[1]CurrentPatentAssignee:CHENGDUHUNDREDWAYMEDICALSCIENCEANDTECH-CN114539342,2022,ALocationinpatent:Paragraph0047-0050;0093-0104
[2]Dayal,Bishambar;Bhojawala,Jalpa;Rapole,KeshavaR.;Pramanik,BirendraN.;Ertel,NormanH.;Shefer,Sarah;Salen,Gerald[BioorganicandMedicinalChemistry,1996,vol.4,#6,p.885-890]
[1]Dayal,Bishambar;Bhojawala,Jalpa;Rapole,KeshavaR.;Pramanik,BirendraN.;Ertel,NormanH.;Shefer,Sarah;Salen,Gerald[BioorganicandMedicinalChemistry,1996,vol.4,#6,p.885-890]
[1]Patent:EP1985622,2008,A1.Locationinpatent:Page/Pagecolumn4
[1]CurrentPatentAssignee:HANGZHOUHEZEPHARMACEUTICALTECHNOLOGY-CN105330715,2016,ALocationinpatent:Paragraph0040;0041;0042
[1]CurrentPatentAssignee:HANGZHOUHEZEPHARMACEUTICALTECHNOLOGY-CN105330715,2016,ALocationinpatent:Paragraph0037;0038;0039
Title: Tauroursodeoxycholic acid attenuates gentamicin-induced cochlear hair cell death in vitro.
Journal: Toxicology letters 20180915
Title: Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease.
Journal: British journal of pharmacology 20180201
Title: Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion.
Journal: Toxicology and applied pharmacology 20180101
Title: Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation.
Journal: Chemico-biological interactions 20171225
Title: An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice.
Journal: Diabetes 20170301
Title: Endoplasmic reticulum-Golgi intermediate compartment protein 3 knockdown suppresses lung cancer through endoplasmic reticulum stress-induced autophagy.
Journal: Oncotarget 20161004
Title: Alterations in Enterohepatic Fgf15 Signaling and Changes in Bile Acid Composition Depend on Localization of Murine Intestinal Inflammation.
Journal: Inflammatory bowel diseases 20161001
Title: Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160501
Title: 2,4-dichlorophenol induces ER stress-mediated apoptosis via eIF2α dephosphorylation in vitro.
Journal: Environmental toxicology 20160201
Title: Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity.
Journal: The Journal of toxicological sciences 20160101
Title: Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling.
Journal: The FEBS journal 20150301
Title: Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum.
Journal: The Journal of pharmacology and experimental therapeutics 20141001
Title: 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice.
Journal: Molecular metabolism 20140801
Title: Ursolic acid induces autophagy in U87MG cells via ROS-dependent endoplasmic reticulum stress.
Journal: Chemico-biological interactions 20140725
Title: SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.
Journal: Cell reports 20131114
Title: The unfolded protein response and chemical chaperones reduce protein misfolding and colitis in mice.
Journal: Gastroenterology 20130501
Title: Prenatal ethanol exposure causes glucose intolerance with increased hepatic gluconeogenesis and histone deacetylases in adult rat offspring: reversal by tauroursodeoxycholic acid.
Journal: PloS one 20130101
Title: Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes.
Journal: PloS one 20130101
Title: TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury.
Journal: Journal of lipid research 20121201
Title: Monocyte chemotactic protein-induced protein (MCPIP) promotes inflammatory angiogenesis via sequential induction of oxidative stress, endoplasmic reticulum stress and autophagy.
Journal: Cellular signalling 20121101
Title: ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension.
Journal: The Journal of clinical investigation 20121101
Title: Tauroursodeoxycholic acid enhances the pre-implantation embryo development by reducing apoptosis in pigs.
Journal: Reproduction in domestic animals = Zuchthygiene 20121001
Title: Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease.
Journal: Molecular neurobiology 20121001
Title: Apolipoprotein E4 impairs macrophage efferocytosis and potentiates apoptosis by accelerating endoplasmic reticulum stress.
Journal: The Journal of biological chemistry 20120810
Title: The nephroprotective effect of tauroursodeoxycholic acid on ischaemia/reperfusion-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Journal: Basic & clinical pharmacology & toxicology 20120701
Title: Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120701
Title: A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus.
