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28860-95-9,MFCD00889211
Catalog No.:AA00I5B4

28860-95-9 | 3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid

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1mg
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$13.00   $9.00
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10mg
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$42.00   $29.00
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1g
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$54.00   $38.00
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5g
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$120.00   $84.00
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10g
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$178.00   $125.00
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25g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I5B4
Chemical Name:
3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid
CAS Number:
28860-95-9
Molecular Formula:
C10H14N2O4
Molecular Weight:
226.2292
MDL Number:
MFCD00889211
SMILES:
NN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C
NSC Number:
751137
Properties
Computed Properties
 
Complexity:
261  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
4  
XLogP3:
-2.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:SERVIERMONDE-WO2007/42848,2007,A2Locationinpatent:Page/Pagecolumn21

[1]CurrentPatentAssignee:KANDULA,mahesh-WO2013/17974,2013,A1Locationinpatent:Paragraph00205-00206

[2]CurrentPatentAssignee:CELLIXBIOPRIVATELTD-WO2013/168021,2013,A1Locationinpatent:Paragraph00132;00133

[3]CurrentPatentAssignee:CELLIXBIOPRIVATELTD-US2016/122293,2016,A1Locationinpatent:Paragraph0144;0145

24424-99-5    28860-95-9   
CASUnavailable 

[1]CurrentPatentAssignee:KANDULA,mahesh-WO2013/17974,2013,A1Locationinpatent:Paragraph00213-00214

[2]CurrentPatentAssignee:CELLIXBIOPRIVATELTD-WO2013/168021,2013,A1Locationinpatent:Paragraph00123;00124

[3]CurrentPatentAssignee:CELLIXBIOPRIVATELTD-US2016/122293,2016,A1Locationinpatent:Paragraph0135;0136

13139-17-8    28860-95-9   
CASUnavailable 

[1]CurrentPatentAssignee:ABBVIEINC-WO2016/65019,2016,A1Locationinpatent:Paragraph0317;0319

[2]CurrentPatentAssignee:ABBVIEINC-US2019/224220,2019,A1Locationinpatent:Paragraph0398;0401

28860-95-9    501-53-1   
CASUnavailable 

[1]CurrentPatentAssignee:ABBVIEINC-WO2016/65019,2016,A1Locationinpatent:Paragraph0323;0325

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Title: Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.

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Title: Electrocatalytic oxidation and voltammetric determination of levodopa in the presence of carbidopa at the surface of a nanostructure based electrochemical sensor.

Journal: Biosensors & bioelectronics 20120515

Title: Functional and physiological effects of treadmill training induced by buspirone, carbidopa, and L-DOPA in clenbuterol-treated paraplegic mice.

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Journal: The Analyst 20120421

Title: Trichophagia affects response to duodenal levodopa/carbidopa gel administration.

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Journal: Journal of plant physiology 20120315

Title: Long-term exposure to duodenal levodopa/carbidopa infusion therapy improves quality of life in relation especially to mobility, activities of daily living, and emotional well-being.

Journal: Acta neurologica Scandinavica 20120301

Title: Malnutritional neuropathy under intestinal levodopa infusion.

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Title: The effect of different dosing regimens of levodopa/carbidopa/entacapone on plasma levodopa concentrations.

Journal: European journal of clinical pharmacology 20120301

Title: Parkinson's disease patients cannot get their dopamine replacement: the 8-Sinemet limit.

Journal: Movement disorders : official journal of the Movement Disorder Society 20120301

Title: Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120301

Title: Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?

Journal: Endocrine pathology 20120301

Title: Optimizing levodopa therapy to treat wearing-off symptoms in Parkinson's disease: focus on levodopa/carbidopa/entacapone.

Journal: Expert review of neurotherapeutics 20120201

Title: IPX066: a novel carbidopa-levodopa extended-release formulation.

Journal: Expert review of neurotherapeutics 20120201

Title: Clinical inquiry. Which drugs work best for early Parkinson's disease?

Journal: The Journal of family practice 20120201

Title: Parkinsonism and dropped head: dystonia, myopathy or both?

Journal: Parkinsonism & related disorders 20120101

Title: Ocular motor and sensory function in Parkinson's disease.

Journal: Ophthalmology 20120101

Title: Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs).

Journal: Gut 20120101

Title: Complexity of motor response to different doses of duodenal levodopa infusion in Parkinson disease.

Journal: Clinical neuropharmacology 20120101

Title: The dopamine augmenter L-DOPA does not affect positive mood in healthy human volunteers.

Journal: PloS one 20120101

Title: No differential regulation of dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) binding in a primate model of Parkinson disease.

Journal: PloS one 20120101

Title: Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors.

Journal: PloS one 20120101

Title: The role of GRK6 in animal models of Parkinson's disease and L-DOPA treatment.

Journal: Scientific reports 20120101

Title: CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis.

Journal: PloS one 20120101

Title: Actively transported levodopa prodrug XP21279: a study in patients with Parkinson disease who experience motor fluctuations.

Journal: Clinical neuropharmacology 20120101

Title: Levodopa in combination with carbidopa does not affect plasma arginine vasopressin levels in treatment-naïve older patients with Parkinson's disease: A before-after study.

Journal: Neuro endocrinology letters 20120101

Title: Vancomycin-induced Henoch-Schönlein purpura: a case report.

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Title: Dyskinesias and treatment with pramipexole in patients with Parkinson's disease.

Journal: Parkinson's disease 20120101

Title: Pharmacological enhancement of treatment for amblyopia.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20120101

Title: Pharmacokinetics of levodopa/carbidopa microtablets versus levodopa/benserazide and levodopa/carbidopa in healthy volunteers.

Journal: Clinical neuropharmacology 20120101

Title: Accounting for movement increases sensitivity in detecting brain activity in Parkinson's disease.

Journal: PloS one 20120101

Title: Dopamine agonists and pathologic behaviors.

Journal: Parkinson's disease 20120101

Title: Role of gabapentin enacarbil XR in restless legs syndrome.

Journal: Therapeutics and clinical risk management 20120101

Title: Flow-based systems for rapid and high-precision enzyme kinetics studies.

Journal: Journal of analytical methods in chemistry 20120101

Title: Toward the understanding of the metabolism of levodopa I. DFT investigation of the equilibrium geometries, acid-base properties and levodopa-water complexes.

Journal: International journal of molecular sciences 20120101

Title: Relative nutritional deficiencies associated with centrally acting monoamines.

Journal: International journal of general medicine 20120101

Title: Stem cells as in vitro model of Parkinson's disease.

Journal: Stem cells international 20120101

Title: Electrochemically pretreated carbon microfiber electrodes as sensitive HPLC-EC detectors.

Journal: TheScientificWorldJournal 20120101

Title: Modified carbon nanotube paste electrode for voltammetric determination of carbidopa, folic Acid, and tryptophan.

Journal: Journal of analytical methods in chemistry 20120101

Title: Parallel appearance of compulsive behaviors and artistic creativity in Parkinson's disease.

Journal: Case reports in neurology 20120101

Title: [A combined preparation stalevo in Parkinson's disease: a 5-year experience of continuous dopaminergic stimulation].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

Title: The Antiparkinsonian and Antidyskinetic Mechanisms of Mucuna pruriens in the MPTP-Treated Nonhuman Primate.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Isolated extra pontine myelinolysis presenting as acute onset parkinsonism.

Journal: BMJ case reports 20120101

Title: Simultaneous quantitation of levodopa and 3-O-methyldopa in human plasma by HPLC-ESI-MS/MS: application for a pharmacokinetic study with a levodopa/benserazide formulation.

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Title: Levodopa-induced breathing, cognitive and behavioral changes in Parkinson's disease.

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Journal: Brain imaging and behavior 20110901

Title: The use of mouse models to understand and improve cognitive deficits in Down syndrome.

Journal: Disease models & mechanisms 20110901

Title: Development and validation of a high-performance liquid chromatography-electrospray ionization-MS/MS method for the simultaneous quantitation of levodopa and carbidopa in human plasma.

Journal: Journal of mass spectrometry : JMS 20110901

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Title: Relationship between 3-O-methyldopa and the clinical effects of entacapone in advanced Parkinson's disease.

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Title: Inhibition of catechol-O-methyltransferase modifies acute homocysteine rise during repeated levodopa application in patients with Parkinson's disease.

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Journal: European journal of neurology 20110401

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Title: Influence of ageing on the pharmacokinetics of levodopa in elderly patients with Parkinson's disease.

Journal: Parkinsonism & related disorders 20110301

Title: Autism associated with low 5-hydroxyindolacetic acid in CSF and the heterozygous SLC6A4 gene Gly56Ala plus 5-HTTLPR L/L promoter variants.

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Journal: Archives of Iranian medicine 20110301

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Journal: The Israel Medical Association journal : IMAJ 20110301

Title: Determination of L-dopa, carbidopa, 3-O-methyldopa and entacapone in human plasma by HPLC-ED.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: A tale of two tauopathies.

Journal: Neurology 20110215

Title: Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients.

Journal: Movement disorders : official journal of the Movement Disorder Society 20110215

Title: Transcutaneous port for continuous duodenal levodopa/carbidopa administration in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20110201

Title: Behavioural and pharmacological examinations in a transgenic mouse model of early-onset torsion dystonia.

Journal: Pharmacology, biochemistry, and behavior 20110201

Title: Clinical problems in the hospitalized Parkinson's disease patient: systematic review.

