine on the permeation of hydrophilic compounds through surface ocular tissues.

Journal: Biological & pharmaceutical bulletin 20060101

Title: Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus.

Journal: BMC microbiology 20060101

Title: Adjuvant strategies for prevention of glomerulosclerosis.

Journal: Medical hypotheses 20060101

Title: Pyridoxamine inhibits maillard reactions in diabetic rat lenses.

Journal: Ophthalmic research 20060101

Title: Taurine attenuates pyridoxal-induced adrenomedullary catecholamine release and glycogenolysis in the rat.

Journal: Advances in experimental medicine and biology 20060101

Title: New potential agents in treating diabetic kidney disease: the fourth act.

Journal: Drugs 20060101

Title: Role of Q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase.

Journal: Biochemistry 20051220

Title: Age-dependent changes of pyridoxal phosphate synthesizing enzymes immunoreactivities and activities in the gerbil hippocampal CA1 region.

Journal: Mechanisms of ageing and development 20051201

Title: Pyridoxal phosphate inhibits the group I intron splicing.

Journal: Molecular and cellular biochemistry 20051201

Title: Purification and characterization of pyridoxine 5'-phosphate phosphatase from Sinorhizobium meliloti.

Journal: Bioscience, biotechnology, and biochemistry 20051201

Title: Structures of Mycobacterium tuberculosispyridoxine 5'-phosphate oxidase and its complexes with flavin mononucleotide and pyridoxal 5'-phosphate.

Journal: Acta crystallographica. Section D, Biological crystallography 20051101

Title: Pyridoxamine lowers oxalate excretion and kidney crystals in experimental hyperoxaluria: a potential therapy for primary hyperoxaluria.

Journal: Urological research 20051101

Title: Determinants of substrate specificity in omega-aminotransferases.

Journal: The Journal of biological chemistry 20051028

Title: Hydrophobic and electronic factors in the design of dialkylglycine decarboxylase mimics.

Journal: Bioorganic & medicinal chemistry 20051015

Title: Interactions between renin angiotensin system and advanced glycation in the kidney.

Journal: Journal of the American Society of Nephrology : JASN 20051001

Title: Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy.

Journal: Diabetes 20051001

Title: Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives.

Journal: The Journal of biological chemistry 20050902

Title: Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in uremic peritoneal dialysis rats.

Journal: Kidney international 20050901

Title: Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage.

Journal: Cellular and molecular life sciences : CMLS 20050801

Title: Multianalyte quantification of vitamin B6 and B2 species in the nanomolar range in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Clinical chemistry 20050701

Title: Inhibition of glycosylation processes: the reaction between pyridoxamine and glucose.

Journal: Chemistry & biodiversity 20050701

Title: Carbon acidity of the alpha-pyridinium carbon of a pyridoxamine analog.

Journal: Organic & biomolecular chemistry 20050607

Title: [Progress on the drug therapy for diabetic microangiopathies: AGE inhibitors].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050601

Title: The role of AGEs and AGE inhibitors in diabetic cardiovascular disease.

Journal: Current drug targets 20050601

Title: Can advanced glycation end product inhibitors modulate more than one pathway to enhance renoprotection in diabetes?

Journal: Annals of the New York Academy of Sciences 20050601

Title: Inhibitors of advanced glycation end product formation and neurovascular dysfunction in experimental diabetes.

Journal: Annals of the New York Academy of Sciences 20050601

Title: Post-Amadori AGE inhibition as a therapeutic target for diabetic complications: a rational approach to second-generation Amadorin design.

Journal: Annals of the New York Academy of Sciences 20050601

Title: Pyridoxamine: the many virtues of a maillard reaction inhibitor.

Journal: Annals of the New York Academy of Sciences 20050601

Title: High glucose-induced oxidative stress inhibits Na+/glucose cotransporter activity in renal proximal tubule cells.

Journal: American journal of physiology. Renal physiology 20050501

Title: Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme.

Journal: Acta crystallographica. Section D, Biological crystallography 20050501

Title: Neonatal epileptic encephalopathy caused by mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase.

Journal: Human molecular genetics 20050415

Title: The next generation of diabetic nephropathy therapies: an update.

Journal: Advances in chronic kidney disease 20050401

Title: Preparation of red blood cell column for capillary electrochromatography.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050401

Title: Pyridoxamine (BioStratum).

Journal: Current opinion in investigational drugs (London, England : 2000) 20050401

Title: Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology.

