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945526-43-2,MFCD12031591
Catalog No.:AA00H5XJ

945526-43-2 | Stem-Cell Factor/c-Kit Inhibitor, ISCK03

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$49.00   $34.00
- +
5mg
≥95%
in stock  
$156.00   $109.00
- +
10mg
≥95%
in stock  
$238.00   $166.00
- +
25mg
98%
in stock  
$484.00   $339.00
- +
50mg
98%
in stock  
$795.00   $557.00
- +
100mg
98%
in stock  
$1,320.00   $924.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00H5XJ
Chemical Name:
Stem-Cell Factor/c-Kit Inhibitor, ISCK03
CAS Number:
945526-43-2
Molecular Formula:
C19H21N3O2S
Molecular Weight:
355.4539
MDL Number:
MFCD12031591
SMILES:
O=S(=O)(c1ccc(cc1)C(C)(C)C)Nc1ccc(cc1)n1cncc1
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
522  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
3.9  

Literature

Title: Comparison of the effects of carbon ion and photon irradiation on the angiogenic response in human lung adenocarcinoma cells.

Journal: International journal of radiation oncology, biology, physics 20110801

Title: [4-t-butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs.

Journal: Biochemical pharmacology 20070901

Title: Na YJ, et al. -t-butylphenyl-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs. Biochem Pharmacol. 2007 Sep 1;74(5):780-6.

Title: Hirano T, et al. Long noncoding RNA, CCDC26, controls myeloid leukemia cell growth through regulation of KIT expression. Mol Cancer. 2015 Apr 19;14:90. doi: 10.1186/s12943-015-0364-7.

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SDS
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