Journal: Movement disorders : official journal of the Movement Disorder Society 20110201

Title: Effects of carbidopa and entacapone on the metabolic fate of the norepinephrine prodrug L-DOPS.

Journal: Journal of clinical pharmacology 20110101

Title: Oxidative stress and aminopeptidases in Parkinson's disease patients with and without treatment.

Journal: Neuro-degenerative diseases 20110101

Title: Clinical and biochemical characterization of patients with early infantile onset of autosomal recessive GTP cyclohydrolase I deficiency without hyperphenylalaninemia.

Journal: Movement disorders : official journal of the Movement Disorder Society 20110101

Title: Delayed-onset parkinsonian tremor following a mesencephalic lesion.

Journal: Parkinsonism & related disorders 20110101

Title: The association between adherence to levodopa/carbidopa/entacapone therapy and healthcare utilization and costs among patients with Parkinson's disease: a retrospective claims-based analysis.

Journal: CNS drugs 20110101

Title: Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions.

Journal: BMC musculoskeletal disorders 20110101

Title: [Treatment of non-motor fluctuations with combined drug stalevo in patients with Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

Title: Adenosine A(2A) receptors measured with [C]TMSX PET in the striata of Parkinson's disease patients.

Journal: PloS one 20110101

Title: Increased plasma arginine vasopressin levels in dopamine agonist-treated Parkinson's disease patients.

Journal: Neuro endocrinology letters 20110101

Title: Subregional 6-[18F]fluoro-ʟ-m-tyrosine uptake in the striatum in Parkinson's disease.

Journal: BMC neurology 20110101

Title: Amino acid management of Parkinson's disease: a case study.

Journal: International journal of general medicine 20110101

Title: Dopamine-induced nonmotor symptoms of Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Available and emerging treatments for Parkinson's disease: a review.

Journal: Drug design, development and therapy 20110101

Title: [Levodopa medications in the treatment of Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

Title: Visual symptoms in Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease.

Journal: Alzheimer's research & therapy 20110101

Title: A cost-effectiveness analysis of levodopa/carbidopa intestinal gel compared to standard care in late stage Parkinson's disease in the UK.

Journal: Journal of medical economics 20110101

Title: Bifrontal ECT for drug-induced psychosis in Parkinson's disease.

Journal: Indian journal of psychiatry 20110101

Title: Electrophysiological effects of trace amines on mesencephalic dopaminergic neurons.

Journal: Frontiers in systems neuroscience 20110101

Title: Parkinson's disease and anaesthesia.

Journal: Indian journal of anaesthesia 20110101

Title: APRESS: apical regulatory super system, serotonin, and dopamine interaction.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Validity of urinary monoamine assay sales under the 'spot baseline urinary neurotransmitter testing marketing model'.

Journal: International journal of nephrology and renovascular disease 20110101

Title: Bladder, bowel, and sexual dysfunction in Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: A perfusion MRI study of emotional valence and arousal in Parkinson's disease.

Journal: Parkinson's disease 20110101

Title: Acoustic Analysis of PD Speech.

Journal: Parkinson's disease 20110101

Title: Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson's disease.

Journal: Pharmacological reports : PR 20110101

Title: Effect of a single dose of standard levodopa on cardiac autonomic function in Parkinson's disease.

Journal: Neurology India 20110101

Title: [Nocturnal motor symptoms of Parkinson's disease and their treatment with the three-component drug levodopa/carbidopa/entacapone].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

Title: Clinicoradiological changes of brain NK/T cell lymphoma manifesting pure akinesia: a case report.

Journal: BMC neurology 20110101

Title: Liposomes for Targeted Delivery of Active Agents against Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).

Journal: Journal of drug delivery 20110101

Title: Pregnancy in multiple system atrophy: a case report.

Journal: Journal of medical case reports 20110101

Title: Inter-hemispheric asymmetry of nigrostriatal dopaminergic lesion: a possible compensatory mechanism in Parkinson's disease.

Journal: Frontiers in systems neuroscience 20110101

Title: Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons.

Journal: ISRN neurology 20110101

Title: 5-HT(1A) receptor activation improves anti-cataleptic effects of levodopa in 6-hydroxydopamine-lesioned rats.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: Pheochromocytoma and paraganglioma: current functional and future molecular imaging.

Journal: Frontiers in oncology 20110101

Title: 'You never told me I would turn into a gambler': a first person account of dopamine agonist--induced gambling addiction in a patient with restless legs syndrome.

Journal: BMJ case reports 20110101

Title: Carbidopa/levodopa pharmacy errors in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20101215

Title: Comparison of orally dissolving carbidopa/levodopa (Parcopa) to conventional oral carbidopa/levodopa: A single-dose, double-blind, double-dummy, placebo-controlled, crossover trial.

Journal: Movement disorders : official journal of the Movement Disorder Society 20101215

Title: A double-blind, randomized, placebo and active-controlled study of nebicapone for the treatment of motor fluctuations in Parkinson's disease.

Journal: CNS neuroscience & therapeutics 20101201

Title: Seniors with Parkinson's disease: initial medical treatment.

Journal: Journal of clinical neurology (Seoul, Korea) 20101201

Title: Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study.

Journal: The Lancet. Neurology 20101126

Title: Tremor following ischemic stroke of the posterior thalamus.

Journal: Journal of neurology 20101101

Title: Night-time bioavailability of levodopa/carbidopa/entacapone is higher compared to controlled-release levodopa/carbidopa.

Journal: International journal of clinical pharmacology and therapeutics 20101101

Title: Parkinson disease: adjunctive entacapone therapy increases risk of dyskinesia.

Journal: Nature reviews. Neurology 20101101

Title: Levodopa-responsive parkinsonism after aneurysmal subarachnoid hemorrhage.

Journal: Neurocritical care 20101001

Title: Levodopa-carbidopa may improve vision loss in indirect traumatic optic neuropathy.

Journal: Journal of neurotrauma 20101001

Title: Melevodopa/carbidopa effervescent formulation in the treatment of motor fluctuations in advanced Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100915

Title: Increasing dopamine levels in the brain improves feedback-based procedural learning in healthy participants: an artificial-grammar-learning experiment.

Journal: Neuropsychologia 20100901

Title: Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice.

Journal: Psychopharmacology 20100901

Title: An interaction between levodopa and enteral nutrition resulting in neuroleptic malignant-like syndrome and prolonged ICU stay.

Journal: The Annals of pharmacotherapy 20100901

Title: Effects of slowed gastrointestinal motility on levodopa pharmacokinetics.

Journal: Autonomic neuroscience : basic & clinical 20100825

Title: Development of a dopaminergic system in sea urchin embryos and larvae.

Journal: The Journal of experimental biology 20100815

Title: Simultaneous voltammetric determination of levodopa, carbidopa and benserazide in pharmaceuticals using multivariate calibration.

Journal: Talanta 20100815

Title: Entacapone.

Journal: Expert opinion on drug metabolism & toxicology 20100801

Title: [The effect of Stalevo-dosing on quality of life of Parkinsonian patients with wearing-off].

Journal: Ideggyogyaszati szemle 20100730

Title: Kinetic approach for the enzymatic determination of levodopa and carbidopa assisted by multivariate curve resolution-alternating least squares.

Journal: Analytica chimica acta 20100712

Title: Factors associated with motor fluctuations and dyskinesia in Parkinson Disease: potential role of a new melevodopa plus carbidopa formulation (Sirio).

Journal: Clinical neuropharmacology 20100701

Title: Adherence with levodopa/carbidopa/entacapone versus levodopa/carbidopa and entacapone as separate tablets in patients with Parkinson's disease.

Journal: Current medical research and opinion 20100701

Title: [Intraduodenal infusion of levodopa].

Journal: Revista de neurologia 20100701

Title: Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study.

Journal: Annals of neurology 20100701

Title: Development and validation of a quantitative, high-throughput, fluorescent-based bioassay to detect schistosoma viability.

Journal: PLoS neglected tropical diseases 20100701

Title: The timing of administration, dose dependence and efficacy of dopa decarboxylase inhibitors on the reversal of motor disability produced by L-DOPA in the MPTP-treated common marmoset.

Journal: European journal of pharmacology 20100610

Title: Caffeic acid improves the bioavailability of L-dopa in rabbit plasma.

Journal: Phytotherapy research : PTR 20100601

Title: Contingency management and levodopa-carbidopa for cocaine treatment: a comparison of three behavioral targets.

Journal: Experimental and clinical psychopharmacology 20100601

Title: Quantitative analysis of levodopa, carbidopa and methyldopa in human plasma samples using HPLC-DAD combined with second-order calibration based on alternating trilinear decomposition algorithm.

Journal: Talanta 20100515

Title: Cutting the Gordian knot: the blockage of the jejunal tube, a rare complication of Duodopa infusion treatment.

Journal: Journal of medicine and life 20100515

Title: Pharmacokinetic-pharmacodynamic modeling of levodopa in patients with advanced Parkinson disease.

Journal: Clinical neuropharmacology 20100501

Title: Computational identification of uncharacterized cruzain binding sites.

Journal: PLoS neglected tropical diseases 20100501

Title: Replacing a dopamine agonist by the COMT-inhibitor tolcapone as an adjunct to L-dopa in the treatment of Parkinson's disease: a randomized, multicenter, open-label, parallel-group study.