Journal: Hypertension (Dallas, Tex. : 1979) 20120701
Title: Chronic inhibition of endoplasmic reticulum stress and inflammation prevents ischaemia-induced vascular pathology in type II diabetic mice.
Journal: The Journal of pathology 20120601
Title: Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120601
Title: Chemical chaperone TUDCA preserves cone photoreceptors in a mouse model of Leber congenital amaurosis.
Journal: Investigative ophthalmology & visual science 20120601
Title: Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20120601
Title: Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr) in mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120501
Title: Lipid-induced endoplasmic reticulum stress in liver cells results in two distinct outcomes: adaptation with enhanced insulin signaling or insulin resistance.
Journal: Endocrinology 20120501
Title: Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress.
Journal: Diabetologia 20120501
Title: Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells.
Journal: Experimental cell research 20120415
Title: Effect of endoplasmic reticulum stress on porcine oocyte maturation and parthenogenetic embryonic development in vitro.
Journal: Biology of reproduction 20120401
Title: Low glucose under hypoxic conditions induces unfolded protein response and produces reactive oxygen species in lens epithelial cells.
Journal: Cell death & disease 20120401
Title: NASH is an Inflammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications.
Journal: Gut and liver 20120401
Title: Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway.
Journal: The Journal of biological chemistry 20120210
Title: Oral solubilized ursodeoxycholic acid therapy in amyotrophic lateral sclerosis: a randomized cross-over trial.
Journal: Journal of Korean medical science 20120201
Title: Inflammatory cause of metabolic syndrome via brain stress and NF-κB.
Journal: Aging 20120201
Title: Autophagy regulates inflammation in adipocytes.
Journal: Biochemical and biophysical research communications 20120106
Title: Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.
Journal: Biochemical and biophysical research communications 20120106
Title: Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20120101
Title: c-Jun regulates the stability of anti-apoptotic ΔNp63 in amyloid-β-induced apoptosis.
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: TUDCA slows retinal degeneration in two different mouse models of retinitis pigmentosa and prevents obesity in Bardet-Biedl syndrome type 1 mice.
Journal: Investigative ophthalmology & visual science 20120101
Title: Endoplasmic reticulum stress and diabetic cardiomyopathy.
Journal: Experimental diabetes research 20120101
Title: Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential.
Journal: Biochemistry research international 20120101
Title: Localization status of hepatocellular transporters in cholestasis.
Journal: Frontiers in bioscience (Landmark edition) 20120101
Title: Ursodeoxycholic acid prevents selenite-induced oxidative stress and alleviates cataract formation: In vitro and in vivo studies.
Journal: Molecular vision 20120101
Title: The role of glucosamine-induced ER stress in diabetic atherogenesis.
Journal: Experimental diabetes research 20120101
Title: Growth hormone secretagogues protect mouse cardiomyocytes from in vitro ischemia/reperfusion injury through regulation of intracellular calcium.
Journal: PloS one 20120101
Title: Regulation of chemokine and chemokine receptor expression by PPARγ in adipocytes and macrophages.
Journal: PloS one 20120101
Title: Ischemia-Reperfusion Injury and Ischemic-Type Biliary Lesions following Liver Transplantation.
Journal: Journal of transplantation 20120101
Title: Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window.
Journal: Evidence-based complementary and alternative medicine : eCAM 20120101
Title: Amelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a 'chemical chaperone' in human THP-1 monocytes.
Journal: Experimental diabetes research 20120101
Title: The evolving landscape of neurotoxicity by unconjugated bilirubin: role of glial cells and inflammation.
Journal: Frontiers in pharmacology 20120101
Title: Molecular intricacies and the role of ER stress in diabetes.
Journal: Experimental diabetes research 20120101
Title: MCP-1 induced protein promotes adipogenesis via oxidative stress, endoplasmic reticulum stress and autophagy.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Inhibition of endoplasmic reticulum stress improves mouse embryo development.
Journal: PloS one 20120101
Title: Poly(A) tail length of neurohypophysial hormones is shortened under endoplasmic reticulum stress.
Journal: Endocrinology 20111201
Title: Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111123
Title: Functional implications of lethal toxin-catalysed glucosylation of (H/K/N)Ras and Rac1 in Clostridium sordellii-associated disease.
Journal: European journal of cell biology 20111101
Title: Activation of Akt rescues endoplasmic reticulum stress-impaired murine cardiac contractile function via glycogen synthase kinase-3β-mediated suppression of mitochondrial permeation pore opening.
