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25392-41-0,MFCD00467168
Catalog No.:AA00I4RT

25392-41-0 | 4-(Chloromethyl)-7-hydroxy-2h-chromen-2-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
97%
in stock  
$70.00   $49.00
- +
1g
97%
in stock  
$112.00   $78.00
- +
5g
97%
in stock  
$295.00   $206.00
- +
10g
97%
in stock  
$544.00   $381.00
- +
25g
97%
in stock  
$996.00   $697.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I4RT
Chemical Name:
4-(Chloromethyl)-7-hydroxy-2h-chromen-2-one
CAS Number:
25392-41-0
Molecular Formula:
C10H7ClO3
Molecular Weight:
210.6138
MDL Number:
MFCD00467168
SMILES:
ClCc1cc(=O)oc2c1ccc(c2)O
Properties
Properties
 
BP:
409.6°C at 760 mmHg  
Form:
Solid  
MP:
180-183°C  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.9  

Literature

Title: TGF-β of lung cancer microenvironment upregulates B7H1 and GITRL expression in dendritic cells and is associated with regulatory T cell generation.

Journal: Oncology reports 20120801

Title: Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies.

Journal: PloS one 20110101

Title: Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.

Journal: Bioorganic & medicinal chemistry letters 20100801

Title: alpha-Glucosidase inhibitory antihyperglycemic activity of substituted chromenone derivatives.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.

Journal: Journal of medicinal chemistry 20080227

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SDS
Tags:25392-41-0 Molecular Formula|25392-41-0 MDL|25392-41-0 SMILES|25392-41-0 4-(Chloromethyl)-7-hydroxy-2h-chromen-2-one