Journal: Clinical neuropharmacology 20100501

Title: Quantitative expression analysis and prognostic significance of L-DOPA decarboxylase in colorectal adenocarcinoma.

Journal: British journal of cancer 20100427

Title: Hypothalamic glutamate levels following serotonergic stimulation: a pilot study using 7-Tesla magnetic resonance spectroscopy in healthy volunteers.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100416

Title: Oral administration of a tri-therapy for central pattern generator activation in paraplegic mice: proof-of-concept of efficacy.

Journal: Biotechnology journal 20100401

Title: Working memory fMRI activation in cocaine-dependent subjects: association with treatment response.

Journal: Psychiatry research 20100330

Title: Direct switch from levodopa/benserazide or levodopa/carbidopa to levodopa/carbidopa/entacapone in Parkinson's disease patients with wearing-off: efficacy, safety and feasibility--an open-label, 6-week study.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100301

Title: The impact of levodopa on quality of life in patients with Parkinson disease.

Journal: The neurologist 20100301

Title: Evaluation and optimization of preparative variables for controlled-release floating microspheres of levodopa/carbidopa.

Journal: Die Pharmazie 20100301

Title: The effect of peripheral enzyme inhibitors on levodopa concentrations in blood and CSF.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100215

Title: Pramipexole combined with levodopa improves motor function but reduces dyskinesia in MPTP-treated common marmosets.

Journal: Movement disorders : official journal of the Movement Disorder Society 20100215

Title: Responsiveness of motor and nonmotor symptoms of Parkinson disease to dopaminergic therapy.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100201

Title: Neuroprotective effects of zonisamide target astrocyte.

Journal: Annals of neurology 20100201

Title: Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.

Journal: Journal of psychopharmacology (Oxford, England) 20100101

Title: Treatment of obesity with 'combination' pharmacotherapy.

Journal: American journal of therapeutics 20100101

Title: The dopamine D(2) receptor partial agonist aplindore improves motor deficits in MPTP-treated common marmosets alone and combined with L-dopa.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100101

Title: 5-HT precursor loading, but not 5-HT receptor agonists, increases motor function after spinal cord contusion in adult rats.

Journal: Experimental neurology 20100101

Title: Clinical experiences with levodopa methylester (melevodopa) in patients with Parkinson disease experiencing motor fluctuations: an open-label observational study.

Journal: Clinical neuropharmacology 20100101

Title: Sildenafil induced choreoathetosis in men with Parkinson's disease.

Journal: International journal of clinical pharmacology and therapeutics 20100101

Title: Cardiovascular magnetic resonance and PET-CT of left atrial paraganglioma.

Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20100101

Title: Clinical profile of parkinsonism and Parkinson's disease in Lagos, Southwestern Nigeria.

Journal: BMC neurology 20100101

Title: Crystal structure and substrate specificity of Drosophila 3,4-dihydroxyphenylalanine decarboxylase.

Journal: PloS one 20100101

Title: Disorder in the serotonergic system due to tryptophan hydroxylation impairment: a cause of hypothalamic syndrome?

Journal: Hormone research in paediatrics 20100101

Title: Gabapentin enacarbil - clinical efficacy in restless legs syndrome.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Evaluation of toxicological and antioxidant potential of Nardostachys jatamansi in reversing haloperidol-induced catalepsy in rats.

Journal: International journal of general medicine 20100101

Title: Leigh's Disease: The Acute Clinical Course of a Two-Year-Old Child with Subacute Necrotizing Encephalomyelopathy.

Journal: Case reports in medicine 20100101

Title: Mirtazapine-associated urinary retention.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20100101

Title: Carbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson's disease.

Journal: Core evidence 20100101

Title: Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies.

Journal: PloS one 20100101

Title: Overeating Behavior and Striatal Dopamine with 6-[F]-Fluoro-L-m-Tyrosine PET.

Journal: Journal of obesity 20100101

Title: Independent component analysis of the effect of L-dopa on fMRI of language processing.

Journal: PloS one 20100101

Title: Treatment of advanced Parkinson's disease in the United States: a cost-utility model.

Journal: Clinical drug investigation 20100101

Title: [Levodopa intestinal infusion therapy in Parkinson's disease].

Journal: Neurologia i neurochirurgia polska 20100101

Title: Levodopa in the treatment of Parkinson's disease: an old drug still going strong.

Journal: Clinical interventions in aging 20100101

Title: Therapeutic interventions and adjustments in the management of Parkinson disease: role of combined carbidopa/levodopa/entacapone (Stalevo).

Journal: Neuropsychiatric disease and treatment 20100101

Title: Reducing uncertainty in value-based pricing using evidence development agreements: the case of continuous intraduodenal infusion of levodopa/carbidopa (Duodopa®) in Sweden.

Journal: Applied health economics and health policy 20100101

Title: The place of L-dopa/carbidopa in persistent vegetative state.

Journal: Clinical neuropharmacology 20100101

Title: [Pharmacotherapy of motor manifestations in late stages of Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

Title: Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson's disease.

Journal: Frontiers in systems neuroscience 20100101

Title: Treatment of advanced Parkinson's disease.

Journal: Parkinson's disease 20100101

Title: [The metabolic and molecular bases of Cockayne syndrome].

Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20100101

Title: Pharmacokinetic evaluation and modeling of formulated levodopa intranasal delivery systems.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091208

Title: Importance of membrane-bound catechol-O-methyltransferase in L-DOPA metabolism: a pharmacokinetic study in two types of Comt gene modified mice.

Journal: British journal of pharmacology 20091201

Title: Current strategies in the treatment of Parkinson's disease and a personalized approach to management.

Journal: Expert review of neurotherapeutics 20091201

Title: The U937 macrophage cell line expresses enzymatically active L-Dopa decarboxylase.

Journal: Journal of neuroimmunology 20091130

Title: The effect of memantine and levodopa/carbidopa on the responses of phrenic nerve-diaphragm preparations from aged rats.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20091101

Title: Peripheral COMT inhibition prevents levodopa associated homocysteine increase.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20091001

Title: [Perioperative management of a patient with Parkinson's disease with intravenous infusion of levodopa].

Journal: Masui. The Japanese journal of anesthesiology 20091001

Title: Pharmacokinetic-pharmacodynamic interaction between nebicapone and controlled-release levodopa/benserazide: a single-center, Phase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects.

Journal: Clinical therapeutics 20091001

Title: Managing pathological gambling in Parkinson's disease with enteral levodopa/carbidopa infusions.

Journal: Movement disorders : official journal of the Movement Disorder Society 20090915

Title: How physician obesity specialists use drugs to treat obesity.

Journal: Obesity (Silver Spring, Md.) 20090901

Title: Lack of pharmacokinetic interactions between transdermal rotigotine and oral levodopa/carbidopa.

Journal: Journal of clinical pharmacology 20090901

Title: Drug-induced compulsive behaviors: exceptions to the rule.

Journal: Mayo Clinic proceedings 20090901

Title: Growth hormone replacement therapy: transition from adolescence to adulthood.

Journal: Journal of clinical research in pediatric endocrinology 20090901

Title: Dopamine agonists in 6-pyruvoyl tetrahydropterin synthase deficiency.

Journal: Neurology 20090825

Title: [Severe kyphosis and esophagus hiatal hernia affected in the levodopa absorption of a patient with Parkinson's disease].

Journal: Rinsho shinkeigaku = Clinical neurology 20090801

Title: Pharmacokinetic-pharmacodynamic crossover comparison of two levodopa extension strategies.

Journal: Movement disorders : official journal of the Movement Disorder Society 20090715

Title: Effects of Plantago ovata husk on levodopa (with Carbidopa) bioavailability in rabbits with autonomic gastrointestinal disorders.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090701

Title: Oxidation of carbidopa by tyrosinase and its effect on murine melanoma.

Journal: Bioorganic & medicinal chemistry letters 20090701

Title: Single-dose administration of MK-0657, an NR2B-selective NMDA antagonist, does not result in clinically meaningful improvement in motor function in patients with moderate Parkinson's disease.

Journal: Journal of clinical pharmacology 20090701

Title: Levodopa/carbidopa/entacapone in Parkinson's disease.

Journal: Expert review of neurotherapeutics 20090701

Title: Disorders of biopterin metabolism.

Journal: Journal of inherited metabolic disease 20090601

Title: Kinetic characterization of the oxidation of carbidopa and benserazide by tyrosinase and peroxidase.

Journal: Bioscience, biotechnology, and biochemistry 20090601

Title: Successful management of pregnancy in a patient with Segawa disease: case report and literature review.

Journal: The journal of obstetrics and gynaecology research 20090601

Title: Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders.

Journal: International journal of molecular sciences 20090601

Title: The serotonergic system: its role in pathogenesis and early developmental treatment of autism.

Journal: Current neuropharmacology 20090601

Title: Major depressive disorder preceding the onset of progressive supranuclear palsy.

Journal: Psychiatry investigation 20090601

Title: [Long term experience with Stalevo in Szeged, Hungary].

Journal: Ideggyogyaszati szemle 20090530

Title: Comparison of pharmacokinetic profile of levodopa throughout the day between levodopa/carbidopa/entacapone and levodopa/carbidopa when administered four or five times daily.

Journal: European journal of clinical pharmacology 20090501

Title: Simultaneous kinetic-spectrofluorometric determination of levodopa and carbidopa using partial least-squares regression.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090501

Title: Restless legs syndrome.