Journal: Antioxidants & redox signaling 20111101
Title: Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, acinar cell damage, and systemic inflammation in acute pancreatitis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20111101
Title: Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK via PKCα-mediated MKP-1 induction.
Journal: Cardiovascular research 20111101
Title: Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress.
Journal: The Journal of biological chemistry 20110916
Title: Cholesterol-derived bile acids enhance the chaperone activity of α-crystallins.
Journal: Cell stress & chaperones 20110901
Title: Functional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2).
Journal: Pharmacogenetics and genomics 20110801
Title: Tauroursodeoxycholic acid prevents retinal degeneration in transgenic P23H rats.
Journal: Investigative ophthalmology & visual science 20110701
Title: A new model for portal protein profile analysis in course of ileal intraluminal bile acid infusion using an in situ perfused rat intestine.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20110701
Title: Gene-activation mechanisms in the regression of atherosclerosis, elimination of diabetes type 2, and prevention of dementia.
Journal: Current molecular medicine 20110701
Title: Structure-function analysis of the tertiary bile acid TUDCA for the resolution of endoplasmic reticulum stress in intestinal epithelial cells.
Journal: Biochemical and biophysical research communications 20110617
Title: FFA-induced adipocyte inflammation and insulin resistance: involvement of ER stress and IKKβ pathways.
Journal: Obesity (Silver Spring, Md.) 20110301
Title: Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.
Journal: Diabetes 20110301
Title: The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.
Journal: FEBS letters 20110204
Title: Unsaturated FAs prevent palmitate-induced LOX-1 induction via inhibition of ER stress in macrophages.
Journal: Journal of lipid research 20110201
Title: Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110201
Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.
Journal: Journal of chromatography. A 20110107
Title: Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity-induced myocardial contractile dysfunction.
Journal: Journal of molecular and cellular cardiology 20110101
Title: Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration.
Journal: Journal of neurochemistry 20110101
Title: Effects of a multi-herbal extract on type 2 diabetes.
Journal: Chinese medicine 20110101
Title: [Evaluation on hepatotoxicity caused by Dioscorea bulbifera based on analysis of bile acids].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110101
Title: Amyloid-β peptide-induced secretion of endoplasmic reticulum chaperone glycoprotein GRP94.
Journal: Journal of Alzheimer's disease : JAD 20110101
Title: Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting.
Journal: PloS one 20110101
Title: Situs inversus totalis and secondary biliary cirrhosis: a case report.
Journal: Comparative hepatology 20110101
Title: Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment.
Journal: PloS one 20110101
Title: Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.
Journal: PloS one 20110101
Title: Cardiac-specific overexpression of catalase attenuates paraquat-induced myocardial geometric and contractile alteration: role of ER stress.
Journal: Free radical biology & medicine 20101215
Title: Tauroursodeoxycholate counteracts hepatocellular lysis induced by tensioactive bile salts by preventing plasma membrane-micelle transition.
Journal: Chemico-biological interactions 20101205
Title: Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells.
Journal: Journal of hepatology 20101101
Title: DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation.
Journal: Diabetes 20101101
Title: Tauroursodeoxycholic acid reduces endoplasmic reticulum stress, trypsin activation, and acinar cell apoptosis while increasing secretion in rat pancreatic acini.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20101001
Title: [Chemical constituents of bear bile].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901
Title: Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women.
Journal: Diabetes 20100801
Title: Biliary secretion of S-nitrosoglutathione is involved in the hypercholeresis induced by ursodeoxycholic acid in the normal rat.
Journal: Hepatology (Baltimore, Md.) 20100801
Title: IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.
Journal: PLoS biology 20100801
Title: Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stress.
Journal: Biochemical and biophysical research communications 20100709
Title: Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.
Journal: Hepatology (Baltimore, Md.) 20100701
Title: Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion.
Journal: Cell death & disease 20100701
Title: Ursodeoxycholic acid and tauroursodeoxycholic acid suppress choroidal neovascularization in a laser-treated rat model.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20100601
Title: Inflammation and insulin resistance: an old story with new ideas.
Journal: Korean diabetes journal 20100601
Title: Regulation of bile acid synthesis by fat-soluble vitamins A and D.
Journal: The Journal of biological chemistry 20100507
Title: Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells.
