Title: Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation.
Journal: Toxicology and applied pharmacology20180301
Title: Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment.
Journal: PloS one20140101
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters20130801
Title: Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death.
Journal: Cell death & disease20130201
Title: Abnormal histone H3K9 dimethylation but normal dimethyltransferase EHMT2 expression in cloned sheep embryos.
Journal: Theriogenology20121201
Title: Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum.
Journal: Proceedings of the National Academy of Sciences of the United States of America20121009
Title: Oncoepigenomics: making histone lysine methylation count.
Journal: European journal of medicinal chemistry20121001
Title: Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients.
Journal: AIDS (London, England)20120731
Title: Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines.
Journal: The Journal of antibiotics20120501
Title: G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120418
Title: Detecting S-adenosyl-L-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay.
Journal: Analytical biochemistry20120401
Title: An analog of BIX-01294 selectively inhibits a family of histone H3 lysine 9 Jumonji demethylases.
Journal: Journal of molecular biology20120224
Title: IVMBIX-01294, an inhibitor of the histone methyltransferase EHMT2, disrupts histone H3 lysine 9 (H3K9) dimethylation in the cleavage-stage porcine embryo.
Journal: Reproduction, fertility, and development20120101
Title: The effect of epigenetic factors on differentiation of pancreatic progenitor cells into insulin-producing cells.
Journal: Transplantation proceedings20111101
Title: Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.
Journal: Journal of medicinal chemistry20110908
Title: Epigenetic regulation of HIV-1 transcription.
Journal: Epigenomics20110801
Title: A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
Journal: Nature chemical biology20110710
Title: Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.
Journal: Journal of medicinal chemistry20100812
Title: Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.
Journal: Journal of molecular biology20100702
Title: Involvement of histone H3 lysine 9 (H3K9) methyltransferase G9a in the maintenance of HIV-1 latency and its reactivation by BIX01294.
Journal: The Journal of biological chemistry20100528
Title: A chemiluminescence-based method for identification of histone lysine methyltransferase inhibitors.
Journal: Molecular bioSystems20100510
Title: Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Journal: Science (New York, N.Y.)20100108
Title: Chromatin flow cytometry identifies changes in epigenetic cell states.
Journal: Cells, tissues, organs20100101
Title: Discovery of a 2,4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.
Journal: Journal of medicinal chemistry20091224
Title: Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.
Journal: Molecular cancer research : MCR20090601
Title: Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
Journal: Nature structural & molecular biology20090301
Title: Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds.
Journal: Cell stem cell20081106
Title: Chemical probes for histone-modifying enzymes.
Journal: Nature chemical biology20081001
Title: Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Journal: Molecular cell20070209
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry20020419