Journal: The Journal of biological chemistry 20050325

Title: Chiral polyamines from reduction of polypeptides: asymmetric pyridoxamine-mediated transaminations.

Journal: Bioorganic & medicinal chemistry letters 20050301

Title: Synthesis and evaluation of gadolinium complexes based on PAMAM as MRI contrast agents.

Journal: The Journal of pharmacy and pharmacology 20050301

Title: Amiloride uptake and toxicity in fission yeast are caused by the pyridoxine transporter encoded by bsu1+ (car1+).

Journal: Eukaryotic cell 20050201

Title: Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis.

Journal: FEBS letters 20050103

Title: Pyridoxamine lowers kidney crystals in experimental hyperoxaluria: a potential therapy for primary hyperoxaluria.

Journal: Kidney international 20050101

Title: Possible participation of advanced glycation end products in the pathogenesis of colorectal cancer in diabetic patients.

Journal: Medical hypotheses 20050101

Title: Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria.

Journal: Genome biology 20050101

Title: Possible participation of advanced glycation end products in the pathogenesis of osteoporosis in diabetic patients.

Journal: Medical hypotheses 20050101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20050101

Title: Inflammation causes tissue-specific depletion of vitamin B6.

Journal: Arthritis research & therapy 20050101

Title: Vitamin status and cognitive function in a long-term care population.

Journal: BMC geriatrics 20050101

Title: Biosynthesis of colitose: expression, purification, and mechanistic characterization of GDP-4-keto-6-deoxy-D-mannose-3-dehydrase (ColD) and GDP-L-colitose synthase (ColC).

Journal: Biochemistry 20041228

Title: Clinical studies of advanced glycation end product inhibitors and diabetic kidney disease.

Journal: Current diabetes reports 20041201

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20041201

Title: Crystal structure of human kynurenine aminotransferase I.

Journal: The Journal of biological chemistry 20041126

Title: Identification of an unusual [2Fe-2S]-binding motif in the CDP-6-deoxy-D-glycero-l-threo-4-hexulose-3-dehydrase from Yersinia pseudotuberculosis: implication for C-3 deoxygenation in the biosynthesis of 3,6-dideoxyhexoses.

Journal: Biochemistry 20041109

Title: Anti-angiogenic effect of pyridoxal 5'-phosphate, pyridoxal and pyridoxamine on embryoid bodies derived from mouse embryonic stem cells.

Journal: International journal of molecular medicine 20041101

Title: Structure of the phenazine biosynthesis enzyme PhzG.

Journal: Acta crystallographica. Section D, Biological crystallography 20041101

Title: Micellar liquid chromatography in clinical chemistry: application to the monitorization of B6 vitamins.

Journal: Clinica chimica acta; international journal of clinical chemistry 20041001

Title: Expression, purification, and kinetic constants for human and Escherichia coli pyridoxal kinases.

Journal: Protein expression and purification 20040801

Title: Effect of antioxidants and ACE inhibition on chemical modification of proteins and progression of nephropathy in the streptozotocin diabetic rat.

Journal: Diabetologia 20040801

Title: Mimicking enzymatic transaminations: attempts to understand and develop a catalytic asymmetric approach to chiral alpha-amino acids.

Journal: Organic & biomolecular chemistry 20040721

Title: 3-hydroxypyridine chromophores are endogenous sensitizers of photooxidative stress in human skin cells.

Journal: The Journal of biological chemistry 20040716

Title: Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator.

Journal: Journal of molecular biology 20040716

Title: A molecularly imprinted polymer-based synthetic transaminase.

Journal: Journal of the American Chemical Society 20040714

Title: Transamination reactions with multiple turnovers catalyzed by hydrophobic pyridoxamine cofactors in the presence of polyethylenimine polymers.

Journal: Journal of the American Chemical Society 20040707

Title: Photo-induced processes in vitamin B6 compounds.

Journal: Chemistry & biodiversity 20040701

Title: Integrative annotation of 21,037 human genes validated by full-length cDNA clones.

Journal: PLoS biology 20040601

Title: Genomic organization, tissue distribution and deletion mutation of human pyridoxine 5'-phosphate oxidase.

Journal: European journal of biochemistry 20040601

Title: Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase.

Journal: The Journal of biological chemistry 20040514

Title: N,N'-ethylenebis(pyridoxylideneiminato) and N,N'-ethylenebis(pyridoxylaminato): synthesis, characterization, potentiometric, spectroscopic, and DFT studies of their vanadium(IV) and vanadium(V) complexes.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040503

Title: [Carbonyl stress inhibitor towards new therapeutic interventions in diabetic nephropathy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040501

Title: Conformational changes in the reaction of pyridoxal kinase.

