524-36-7,MFCD00012808
Catalog No.:AA00I9AR

524-36-7 | Pyridoxamine DiHCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$8.00   $6.00
- +
5g
97%
in stock  
$28.00   $19.00
- +
25g
97%
in stock  
$64.00   $45.00
- +
100g
97%
in stock  
$221.00   $155.00
- +
500g
97%
in stock  
$774.00 $542.00
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00I9AR
Chemical Name:
Pyridoxamine DiHCl
CAS Number:
524-36-7
Molecular Formula:
C8H14Cl2N2O2
Molecular Weight:
241.1150
MDL Number:
MFCD00012808
SMILES:
NCc1c(CO)cnc(c1O)C.Cl.Cl
Properties
Properties
 
BP:
460.1°C at 760 mmHg  
Form:
Solid  
MP:
224-226 °C (dec.)(lit.)  
Refractive Index:
1.6100 (estimate)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
143  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Upstream Synthesis Route

[1]Patent:WO2006/66806,2006,A1,.Locationinpatent:Page/Pagecolumn16

[2]Patent:WO2013/167991,2013,A1,.Locationinpatent:Paragraph00103;00104

[3]Patent:US2015/141468,2015,A1,.Locationinpatent:Paragraph0110;0119;0120

[1]Patent:WO2005/77902,2005,A2,.Locationinpatent:Page/Pagecolumn40-42

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

Downstream Synthesis Route

[1]JournalofOrganicChemistry,1957,vol.22,p.825

[1]PharmaceuticalChemistryJournal,1980,vol.14,p.407-409    Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,p.79-81

113-24-6    524-36-7   
C11H12N2O4(2-) 

[1]JournaloftheAmericanChemicalSociety,1986,vol.108,p.1969-1979

[1]Tetrahedron,1988,vol.44,p.7283-7292

[1]JournaloftheAmericanChemicalSociety,2003,vol.125,p.12110-12111

Literature

Title: Pyridorin in type 2 diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Pyridoxamine, advanced glycation inhibition, and diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32.

Quotation Request
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Additional Info:
SDS
Tags:524-36-7 Molecular Formula|524-36-7 MDL|524-36-7 SMILES|524-36-7 Pyridoxamine DiHCl
Catalog No.: AA00I9AR
524-36-7,MFCD00012808
524-36-7 | Pyridoxamine DiHCl
Pack Size: 1g
Purity: 97%
in stock
$8.00 $6.00
Pack Size: 5g
Purity: 97%
in stock
$28.00 $19.00
Pack Size: 25g
Purity: 97%
in stock
$64.00 $45.00
Pack Size: 100g
Purity: 97%
in stock
$221.00 $155.00
Pack Size: 500g
Purity: 97%
in stock
$774.00 $542.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00I9AR
Chemical Name: Pyridoxamine DiHCl
CAS Number: 524-36-7
Molecular Formula: C8H14Cl2N2O2
Molecular Weight: 241.1150
MDL Number: MFCD00012808
SMILES: NCc1c(CO)cnc(c1O)C.Cl.Cl
Properties
BP: 460.1°C at 760 mmHg  
Form: Solid  
MP: 224-226 °C (dec.)(lit.)  
Refractive Index: 1.6100 (estimate)  
Storage: Inert atmosphere;-20 ℃;  
Complexity: 143  
Covalently-Bonded Unit Count: 3  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 14  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 5  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
Upstream Synthesis Route
408335-89-7    524-36-7 

[1]Patent:WO2006/66806,2006,A1,.Locationinpatent:Page/Pagecolumn16

[2]Patent:WO2013/167991,2013,A1,.Locationinpatent:Paragraph00103;00104

[3]Patent:US2015/141468,2015,A1,.Locationinpatent:Paragraph0110;0119;0120

863030-57-3    524-36-7 

[1]Patent:WO2005/77902,2005,A2,.Locationinpatent:Page/Pagecolumn40-42

20905-66-2    524-36-7 

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

58-56-0    524-36-7 

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

Downstream Synthesis Route
110-86-1    524-36-7    112-13-0    104622-70-0 

[1]JournalofOrganicChemistry,1957,vol.22,p.825

20905-66-2    524-36-7 

[1]PharmaceuticalChemistryJournal,1980,vol.14,p.407-409    Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,p.79-81

113-24-6    524-36-7   
C11H12N2O4(2-) 

[1]JournaloftheAmericanChemicalSociety,1986,vol.108,p.1969-1979

524-36-7    65-22-5    122908-64-9 

[1]Tetrahedron,1988,vol.44,p.7283-7292

524-36-7    622406-07-9 

[1]JournaloftheAmericanChemicalSociety,2003,vol.125,p.12110-12111

Literature fold

Title: Pyridorin in type 2 diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN20120101

Title: Pyridoxamine, advanced glycation inhibition, and diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN20120101

Title: Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32.

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