Journal: Diabetologia 20100501
Title: Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma.
Journal: International journal of cancer 20100401
Title: Reduction of AMP-activated protein kinase alpha2 increases endoplasmic reticulum stress and atherosclerosis in vivo.
Journal: Circulation 20100216
Title: Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis.
Journal: Journal of molecular and cellular cardiology 20100201
Title: Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100101
Title: Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.
Journal: Diabetes 20100101
Title: Tauroursodeoxycholic acid attenuates lipid accumulation in endoplasmic reticulum-stressed macrophages.
Journal: Journal of cardiovascular pharmacology 20100101
Title: Cellular stress responses: cell survival and cell death.
Journal: International journal of cell biology 20100101
Title: Synergy of combined doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models.
Journal: Journal of translational medicine 20100101
Title: Modulation of amyloid-β peptide-induced toxicity through inhibition of JNK nuclear localization and caspase-2 activation.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation.
Journal: BMC genomics 20100101
Title: Changes in hepatic gene expression upon oral administration of taurine-conjugated ursodeoxycholic acid in ob/ob mice.
Journal: PloS one 20100101
Title: Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase-3beta-mediated suppression of mitochondrial permeability transition.
Journal: Diabetes 20091201
Title: Prevention of Clostridium sordellii lethal toxin-induced apoptotic cell death by tauroursodeoxycholic acid.
Journal: Biochemistry 20090929
Title: Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance.
Journal: Molecular pharmacology 20090901
Title: Primary biliary cirrhosis.
Journal: Seminars in immunopathology 20090901
Title: Bile acid-induced epidermal growth factor receptor activation in quiescent rat hepatic stellate cells can trigger both proliferation and apoptosis.
Journal: The Journal of biological chemistry 20090814
Title: Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction.
Journal: Journal of molecular and cellular cardiology 20090801
Title: Apoptosis and modulation of cell cycle control by bile acids in human leukemia T cells.
Journal: Annals of the New York Academy of Sciences 20090801
Title: Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease.
Journal: World journal of gastroenterology 20090707
Title: Effect of SLCO1B1 polymorphism on the plasma concentrations of bile acids and bile acid synthesis marker in humans.
Journal: Pharmacogenetics and genomics 20090601
Title: Killing of rat basophilic leukemia cells by lethal toxin from Clostridium sordellii: critical role of phosphatidylinositide 3'-OH kinase/Akt signaling.
Journal: Biochemistry 20090303
Title: Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells.
Journal: Cellular and molecular life sciences : CMLS 20090301
Title: Endoplasmic reticulum stress plays a central role in development of leptin resistance.
Journal: Cell metabolism 20090107
Title: Effect of guggulsterone and cembranoids of Commiphora mukul on pancreatic phospholipase A(2): role in hypocholesterolemia.
Journal: Journal of natural products 20090101
Title: Bear bile: dilemma of traditional medicinal use and animal protection.
Journal: Journal of ethnobiology and ethnomedicine 20090101
Title: Ursodeoxycholic acid prevents apoptosis of mouse sensory neurons induced by cisplatin by reducing P53 accumulation.
Journal: Biochemical and biophysical research communications 20081226
Title: Dynamic localization of hepatocellular transporters in health and disease.
Journal: World journal of gastroenterology 20081128
Title: Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver.
Journal: Gut 20081001
Title: Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy.
Journal: Biochimica et biophysica acta 20080901
Title: TUDCA prevents cholestasis and canalicular damage induced by ischemia-reperfusion injury in the rat, modulating PKCalpha-ezrin pathway.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080801
Title: Cytoprotective effect of tauroursodeoxycholate on hepatocyte apoptosis induced by peroxisome proliferator-activated receptor gamma ligand.
Journal: Journal of gastroenterology and hepatology 20080701
Title: Tauroursodeoxycholic acid: relieving the pathogenesis of HFE C282Y hereditary hemochromatosis.
Journal: Hepatology (Baltimore, Md.) 20080701
Title: Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080701
Title: Tauroursodeoxycholic acid and secondary damage after spinal cord injury in rats.
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20080601
Title: Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30.
Journal: Investigative ophthalmology & visual science 20080501
Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.
Journal: Journal of medicinal chemistry 20080327
Title: Tauroursodeoxycholic acid reduces bile acid-induced apoptosis by modulation of AP-1.
