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[1]Agarwal,HiteshK.;Buckheit,KarenW.;BuckheitJr.,RobertW.;Parang,Keykavous[BioorganicandMedicinalChemistryLetters,2012,vol.22,#17,p.5451-5454]
[1]Agarwal,HiteshK.;Buckheit,KarenW.;BuckheitJr.,RobertW.;Parang,Keykavous[BioorganicandMedicinalChemistryLetters,2012,vol.22,#17,p.5451-5454]
Title: Synthesis, anti-HIV and cytostatic evaluation of 3'-deoxy-3'-fluorothymidine (FLT) pro-nucleotides.
Journal: Bioorganic & medicinal chemistry letters 20140515
Title: Tumor lesion glycolysis and tumor lesion proliferation for response prediction and prognostic differentiation in patients with advanced non-small cell lung cancer treated with erlotinib.
Journal: Clinical nuclear medicine 20121101
Title: Liquid chromatography-tandem mass spectrometry method for quantification of thymidine kinase activity in human serum by monitoring the conversion of 3'-deoxy-3'-fluorothymidine to 3'-deoxy-3'-fluorothymidine monophosphate.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015
Title: Pharmacodynamic evaluation of irinotecan therapy by FDG and FLT PET/CT imaging in a colorectal cancer xenograft model.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20121001
Title: The effects of 5-fluoruracil treatment on 3'-fluoro-3'-deoxythymidine (FLT) transport and metabolism in proliferating and non-proliferating cultures of human tumor cells.
Journal: Nuclear medicine and biology 20121001
Title: FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.
Journal: Cancer research 20121001
Title: Monitoring reversible and irreversible EGFR inhibition with erlotinib and afatinib in a patient with EGFR-mutated non-small cell lung cancer (NSCLC) using sequential [18F]fluorothymidine (FLT-)PET.
Journal: Lung cancer (Amsterdam, Netherlands) 20120901
Title: Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20120901
Title: Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120801
Title: 18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120801
Title: Effects of minocycline on endogenous neural stem cells after experimental stroke.
Journal: Neuroscience 20120726
Title: 18F-FLT PET performs better than 18F-FDG PET in differentiating malignant uterine corpus tumors from benign leiomyoma.
Journal: Annals of nuclear medicine 20120701
Title: Predictive value of early and late residual 18F-fluorodeoxyglucose and 18F-fluorothymidine uptake using different SUV measurements in patients with non-small-cell lung cancer treated with erlotinib.
Journal: European journal of nuclear medicine and molecular imaging 20120701
Title: Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120701
Title: Imaging of cellular proliferation in liver metastasis by [18F]fluorothymidine positron emission tomography: effect of therapy.
Journal: Physics in medicine and biology 20120607
Title: An evaluation of 2-deoxy-2-[18F]fluoro-D-glucose and 3'-deoxy-3'-[18F]-fluorothymidine uptake in human tumor xenograft models.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20120601
Title: High FDG and low FLT uptake in a thyroid papillary carcinoma incidentally discovered by FDG PET/CT.
Journal: Clinical nuclear medicine 20120601
Title: Simple preparation and purification of ethanol-free solutions of 3'-deoxy-3'-[18F]fluorothymidine by means of disposable solid-phase extraction cartridges.
Journal: Nuclear medicine and biology 20120501
Title: Evaluation of an automated double-synthesis module: efficiency and reliability of subsequent radiosyntheses of FHBG and FLT.
Journal: Nuclear medicine and biology 20120501
Title: Comparison of 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography (FLT PET) and FDG PET/CT for the detection and characterization of pancreatic tumours.
Journal: European journal of nuclear medicine and molecular imaging 20120501
Title: Oxygen breathing affects 3'-deoxy-3'-18F-fluorothymidine uptake in mouse models of arthritis and cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120501
Title: Double-input compartmental modeling and spectral analysis for the quantification of positron emission tomography data in oncology.
Journal: Physics in medicine and biology 20120407
Title: Study of [18F]FLT and [123I]IaraU for cellular imaging in HSV1 tk-transfected murine fibrosarcoma cells: evaluation of the tracer uptake using 5-fluoro, 5-iodo and 5-iodovinyl arabinosyl uridines as competitive probes.
Journal: Nuclear medicine and biology 20120401
Title: Monitoring early response to taxane therapy in advanced breast cancer with circulating tumor cells and [(18)F] 3´-deoxy-3´-fluorothymidine PET: a pilot study.
Journal: Biomarkers in medicine 20120401
Title: Synthesis and anti-HIV activities of glutamate and peptide conjugates of nucleoside reverse transcriptase inhibitors.
Journal: Journal of medicinal chemistry 20120322
Title: Application of a whole-body pharmacokinetic model for targeted radionuclide therapy to NM404 and FLT.
Journal: Physics in medicine and biology 20120321
Title: [(18)F]FLT-PET imaging does not always 'light up' proliferating tumor cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120301
Title: [(18)F]FLT: an imaging biomarker of tumour proliferation for assessment of tumour response to treatment.
Journal: European journal of cancer (Oxford, England : 1990) 20120301
Title: Imaging of a localized bacterial infection with endogenous thymidine kinase using radioisotope-labeled nucleosides.
Journal: International journal of medical microbiology : IJMM 20120301
Title: PET imaging of tumor growth: not as easy as it looks.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120301
Title: 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120301
Title: Synthesis and anti-HIV activities of suramin conjugates of 3'-fluoro- 2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20120301
Title: 3'-deoxy-3'-18F-fluorothymidine PET and MRI for early survival predictions in patients with recurrent malignant glioma treated with bevacizumab.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120101
Title: 18F-FLT and 125I-IdUrd uptake increase in human tumour cell lines induced by the thymidylate synthase inhibitor FdUrd.
