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152-95-4,MFCD01631196
Catalog No.:AA00HXUK

152-95-4 | Sophoricoside

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10mg
99+%
in stock  
$6.00   $4.00
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50mg
99+%
in stock  
$7.00   $5.00
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5g
99+%
in stock  
$19.00   $14.00
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25g
99+%
in stock  
$74.00   $52.00
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100g
99+%
in stock  
$260.00   $182.00
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500g
99+%
in stock  
$767.00   $537.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00HXUK
Chemical Name:
Sophoricoside
CAS Number:
152-95-4
Molecular Formula:
C21H20O10
Molecular Weight:
432.3775
MDL Number:
MFCD01631196
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)c2coc3c(c2=O)c(O)cc(c3)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
675  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
4  
XLogP3:
0.9  

Upstream Synthesis Route

[1]ActaChimicaAcademiaeScientiarumHungaricae,1954,vol.4,p.383,384,386

[1]ActaChimicaAcademiaeScientiarumHungaricae,1954,vol.4,p.383,384,386

Downstream Synthesis Route
5-acetoxy-7-(4-nitro-benzyloxy)-3-4-(tetra-<i>O</i>-acetyl-β-D-glucopyranosyloxy)-phenyl-chromen-4-one 
  152-95-4 

[1]ActaChimicaAcademiaeScientiarumHungaricae,1954,vol.4,p.383,384,386

629-27-6    152-95-4   
5-hydroxy-7-octyloxy-4'-(β-D-glucopyranosyloxy)isoflavone 

[1]PharmaceuticalChemistryJournal,1997,vol.31,p.120-124

[1]ChemistryofNaturalCompounds,1996,vol.32,p.535-538

[1]ChemistryofNaturalCompounds,1996,vol.32,p.535-538

152-95-4   
5,7-dihydroxy-3-4-(β-D-glucopyranosyloxy)phenylchroman-4-one 

[1]EuropeanJournalofMedicinalChemistry,2003,vol.38,p.537-545

Literature

Title: Sophoricoside fails the embryo implantation by compromising the uterine endometrial receptivity at implantation 'window' of pregnant mice.

Journal: Chemico-biological interactions 20140805

Title: Novel interleukin-5 inhibitors based on hydroxyethylaminomethyl-4H-chromen-4-one scaffold.

Journal: Bioorganic & medicinal chemistry 20121001

Title: Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.

Journal: Bioorganic & medicinal chemistry letters 20120615

Title: Biotransformation of sophoricoside in Fructus sophorae by the fungus Schizophyllum commune.

Journal: Bioresource technology 20120501

Title: Design and synthesis of novel hydroxyalkylaminomethylchromones for their IL-5 inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20100701

Title: The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5.

Journal: Bioorganic & medicinal chemistry 20100615

Title: Synthesis and evaluation of novel chromone analogs for their inhibitory activity against interleukin-5.

Journal: European journal of medicinal chemistry 20100601

Title: Estrogenic activity of a naringinase-treated extract of Sophora japonica cultivated in Egypt.

Journal: Pharmaceutical biology 20100201

Title: Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091201

Title: [Effects of sophoricoside and genistein on biological characteristics of osteoblasts].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090301

Title: The role of alkoxy group on the A ring of isoflavones in the inhibition of interleukin-5.

Journal: Archives of pharmacal research 20070801

Title: Method development for the determination of coumarin compounds by capillary electrophoresis with indirect laser-induced fluorescence detection.

Journal: Journal of chromatography. A 20070427

Title: Structural requirement of isoflavonones for the inhibitory activity of interleukin-5.

Journal: European journal of medicinal chemistry 20030501

Title: Anti-inflammatory action of legume isoflavonoid sophoricoside through inhibition on cyclooxygenase-2 activity.

Journal: Planta medica 20030501

Title: [Effect of Sophoricoside on histomorphology of bone in ovariectomized rats].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20030501

Title: Anti-inflammatory mode of isoflavone glycoside sophoricoside by inhibition of interleukin-6 and cyclooxygenase-2 in inflammatory response.

Journal: Archives of pharmacal research 20030401

Title: Kim SJ, et al. The ameliorative effect of sophoricoside on mast cell-mediated allergic inflammation in vivo and in vitro. Molecules. 2013 May 22;18(5):6113-27.

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