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939981-37-0,MFCD14584417
Catalog No.:AA00GU2G

939981-37-0 | p53 and MDM2 proteins-interaction-inhibitor chiral

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
1 week  
$971.00   $680.00
- +
50mg
98%
1 week  
$2,035.00   $1,424.00
- +
100mg
98%
1 week  
$3,225.00   $2,258.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00GU2G
Chemical Name:
p53 and MDM2 proteins-interaction-inhibitor chiral
CAS Number:
939981-37-0
Molecular Formula:
C40H49Cl2N5O4
Molecular Weight:
734.7542
MDL Number:
MFCD14584417
SMILES:
CCOc1cc(ccc1C1=N[C@@]([C@@](N1C(=O)N1CCN(CC1)CC(=O)N1CCOCC1)(C)c1ccc(cc1)Cl)(C)c1ccc(cc1)Cl)C(C)(C)C
Properties
Computed Properties
 
Complexity:
1230  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
51  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
8  
XLogP3:
6.7  

Literature

Title: Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development.

Journal: ACS medicinal chemistry letters 20130509

Title: Chen R, et al. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors. Biochemistry. 2017 Jun 27;56(25):3273-3282.

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SDS
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Tags:939981-37-0 Molecular Formula|939981-37-0 MDL|939981-37-0 SMILES|939981-37-0 p53 and MDM2 proteins-interaction-inhibitor chiral
Catalog No.: AA00GU2G
939981-37-0,MFCD14584417
939981-37-0 | p53 and MDM2 proteins-interaction-inhibitor chiral
Pack Size： 10mg
Purity： 98%
1 week
$971.00 $680.00
Pack Size： 50mg
Purity： 98%
1 week
$2,035.00 $1,424.00
Pack Size： 100mg
Purity： 98%
1 week
$3,225.00 $2,258.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00GU2G
Chemical Name: p53 and MDM2 proteins-interaction-inhibitor chiral
CAS Number: 939981-37-0
Molecular Formula: C40H49Cl2N5O4
Molecular Weight: 734.7542
MDL Number: MFCD14584417
SMILES: CCOc1cc(ccc1C1=N[C@@]([C@@](N1C(=O)N1CCN(CC1)CC(=O)N1CCOCC1)(C)c1ccc(cc1)Cl)(C)c1ccc(cc1)Cl)C(C)(C)C
Properties
Complexity: 1230  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 51  
Hydrogen Bond Acceptor Count: 6  
Rotatable Bond Count: 8  
XLogP3: 6.7  
Literature fold

Title: Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development.

Journal: ACS medicinal chemistry letters20130509

Title: Chen R, et al. A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors. Biochemistry. 2017 Jun 27;56(25):3273-3282.

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