Journal: Nuklearmedizin. Nuclear medicine 20120101
Title: Usefulness of FDG, MET and FLT-PET studies for the management of human gliomas.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111215
Title: [18F]-3'Deoxy-3'-fluorothymidine positron emission tomography and breast cancer response to docetaxel.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111215
Title: Pharmacodynamic study using FLT PET/CT in patients with renal cell cancer and other solid malignancies treated with sunitinib malate.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111215
Title: Quantitative analysis of response to treatment with erlotinib in advanced non-small cell lung cancer using 18F-FDG and 3'-deoxy-3'-18F-fluorothymidine PET.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111201
Title: A pilot study to evaluate 3'-deoxy-3'-18F-fluorothymidine pet for initial and early response imaging in mantle cell lymphoma.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111201
Title: 3'-deoxy-3'-[¹⁸F]fluorothymidine PET quantification of bone marrow response to radiation dose.
Journal: International journal of radiation oncology, biology, physics 20111101
Title: Advances in PET imaging of brain tumors: a referring physician's perspective.
Journal: Current opinion in oncology 20111101
Title: Discriminant analysis of ¹⁸F-fluorothymidine kinetic parameters to predict survival in patients with recurrent high-grade glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111015
Title: Monitoring cellular accumulation of 3'-deoxy-3'-fluorothymidine (FLT) and its monophosphate metabolite (FLT-MP) by LC-MS/MS as a measure of cell proliferation in vitro.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111015
Title: Thiated derivatives of 2',3'-dideoxy-3'-fluorothymidine: synthesis, in vitro anti-HIV-1 activity and interaction with recombinant drug resistant HIV-1 reverse transcriptase forms.
Journal: Antiviral research 20111001
Title: Effects of image characteristics on performance of tumor delineation methods: a test-retest assessment.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111001
Title: Assessment of PET tracer uptake in hormone-independent and hormone-dependent xenograft prostate cancer mouse models.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111001
Title: Comprehensive approach to coregistration of autoradiography and microscopy images acquired from a set of sequential tissue sections.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20111001
Title: The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3'-fluoro-3'-deoxythymidine in human B-lymphoblast cells.
Journal: Nuclear medicine and biology 20111001
Title: 18F-fluorothymidine PET/CT as an early predictor of tumor response to treatment with cetuximab in human lung cancer xenografts.
Journal: Oncology reports 20110901
Title: Gastric cancer growth control by BEZ235 in vivo does not correlate with PI3K/mTOR target inhibition but with [18F]FLT uptake.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110815
Title: Early assessment of tumor response to JAC106, an anti-tubulin agent, by 3'-deoxy-3'-[¹⁸F]fluorothymidine in preclinical tumor models.
Journal: European journal of nuclear medicine and molecular imaging 20110801
Title: Differential (18)F-FDG and 3'-deoxy-3'-(18)F-fluorothymidine PET responses to pharmacologic inhibition of the c-MET receptor in preclinical tumor models.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110801
Title: [18F]FLT PET for non-invasive monitoring of early response to gene therapy in experimental gliomas.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110601
Title: Uptake decrease of proliferative PET tracer 18FLT in bone marrow after carbon ion therapy in lung cancer.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110601
Title: A dual radiologic contrast agent protocol for 18F-FDG and 18F-FLT PET/CT imaging of mice bearing abdominal tumors.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110601
Title: Correlation of 18F-FLT uptake with equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in gastrointestinal cancer.
Journal: Nuclear medicine communications 20110601
Title: SNM clinical trials network validates 100th scanner.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110601
Title: Quantitative analysis of thymidine kinase 1 and 5'(3')-deoxyribonucleotidase mRNA expression: the role of fluorothymidine uptake.
Journal: Anticancer research 20110601
Title: Single scan parameterization of space-variant point spread functions in image space via a printed array: the impact for two PET/CT scanners.
Journal: Physics in medicine and biology 20110521
Title: Novel PET biomarkers for breast cancer imaging.
Journal: Nuclear medicine communications 20110501
Title: PET/CT with 3'-deoxy-3'-[18F]fluorothymidine for lung cancer patients receiving carbon-ion radiotherapy.
Journal: Nuclear medicine communications 20110501
Title: Early prediction of nonprogression in advanced non-small-cell lung cancer treated with erlotinib by using [(18)F]fluorodeoxyglucose and [(18)F]fluorothymidine positron emission tomography.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501
Title: Predictive value of initial 18F-FLT uptake in patients with aggressive non-Hodgkin lymphoma receiving R-CHOP treatment.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110501
Title: Noninvasive assessment of cell proliferation in ovarian cancer using [18F] 3'deoxy-3-fluorothymidine positron emission tomography/computed tomography imaging.
Journal: Nuclear medicine and biology 20110501
Title: Postchemotherapy residual masses in nonseminomatous germ cell tumor patients: 18F-FLT PET is unlikely to identify mature teratoma, but imaging of alphav beta3 integrin expression could.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110501
Title: [Positron emission tomography - current role in the diagnosis and treatment of upper gastrointestinal carcinomas].
Journal: Deutsche medizinische Wochenschrift (1946) 20110501
Title: A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110401
Title: Increase of [(18)F]FLT tumor uptake in vivo mediated by FdUrd: toward improving cell proliferation positron emission tomography.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110401
Title: Compliance with PET acquisition protocols for therapeutic monitoring of erlotinib therapy in an international trial for patients with non-small cell lung cancer.
Journal: European journal of nuclear medicine and molecular imaging 20110401
Title: F-18 FLT PET: a noninvasive diagnostic tool for visualization of the bone marrow compartment in patients with aplastic anemia: a pilot study.
Journal: Clinical nuclear medicine 20110401
Title: PET and SPECT in brain tumors and epilepsy.
Journal: Neurosurgery clinics of North America 20110401
Title: Distribution of proliferating bone marrow in adult cancer patients determined using FLT-PET imaging.
