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913611-97-9,MFCD27987920
Catalog No.:AA00GR86

913611-97-9 | Brexpiprazole

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$63.00   $44.00
- +
50mg
≥98%
in stock  
$186.00   $130.00
- +
250mg
95%
in stock  
$276.00   $193.00
- +
1g
95%
in stock  
$501.00   $351.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GR86
Chemical Name:
Brexpiprazole
CAS Number:
913611-97-9
Molecular Formula:
C25H27N3O2S
Molecular Weight:
433.5658
MDL Number:
MFCD27987920
SMILES:
O=c1ccc2c([nH]1)cc(cc2)OCCCCN1CCN(CC1)c1cccc2c1ccs2
Properties
Computed Properties
 
Complexity:
636  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
4.7  

Literature

Title: The preclinical profile of brexpiprazole: what is its clinical relevance for the treatment of psychiatric disorders?

Journal: Expert review of neurotherapeutics 20151001

Title: Brexpiprazole for schizophrenia and as adjunct for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antipsychotic - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

Journal: International journal of clinical practice 20150901

Title: Brexpiprazole: First Global Approval.

Journal: Drugs 20150901

Title: Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.

Journal: The Journal of pharmacology and experimental therapeutics 20140901

Title: Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25(4):505-11.

Title: Yoshimi N, et al. Improvement of dizocilpine-induced social recognition deficits in mice by brexpiprazole, a novel serotonin-dopamine activity modulator. Eur Neuropsychopharmacol. 2015 Mar;25(3):356-64.

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SDS
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