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901245-65-6,MFCD14744183
Catalog No.:AA00GU5S

901245-65-6 | Gsk-5959

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$143.00   $100.00
- +
10mg
≥98%
in stock  
$263.00   $184.00
- +
25mg
≥98%
in stock  
$545.00   $381.00
- +
50mg
DMSO
in stock  
$1,040.00   $728.00
- +
100mg
DMSO
in stock  
$1,752.00   $1,227.00
- +
500mg
DMSO
in stock  
$5,515.00   $3,861.00
- +
1000mg
DMSO
in stock  
$8,787.00   $6,151.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00GU5S
Chemical Name:
Gsk-5959
CAS Number:
901245-65-6
Molecular Formula:
C22H26N4O3
Molecular Weight:
394.4668
MDL Number:
MFCD14744183
SMILES:
COc1ccccc1C(=O)Nc1cc2c(cc1N1CCCCC1)n(c(=O)n2C)C
Properties
Computed Properties
 
Complexity:
609  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.7  

Literature

Title: 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.

Journal: ACS medicinal chemistry letters 20141113

Title: Demont EH, et al. 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. (2014) ACS Med Chem Lett. 5(11):1190-1195.

Title: Wylie S.Palmer, et al. Development of small molecule inhibitors of BRPF1 and TRIM24 bromodomains Discovery Today: Technologies Volume 19, March 2016, Pages 65-71.

Title: Srikanth Appikonda, et al. Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesionJ Biol Chem. 2018 May 11;293(19):7476-7485.

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SDS
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Tags:901245-65-6 Molecular Formula|901245-65-6 MDL|901245-65-6 SMILES|901245-65-6 Gsk-5959
Catalog No.: AA00GU5S
901245-65-6,MFCD14744183
901245-65-6 | Gsk-5959
Pack Size： 1mg
Purity： ≥98%
in stock
$46.00 $32.00
Pack Size： 5mg
Purity： ≥98%
in stock
$143.00 $100.00
Pack Size： 10mg
Purity： ≥98%
in stock
$263.00 $184.00
Pack Size： 25mg
Purity： ≥98%
in stock
$545.00 $381.00
Pack Size： 50mg
Purity： DMSO
in stock
$1,040.00 $728.00
Pack Size： 100mg
Purity： DMSO
in stock
$1,752.00 $1,227.00
Pack Size： 500mg
Purity： DMSO
in stock
$5,515.00 $3,861.00
Pack Size： 1000mg
Purity： DMSO
in stock
$8,787.00 $6,151.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00GU5S
Chemical Name: Gsk-5959
CAS Number: 901245-65-6
Molecular Formula: C22H26N4O3
Molecular Weight: 394.4668
MDL Number: MFCD14744183
SMILES: COc1ccccc1C(=O)Nc1cc2c(cc1N1CCCCC1)n(c(=O)n2C)C
Properties
Complexity: 609  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 29  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 4  
XLogP3: 2.7  
Literature fold

Title: 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain.

Journal: ACS medicinal chemistry letters20141113

Title: Demont EH, et al. 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. (2014) ACS Med Chem Lett. 5(11):1190-1195.

Title: Wylie S.Palmer, et al. Development of small molecule inhibitors of BRPF1 and TRIM24 bromodomains Discovery Today: Technologies Volume 19, March 2016, Pages 65-71.

Title: Srikanth Appikonda, et al. Cross-talk between chromatin acetylation and SUMOylation of tripartite motif-containing protein 24 (TRIM24) impacts cell adhesionJ Biol Chem. 2018 May 11;293(19):7476-7485.

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