Journal: International journal of radiation oncology, biology, physics 20110301
Title: Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110301
Title: Cumulative input function method for linear compartmental models and spectral analysis in PET.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201
Title: Can multimodality imaging using 18F-FDG/18F-FLT PET/CT benefit the diagnosis and management of patients with pulmonary lesions?
Journal: European journal of nuclear medicine and molecular imaging 20110201
Title: 18F-FLT and 18F-FDG positron emission tomography for the imaging of advanced well-differentiated gastro-entero-pancreatic endocrine tumours.
Journal: Nuclear medicine communications 20110201
Title: Auto-SCT induces a phenotypic shift from CMP to GMP progenitors, reduces clonogenic potential and enhances in vitro and in vivo cycling activity defined by (18)F-FLT PET scanning.
Journal: Bone marrow transplantation 20110101
Title: Early response assessment in prostate carcinoma by ¹⁸F-fluorothymidine following anticancer therapy with docetaxel using preclinical tumour models.
Journal: European journal of nuclear medicine and molecular imaging 20110101
Title: Simultaneous positron emission tomography (PET) assessment of metabolism with ¹⁸F-fluoro-2-deoxy-d-glucose (FDG), proliferation with ¹⁸F-fluoro-thymidine (FLT), and hypoxia with ¹⁸fluoro-misonidazole (F-miso) before and during radiotherapy in patients with non-small-cell lung cancer (NSCLC): a pilot study.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110101
Title: Effect of radiotherapy and chemotherapy on bone marrow activity: a 18F-FLT-PET study.
Journal: Nuclear medicine communications 20110101
Title: Molecular imaging metrics to evaluate response to preclinical therapeutic regimens.
Journal: Frontiers in bioscience (Landmark edition) 20110101
Title: Chondroid hamartoma presenting as solitary pulmonary nodule: results of dual time point (18)F-fluorodeoxyglucose-PET and comparison with (18)F-fluorothymidine PET and histopathology.
Journal: Hellenic journal of nuclear medicine 20110101
Title: Early detection of tumor response by FLT/microPET Imaging in a C26 murine colon carcinoma solid tumor animal model.
Journal: Journal of biomedicine & biotechnology 20110101
Title: [18F]fluorothymidine PET imaging in the diagnosis of leptomeningeal involvement with diffuse large B-cell lymphoma.
Journal: Cancer imaging : the official publication of the International Cancer Imaging Society 20110101
Title: Diagnostic usefulness of 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography in recurrent brain tumor.
Journal: Journal of computer assisted tomography 20110101
Title: Increased cellular proliferation in rat skeletal muscle and tendon in response to exercise: use of FLT and PET/CT.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20101201
Title: Biopsy targeting gliomas: do functional imaging techniques identify similar target areas?
Journal: Investigative radiology 20101201
Title: Synthesis, antiviral and contraceptive activities of nucleoside-sodium cellulose sulfate acetate and succinate conjugates.
Journal: Bioorganic & medicinal chemistry letters 20101201
Title: Repeatability of metabolically active volume measurements with 18F-FDG and 18F-FLT PET in non-small cell lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101201
Title: Induction of thymidine kinase 1 after 5-fluorouracil as a mechanism for 3'-deoxy-3'-[18F]fluorothymidine flare.
Journal: Biochemical pharmacology 20101115
Title: Selective killing of tumor neovasculature paradoxically improves chemotherapy delivery to tumors.
Journal: Cancer research 20101115
Title: Partial selective inhibition of HIV-1 reverse transcriptase and human DNA polymerases γ and β by thiated 3'-fluorothymidine analogue 5'-triphosphates.
Journal: Antiviral research 20101101
Title: 18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001
Title: Can evaluation of targeted therapy in oncology be improved by means of 18F-FLT?
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001
Title: A facile and rapid automated synthesis of 3'-deoxy-3'-[(18)F]fluorothymidine.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20100901
Title: Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901
Title: Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901
Title: Reproducibility of 18F-FDG and 3'-deoxy-3'-18F-fluorothymidine PET tumor volume measurements.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100901
Title: Extramedullary haematopoiesis imaging with 18F-FLT PET.
Journal: European journal of nuclear medicine and molecular imaging 20100801
Title: Imaging of proliferation with 18F-FLT PET/CT versus 18F-FDG PET/CT in non-small-cell lung cancer.
Journal: European journal of nuclear medicine and molecular imaging 20100701
Title: New trends in nucleoside biotechnology.
Journal: Acta naturae 20100701
Title: (18)F-fluoro-L-thymidine-PET for the evaluation of primary brain tumours in children: a report of three cases.
Journal: Nuclear medicine communications 20100601
Title: PET/CT with 18F-FLT: does it improve the therapeutic management of metastatic germ cell tumors?
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100601
Title: Monitoring tumor response to therapy with 18F-FLT PET.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100601
Title: 18F-FLT PET/CT for early response monitoring and dose escalation in oropharyngeal tumors.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100601
Title: Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity.
Journal: Nucleosides, nucleotides & nucleic acids 20100601
Title: Stability of 3'-deoxy-3'-[18F]fluorothymidine standardized uptake values in head and neck cancer over time.
Journal: Cancer biotherapy & radiopharmaceuticals 20100601
Title: 3'-bromo analogues of pyrimidine nucleosides as a new class of potent inhibitors of Mycobacterium tuberculosis.
Journal: Journal of medicinal chemistry 20100527
Title: The integration of quantitative multi-modality imaging data into mathematical models of tumors.
Journal: Physics in medicine and biology 20100507
Title: Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505
Title: A bilateral foot drop due to neuroschistosomiasis.
Journal: Journal of neurology 20100501
Title: Kinetics of 3'-deoxy-3'-18F-fluorothymidine during treatment monitoring of recurrent high-grade glioma.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100501
Title: Histopathologic validation of 3'-deoxy-3'-18F-fluorothymidine PET in squamous cell carcinoma of the oral cavity.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100501
Title: PET/CT with 18F-FLT is unlikely to cause significant hepatorenal or hematologic toxicity.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100501
Title: Investigation of the pharmacokinetics of 3'-deoxy-3'-[18F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer.