Journal: Biochemical and biophysical research communications 20080227
Title: ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemical chaperones.
Journal: Human molecular genetics 20080215
Title: BAX inhibitor-1 modulates endoplasmic reticulum stress-mediated programmed cell death in Arabidopsis.
Journal: The Journal of biological chemistry 20080208
Title: Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease.
Journal: Trends in molecular medicine 20080201
Title: Estimation of cholesterol solubilization by a mixed micelle binding model in aqueous tauroursodeoxycholate:lecithin:cholesterol solutions.
Journal: Journal of pharmaceutical sciences 20080101
Title: Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
Title: Apoptosis in transgenic mice expressing the P301L mutated form of human tau.
Journal: Molecular medicine (Cambridge, Mass.) 20080101
Title: Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes.
Journal: American journal of nephrology 20080101
Title: Taurine suppresses the spread of cell death in electrically coupled RPE cells.
Journal: Molecular vision 20080101
Title: p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis.
Journal: The Journal of biological chemistry 20071123
Title: Conditional intestinal lipotoxicity in Apobec-1-/- Mttp-IKO mice: a survival advantage for mammalian intestinal apolipoprotein B mRNA editing.
Journal: The Journal of biological chemistry 20071109
Title: Chemical chaperones reduce endoplasmic reticulum stress and prevent mutant HFE aggregate formation.
Journal: The Journal of biological chemistry 20070921
Title: Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease.
Journal: Journal of lipid research 20070901
Title: Cellular osmolytes reduce lens epithelial cell death and alleviate cataract formation in galactosemic rats.
Journal: Molecular vision 20070810
Title: Defects in the leptin axis reduce abundance of the ABCG5-ABCG8 sterol transporter in liver.
Journal: The Journal of biological chemistry 20070803
Title: Tauroursodeoxycholic acid inhibits apoptosis induced by Z alpha-1 antitrypsin via inhibition of Bad.
Journal: Hepatology (Baltimore, Md.) 20070801
Title: Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: Parallel intestinal and liver injury during early cholestasis in the rat: modulation by bile salts and antioxidants.
Journal: Free radical biology & medicine 20070501
Title: A new oral formulation for the release of sodium butyrate in the ileo-cecal region and colon.
Journal: World journal of gastroenterology 20070221
Title: Human multidrug resistance protein 2 transports the therapeutic bile salt tauroursodeoxycholate.
Journal: The Journal of pharmacology and experimental therapeutics 20070201
Title: Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat.
Journal: The American journal of Chinese medicine 20070101
Title: Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms.
Journal: BMC physiology 20070101
Title: Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses.
Journal: BMC cell biology 20070101
Title: Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.
Journal: PloS one 20070101
Title: Bile acid analysis in biliary tract cancer.
Journal: Yonsei medical journal 20061231
Title: Tool from ancient pharmacopoeia prevents vision loss.
Journal: Molecular vision 20061229
Title: Therapeutic Strategies in Huntington's Disease.
Journal: Journal of clinical neurology (Seoul, Korea) 20061201
Title: [Experimental study of the permeability of Fel Ursi's in eye].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20061101
Title: Functional modulation of nuclear steroid receptors by tauroursodeoxycholic acid reduces amyloid beta-peptide-induced apoptosis.
Journal: Molecular endocrinology (Baltimore, Md.) 20061001
Title: Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060901
Title: The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice.
Journal: Journal of lipid research 20060901
Title: Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
Journal: Journal of neurochemistry 20060901
Title: Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.
Journal: Science (New York, N.Y.) 20060825
Title: Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum.
Journal: The Journal of pharmacy and pharmacology 20060801
Title: [Modulation of colon cancer cell invasiveness induced by deoxycholic acid].
Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20060701
Title: Galactosamine prevents ethinylestradiol-induced cholestasis.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601
Title: Binding studies of bile acids using the native fluorescence of the tryptophan residue Of Bax protein.
Journal: Bioscience reports 20060601
Title: Cholesterol crystals enhance and phospholipids protect against pancreatitis induced by hydrophobic bile salts: a rat model study.
Journal: Pancreas 20060501
Title: Indomethacin enhances bile salt detergent activity: relevance for NSAIDs-induced gastrointestinal mucosal injury.