Journal: Australian family physician 20090501

Title: Soft tissue-anchored transcutaneous port attached to an intestinal tube for long-term gastroduodenal infusion of levodopa/carbidopa in Parkinson disease.

Journal: Journal of vascular and interventional radiology : JVIR 20090401

Title: Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease.

Journal: Mayo Clinic proceedings 20090401

Title: Cyclosporine-induced parkinsonism.

Journal: Journal of neurology 20090401

Title: New drug delivery strategies for improved Parkinson's disease therapy.

Journal: Expert opinion on drug delivery 20090401

Title: Children show individual night-to-night variability of periodic limb movements in sleep.

Journal: Sleep 20090401

Title: Double-blind trial of levodopa/carbidopa/entacapone versus levodopa/carbidopa in early Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20090315

Title: Reversible Pisa syndrome in patients with Parkinson's disease on dopaminergic therapy.

Journal: Journal of neurology 20090301

Title: Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element.

Journal: International journal of molecular sciences 20090301

Title: Urodilatin and dopamine: a new interaction in the kidney.

Journal: Regulatory peptides 20090225

Title: Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report.

Journal: European journal of neurology 20090201

Title: Long-term experience with continuous duodenal levodopa-carbidopa infusion (Duodopa): report of six patients.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090201

Title: Quality of life in early Parkinson's disease treated with levodopa/carbidopa/entacapone.

Journal: Movement disorders : official journal of the Movement Disorder Society 20090115

Title: Greater motor improvement in right hemibody Parkinson's patients after dopaminergic medications.

Journal: Parkinsonism & related disorders 20090101

Title: [Continuous dopaminergic stimulation by Duodopa in advanced Parkinson's disease: Efficacy and safety].

Journal: Revue neurologique 20090101

Title: [Direct switch from conventional levodopa to stalevo (levodopa/carbidopa/entacapone) improves quality of life in Parkinson's disease: results of an open-label clinical study].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

Title: A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoni.

Journal: PloS one 20090101

Title: Levodopa/carbidopa in the treatment of amblyopia.

Journal: Journal of pediatric ophthalmology and strabismus 20090101

Title: Development and application of a high-performance liquid chromatographic method for the determination of in vitro drug release of levodopa, carbidopa, and entacapone from a tablet formulation.

Journal: Journal of AOAC International 20090101

Title: A review of ropinirole prolonged release in Parkinson's disease.

Journal: Clinical interventions in aging 20090101

Title: Pleuropulmonary Toxicity of Another Anti-Parkinson's Drug: Cabergoline.

Journal: The open respiratory medicine journal 20090101

Title: Reducing dosing frequency of carbidopa/levodopa: double-blind crossover study comparing twice-daily bilayer formulation of carbidopa/levodopa (IPX054) versus 4 daily doses of standard carbidopa/levodopa in stable Parkinson disease patients.

Journal: Clinical neuropharmacology 20090101

Title: Central levodopa influx and the clinical motor response to levodopa in patients with Parkinson disease complicated with motor fluctuations and dyskinesias.

Journal: Clinical neuropharmacology 20090101

Title: Levodopa/carbidopa/entacapone 200/50/200 mg (Stalevo 200) in the treatment of Parkinson's disease: a case series.

Journal: Cases journal 20090101

Title: Cavernous hemangioma: a rare cause for secondary parkinsonism: a case report.

Journal: The International journal of neuroscience 20090101

Title: Neural and cardiac toxicities associated with 3,4-methylenedioxymethamphetamine (MDMA).

Journal: International review of neurobiology 20090101

Title: Levodopa/carbidopa and entacapone in the treatment of Parkinson's disease: efficacy, safety and patient preference.

Journal: Patient preference and adherence 20090101

Title: Levodopa/carbidopa/entacapone-induced acute Pisa syndrome in a Parkinson's disease patient.

Journal: Journal of the neurological sciences 20081215

Title: Bilateral impairments of skilled reach-to-eat in early Parkinson's disease patients presenting with unilateral or asymmetrical symptoms.

Journal: Behavioural brain research 20081212

Title: Serum prolactin as a tool for the follow-up of treated DHPR-deficient patients.

Journal: Journal of inherited metabolic disease 20081201

Title: Case studies in the advancement of Parkinson's disease.

Journal: CNS spectrums 20081201

Title: Pharmacoscintigraphic and pharmacokinetic evaluation on healthy human volunteers of sustained-release floating minitablets containing levodopa and carbidopa.

Journal: International journal of pharmaceutics 20081119

Title: Premedication with carbidopa masks positive finding of insulinoma and beta-cell hyperplasia in [(18)F]-dihydroxy-phenyl-alanine positron emission tomography.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081110

Title: Use of the new levodopa agent Stalevo (levodopa/carbidopa/entacapone) in the treatment of Parkinson's disease in out-patient clinical practice (the START-M open trial).

Journal: Neuroscience and behavioral physiology 20081101

Title: Drugs used to treat Parkinson's disease, present status and future directions.

Journal: CNS & neurological disorders drug targets 20081001

Title: Neuropharmacology.

Journal: Indian journal of pharmacology 20081001

Title: Impact of microdialysis probes on vasculature and dopamine in the rat striatum: a combined fluorescence and voltammetric study.

Journal: Journal of neuroscience methods 20080930

Title: Lowered cAMP and cGMP signalling in the brain during levodopa-induced dyskinesias in hemiparkinsonian rats: new aspects in the pathogenetic mechanisms.

Journal: The European journal of neuroscience 20080901

Title: Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells.

Journal: Cancer research 20080901

Title: Levodopa improves procedural motor learning in chronic stroke patients.

Journal: Archives of physical medicine and rehabilitation 20080901

Title: The hydrosoluble fiber Plantago ovata husk improves levodopa (with carbidopa) bioavailability after repeated administration.

Journal: Journal of the neurological sciences 20080815

Title: Fatigue in levodopa-naive subjects with Parkinson disease.

Journal: Neurology 20080812

Title: Altered behavioural and neurochemical profile of L-DOPA following deuterium substitutions in the molecule.

Journal: Experimental neurology 20080801

Title: Response of motor complications in Cockayne syndrome to carbidopa-levodopa.

Journal: Archives of neurology 20080801

Title: Current approaches to the treatment of Parkinson's disease.

Journal: Neuropsychiatric disease and treatment 20080801

Title: Entacapone improves absorption of a coadministered salt in patients with Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20080730

Title: Simultaneous determination of levodopa and carbidopa by synchronous fluorescence spectrometry using double scans.

Journal: Analytica chimica acta 20080630

Title: Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.

Journal: Journal of psychopharmacology (Oxford, England) 20080601

Title: Did depressive symptoms affect recognition of emotional prosody in Parkinson's disease?

Journal: Neuropsychiatric disease and treatment 20080601

Title: Flow-batch technique for the simultaneous enzymatic determination of levodopa and carbidopa in pharmaceuticals using PLS and successive projections algorithm.

Journal: Talanta 20080530

Title: Innate immunity in insects: surface-associated dopa decarboxylase-dependent pathways regulate phagocytosis, nodulation and melanization in medfly haemocytes.

Journal: Immunology 20080401

Title: Dopa-responsive dystonia presenting as delayed and awkward gait.

Journal: Pediatric neurology 20080401

Title: Update on the use of pramipexole in the treatment of Parkinson's disease.

Journal: Neuropsychiatric disease and treatment 20080401

Title: Serotonergic activation after 2-week intrastriatal infusion of L-dopa and slow recovery of circling in rats with unilateral nigral lesions.

Journal: Basic & clinical pharmacology & toxicology 20080301

Title: Should levodopa dose be reduced when switched to stalevo?

Journal: European journal of neurology 20080301

Title: Levodopa improves skilled hand functions in the elderly.

Journal: The European journal of neuroscience 20080301

Title: Outcomes of 6 hour part-time occlusion treatment combined with near activities for unilateral amblyopia.

Journal: Korean journal of ophthalmology : KJO 20080301

Title: Acute overdose with controlled-release levodopa-carbidopa.

Journal: Clinical toxicology (Philadelphia, Pa.) 20080301

Title: L-dihydroxyphenylserine (Droxidopa): a new therapy for neurogenic orthostatic hypotension: the US experience.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20080301

Title: Ziprasidone for drug-induced psychotic symptoms in Parkinson's Disease.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080215

Title: Levodopa increases memory encoding and dopamine release in the striatum in the elderly.

Journal: Neurobiology of aging 20080201

Title: Drugs for Parkinson’s disease: levodopa is still the gold standard.

Journal: Neuropsychiatric disease and treatment 20080201

Title: Optimizing levodopa therapy for Parkinson's disease with levodopa/carbidopa/entacapone: implications from a clinical and patient perspective.

Journal: Neuropsychiatric disease and treatment 20080201

Title: [The use of Stalevo in Hungary for patients with Parkinson disease and its effect on the quality of life].

Journal: Ideggyogyaszati szemle 20080130

Title: Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure.

Journal: PloS one 20080101

Title: Effects of nebicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity, and motor fluctuations in patients with Parkinson disease.

Journal: Clinical neuropharmacology 20080101

Title: Enteral levodopa/carbidopa infusion in advanced Parkinson disease: long-term exposure.

Journal: Clinical neuropharmacology 20080101

Title: [Stalevo-associated lymphocytic colitis].