Journal: The Journal of biological chemistry 20040423

Title: Regulation of glomerular endothelial cell proteoglycans by glucose.

Journal: Journal of Korean medical science 20040401

Title: 4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents.

Journal: Bulletin du cancer 20040401

Title: Fluorescent assays to quantitate enzymatic activities yielding as end product an aqueous-insoluble indigo-blue dye.

Journal: Langmuir : the ACS journal of surfaces and colloids 20040316

Title: Pyridoxamine: an extremely potent scavenger of 1,4-dicarbonyls.

Journal: Chemical research in toxicology 20040301

Title: Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes.

Journal: Free radical biology & medicine 20040215

Title: Vigabatrin inhibits pyridoxine-5'-phosphate oxidase, not pyridoxal kinase in the hippocampus of seizure prone gerbils.

Journal: Neurochemistry international 20040201

Title: Disruption of the plr1+ gene encoding pyridoxal reductase of Schizosaccharomyces pombe.

Journal: Journal of biochemistry 20040201

Title: Inactivation of gamma-aminobutyric acid aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid does not proceed by the expected aromatization mechanism.

Journal: Bioorganic & medicinal chemistry letters 20040105

Title: Advanced glycation end products in clinical nephrology.

Journal: Kidney & blood pressure research 20040101

Title: American society of nephrology-36th annual meeting and renal week 2003.

Journal: IDrugs : the investigational drugs journal 20040101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20040101

Title: Advanced glycation end-products and the progress of diabetic vascular complications.

Journal: Physiological research 20040101

Title: Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments.

Journal: Diabetes/metabolism research and reviews 20040101

Title: Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis.

Journal: BMC microbiology 20040101

Title: Pyridoxine (vitamin B6) neurotoxicity: enhancement by protein-deficient diet.

Journal: Journal of applied toxicology : JAT 20040101

Title: Pyridoxal 5'-phosphate is a selective inhibitor in vivo of DNA polymerase alpha and epsilon.

Journal: Biochemical and biophysical research communications 20031226

Title: The nature of the rate-limiting steps in the refolding of the cofactor-dependent protein aspartate aminotransferase.

Journal: The Journal of biological chemistry 20031212

Title: Antioxidant activity of a Schiff base of pyridoxal and aminoguanidine.

Journal: Free radical biology & medicine 20031201

Title: Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions.

Journal: The Journal of biological chemistry 20031121

Title: Treponema denticola cystalysin catalyzes beta-desulfination of L-cysteine sulfinic acid and beta-decarboxylation of L-aspartate and oxalacetate.

Journal: FEBS letters 20031120

Title: Involvement of advanced lipooxidation end products (ALEs) and protein oxidation in the apoptotic actions of nitric oxide in insulin secreting RINm5F cells.

Journal: Biochemical pharmacology 20031115

Title: Pyridoxamine, an inhibitor of advanced glycation and lipoxidation reactions: a novel therapy for treatment of diabetic complications.

Journal: Archives of biochemistry and biophysics 20031101

Title: Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications.

Journal: The Journal of biological chemistry 20031024

Title: Catalytic enantioselective transamination of alpha-keto esters: an organic approach to enzymatic reactions.

Journal: Chemical communications (Cambridge, England) 20031021

Title: Stereochemistry of the reactions of glutamate-1-semialdehyde aminomutase with 4,5-diaminovalerate.

Journal: The Journal of biological chemistry 20031017

Title: Dendrimeric pyridoxamine enzyme mimics.

Journal: Journal of the American Chemical Society 20031008

Title: Paradoxical impact of antioxidants on post-Amadori glycoxidation: Counterintuitive increase in the yields of pentosidine and Nepsilon-carboxymethyllysine using a novel multifunctional pyridoxamine derivative.

Journal: The Journal of biological chemistry 20031003

Title: Antioxidant activities of chitobiose and chitotriose.

Journal: Biological & pharmaceutical bulletin 20030901

Title: LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats.

Journal: Diabetologia 20030801

Title: Synthesis of a novel radical trapping and carbonyl group trapping anti-AGE agent: a pyridoxamine analogue for inhibiting advanced glycation (AGE) and lipoxidation (ALE) end products.