Journal: Nuclear medicine and biology 20100501
Title: Imaging pharmacodynamics in oncology: the potential significance of 'flares'.
Journal: Annals of nuclear medicine 20100401
Title: Measuring tumor cell proliferation with 18F-FLT PET during radiotherapy of esophageal squamous cell carcinoma: a pilot clinical study.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100401
Title: Comparison of (18)F-fluorothymidine and (18)F-fluorodeoxyglucose PET/CT in delineating gross tumor volume by optimal threshold in patients with squamous cell carcinoma of thoracic esophagus.
Journal: International journal of radiation oncology, biology, physics 20100315
Title: Imaging of CTLA4 blockade-induced cell replication with (18)F-FLT PET in patients with advanced melanoma treated with tremelimumab.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100301
Title: Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine.
Journal: Biochemical pharmacology 20100215
Title: Kinetic filtering of [(18)F]Fluorothymidine in positron emission tomography studies.
Journal: Physics in medicine and biology 20100207
Title: F-18-fluorothymidine-PET evaluation of bone marrow transplant in a rat model.
Journal: Nuclear medicine communications 20100201
Title: Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Journal: Bioorganic & medicinal chemistry letters 20100201
Title: Fetal dose estimates for (18)F-fluoro-L-thymidine using a pregnant monkey model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100201
Title: Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice.
Journal: PloS one 20100101
Title: Noninvasive quantification of 18F-FLT human brain PET for the assessment of tumour proliferation in patients with high-grade glioma.
Journal: European journal of nuclear medicine and molecular imaging 20091201
Title: [18F]FLT-PET and [18F]FDG-PET in the evaluation of radiotherapy for laryngeal cancer.
Journal: Oral oncology 20091201
Title: Molecular PET and PET/CT imaging of tumour cell proliferation using F-18 fluoro-L-thymidine: a comprehensive evaluation.
Journal: Nuclear medicine communications 20091201
Title: Comparative evaluation of F-18 FDOPA, F-18 FDG, and F-18 FLT-PET/CT for metabolic imaging of low grade gliomas.
Journal: Clinical nuclear medicine 20091201
Title: Imaging cellular proliferation during chemo-radiotherapy: a pilot study of serial 18F-FLT positron emission tomography/computed tomography imaging for non-small-cell lung cancer.
Journal: International journal of radiation oncology, biology, physics 20091115
Title: [PET/CT in breast cancer: an update].
Journal: Bulletin du cancer 20091101
Title: Detection of colorectal cancer using ¹⁸F-FLT PET: comparison with ¹⁸F-FDG PET.
Journal: Nuclear medicine communications 20091101
Title: Using dual-tracer PET to predict the biologic behavior of human colorectal cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091101
Title: Reproducibility of the kinetic analysis of 3'-deoxy-3'-[(18)F]fluorothymidine positron emission tomography in mouse tumor models.
Journal: Nuclear medicine and biology 20091001
Title: Imaging of proliferation in hepatocellular carcinoma with the in vivo marker 18F-fluorothymidine.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090901
Title: 18F-FLT and 18F-FDG PET to measure response to radiotherapy combined with celecoxib in two colorectal xenograft models.
Journal: International journal of radiation biology 20090901
Title: Comparison of 18F-FDG, 18F-FET and 18F-FLT for differentiation between tumor and inflammation in rats.
Journal: Nuclear medicine and biology 20090801
Title: Utilization of positron emission tomography in the management of patients with sarcoma.
Journal: Current opinion in oncology 20090701
Title: (18)F-FDG and (18)F-FLT uptake early after cyclophosphamide and mTOR inhibition in an experimental lymphoma model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701
Title: Kinetic analysis of 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in head and neck cancer patients before and early after initiation of chemoradiation therapy.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701
Title: [Use of 11F-fluorothymidine positron emission tomography in brain tumor].
Journal: No shinkei geka. Neurological surgery 20090701
Title: Molecular imaging of proliferation in vivo: positron emission tomography with [18F]fluorothymidine.
Journal: Methods (San Diego, Calif.) 20090601
Title: Molecular imaging of prostate cancer.
Journal: Methods (San Diego, Calif.) 20090601
Title: Assessment of GS-9219 in a pet dog model of non-Hodgkin's lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090515
Title: Reproducibility of quantitative 18F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography.
Journal: European journal of nuclear medicine and molecular imaging 20090301
Title: 18F-FDG and 18F-FLT do not discriminate between reactive and metastatic lymph nodes in oral cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090301
Title: Evaluation of D-18F-FMT, 18F-FDG, L-11C-MET, and 18F-FLT for monitoring the response of tumors to radiotherapy in mice.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090201
Title: Imaging regional variation of cellular proliferation in gliomas using 3'-deoxy-3'-[18F]fluorothymidine positron-emission tomography: an image-guided biopsy study.
Journal: Clinical radiology 20090101
Title: NCI-sponsored trial for the evaluation of safety and preliminary efficacy of 3'-deoxy-3'-[18F]fluorothymidine (FLT) as a marker of proliferation in patients with recurrent gliomas: preliminary efficacy studies.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101
Title: Comparison of [18F]-tracers in various experimental tumor models by PET imaging and identification of an early response biomarker for the novel microtubule stabilizer patupilone.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101
Title: [Application and future prospect of 18F-FLT PET-CT in guiding delineation of biological target volume].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090101
Title: Use of 3'-deoxy-3'-[18F]fluorothymidine PET/CT for evaluating response to cytotoxic chemotherapy in dogs with non-Hodgkin's lymphoma.
Journal: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 20090101
Title: Bone metastasis of a breast cancer detected by 3'-deoxy-3'-18F-fluorothymidine PET/CT.
