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Title: Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20121015
Title: Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis.
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Title: Drugs: More shots on target.
Journal: Nature 20111214
Title: Novel proteasome inhibitors to overcome bortezomib resistance.
Journal: Journal of the National Cancer Institute 20110706
Title: A novel orally active proteasome inhibitor ONX 0912 triggers in vitro and in vivo cytotoxicity in multiple myeloma.
Journal: Blood 20101202
Title: Design and synthesis of an orally bioavailable and selective peptide epoxyketone proteasome inhibitor (PR-047).
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