Journal: Organic letters 20030724

Title: Origin of lipid A species modified with 4-amino-4-deoxy-L-arabinose in polymyxin-resistant mutants of Escherichia coli. An aminotransferase (ArnB) that generates UDP-4-deoxyl-L-arabinose.

Journal: The Journal of biological chemistry 20030704

Title: Inhibitory effect of pyridoxal 5'-phosphate on endothelial cell proliferation, replicative DNA polymerase and DNA topoisomerase.

Journal: International journal of molecular medicine 20030701

Title: Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase.

Journal: Protein science : a publication of the Protein Society 20030701

Title: The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats.

Journal: Kidney international 20030601

Title: Expression of a Brassic napus glutamate 1-semialdehyde aminotransferase in Escherichia coli and characterization of the recombinant protein.

Journal: Protein expression and purification 20030601

Title: Tpn1p, the plasma membrane vitamin B6 transporter of Saccharomyces cerevisiae.

Journal: The Journal of biological chemistry 20030523

Title: The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme.

Journal: Journal of the American Chemical Society 20030514

Title: Biosynthesis of Vitamin B(6) in yeast. Incorporation pattern of trioses.

Journal: The Journal of organic chemistry 20030502

Title: [The role of nonenzymatic glycation and glyco-oxidation in the development of diabetic vascular complications].

Journal: Ceskoslovenska fysiologie 20030501

Title: Inhibition of diphenolase activity of tyrosinase by vitamin b(6) compounds.

Journal: Journal of agricultural and food chemistry 20030423

Title: Treponema denticola cystalysin exhibits significant alanine racemase activity accompanied by transamination: mechanistic implications.

Journal: The Biochemical journal 20030415

Title: Structure and mechanism of Escherichia coli pyridoxine 5'-phosphate oxidase.

Journal: Biochimica et biophysica acta 20030411

Title: FT-IR study of pyridoxamine 5' phosphate.

Journal: Biochimica et biophysica acta 20030411

Title: Noncovalent binding of a reaction intermediate by a designed helix-loop-helix motif-implications for catalyst design.

Journal: Chembiochem : a European journal of chemical biology 20030404

Title: AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats.

Journal: Archives of biochemistry and biophysics 20030401

Title: Cutaneous metabolism of vitamin B-6.

Journal: The Journal of investigative dermatology 20030201

Title: Structure and function correlations between the rat liver threonine deaminase and aminotransferases.

Journal: Biochimica et biophysica acta 20030131

Title: Micellar liquid chromatography determination of B vitamins with direct injection and ultraviolet absorbance detection.

Journal: Journal of chromatography. A 20030117

Title: [Advanced glycosylation end products and chronic complications of diabetes mellitus].

Journal: Gaceta medica de Mexico 20030101

Title: The effect of vitamin B6 on cognition.

Journal: The Cochrane database of systematic reviews 20030101

Title: Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

Title: Tryptophan metabolism via transamination. In vitro aminotransferase assay using dinitrophenylhydrazine method.

Journal: Advances in experimental medicine and biology 20030101

Title: Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.

Journal: Toxicology 20021227

Title: Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes.

Journal: Free radical biology & medicine 20021215

Title: Micronutrient cofactor research with extensions to applications.

Journal: Nutrition research reviews 20021201

Title: Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme.

Journal: Structure (London, England : 1993) 20021101

Title: Hydrophobic effects on rates and substrate selectivities in polymeric transaminase mimics.

Journal: Journal of the American Chemical Society 20021030

Title: Angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors lower in vitro the formation of advanced glycation end products: biochemical mechanisms.

Journal: Journal of the American Society of Nephrology : JASN 20021001

Title: Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.

Journal: Biochemistry 20021001

Title: The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.

Journal: Diabetes 20020901

Title: Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors.

Journal: Protein engineering 20020701

Title: Chronological changes in pyridoxine-5'-phosphate oxidase immunoreactivity in the seizure-sensitive gerbil hippocampus.

Journal: Journal of neuroscience research 20020615

Title: Determination of vitamin B6 vitamers and pyridoxic acid in plasma: development and evaluation of a high-performance liquid chromatographic assay.

Journal: Analytical biochemistry 20020601

Title: Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.

Journal: Archives of biochemistry and biophysics 20020601

Title: SOS4, a pyridoxal kinase gene, is required for root hair development in Arabidopsis.

Journal: Plant physiology 20020601

Title: New approach to biomimetic transamination using bifunctional [1,3]-proton transfer catalysis in thioxanthenyl dioxide imines.