Journal: Nuklearmedizin. Nuclear medicine 20090101
Title: Kinetic modeling of 3'-deoxy-3'-18F-fluorothymidine for quantitative cell proliferation imaging in subcutaneous tumor models in mice.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20081201
Title: 11C-methionine (MET) and 18F-fluorothymidine (FLT) PET in patients with newly diagnosed glioma.
Journal: European journal of nuclear medicine and molecular imaging 20081101
Title: The role of human nucleoside transporters in uptake of 3'-deoxy-3'-fluorothymidine.
Journal: Molecular pharmacology 20081101
Title: First demonstration of leukemia imaging with the proliferation marker 18F-fluorodeoxythymidine.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20081101
Title: Comparison of semiquantitative fluorescence imaging and PET tracer uptake in mesothelioma models as a monitoring system for growth and therapeutic effects.
Journal: Nuclear medicine and biology 20081101
Title: NCI-sponsored trial for the evaluation of safety and preliminary efficacy of FLT as a marker of proliferation in patients with recurrent gliomas: safety studies.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20080901
Title: Gastric cancer found on 3'-deoxy-3' F-18 fluorothymidine positron emission tomography.
Journal: Clinical nuclear medicine 20080901
Title: Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.
Journal: Molecular cancer therapeutics 20080901
Title: Autoradiographic and small-animal PET comparisons between (18)F-FMISO, (18)F-FDG, (18)F-FLT and the hypoxic selective (64)Cu-ATSM in a rodent model of cancer.
Journal: Nuclear medicine and biology 20080801
Title: Analysis and reproducibility of 3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging in patients with non-small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080715
Title: Using fluorodeoxythymidine to monitor anti-EGFR inhibitor therapy in squamous cell carcinoma xenografts.
Journal: Head & neck 20080601
Title: Imaging of cell proliferation: status and prospects.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080601
Title: Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT.
Journal: European journal of nuclear medicine and molecular imaging 20080501
Title: 3'-Sulfonylesters of 2,5'-anhydro-1-(2-deoxy-beta-d-threo-pentofuranosyl)thymine as precursors for the synthesis of [(18)F]FLT: syntheses and radiofluorination trials.
Journal: Nuclear medicine and biology 20080501
Title: Glioma proliferation as assessed by 3'-fluoro-3'-deoxy-L-thymidine positron emission tomography in patients with newly diagnosed high-grade glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080401
Title: Positron emission tomography-positive squalene-induced lipoid pneumonia confirmed by gas chromatography-mass spectrometry of bronchoalveolar lavage fluid.
Journal: The American journal of the medical sciences 20080401
Title: Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer.
Journal: European journal of nuclear medicine and molecular imaging 20080301
Title: The role of 18F-FLT in cancer imaging: does it really reflect proliferation?
Journal: European journal of nuclear medicine and molecular imaging 20080301
Title: Dynamic small-animal PET imaging of tumor proliferation with 3'-deoxy-3'-18F-fluorothymidine in a genetically engineered mouse model of high-grade gliomas.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080301
Title: Comparison of (18)F-FLT PET and (18)F-FDG PET for preoperative staging in non-small cell lung cancer.
Journal: European journal of nuclear medicine and molecular imaging 20080201
Title: A multicenter clinical trial on the diagnostic value of dual-tracer PET/CT in pulmonary lesions using 3'-deoxy-3'-18F-fluorothymidine and 18F-FDG.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080201
Title: Usefulness of 11C-methionine for differentiating tumors from granulomas in experimental rat models: a comparison with 18F-FDG and 18F-FLT.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080101
Title: Uptake of (18)F-FLT and (18)F-FDG in primary head and neck cancer correlates with survival.
Journal: Nuklearmedizin. Nuclear medicine 20080101
Title: FLT-PET imaging of radiation responses in murine tumors.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20080101
Title: Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20080101
Title: [18F]FDG and [18F]FLT PET-CT and MR imaging of human neuroblastomas in a SCID mouse xenograft model.
Journal: Anticancer research 20080101
Title: Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET).
Journal: PloS one 20080101
Title: Investigation of the role of the base in the synthesis of [18F]FLT.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20071201
Title: Imaging gastric cancer with PET and the radiotracers 18F-FLT and 18F-FDG: a comparative analysis.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20071201
Title: Early assessment of therapy response in malignant lymphoma with the thymidine analogue [18F]FLT.
Journal: European journal of nuclear medicine and molecular imaging 20071101
Title: Monitoring response to radiotherapy in human squamous cell cancer bearing nude mice: comparison of 2'-deoxy-2'-[18F]fluoro-D-glucose (FDG) and 3'-[18F]fluoro-3'-deoxythymidine (FLT).
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20071101
Title: (18)F-labeled positron emission tomographic radiopharmaceuticals in oncology: an overview of radiochemistry and mechanisms of tumor localization.
Journal: Seminars in nuclear medicine 20071101
Title: FLT: measuring tumor cell proliferation in vivo with positron emission tomography and 3'-deoxy-3'-[18F]fluorothymidine.
Journal: Seminars in nuclear medicine 20071101
Title: Correlation of 18F-FLT and 18F-FDG uptake on PET with Ki-67 immunohistochemistry in non-small cell lung cancer.
Journal: European journal of nuclear medicine and molecular imaging 20071001
Title: Effects of apricitabine and other nucleoside reverse transcriptase inhibitors on replication of mitochondrial DNA in HepG2 cells.
Journal: Antiviral research 20071001
Title: Purification of [18F]-fluoro-L-thymidine ([18F]-FLT) for positron emission tomography imaging.
Journal: Journal of pharmaceutical and biomedical analysis 20070921
Title: Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Journal: European journal of nuclear medicine and molecular imaging 20070901
Title: Simple and highly efficient synthesis of 3'-deoxy-3'-[18F]fluorothymidine using nucleophilic fluorination catalyzed by protic solvent.