Journal: Gastroenterologie clinique et biologique 20080101

Title: Histamine H(3) receptor ligands modulate L-dopa-evoked behavioral responses and L-dopa derived extracellular dopamine in dopamine-denervated rat striatum.

Journal: Neurotoxicity research 20080101

Title: HIV, visceral leishmaniasis and Parkinsonism combined with diabetes mellitus and hyperuricaemia: A case report.

Journal: Cases journal 20080101

Title: [The clinical-pharmacoeconomic study of efficacy of stalevo in the treatment of Parkinson's disease with motor fluctuations].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

Title: A case of severe parkinsonism associated with short-term treatment with milnacipran.

Journal: Clinical neuropharmacology 20080101

Title: Evolution of the bioavailability and other pharmacokinetic parameters of levodopa (with carbidopa) in rabbits.

Journal: Methods and findings in experimental and clinical pharmacology 20080101

Title: Pharmacokinetic-pharmacodynamic interaction between nebicapone, a novel catechol-o-methyltransferase inhibitor, and controlled-release levodopa/carbidopa 200 mg/50 mg : randomized, double-blind, placebo-controlled, crossover study in healthy subjects.

Journal: Drugs in R&D 20080101

Title: Compensatory weight gain due to dopaminergic hypofunction: new evidence and own incidental observations.

Journal: Nutrition & metabolism 20080101

Title: Pathological hypersexuality induced by dopamine replacement therapy in a patient with progressive supranuclear palsy.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20080101

Title: Long-term L-DOPA treatment causes indiscriminate increase in dopamine levels at the cost of serotonin synthesis in discrete brain regions of rats.

Journal: Cellular and molecular neurobiology 20071201

Title: Optimizing bioavailability in the treatment of Parkinson's disease.

Journal: Neuropharmacology 20071201

Title: The neuropharmacology of (-)-stepholidine and its potential applications.

Journal: Current neuropharmacology 20071201

Title: Current concepts in the management of amblyopia.

Journal: Clinical ophthalmology (Auckland, N.Z.) 20071201

Title: Simultaneous kinetic-spectrophotometric determination of carbidopa, levodopa and methyldopa in the presence of citrate with the aid of multivariate calibration and artificial neural networks.

Journal: Analytica chimica acta 20071112

Title: Role of the pharmacist in the effective management of wearing-off in Parkinson's disease.

Journal: The Annals of pharmacotherapy 20071101

Title: [Association between amytrophic lateral sclerosis and Parkinson's disease].

Journal: Medicina clinica 20071006

Title: Investigation of the impact of sarizotan on the pharmacokinetics of levodopa.

Journal: Biopharmaceutics & drug disposition 20071001

Title: The effects of carbidopa on uptake of 6-18F-Fluoro-L-DOPA in PET of pheochromocytoma and extraadrenal abdominal paraganglioma.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20071001

Title: Pharmacological causes of hyperprolactinemia.

Journal: Therapeutics and clinical risk management 20071001

Title: Electrophysiologic changes in ventral midbrain dopaminergic neurons resulting from (+/-) -3,4-methylenedioxymethamphetamine (MDMA-'Ecstasy').

Journal: Biological psychiatry 20070915

Title: Quantification of trans-4-hydroxy-2-nonenal enantiomers and metabolites by LC-ESI-MS/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915

Title: Safety and tolerability of adjunctive tolcapone treatment in patients with early Parkinson's disease.

Journal: Journal of neurology, neurosurgery, and psychiatry 20070901

Title: Immunohistochemical detection of L-DOPA-derived dopamine within serotonergic fibers in the striatum and the substantia nigra pars reticulata in Parkinsonian model rats.

Journal: Neuroscience research 20070901

Title: Fracture risk associated with parkinsonism and anti-Parkinson drugs.

Journal: Calcified tissue international 20070901

Title: The pharmacokinetics and pharmacodynamics of levodopa in the treatment of Parkinson's disease.

Journal: Current clinical pharmacology 20070901

Title: Comment on Shpirer et al. ('Excessive daytime sleepiness in patients with Parkinson's disease: a polysomnographic study').

Journal: Movement disorders : official journal of the Movement Disorder Society 20070730

Title: Duodenal levodopa infusion for advanced Parkinson's disease: 12-month treatment outcome.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070615

Title: Simultaneous spectrophotometric determination of levodopa and carbidopa in pharmaceutical formulations and water samples by using mean centering of ratio spectra and H-point standard addition methods.

Journal: Chemical & pharmaceutical bulletin 20070601

Title: Continuous levodopa for advanced Parkinson's disease.

Journal: Neuropsychiatric disease and treatment 20070601

Title: Safety, tolerability and efficacy of levodopa-carbidopa treatment for cocaine dependence: two double-blind, randomized, clinical trials.

Journal: Drug and alcohol dependence 20070511

Title: Simultaneous kinetic determination of levodopa and carbidopa by H-point standard addition method.

Journal: Journal of pharmaceutical and biomedical analysis 20070509

Title: In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state.

Journal: Journal of neurochemistry 20070501

Title: Panic attack like episodes possibly associated with pramipexole therapy in Parkinson's disease.

Journal: European journal of neurology 20070501

Title: Acute vs chronic effects of l-dopa on bladder function in patients with mild Parkinson disease.

Journal: Neurology 20070501

Title: Duodenal levodopa infusion for the treatment of Parkinson's disease.

Journal: Expert opinion on pharmacotherapy 20070401

Title: The blood-brain barrier for catecholamines - revisited.

Journal: Neurotoxicity research 20070401

Title: Skin rash associated with Sinemet does not equal levodopa allergy.

Journal: Neurology 20070327

Title: Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism.

Journal: Brain research bulletin 20070315

Title: Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion.

Journal: Journal of psychiatry & neuroscience : JPN 20070301

Title: Nuclear imaging of neuroendocrine tumours.

Journal: Best practice & research. Clinical endocrinology & metabolism 20070301

Title: Neuropsychiatric consequences of cardiovascular medications.

Journal: Dialogues in clinical neuroscience 20070301

Title: Carbidopa/levodopa-responsive myoclonus.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070215

Title: Intravenous levodopa administration in humans based on a two-compartment kinetic model.

Journal: Journal of neuroscience methods 20070130

Title: Signaling pathways involved in atrial natriuretic factor and dopamine regulation of renal Na+, K+ -ATPase activity.

Journal: Regulatory peptides 20070110

Title: Levodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Journal: Movement disorders : official journal of the Movement Disorder Society 20070101

Title: Two cases of rapid onset Parkinson's syndrome following toxic ingestion of ethylene glycol and methanol.

Journal: Clinical pharmacology and therapeutics 20070101

Title: Cerebral folate deficiency and folinic acid treatment in hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC) syndrome.

Journal: The Tohoku journal of experimental medicine 20070101

Title: Clinical efficacy of a single afternoon dose of effervescent levodopa-carbidopa preparation (CHF 1512) in fluctuating Parkinson disease.

Journal: Clinical neuropharmacology 20070101

Title: Comparison of 200 mg retarded release levodopa/carbidopa - with 150 mg levodopa/carbidopa/entacapone application: pharmacokinetics and efficacy in patients with Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070101

Title: High prevalence of extrapyramidal signs and symptoms in a group of Italian dental technicians.

Journal: BMC neurology 20070101

Title: Entacapone prolongs the reduction of PLM by levodopa/carbidopa in restless legs syndrome.

Journal: Clinical neuropharmacology 20070101

Title: Simultaneous determination of levodopa and carbidopa in levodopa-carbidopa tablets by ATR-FTIR spectrometry.

Journal: Pharmaceutical development and technology 20070101

Title: [The study on the assessment of the new levodopa drug--stalevo (levodopa/carbidopa/entacapone), in treatment of Parkinson's disease in out-patient clinical practice (the results of the open START-M)].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

Title: PET 6-[F]fluoro-L-m-tyrosine Studies of Dopaminergic Function in Human and Nonhuman Primates.

Journal: Frontiers in human neuroscience 20070101

Title: Pharmacologic management of Parkinson's disease in long-term care residents: maintaining functionality to improve quality of life.

Journal: Director (Cincinnati, Ohio) 20070101

Title: [Prevention and treatment of fluctuations in patients with Parkinson's disease].

Journal: Praxis 20061220

Title: Dopamine agonist therapy for Parkinson disease and pathological gambling.

Journal: Parkinsonism & related disorders 20061201

Title: Outcome prediction of enteral levodopa/carbidopa infusion in advanced Parkinson's disease.

Journal: Parkinsonism & related disorders 20061201

Title: Utility of tolcapone in fluctuating Parkinson's disease.

Journal: Clinical interventions in aging 20061201

Title: Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study.

Journal: Neurology 20061114

Title: Cardiovascular responses to combined treatment with selective monoamine oxidase type B inhibitors and L-DOPA in the rat.

Journal: British journal of pharmacology 20061101

Title: D-dopa is unidirectionally converted to L-dopa by D-amino acid oxidase, followed by dopa transaminase.

Journal: Clinical and experimental pharmacology & physiology 20061101

Title: Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy.

Journal: Pediatric neurology 20061101

Title: Pharmacokinetic behaviour of levodopa and 3-O-methyldopa after repeat administration of levodopa/carbidopa with and without entacapone in patients with Parkinson's disease.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20061001

Title: Symptomatic treatment in the fragile X-associated tremor/ataxia syndrome.