Journal: Digestive diseases and sciences 20060401
Title: Bile acid transport and metabolism in rat liver slices.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060301
Title: c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model.
Journal: International journal of molecular medicine 20060301
Title: Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver.
Journal: Laboratory investigation; a journal of technical methods and pathology 20060201
Title: Ca2+-dependent cytoprotective effects of ursodeoxycholic and tauroursodeoxycholic acid on the biliary epithelium in a rat model of cholestasis and loss of bile ducts.
Journal: The American journal of pathology 20060201
Title: Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20060101
Title: Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8).
Journal: Molecular pharmaceutics 20060101
Title: Lack of interaction between tauroursodeoxycholate and ATP-binding cassette transporter isoform G2 (ABCG2).
Journal: Molecular pharmaceutics 20060101
Title: Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.
Journal: BMC cancer 20060101
Title: Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
Journal: The Journal of biological chemistry 20051230
Title: Preincubation of rat and human hepatocytes with cytoprotectants prior to cryopreservation can improve viability and function upon thawing.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20051201
Title: Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20051201
Title: 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media.
Journal: Lipids 20051001
Title: Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids.
Journal: Journal of pediatric gastroenterology and nutrition 20050801
Title: Bile acids for liver-transplanted patients.
Journal: The Cochrane database of systematic reviews 20050720
Title: Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701
Title: Activation of CREB by tauroursodeoxycholic acid protects cholangiocytes from apoptosis induced by mTOR inhibition.
Journal: Hepatology (Baltimore, Md.) 20050601
Title: Interferon-alpha-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression.
Journal: Journal of hepatology 20050601
Title: A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid.
Journal: Journal of hepatology 20050601
Title: Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20050601
Title: Biliary excretion of olmesartan, an anigotensin II receptor antagonist, in the rat.
Journal: Journal of gastroenterology and hepatology 20050501
Title: Gap junctional intercellular communication is not needed for the anticholestatic effect of tauroursodeoxycholic acid in mouse liver.
Journal: Journal of hepatology 20050401
Title: A nuclear receptor ligand down-regulates cytosolic phospholipase A2 expression to reduce bile acid-induced cyclooxygenase 2 activity in cholangiocytes: implications of anticarcinogenic action of farnesoid X receptor agonists.
Journal: Digestive diseases and sciences 20050301
Title: Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.
Journal: Biochemical pharmacology 20050201
Title: Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050101
Title: Sustaining a bioartificial liver under hypothermic conditions.
Journal: Tissue engineering 20050101
Title: Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts.
Journal: Anticancer research 20050101
Title: Hypothermic maintenance of hepatocyte spheroids.
Journal: Cell transplantation 20050101
Title: Ursodeoxycholic acid inhibits endothelin-1 production in human vascular endothelial cells.
Journal: European journal of pharmacology 20041128
Title: The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons.
Journal: The Journal of pharmacology and experimental therapeutics 20041101
Title: Biliary excretion of bile acids and organic anions in rats with dichloroethylene-induced bile canalicular injury.
Journal: Journal of gastroenterology 20041001
Title: Effects of colchicine on the maximum biliary excretion of cholephilic compounds in rats.
Journal: Journal of gastroenterology and hepatology 20040901
Title: Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells.
Journal: Journal of neurochemistry 20040801
Title: Conjugation with taurine prevents side-chain desaturation of ursodeoxycholic and beta-muricholic acids in bile fistula rats.
Journal: Fundamental & clinical pharmacology 20040801
Title: Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes.
Journal: Biochemistry 20040706
Title: Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040601
Title: Tauroursodeoxycholic acid protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways.
Journal: Hepatology (Baltimore, Md.) 20040601
Title: Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501
Title: What doesn't kill you makes you stronger: how hepatocytes survive prolonged cholestasis.
Journal: Hepatology (Baltimore, Md.) 20040401
Title: [Deoxycholic acid-induced signal transduction in HT-29 cells: role of NF-kappa B and interleukin-8].
Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20040301
Title: Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid.
Journal: Biochimica et biophysica acta 20040202
Title: Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase.
Journal: Gastroenterology 20040201
Title: Regulation of synthesis and trafficking of canalicular transporters and its alteration in acquired hepatocellular cholestasis. Experimental therapeutic strategies for its prevention.
Journal: Current medicinal chemistry 20040201
Title: A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol.