Journal: The Journal of organic chemistry 20020531

Title: A potent polymer/pyridoxamine enzyme mimic.

Journal: Journal of the American Chemical Society 20020508

Title: 2'-hydroxypyridoxol, a biosynthetic precursor of vitamins B(6) and B(1) in yeast.

Journal: Journal of the American Chemical Society 20020501

Title: Study of substrate-enzyme interaction between immobilized pyridoxamine and recombinant porcine pyridoxal kinase using surface plasmon resonance biosensor.

Journal: Biochimica et biophysica acta 20020401

Title: Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat.

Journal: Kidney international 20020301

Title: A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation.

Journal: The Journal of biological chemistry 20020201

Title: Immunohistochemical studies of brain pyridoxine-5'-phosphate oxidase.

Journal: Brain research 20020125

Title: Active site structure and stereospecificity of Escherichia coli pyridoxine-5'-phosphate oxidase.

Journal: Journal of molecular biology 20020118

Title: The human L-threonine 3-dehydrogenase gene is an expressed pseudogene.

Journal: BMC genetics 20020101

Title: Chelating activity of advanced glycation end-product inhibitors.

Journal: The Journal of biological chemistry 20011228

Title: Biosynthesis of vitamin B(6) in yeast: incorporation pattern of glucose.

Journal: Journal of the American Chemical Society 20011121

Title: Distribution of B6 vitamers in Escherichia coli as determined by enzymatic assay.

Journal: Analytical biochemistry 20011115

Title: Amides are novel protein modifications formed by physiological sugars.

Journal: The Journal of biological chemistry 20011109

Title: Pyridoxal 5'-phosphate and pyridoxal inhibit angiogenesis in serum-free rat aortic ring assay.

Journal: International journal of molecular medicine 20011101

Title: Advanced glycation end products and the progressive course of renal disease.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001

Title: Oxidative DNA damage induced by high glucose and its suppression in human umbilical vein endothelial cells.

Journal: Mutation research 20010901

Title: Specific host-guest interactions in a protein-based artificial transaminase.

Journal: Bioorganic & medicinal chemistry 20010901

Title: PLP and PMP radicals: a new paradigm in coenzyme B6 chemistry.

Journal: Bioorganic chemistry 20010801

Title: X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution.

Journal: Journal of molecular biology 20010720

Title: Dopa decarboxylase exhibits low pH half-transaminase and high pH oxidative deaminase activities toward serotonin (5-hydroxytryptamine).

Journal: Protein science : a publication of the Protein Society 20010601

Title: Vitamin B1 and B6 retention in milk after continuous-flow microwave and conventional heating at high temperatures.

Journal: Journal of food protection 20010601

Title: Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues.

Journal: Journal of nutritional science and vitaminology 20010601

Title: Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum.

Journal: Archives of biochemistry and biophysics 20010415

Title: Identification of an RNA-protein complex involved in chloroplast group II intron trans-splicing in Chlamydomonas reinhardtii.

Journal: The EMBO journal 20010402

Title: Pyridoxine and pyridoxamine inhibits superoxide radicals and prevents lipid peroxidation, protein glycosylation, and (Na+ + K+)-ATPase activity reduction in high glucose-treated human erythrocytes.

Journal: Free radical biology & medicine 20010201

Title: Structure-sweetness relationship in thaumatin: importance of lysine residues.

Journal: Chemical senses 20010201

Title: Determination of vitamin B(6) in cooked sausages.

Journal: Journal of agricultural and food chemistry 20010101

Title: Enzymes by design: chemogenetic assembly of transamination active sites containing lysine residues for covalent catalysis.

Journal: Bioconjugate chemistry 20010101

Title: AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?

Journal: Biogerontology 20010101

Title: [Antioxidant and anti-AGE therapeutics: evaluation and perspectives].

Journal: Journal de la Societe de biologie 20010101

Title: Affinity labeling of pig kidney 3,4-dihydroxyphenylalanine (Dopa) decarboxylase with N-(bromoacetyl)pyridoxamine 5'-phosphate. Modification of an active-site cysteine.

Journal: European journal of biochemistry 19911015

Title: Enzymes of vitamin B6 degradation. Purification and properties of 5-pyridoxic-acid oxygenase from Arthrobacter sp.

Journal: The Journal of biological chemistry 19861115

Title: Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32.

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Tags:85-87-0 Molecular Formula|85-87-0 MDL|85-87-0 SMILES|85-87-0 pyridoxamine