Journal: Movement disorders : official journal of the Movement Disorder Society 20061001

Title: Levodopa can worsen tremor associated with dystonia.

Journal: Movement disorders : official journal of the Movement Disorder Society 20061001

Title: Noradrenaline is necessary for the hedonic properties of addictive drugs.

Journal: Vascular pharmacology 20061001

Title: Parkinsonism-hyperpyrexia syndrome: the role of electroconvulsive therapy.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20061001

Title: Enteral levodopa/carbidopa gel infusion for the treatment of motor fluctuations and dyskinesias in advanced Parkinson's disease.

Journal: Expert review of neurotherapeutics 20061001

Title: Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20060901

Title: OFF-off rebound dyskinesia in subthalamic nucleus deep brain stimulation of Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060901

Title: Patient satisfaction with switching to Stalevo: an open-label evaluation in PD patients experiencing wearing-off (Simcom Study).

Journal: Acta neurologica Scandinavica 20060901

Title: Staging of carcinoid tumours with 18F-DOPA PET: a prospective, diagnostic accuracy study.

Journal: The Lancet. Oncology 20060901

Title: Long-term care of Parkinson's disease. Strategies for managing 'wearing off' symptom re-emergence and dyskinesias.

Journal: Geriatrics 20060901

Title: Part-time occlusion therapy for anisometropic amblyopia detected in children eight years of age and older.

Journal: Korean journal of ophthalmology : KJO 20060901

Title: Understanding Parkinson's disease: an update on current diagnostic and treatment strategies.

Journal: Journal of the American Medical Directors Association 20060901

Title: Effects of subchronic treatment with selegiline on L-DOPA-induced increase in extracellular dopamine level in rat striatum.

Journal: Journal of pharmacological sciences 20060801

Title: Broadening the phenotype of childhood-onset dopa-responsive dystonia.

Journal: Archives of neurology 20060801

Title: The levodopa wearing-off phenomenon in Parkinson's disease: pharmacokinetic considerations.

Journal: Expert opinion on pharmacotherapy 20060701

Title: The effect of levodopa or levodopa-carbidopa (sinemet) on fracture healing.

Journal: Journal of orthopaedic trauma 20060701

Title: Spinal myoclonus following combined spinal-epidural anaesthesia for Caesarean section.

Journal: Anaesthesia 20060601

Title: Effective treatment with levodopa and carbidopa for hypomyelination with atrophy of the basal ganglia and cerebellum.

Journal: The Tohoku journal of experimental medicine 20060601

Title: [Case of juvenile parkinsonism in pregnancy].

Journal: Rinsho shinkeigaku = Clinical neurology 20060601

Title: Restless legs syndrome: diagnosis and review of management options.

Journal: Neuropsychiatric disease and treatment 20060601

Title: Modified high-performance liquid chromatography with electrochemical detection method for plasma measurement of levodopa, 3-O-methyldopa, dopamine, carbidopa and 3,4-dihydroxyphenyl acetic acid.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060519

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Psychiatric sequelae of Parkinson disease: a case report.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20060401

Title: Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan.

Journal: Pharmacology & therapeutics 20060301

Title: Inhibition of catechol-O-methyltransferase contributes to more stable levodopa plasma levels.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060301

Title: Quantitative structure-pharmacokinetic relationships for drug clearance by using statistical learning methods.

Journal: Journal of molecular graphics & modelling 20060301

Title: Congenital hyperinsulinism: pancreatic [18F]fluoro-L-dihydroxyphenylalanine (DOPA) positron emission tomography and immunohistochemistry study of DOPA decarboxylase and insulin secretion.

Journal: The Journal of clinical endocrinology and metabolism 20060301

Title: Familial dopa-responsive cervical dystonia.

Journal: Neurology 20060227

Title: Augmentation of artistic productivity in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060201

Title: A randomized controlled trial of etilevodopa in patients with Parkinson disease who have motor fluctuations.

Journal: Archives of neurology 20060201

Title: Effects of deep brain stimulation and medication on strength, bradykinesia, and electromyographic patterns of the ankle joint in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060101

Title: Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography.

Journal: European journal of nuclear medicine and molecular imaging 20060101

Title: Hemiparkinsonism with a discrete lacunar infarction in the contralateral substantia nigra.

Journal: Movement disorders : official journal of the Movement Disorder Society 20060101

Title: Electroconvulsive therapy for the treatment of multiple system atrophy with major depression.

Journal: General hospital psychiatry 20060101

Title: Motor deficits in Parkinsonian reaching: dopa-sensitivity influenced by real-world task constraint.

Journal: Journal of motor behavior 20060101

Title: Conversion from sustained release carbidopa/levodopa to carbidopa/levodopa/entacapone (stalevo) in Parkinson disease patients.

Journal: Clinical neuropharmacology 20060101

Title: Recognition and treatment of Alzheimer's disease: a case-based review.

Journal: American journal of Alzheimer's disease and other dementias 20060101

Title: [Dopamine receptors agonists (mirapex) in the treatment of Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

Title: The discovery of the pressor effect of DOPS and its blunting by decarboxylase inhibitors.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Motor fluctuations in Parkinson's disease.

Journal: Reviews in neurological diseases 20060101

Title: [Stalevo (levodopa/carbidopa/entacapon)--a new generation drug in the treatment of Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

Title: Osmotic demyelination and hypertonic dehydration in a 9-year-old girl: changes in cerebrospinal fluid myelin basic protein.

Journal: Journal of intensive care medicine 20060101

Title: Altered pattern of brain dopamine synthesis in male adolescents with attention deficit hyperactivity disorder.

Journal: Behavioral and brain functions : BBF 20060101

Title: L-Dihydroxyphenylserine (L-DOPS): a norepinephrine prodrug.

Journal: Cardiovascular drug reviews 20060101

Title: Nonarteritic anterior ischemic optic neuropathy.

Journal: Current opinion in ophthalmology 20051201

Title: Absorption of orally disintegrating carbidopa-levodopa requires intact small bowel function.

Journal: Neurology 20051108

Title: [Continuous treatment with levodopa of Parkinson disease].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20051006

Title: Hydrosoluble fiber (Plantago ovata husk) and levodopa II: experimental study of the pharmacokinetic interaction in the presence of carbidopa.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051001

Title: Enantioselective metabolism of trans-4-hydroxy-2-nonenal by brain mitochondria.

Journal: Free radical biology & medicine 20051001

Title: Does levodopa slow or hasten the rate of progression of Parkinson's disease?

Journal: Journal of neurology 20051001

Title: Effects of levodopa oral bolus on the kinematics of the pointing movements in Parkinson's disease patients.

Journal: Journal of neurology 20050901

Title: The effects of a selective dopamine D2 receptor agonist on behavioral and pathological outcome in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated squirrel monkeys.

Journal: The Journal of pharmacology and experimental therapeutics 20050901

Title: Reverse Shapiro's syndrome--an unusual cause of fever of unknown origin.

Journal: Brain & development 20050901

Title: Mood fluctuations in Parkinson's disease: a pilot study comparing the effects of intravenous and oral levodopa administration.

Journal: Neuropsychiatric disease and treatment 20050901

Title: Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.

Journal: PLoS biology 20050801

Title: Importance of within subject variation in levodopa pharmacokinetics: a 4 year cohort study in Parkinson's disease.

Journal: Journal of pharmacokinetics and pharmacodynamics 20050801

Title: 6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.

Journal: Annals of neurology 20050701

Title: Cost-effectiveness of levodopa/carbidopa/entacapone (Stalevo) compared to standard care in UK Parkinson's disease patients with wearing-off.

Journal: Current medical research and opinion 20050701

Title: [Advanced course of Parkinson disease. Little improved motion with continuous intestinal levodopa administration].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20050701

Title: Persistence of hyperprolactinemia after treatment of primary hypothyroidism and withdrawal of long term use of estrogen: are the tuberoinfundibular dopaminergic neurons permanently lesioned?

Journal: Arquivos brasileiros de endocrinologia e metabologia 20050601

Title: [Optimization of use of levodopa in Parkinson's disease: role of levodopa-carbidopa-entacapone combination].

Journal: Neurologia (Barcelona, Spain) 20050501

Title: The effect of entacapone on homocysteine levels in Parkinson disease.

Journal: Neurology 20050426

Title: Hydrogen peroxide degradation and selective carbidopa-induced cytotoxicity against human tumor lines.

Journal: Biochemical pharmacology 20050415

Title: [18F]FDOPA PET and clinical features in parkinsonism due to manganism.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050401

Title: Levodopa + carbidopa + entacapone. Entacapone: a second look: new preparations. Parkinson's disease: a modest effect.

Journal: Prescrire international 20050401

Title: Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug-naive primates.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050301

Title: Levodopa challenge neuroimaging of levodopa-related mood fluctuations in Parkinson's disease.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301

Title: Randomized controlled pilot trial of cabergoline, hydergine and levodopa/carbidopa: Los Angeles Cocaine Rapid Efficacy Screening Trial (CREST).

Journal: Addiction (Abingdon, England) 20050301

Title: Correlation between acoustic speech characteristics and non-speech motor performance in Parkinson Disease.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20050301

Title: Efficacy of levodopa and carbidopa on visual function in patients with non-arteritic anterior ischaemic optic neuropathy.