Journal: BMC medicine 20040101
Title: High-performance liquid chromatographic mass spectrometric method for the determination of ursodeoxycholic acid and its glycine and taurine conjugates in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225
Title: Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
Journal: The Journal of clinical investigation 20031201
Title: Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes.
Journal: Digestive diseases and sciences 20031201
Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101
Title: Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation.
Journal: Gastroenterology 20030901
Title: Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-kappa B activation.
Journal: Journal of hepatology 20030801
Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.
Journal: Hepatology (Baltimore, Md.) 20030801
Title: Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis.
Journal: The Journal of pharmacology and experimental therapeutics 20030701
Title: Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets.
Journal: The Journal of biological chemistry 20030516
Title: Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20030513
Title: Inhibition of ileal bile acid absorption by colestimide.
Journal: Journal of gastroenterology and hepatology 20030501
Title: Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis.
Journal: Gastroenterology 20030501
Title: [Effect of Tauroursodeoxycholic acid on cytochrome C-mediated apoptosis in HepG2 cells].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20030501
Title: 3,4-dihydroxyphenylacetaldehyde: a potential target for neuroprotective therapy in Parkinson's disease.
Journal: Current drug targets. CNS and neurological disorders 20030401
Title: Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells.
Journal: European journal of pharmacology 20030319
Title: Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria.
Journal: Biochemistry 20030318
Title: Effects of bile acids on biliary epithelial cells: proliferation, cytotoxicity, and cytokine secretion.
Journal: Life sciences 20030207
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice.
Journal: The Biochemical journal 20030201
Title: Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20030201
Title: Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats.
Journal: Journal of hepatology 20030201
Title: Hydrophilic bile salts have a cytoprotective effect against cyclosporine A-induced cholestasis through enhanced canalicular membrane fluidity and transporter activity.
Journal: Hepatology research : the official journal of the Japan Society of Hepatology 20030101
Title: Bile acids for viral hepatitis.
Journal: The Cochrane database of systematic reviews 20030101
Title: Urinary excretion of bile acids in bile duct-ligated rats.
Journal: Journal of gastroenterology 20030101
Title: Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway.
Journal: Molecular medicine (Cambridge, Mass.) 20030101
Title: Functional expression of the canalicular bile salt export pump of human liver.
Journal: Gastroenterology 20021101
Title: Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation.
Journal: Hepatology (Baltimore, Md.) 20020901
Title: Tauroursodeoxycholic acid (TUDCA) in the prevention of total parenteral nutrition-associated liver disease.
Journal: The Journal of pediatrics 20020801
Title: Effects of hydrophobic and hydrophilic bile salt mixtures on cholesterol crystallization in model biles.
Journal: Biochimica et biophysica acta 20020711
Title: Effects of bile acids on the muscle functions of guinea pig gallbladder.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20020701
Title: Hepatoprotection with tauroursodeoxycholate and beta muricholate against taurolithocholate induced cholestasis: involvement of signal transduction pathways.
Journal: Gut 20020701
Title: Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20020701
Title: Tauroursodeoxycholic acid reduces damaging effects of taurodeoxycholic acid on fundus gastric mucosa.
Journal: Archives of physiology and biochemistry 20020701
Title: Regulation of oxysterol 7alpha-hydroxylase (CYP7B1) in primary cultures of rat hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20020601
Title: Tauroursodeoxycholic acid mobilizes alpha-PKC after uptake in human HepG2 hepatoma cells.
Journal: European journal of clinical investigation 20020601
Title: Effects of high taurocholate load on activities of hepatic alcohol metabolizing enzymes.
Journal: Experimental & molecular medicine 20020531
Title: Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha.
Journal: Hepatology (Baltimore, Md.) 20020501
Title: Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner.
Journal: Gastroenterology 20020501
Title: Dapsone-induced cholestasis and impairment of bile salt output in the rat.
Journal: Biochemical pharmacology 20020415
Title: Neuroprotection by a bile acid in an acute stroke model in the rat.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401
Title: Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line.
Journal: Biochimica et biophysica acta 20020130
Title: Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease.
Journal: Cell transplantation 20020101
Title: High metabolic function of primary human and porcine hepatocytes in a polyurethane foam/spheroid culture system in plasma from patients with fulminant hepatic failure.