Journal: European journal of nuclear medicine and molecular imaging 20070901
Title: Assessment of therapy response in malignant tumours with 18F-fluorothymidine.
Journal: European journal of nuclear medicine and molecular imaging 20070901
Title: Non-[18F]FDG PET in clinical oncology.
Journal: The Lancet. Oncology 20070901
Title: 18F-fluorothymidine kinetics of malignant brain tumors.
Journal: European journal of nuclear medicine and molecular imaging 20070701
Title: Evaluation of 5'-deoxy-5'-[F-18]fluorothymidine as a tracer of intracellular thymidine phosphorylase activity.
Journal: Nuclear medicine and biology 20070701
Title: PET imaging with [18F]3'-deoxy-3'-fluorothymidine for prediction of response to neoadjuvant treatment in patients with rectal cancer.
Journal: European journal of nuclear medicine and molecular imaging 20070601
Title: In vivo molecular imaging biomarkers: clinical pharmacology's new 'PET'?
Journal: Clinical pharmacology and therapeutics 20070601
Title: 18F-FLT PET does not discriminate between reactive and metastatic lymph nodes in primary head and neck cancer patients.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070501
Title: Synthesis and biodistribution of 3'-fluoro-5-[(131)I]iodo-2'-deoxyuridine: a comparative study of [(131)I]FLIdU and [(18)F]FLT.
Journal: Nuclear medicine and biology 20070401
Title: In vitro characterization of the thyroidal uptake of O-(2-[(18)F]fluoroethyl)-L-tyrosine.
Journal: Nuclear medicine and biology 20070401
Title: 3'-deoxy-3'-(18)F-fluorothymidine (FLT) positron emission tomography for early prediction of response to chemoradiotherapy--a clinical application model of esophageal cancer.
Journal: Seminars in oncology 20070401
Title: The SUV and FLT PET: a tasty alphabet soup or a dog's breakfast?
Journal: Leukemia & lymphoma 20070401
Title: Functional diagnosis of residual lymphomas after radiochemotherapy with positron emission tomography comparing FDG- and FLT-PET.
Journal: Leukemia & lymphoma 20070401
Title: Antiviral activity of low-dose alovudine in antiretroviral-experienced patients: results from a 4-week randomized, double-blind, placebo-controlled dose-ranging trial.
Journal: HIV medicine 20070401
Title: 18F-fluorodeoxythymidine PET for evaluating the response to hyperthermic isolated limb perfusion for locally advanced soft-tissue sarcomas.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070301
Title: Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070301
Title: Imaging-guided gene therapy of experimental gliomas.
Journal: Cancer research 20070215
Title: Impact of integrated PET/CT on variability of target volume delineation in rectal cancer.
Journal: Technology in cancer research & treatment 20070201
Title: Application of solid-phase chemistry for the synthesis of 3'-fluoro-3'-deoxythymidine.
Journal: Nucleosides, nucleotides & nucleic acids 20070101
Title: Serial integrated (18)F-fluorodeoxythymidine PET/CT monitoring neoadjuvant chemotherapeutic response in invasive ductal carcinoma.
Journal: The breast journal 20070101
Title: Evaluation of primary brain tumors with FLT-PET: usefulness and limitations.
Journal: Clinical nuclear medicine 20061201
Title: Fluorine-18 fluorothymidine: a new positron emission radioisotope for renal tumors.
Journal: Clinical nuclear medicine 20061201
Title: [Correlation of 3'-deoxy-3'-18F-fluorothymidine uptake to cell proliferation in lung carcinoma xenografts].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20061201
Title: Functional imaging for early prediction of response to chemoradiotherapy: 3'-deoxy-3'-18F-fluorothymidine positron emission tomography--a clinical application model of esophageal cancer.
Journal: Seminars in oncology 20061201
Title: Molecular imaging of proliferation in malignant lymphoma.
Journal: Cancer research 20061115
Title: 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061001
Title: Kinetic analysis of 3'-deoxy-3'-18F-fluorothymidine in patients with gliomas.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061001
Title: Quantifying the activity of adenoviral E1A CR2 deletion mutants using renilla luciferase bioluminescence and 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography imaging.
Journal: Cancer research 20060915
Title: [PET and malignant cerebral tumors].
Journal: Presse medicale (Paris, France : 1983) 20060901
Title: Clinical molecular imaging with positron emission tomography.
Journal: European journal of cancer (Oxford, England : 1990) 20060801
Title: In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Journal: Cancer research 20060801
Title: Early detection of chemoradioresponse in esophageal carcinoma by 3'-deoxy-3'-3H-fluorothymidine using preclinical tumor models.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Is 3'-deoxy-3'-(18)F-fluorothymidine a better marker for tumour response than (18)F-fluorodeoxyglucose?
Journal: European journal of nuclear medicine and molecular imaging 20060701
Title: Use of 3'-deoxy-3'-[18F]fluorothymidine PET to monitor early responses to radiation therapy in murine SCCVII tumors.
Journal: European journal of nuclear medicine and molecular imaging 20060401
Title: Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033.
Journal: European journal of nuclear medicine and molecular imaging 20060401
Title: 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Journal: Bioorganic & medicinal chemistry letters 20060215
Title: Semiautomatic synthesis of 3'-deoxy-3'-[18F]fluorothymidine using three precursors.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20060201
Title: Positron emission tomography in patients with breast cancer using (18)F-3'-deoxy-3'-fluoro-l-thymidine ((18)F-FLT)-a pilot study.
Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 20060201
Title: Evaluation of thoracic tumors with 18F-fluorothymidine and 18F-fluorodeoxyglucose-positron emission tomography.
Journal: Chest 20060201
Title: Acquisition of resistance to antitumor alkylating agent ACNU: a possible target of positron emission tomography monitoring.