Journal: International journal of clinical practice 20050301

Title: Carbidopa/levodopa-loaded biodegradable microspheres: in vivo evaluation on experimental Parkinsonism in rats.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050216

Title: Actions of methylphenidate on dopaminergic neurons of the ventral midbrain.

Journal: Biological psychiatry 20050215

Title: An open-label evaluation of the tolerability and safety of Stalevo (carbidopa, levodopa and entacapone) in Parkinson's disease patients experiencing wearing-off.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050201

Title: Parcopa: a rapidly dissolving formulation of carbidopa/levodopa.

Journal: The Medical letter on drugs and therapeutics 20050131

Title: An intermittent, controlled-rate, slow progressive degeneration model of Parkinson's disease: antiparkinson effects of Sinemet and protective effects of methylphenidate.

Journal: Behavioural brain research 20050130

Title: Duodenal levodopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease.

Journal: Neurology 20050125

Title: I couldn't sleep at all last night.

Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20050115

Title: Dopamine agonist cabergoline inhibits levodopa-induced caspase activation in 6-OHDA-lesioned mice.

Journal: Neuroscience research 20050101

Title: A multicenter, open-label, sequential study comparing preferences for carbidopa-levodopa orally disintegrating tablets and conventional tablets in subjects with Parkinson's disease.

Journal: Clinical therapeutics 20050101

Title: Signal transduction pathways of nitric oxide release in primary microglial culture challenged with gram-positive bacterial constituent, lipoteichoic acid.

Journal: Neuroscience 20050101

Title: Entacapone increases levodopa exposure and reduces plasma levodopa variability when used with Sinemet CR.

Journal: Clinical neuropharmacology 20050101

Title: Treatment of end-of-dose wearing-off in parkinson's disease: stalevo (levodopa/carbidopa/entacapone) and levodopa/DDCI given in combination with Comtess/Comtan (entacapone) provide equivalent improvements in symptom control superior to that of traditional levodopa/DDCI treatment.

Journal: European neurology 20050101

Title: Effects of donepezil on compulsive hypersexual behavior in Parkinson disease: a single case study.

Journal: American journal of therapeutics 20050101

Title: Levodopa and the progression of Parkinson's disease.

Journal: The New England journal of medicine 20041209

Title: Levodopa with carbidopa diminishes glycogen concentration, glycogen synthase activity, and insulin-stimulated glucose transport in rat skeletal muscle.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20041201

Title: Pathophysiology of parkinsonism due to hydrocephalus.

Journal: Journal of neurology, neurosurgery, and psychiatry 20041101

Title: Concurrent administration of donepezil HCl and levodopa/carbidopa in patients with Parkinson's disease: assessment of pharmacokinetic changes and safety following multiple oral doses.

Journal: British journal of clinical pharmacology 20041101

Title: Differential time and related appearance of signs, indicating improvement in the state of consciousness in vegetative state traumatic brain injury (VS-TBI) patients after initiation of dopamine treatment.

Journal: Brain injury 20041101

Title: Clinical advantages of COMT inhibition with entacapone - a review.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20041001

Title: Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy.

Journal: Brain research 20041001

Title: Effect of monoamine reuptake inhibitor NS 2330 in advanced Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20041001

Title: Superficial siderosis of the central nervous system associated with parkinsonism.

Journal: Parkinsonism & related disorders 20041001

Title: Pyruvate dehydrogenase deficiency presenting as dystonia in childhood.

Journal: Developmental medicine and child neurology 20041001

Title: Double-blind, placebo-controlled study of entacapone in levodopa-treated patients with stable Parkinson disease.

Journal: Archives of neurology 20041001

Title: A young onset Parkinson's patient: a case study.

Journal: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20041001

Title: Delayed administration may improve entacapone effects in parkinsonian patients non-responding to the drug.

Journal: European journal of neurology 20040901

Title: Drug treatment of Parkinson's disease.

Journal: Dialogues in clinical neuroscience 20040901

Title: Dopaminergic modulation of response inhibition: an fMRI study.

Journal: Brain research. Cognitive brain research 20040801

Title: Circadian effects of dopaminergic treatment in restless legs syndrome.

Journal: Sleep medicine 20040701

Title: IR, UV-Vis, magnetic and thermal characterization of chelates of some catecholamines and 4-aminoantipyrine with Fe(III) and Cu(II).

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701

Title: Markedly asymmetrical parkinsonism as a leading feature of adult-onset Huntington's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040701

Title: Clinical experience with the novel levodopa formulation entacapone + levodopa + carbidopa (Stalevo).

Journal: Expert review of neurotherapeutics 20040701

Title: Circadian variation in neuroendocrine response to L-dopa in patients with restless legs syndrome.

Journal: Sleep 20040615

Title: Novel dopamine releasing response of an anti-convulsant agent with possible anti-Parkinson's activity.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040601

Title: Severe multivalvular heart disease: a new complication of the ergot derivative dopamine agonists.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040601

Title: Temporal administration of entacapone with slow release L-dopa: pharmacokinetic profile and clinical outcome.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20040601

Title: Modeling the short- and long-duration responses to exogenous levodopa and to endogenous levodopa production in Parkinson's disease.

Journal: Journal of pharmacokinetics and pharmacodynamics 20040601

Title: [Diagnosis and treatment of parkinsonian syndrome].

Journal: MMW Fortschritte der Medizin 20040524

Title: Stalevo for Parkinson's disease.

Journal: The Medical letter on drugs and therapeutics 20040510

Title: Inhibitory effects of trace amines on rat midbrain dopaminergic neurons.

Journal: Neuropharmacology 20040501

Title: Loss of D3 receptors in the zitter mutant rat is not reversed by L-dopa treatment.

Journal: Experimental neurology 20040501

Title: Drug adherence in Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040501

Title: PET in the diagnosis of neuroendocrine tumors.

Journal: Annals of the New York Academy of Sciences 20040401

Title: Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis.

Journal: European journal of pharmacology 20040319

Title: Investigating the potential of erythromycin and derivatives as chiral selector in capillary electrophoresis.

Journal: Journal of pharmaceutical and biomedical analysis 20040310

Title: Levodopa-responsive aromatic L-amino acid decarboxylase deficiency.

Journal: Annals of neurology 20040301

Title: Delayed postanoxic encephalopathy: a case report and literature review.

Journal: Archives of physical medicine and rehabilitation 20040301

Title: Apraxia of lid opening: dose-dependent response to carbidopa-levodopa.

Journal: Pharmacotherapy 20040301

Title: Overexpression of dopa decarboxylase in peritoneal dissemination of gastric cancer and its potential as a novel marker for the detection of peritoneal micrometastases with real-time RT-PCR.

Journal: British journal of cancer 20040209

Title: Split spinal cord malformation in an elderly patient: case report.

Journal: Surgical neurology 20040201

Title: Entacapone improves the pharmacokinetic and therapeutic response of controlled release levodopa/carbidopa in Parkinson's patients.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20040201

Title: Exercise-induced dystonia as a preceding symptom of familial Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040201

Title: Levodopa/carbidopa/entacapone (Stalevo).

Journal: Neurology 20040113

Title: The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040101

Title: Quality of life in early Parkinson's disease: impact of dyskinesias and motor fluctuations.

Journal: Movement disorders : official journal of the Movement Disorder Society 20040101

Title: Time profile of cerebral [18F]6-fluoro-L-DOPA metabolites in nonhuman primate: implications for the kinetics of therapeutic L-DOPA.

Journal: Frontiers in bioscience : a journal and virtual library 20040101

Title: Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/carbidopa.

Journal: Clinical neuropharmacology 20040101

Title: [Effect of cerebrolysin on the electroencephalographic indices of brain activity in Parkinson's disease].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

Title: The effect of ascorbic acid on the pharmacokinetics of levodopa in elderly patients with Parkinson disease.

Journal: Clinical neuropharmacology 20040101

Title: [Treatment of non-arterial ischemic anterior optic neuropathy. Clinical study].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101

Title: [Use of tremonorm in treatment of Parkinson's disease: outpatient experience of Moscow Municipal Health Care Service].

Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

Title: Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice.

Journal: Pharmacology, biochemistry, and behavior 20031201

Title: Treatment of seasonal affective disorders.

Journal: Dialogues in clinical neuroscience 20031201

Title: Toxic pediatric parkinsonism: report of a child with metabolic studies and response to treatment.

Journal: Journal of child neurology 20031101

Title: FK506 as effective adjunct to L-dopa in reserpine-induced catalepsy in rats.

Journal: Indian journal of experimental biology 20031101

Title: Norepinephrine precursor therapy in neurogenic orthostatic hypotension.

Journal: Circulation 20030812

Title: Adenosine A(2A) receptor antagonist treatment of Parkinson's disease.

Journal: Neurology 20030812

Title: L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030801

Title: The CB1 cannabinoid receptor agonist, HU-210, reduces levodopa-induced rotations in 6-hydroxydopamine-lesioned rats.

Journal: Pharmacology & toxicology 20030801

Title: Adverse effects of subthalamic nucleus DBS in a patient with multiple system atrophy.

Journal: Neurology 20030722

Title: Rapid intravenous loading of levodopa for human research: clinical results.

Journal: Journal of neuroscience methods 20030715

Title: L-DOPA supply to the neuro retina activates dopaminergic communication at the early stages of embryonic development.