Journal: Cell transplantation 20020101
Title: Bile salt tauroursodeoxycholic acid modulation of Bax translocation to mitochondria protects the liver from warm ischemia-reperfusion injury in the rat.
Journal: Transplantation 20011215
Title: Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function.
Journal: The Biochemical journal 20011101
Title: Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione.
Journal: Hepatology (Baltimore, Md.) 20011101
Title: A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease.
Journal: Experimental neurology 20011001
Title: Micronuclei induction, cell cycle delay and apoptosis as markers of cellular stress caused by ursodeoxycholic acid in human lymphocytes.
Journal: Mutation research 20010822
Title: Stimulation of ATP secretion in the liver by therapeutic bile acids.
Journal: The Biochemical journal 20010815
Title: Beneficial effects of silymarin on estrogen-induced cholestasis in the rat: a study in vivo and in isolated hepatocyte couplets.
Journal: Hepatology (Baltimore, Md.) 20010801
Title: Cholesterol crystallization in model biles: effects of bile salt and phospholipid species composition.
Journal: Journal of lipid research 20010801
Title: Tauroursodesoxycholate-induced choleresis involves p38(MAPK) activation and translocation of the bile salt export pump in rats.
Journal: Gastroenterology 20010801
Title: Effect of sodium tauroursodeoxycholate on phalloidin-induced cholestasis in rats.
Journal: European journal of pharmacology 20010601
Title: Effect of bile acids on the proliferative activity and apoptosis of rat hepatocytes.
Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010601
Title: Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients.
Journal: Transplantation 20010515
Title: Tauroursodeoxycholic acid for the cytoprotection of liver grafts during cold storage: a new aspect of its anti-apoptotic properties?
Journal: Transplantation 20010515
Title: Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
Journal: Hepatology (Baltimore, Md.) 20010501
Title: Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo.
Journal: Journal of hepatology 20010401
Title: Cellular distribution of thrombomodulin as an early marker for warm ischemic liver injury in porcine liver transplantation: protective effect of prostaglandin I2 analogue and tauroursodeoxycholic acid.
Journal: Transplantation 20010327
Title: Bile acid transport and regulating functions in the human biliary epithelium.
Journal: Hepatology (Baltimore, Md.) 20010301
Title: Amyloid beta-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate.
Journal: Biochemical and biophysical research communications 20010223
Title: Effect of tauroursodeoxycholate and S-adenosyl-L-methionine on 17beta-estradiol glucuronide-induced cholestasis.
Journal: Journal of hepatology 20010201
Title: [Effects of bile acid preparations on DNA biosynthesis, apoptosis, and necrosis in hepatocytes in vitro].
Journal: Voprosy meditsinskoi khimii 20010101
Title: [Modulation by tauroursodeoxycholic acid of proliferation of the rat ischemic liver hepatocytes].
Journal: Voprosy meditsinskoi khimii 20010101
Title: Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition.
Journal: Journal of neurochemistry 20001201
Title: Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells.
Journal: The American journal of physiology 19980201
Title: Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter.
Journal: The American journal of physiology 19980101
Title: Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver.
Journal: Hepatology (Baltimore, Md.) 19971201
Title: Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats.
Journal: Scandinavian journal of gastroenterology 19970901
Title: Differential effects between tauroursodeoxycholic and taurochenodeoxycholic acids in hepatic fibrosis: an assessment by primary cultured Ito and Kupffer cells from the rat liver.
Journal: Journal of gastroenterology and hepatology 19960501
Title: Therapeutic index of taurocholate or tauroursodeoxycholate in experimental drug-induced cholestasis.
Journal: The Italian journal of gastroenterology 19950101
Title: Estradiol-17 beta-glucuronide-induced cholestasis. Effects of ursodeoxycholate-3-O-glucuronide and 3,7-disulfate.
Journal: Journal of hepatology 19930201
Title: Effects of bile salt infusion on chlorpromazine-induced cholestasis in the isolated perfused rat liver.
Journal: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19920101
Title: Drug-induced cholestasis in the perfused rat liver and its reversal by tauroursodeoxycholate: an ultrastructural study.
Journal: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19920101
Title: Effects of bile salt supplementation on biliary secretion in estrogen-treated rats.
Journal: The Journal of nutritional biochemistry 19900801
Title: Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.
Journal: Hepatology (Baltimore, Md.) 19900501
Title: Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16.
Title: Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.