Journal: Nuclear medicine and biology 20060101
Title: The effect of a methyl or 2-fluoroethyl substituent at the N-3 position of thymidine, 3'-fluoro-3'-deoxythymidine and 1-beta-D-arabinosylthymine on their antiviral and cytostatic activity in cell culture.
Journal: Antiviral chemistry & chemotherapy 20060101
Title: Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.
Journal: Bioorganic & medicinal chemistry 20051215
Title: 18F-fluoro-L-thymidine and 11C-methylmethionine as markers of increased transport and proliferation in brain tumors.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051201
Title: Advances in positron emission tomographic imaging of lung cancer.
Journal: Proceedings of the American Thoracic Society 20051201
Title: A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention.
Journal: European journal of nuclear medicine and molecular imaging 20051101
Title: Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine-positron emission tomography imaging: evaluation of analytical methods.
Journal: Cancer research 20051101
Title: Reproducibility of 3'-deoxy-3'-(18)F-fluorothymidine microPET studies in tumor xenografts in mice.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20051101
Title: True tracers: comparing FDG with glucose and FLT with thymidine.
Journal: Nuclear medicine and biology 20051001
Title: [Is 3'-deoxy-3'- [18F] fluorothymidine ([18F]-FLT) the next tracer for routine clinical PET after R [18F]-FDG?].
Journal: Bulletin du cancer 20050901
Title: Molecular imaging in animal models of disease--every little detail counts!
Journal: European journal of nuclear medicine and molecular imaging 20050801
Title: [18F]3'-deoxy-3'-fluorothymidine PET for the diagnosis and grading of brain tumors.
Journal: European journal of nuclear medicine and molecular imaging 20050601
Title: Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050601
Title: Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo.
Journal: Cancer research 20050515
Title: Clinical relevance of imaging proliferative activity in lung nodules.
Journal: European journal of nuclear medicine and molecular imaging 20050501
Title: Emerging anti-HIV drugs.
Journal: Expert opinion on emerging drugs 20050501
Title: Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: Comparison of 18F-FLT PET and 18F-FDG PET in esophageal cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050301
Title: The uptake of 3'-deoxy-3'-[18F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels.
Journal: European journal of nuclear medicine and molecular imaging 20050301
Title: Kinetic analysis of 3'-deoxy-3'-fluorothymidine PET studies: validation studies in patients with lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201
Title: Kinetic modeling of 3'-deoxy-3'-fluorothymidine in somatic tumors: mathematical studies.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201
Title: Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3'-deoxy-3'-18F-fluorothymidine PET.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050101
Title: Molecular imaging: what can be used today.
Journal: Cancer imaging : the official publication of the International Cancer Imaging Society 20050101
Title: [18F]FLT-PET in oncology: current status and opportunities.
Journal: European journal of nuclear medicine and molecular imaging 20041201
Title: New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections.
Journal: Current opinion in pharmacology 20041001
Title: Metabolism of 3'-deoxy-3'-[F-18]fluorothymidine in proliferating A549 cells: validations for positron emission tomography.
Journal: Nuclear medicine and biology 20041001
Title: Is 18F-3'-fluoro-3'-deoxy-L-thymidine useful for the staging and restaging of non-small cell lung cancer?
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20041001
Title: Evaluation of 3'-deoxy-3'-18F-fluorothymidine for monitoring tumor response to radiotherapy and photodynamic therapy in mice.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20041001
Title: [Fluorinated analogs of nucleosides and fluorinated tracers of gene expression for positron emission tomography].
Journal: Bulletin du cancer 20040901
Title: Fully automated synthesis system of 3'-deoxy-3'-[18F]fluorothymidine.
Journal: Nuclear medicine and biology 20040801
Title: [18F]3'-deoxy-3'-fluorothymidine-PET in NHL patients: whole-body biodistribution and imaging of lymphoma manifestations--a pilot study.
Journal: Cancer biotherapy & radiopharmaceuticals 20040801
Title: MIV-310 reduces HIV viral load in patients failing multiple antiretroviral therapy: results from a 4-week phase II study.
Journal: AIDS (London, England) 20040618
Title: Assessment of recurrent colorectal cancer following 5-fluorouracil chemotherapy using both 18FDG and 18FLT PET.
Journal: European journal of nuclear medicine and molecular imaging 20040601
Title: PET with [18F]fluorothymidine for imaging of primary breast cancer: a pilot study.
Journal: European journal of nuclear medicine and molecular imaging 20040501
Title: Effect of p53 activation on cell growth, thymidine kinase-1 activity, and 3'-deoxy-3'fluorothymidine uptake.
Journal: Nuclear medicine and biology 20040501
Title: Designing a pronucleotide stratagem: lessons from amino acid phosphoramidates of anticancer and antiviral pyrimidines.
Journal: Mini reviews in medicinal chemistry 20040501
Title: Positron emission tomography imaging of cell proliferation in oncology.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20040501
Title: Selectivity of 18F-FLT and 18F-FDG for differentiating tumor from inflammation in a rodent model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040401
Title: Monitoring of therapy in androgen-dependent prostate tumor model by measuring tumor proliferation.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040301
Title: Detection and grading of soft tissue sarcomas of the extremities with (18)F-3'-fluoro-3'-deoxy-L-thymidine.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040301
Title: 18F-FLT PET for visualization of laryngeal cancer: comparison with 18F-FDG PET.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040201
Title: Comparison of methodologies for the in vivo assessment of 18FLT utilisation in colorectal cancer.
Journal: European journal of nuclear medicine and molecular imaging 20040201
Title: 3'-18F-fluoro-3'-deoxy-L-thymidine: a new tracer for staging metastatic melanoma?
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20031201
Title: Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20031201
Title: Correspondence re: H. Barthel et al., 3'-deoxy-3'-[(18)F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. Cancer Res., 63: 3791-3798, 2003.
Journal: Cancer research 20031201
Title: Effect of probenecid and quinidine on the transport of alovudine (3'-fluorothymidine) to the rat brain studied by microdialysis.
