Home Other Building Blocks 836620-48-5
836620-48-5,MFCD30718173
Catalog No.:AA00G7AP

836620-48-5 | As1842856

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$36.00   $25.00
- +
5mg
98%
in stock  
$90.00   $63.00
- +
10mg
98%
in stock  
$135.00   $95.00
- +
50mg
98%
in stock  
$316.00   $221.00
- +
100mg
≥98%(HPLC)
in stock  
$570.00   $399.00
- +
250mg
≥98%(HPLC)
in stock  
$1,211.00   $848.00
- +
500mg
≥98%(HPLC)
in stock  
$1,790.00   $1,253.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G7AP
Chemical Name:
As1842856
CAS Number:
836620-48-5
Molecular Formula:
C18H22FN3O3
Molecular Weight:
347.3840
MDL Number:
MFCD30718173
SMILES:
CCn1cc(C(=O)O)c(=O)c2c1cc(NC1CCCCC1)c(c2N)F
Properties
Computed Properties
 
Complexity:
562  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
3.6  

Literature

Title: Induction of HO-1 by carbon monoxide releasing molecule-2 attenuates thrombin-induced COX-2 expression and hypertrophy in primary human cardiomyocytes.

Journal: Toxicology and applied pharmacology 20151201

Title: Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice.

Journal: Molecular pharmacology 20101101

Title: Nagashima T, et al. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol Pharmacol. 2010 Nov;78(5):961-70.

Title: He J, et al. The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway. Biosci Rep. 2019 May 10;39(5). pii: BSR20190112.

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SDS
Tags:836620-48-5 Molecular Formula|836620-48-5 MDL|836620-48-5 SMILES|836620-48-5 As1842856