Journal: Journal of neurochemistry 20030701

Title: Crossover study of (99m)Tc-TRODAT-1 SPECT and (18)F-FDOPA PET in Parkinson's disease patients.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030701

Title: Quercetin potentiates L-Dopa reversal of drug-induced catalepsy in rats: possible COMT/MAO inhibition.

Journal: Pharmacology 20030601

Title: [Pharmacokinetic comparison of Sinemet and Grifoparkin (levodopa/carbidopa 250/25 mg) in Parkinson s disease: a single dose study].

Journal: Revista medica de Chile 20030601

Title: Effect of pulsatile administration of levodopa on dyskinesia induction in drug-naïve MPTP-treated common marmosets: effect of dose, frequency of administration, and brain exposure.

Journal: Movement disorders : official journal of the Movement Disorder Society 20030501

Title: Randomized trial of pallidotomy versus medical therapy for Parkinson's disease.

Journal: Annals of neurology 20030501

Title: Viral encephalitis complicated by neuroleptic malignant syndrome in a 7-year-old girl.

Journal: Pediatric emergency care 20030401

Title: Selegiline in the treatment of Parkinson's disease: its impact on orthostatic hypotension.

Journal: Parkinsonism & related disorders 20030301

Title: Commonly used L-amino acid decarboxylase inhibitors block monoamine oxidase activity in the rat.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20030301

Title: Novel levodopa gastroretentive dosage form: in-vivo evaluation in dogs.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030214

Title: Reversal of parkinsonism following liver transplantation.

Journal: Neurology 20030211

Title: Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells.

Journal: The Journal of biological chemistry 20030207

Title: Leg muscle strength is reduced in Parkinson's disease and relates to the ability to rise from a chair.

Journal: Movement disorders : official journal of the Movement Disorder Society 20030201

Title: Neonatal dopa-responsive extrapyramidal syndrome in twins with recessive GTPCH deficiency.

Journal: Neurology 20030128

Title: Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat.

Journal: Neurochemistry international 20030101

Title: Parkinsonian speech disfluencies: effects of L-dopa-related fluctuations.

Journal: Journal of fluency disorders 20030101

Title: Optimizing levodopa pharmacokinetics: intestinal infusion versus oral sustained-release tablets.

Journal: Clinical neuropharmacology 20030101

Title: [Respiratory regulation during adaptation to intermittent hypoxia in patients with Parkinson disease].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101

Title: Entacapone/levodopa/carbidopa combination tablet: Stalevo.

Journal: Drugs in R&D 20030101

Title: Pharmacokinetics of etilevodopa compared to levodopa in patients with Parkinson's disease: an open-label, randomized, crossover study.

Journal: Clinical neuropharmacology 20030101

Title: Effect of promoters on cellular immune response induced by recombinant fowlpox virus expressing multi-epitope polypeptides from HIV-1.

Journal: Biotechnology and applied biochemistry 20021201

Title: Levodopa-carbidopa with occlusion in older children with amblyopia.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20021201

Title: Semicarbazide-sensitive amine oxidase (SSAO) gene expression in alloxan-induced diabetes in mice.

Journal: Molecular medicine (Cambridge, Mass.) 20021201

Title: Levodopa but not ropinirole induces an internalization of D1 dopamine receptors in parkinsonian rats.

Journal: Movement disorders : official journal of the Movement Disorder Society 20021101

Title: Clozapine withdrawal symptoms in a Parkinson's disease patient.

Journal: Movement disorders : official journal of the Movement Disorder Society 20021101

Title: Effects of entacapone and tolcapone on mitochondrial membrane potential.

Journal: European journal of pharmacology 20021018

Title: Entacapone improves the availability of L-dopa in plasma by decreasing its peripheral metabolism independent of L-dopa/carbidopa dose.

Journal: British journal of clinical pharmacology 20021001

Title: Dopamine replacement therapy reverses abnormal synchronization of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine primate model of parkinsonism.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915

Title: Olanzapine: a proarrhythmic drug?

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020901

Title: Repeated administration of piribedil induces less dyskinesia than L-dopa in MPTP-treated common marmosets: a behavioural and biochemical investigation.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020901

Title: Quantitative description of loss of clinical benefit following withdrawal of levodopa-carbidopa and bromocriptine in early Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020901

Title: Simultaneous determination of dopa and carbidopa enantiomers by capillary zone electrophoresis.

Journal: Electrophoresis 20020901

Title: The role of PET in localization of neuroendocrine and adrenocortical tumors.

Journal: Annals of the New York Academy of Sciences 20020901

Title: [Hallucinations caused by paroxetine taken together with a levodopa-carbidopa preparation].

Journal: Nederlands tijdschrift voor geneeskunde 20020831

Title: Acute dopaminergic challenge tests to assess postural/kinetic tremor of different origin: a case report.

Journal: Journal of neurology, neurosurgery, and psychiatry 20020801

Title: Two advances in the management of Parkinson disease.

Journal: Cleveland Clinic journal of medicine 20020801

Title: Selegiline: a second look. Six years later: too risky in Parkinson's disease.

Journal: Prescrire international 20020801

Title: [The usefulness of dopaminergic drugs in traumatic brain injury].

Journal: Revista de neurologia 20020801

Title: Role of adenosine in drug-induced catatonia in mice.

Journal: Indian journal of experimental biology 20020801

Title: Levodopa-responsive rubral (Holmes') tremor.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020701

Title: In vivo metabolism and partitioning of 6-[18F]fluoro-L-meta-tyrosine in whole blood: a unified compartment model.

Journal: Physics in medicine and biology 20020607

Title: [Hallucinations caused by paroxetine in combined usage of levodopa-carbidopa].

Journal: Nederlands tijdschrift voor geneeskunde 20020601

Title: Gateways to Clinical Trials. June 2002.

Journal: Methods and findings in experimental and clinical pharmacology 20020601

Title: Role of sphingosine synthesis inhibition in transcutaneous delivery of levodopa.

Journal: International journal of pharmaceutics 20020515

Title: Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics.

Journal: Neurology 20020514

Title: Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition.

Journal: Molecular pharmacology 20020401

Title: Placebo-controlled comparison of three dose-regimens of 5-hydroxytryptophan challenge test in healthy volunteers.

Journal: Journal of clinical psychopharmacology 20020401

Title: [Serotonin syndrome: report of a fatal case and review of the literature].

Journal: Revista clinica espanola 20020401

Title: [Hallucinations caused by paroxetine taken together with a levodopa-carbidopa preparation].

Journal: Nederlands tijdschrift voor geneeskunde 20020323

Title: Influence of layer position on in vitro and in vivo release of levodopa methyl ester and carbidopa from three-layer matrix tablets.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020301

Title: Parkinson's disease. Therapeutic strategies to improve patient function and quality of life.

Journal: Geriatrics 20020301

Title: Oral solution of levodopa ethylester for treatment of response fluctuations in patients with advanced Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020301

Title: Entacapone in restless legs syndrome.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020301

Title: Bruxism as presenting feature of Parkinson's disease.

Journal: The Journal of the Association of Physicians of India 20020301

Title: Parkinsonism associated with interferon alpha therapy for chronic myelogenous leukemia.

Journal: Hawaii medical journal 20020301

Title: Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa.

Journal: The Annals of pharmacotherapy 20020201

Title: [Benefit of L-DOPA-without-DCI (decarboxylase inhibitor) therapy on wearing-off phenomenon in advanced stages of Parkinson's disease patients].

Journal: No to shinkei = Brain and nerve 20020201

Title: Screening for tetrahydrobiopterin deficiency among hyperphenylalaninemia patients in Southern China.

Journal: Chinese medical journal 20020201

Title: Parkinson disease neuropathology: later-developing dementia and loss of the levodopa response.

Journal: Archives of neurology 20020101

Title: Chronic high dose L-DOPA alone or in combination with the COMT inhibitor entacapone does not increase oxidative damage or impair the function of the nigro-striatal pathway in normal cynomologus monkeys.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020101

Title: Life-threatening parkinsonism induced by kava-kava.

Journal: Movement disorders : official journal of the Movement Disorder Society 20020101

Title: Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.

Journal: The European journal of neuroscience 20020101

Title: The SSRI, citalopram, improves bradykinesia in patients with Parkinson's disease treated with L-dopa.

Journal: Clinical neuropharmacology 20020101

Title: A double-blind crossover, placebo-controlled study of the adenosine A2A antagonist theophylline in Parkinson's disease.

Journal: Clinical neuropharmacology 20020101

Title: Levodopa plus carbidopa before physiotherapy increased motor recovery after stroke.

Journal: ACP journal club 20020101

Title: Effect of levodopa and carbidopa in human amblyopia.

Journal: Journal of pediatric ophthalmology and strabismus 20020101

Title: Dopaminergic transmission in the rat striatum in vivo in conditions of pharmacological modulation.

Journal: Neuroscience and behavioral physiology 20020101

Title: Nitecapone and selegiline as effective adjuncts to L-DOPA in reserpine-induced catatonia in mice.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: [The use of amantadine sulfate in combined therapy of Parkinson's disease].

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Title: [Rhabdomyolysis as a complication of Parkinson's disease].

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Tags:28860-95-9 Molecular Formula|28860-95-9 MDL|28860-95-9 SMILES|28860-95-9 3,3,3-trideuterio-2-[dideuterio-(3,4-dihydroxyphenyl)methyl]-2-hydrazinylpropanoic acid