Journal: Pharmacology & toxicology 20031101
Title: [18F]FLT PET for diagnosis and staging of thoracic tumours.
Journal: European journal of nuclear medicine and molecular imaging 20031001
Title: Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Journal: Bioorganic & medicinal chemistry letters 20030915
Title: Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901
Title: PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901
Title: 18F-Fluorothymidine radiation dosimetry in human PET imaging studies.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901
Title: Potential impact of [18F]3'-deoxy-3'-fluorothymidine versus [18F]fluoro-2-deoxy-D-glucose in positron emission tomography for colorectal cancer.
Journal: European journal of nuclear medicine and molecular imaging 20030701
Title: 3'-deoxy-3'-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography.
Journal: Cancer research 20030701
Title: 3'-[18F]fluoro-3'-deoxythymidine ([18F]-FLT) as positron emission tomography tracer for imaging proliferation in a murine B-Cell lymphoma model and in the human disease.
Journal: Cancer research 20030515
Title: Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.
Journal: Antiviral chemistry & chemotherapy 20030501
Title: High radiochemical yield synthesis of 3'-deoxy-3'-[18F]fluorothymidine using (5'-O-dimethoxytrityl-2'-deoxy-3'-O-nosyl-beta-D-threo pentofuranosyl)thymine and its 3-N-BOC-protected analogue as a labeling precursor.
Journal: Nuclear medicine and biology 20030201
Title: Alovudine Medivir.
Journal: Current opinion in investigational drugs (London, England : 2000) 20030201
Title: Thiated analogues of 2',3'-dideoxy-3'-fluorothymidine and their phosphorylated and phosphonylated derivatives: synthesis, interaction with HIV reverse transcriptase, and in vitro anti-HIV activity.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: Rat studies comparing 11C-FMAU, 18F-FLT, and 76Br-BFU as proliferation markers.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021201
Title: Early changes in [18F]FLT uptake after chemotherapy: an experimental study.
Journal: European journal of nuclear medicine and molecular imaging 20021101
Title: In vivo validation of 3'deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) as a proliferation imaging tracer in humans: correlation of [(18)F]FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021101
Title: Evaluation of pyrimidine metabolising enzymes and in vitro uptake of 3'-[(18)F]fluoro-3'-deoxythymidine ([(18)F]FLT) in pancreatic cancer cell lines.
Journal: European journal of nuclear medicine and molecular imaging 20020901
Title: Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020901
Title: 3-deoxy-3-[(18)F]fluorothymidine-positron emission tomography for noninvasive assessment of proliferation in pulmonary nodules.
Journal: Cancer research 20020615
Title: A new precursor for the radiosynthesis of [18F]FLT.
Journal: Nuclear medicine and biology 20020201
Title: [18F]FLT; portrait of a proliferation marker.
Journal: European journal of nuclear medicine and molecular imaging 20020201
Title: Anti-HIV type 1 activity of 3'-fluoro-3'-deoxythymidine for several different multidrug-resistant mutants.
Journal: AIDS research and human retroviruses 20010320
Title: Synthesis, in vitro anti-HIV activity, and biological stability of 5'-O-myristoyl analogue derivatives of 3'-fluoro-2',3'-dideoxythymidine (FLT) as potential bifunctional prodrugs of FLT.
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Title: In vitro anti-hepatitis B virus activities of 5'-O-myristoyl analogue derivatives of 3'-fluoro-2',3'-dideoxythymidine (FLT) and 3'-azido-2',3'-dideoxythymidine (AZT).
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Title: Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs.
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Title: Synthesis of 4-methylthio analogues of FLT and AZT and their evaluation against HIV.
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Title: Comparison of the sensitivities of primary isolates of HIV type 2 and HIV type 1 to antiviral drugs and drug combinations.
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Title: Synthesis and antiviral (HIV-1, HBV) activities of 5-halo-6-methoxy(or azido)-5,6-dihydro-3'-fluoro-3'-deoxythymidine diastereomers. Potential prodrugs to 3'-fluoro-3'-deoxythymidine.
Journal: Journal of medicinal chemistry 19941014
Title: 5-Chloro-2',3'-dideoxy-3'-fluorouridine (935U83), a selective anti-human immunodeficiency virus agent with an improved metabolic and toxicological profile.
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Title: Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
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Title: Syntheses and biological evaluations of 3'-deoxy-3'-C-branched-chain-substituted nucleosides.
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Title: 3',3'-Difluoro-3'-deoxythymidine: comparison of anti-HIV activity to 3'-fluoro-3'-deoxythymidine.
Journal: Journal of medicinal chemistry 19920904
Title: Long-term tolerance and efficacy of 3'-azidothymidine and 3'-fluorothymidine treatment of asymptomatic monkeys infected with simian immunodeficiency virus.
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Title: Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication.
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Title: Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.
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Title: Fluorinated sugar analogues of potential anti-HIV-1 nucleosides.
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Title: Synergistic combinations and peptides in the inhibition of human immunodeficiency virus.
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Title: Antiviral effects of 3'-fluorothymidine and 3'-azidothymidine in cynomolgus monkeys infected with simian immunodeficiency virus.
Journal: Journal of acquired immune deficiency syndromes 19910101
Title: Synergistic inhibition of human immunodeficiency virus replication in vitro by combinations of 3'-azido-3'-deoxythymidine and 3'-fluoro-3'-deoxythymidine.
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Title: 5'-O-phosphonomethyl-2',3'-dideoxynucleosides: synthesis and anti-HIV activity.
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Title: In vitro screening for antiretroviral agents against simian immunodeficiency virus (SIV).
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Title: Susceptibility to nucleoside analogues of zidovudine-resistant isolates of human immunodeficiency virus.
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Title: Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virus.
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Title: Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1.
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Title: Inhibition of HIV-replication by 3'-fluoro-modified nucleosides with low cytotoxicity.
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Title: An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs.
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