Title: Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B.
Journal: Chemico-biological interactions 20171225
Title: A novel topoisomerase 2a inhibitor, cryptotanshinone, suppresses the growth of PC3 cells without apparent cytotoxicity.
Journal: Toxicology and applied pharmacology 20170901
Title: Cryptotanshinone induces ROS-dependent autophagy in multidrug-resistant colon cancer cells.
Journal: Chemico-biological interactions 20170801
Title: Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells.
Journal: Archives of toxicology 20160901
Title: Effects of tanshinones from Salvia miltiorrhiza on CYP2C19 activity in human liver microsomes: enzyme kinetic and molecular docking studies.
Journal: Chemico-biological interactions 20150325
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases.
Journal: Bioorganic & medicinal chemistry 20121001
Title: Cryptotanshinone down-regulates androgen receptor signaling by modulating lysine-specific demethylase 1 function.
Journal: International journal of cancer 20120915
Title: Cryptotanshinone attenuates isoprenaline-induced cardiac fibrosis in mice associated with upregulation and activation of matrix metalloproteinase-2.
Journal: Molecular medicine reports 20120701
Title: Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.
Journal: Pharmaceutical research 20120601
Title: The selective inhibitory effect of a synthetic tanshinone derivative on prostate cancer cells.
Journal: The Prostate 20120515
Title: Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells.
Journal: Cancer prevention research (Philadelphia, Pa.) 20120501
Title: Cryptotanshinione inhibits β-amyloid aggregation and protects damage from β-amyloid in SH-SY5Y cells.
Journal: Neurochemical research 20120301
Title: Cryptotanshinone induces ER stress-mediated apoptosis in HepG2 and MCF7 cells.
Journal: Apoptosis : an international journal on programmed cell death 20120301
Title: Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells.
Journal: Cancer letters 20120301
Title: Production of salvianolic acid B in roots of Salvia miltiorrhiza (Danshen) during the post-harvest drying process.
Journal: Molecules (Basel, Switzerland) 20120227
Title: Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115
Title: ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide.
Journal: Bioorganic & medicinal chemistry letters 20111215
Title: Development of a strategy and process parameters for a green process in counter-current chromatography: purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study.
Journal: Journal of chromatography. A 20110909
Title: Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice.
Journal: International journal of cancer 20110901
Title: In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.
Journal: Bioorganic & medicinal chemistry 20110815
Title: Flavans from Iris tenuifolia and their effects on β-amyloid aggregation and neural stem cells proliferation in vitro.
Journal: Bioorganic & medicinal chemistry letters 20110801
Title: Ultrasonication-assisted extraction and preconcentration of medicinal products from herb by ionic liquids.
Journal: Talanta 20110715
Title: Cryptotanshinone has diverse effects on cell cycle events in melanoma cell lines with different metastatic capacity.
Journal: Cancer chemotherapy and pharmacology 20110701
Title: Cryptotanshinone enhances TNF-α-induced apoptosis in chronic myeloid leukemia KBM-5 cells.
Journal: Apoptosis : an international journal on programmed cell death 20110701
Title: [Impact of Cryptotanshinone on the reproductivity and metabolism of male mice with Akt2 deletion].
Journal: Zhonghua nan ke xue = National journal of andrology 20110701
Title: Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship.
Journal: Fitoterapia 20110601
Title: Cryptotanshinone reverses reproductive and metabolic disturbances in prenatally androgenized rats via regulation of ovarian signaling mechanisms and androgen synthesis.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110401
Title: Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.
Journal: Toxicology and applied pharmacology 20110401
Title: Plant density-dependent variations in bioactive markers and root yield in Australian-grown Salvia miltiorrhiza Bunge.
Journal: Chemistry & biodiversity 20110401
Title: Molecular imprinting in ionic liquid-modified porous polymer for recognitive separation of three tanshinones from Salvia miltiorrhiza Bunge.
Journal: Analytical and bioanalytical chemistry 20110301
Title: Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20101201
Title: [Formulation study on cryptotanshinone gel for topical administration].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101201
Title: Simultaneous determination of danshensu, rosmarinic acid, cryptotanshinone, tanshinone IIA, tanshinone I and dihydrotanshinone I by liquid chromatographic-mass spectrometry and the application to pharmacokinetics in rats.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: [Absorption mechanism of tanshinone II A, cryptotanshinone, tanshinone I and tanshinones extract in rat small intestine in vivo].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
Title: [Effects of combination of Salvia miltiorrhiza and Panax notoginseng on the pharmacokinetics of their major bioactive components in Beagle dog].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101101
Title: Interaction study of two diterpenes, cryptotanshinone and dihydrotanshinone, to human acetylcholinesterase and butyrylcholinesterase by molecular docking and kinetic analysis.
Journal: Chemico-biological interactions 20100906
Title: Synthesis and vasodilative activity of tanshinone IIA derivatives.
Journal: Bioorganic & medicinal chemistry letters 20100815
Title: Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation.
Journal: Cancer prevention research (Philadelphia, Pa.) 20100801
Title: Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells.
Journal: Journal of natural products 20100528
Title: Cryptotanshinone, an acetylcholinesterase inhibitor from Salvia miltiorrhiza, ameliorates scopolamine-induced amnesia in Morris water maze task.
Journal: Planta medica 20100201
Title: Ionic liquid surfactant-mediated ultrasonic-assisted extraction coupled to HPLC: application to analysis of tanshinones in Salvia miltiorrhiza bunge.
Journal: Journal of separation science 20091201
Title: Reactive oxygen species-mediated kinase activation by dihydrotanshinone in tanshinones-induced apoptosis in HepG2 cells.
Journal: Cancer letters 20091118
Title: Proliferative inhibition of danxiongfang and its active ingredients on rat vascular smooth muscle cell and protective effect on the VSMC damage induced by hydrogen peroxide.
Journal: Journal of ethnopharmacology 20091112
Title: Preventive effects of a purified extract isolated from Salvia miltiorrhiza enriched with tanshinone I, tanshinone IIA and cryptotanshinone on hepatocyte injury in vitro and in vivo.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091101
Title: HPLC profiles and biomarker contents of Australian-grown Salvia miltiorrhiza f. alba roots.
Journal: Chemistry & biodiversity 20090701
Title: Seasonal variations in bioactive marker contents in Australian-grown Salvia miltiorrhiza roots.
Journal: Chemistry & biodiversity 20090401
Title: Cryptotanshinone protects primary rat cortical neurons from glutamate-induced neurotoxicity via the activation of the phosphatidylinositol 3-kinase/Akt signaling pathway.
Journal: Experimental brain research 20090201
Title: Cultivar variations of Australian-grown Danshen (Salvia miltiorrhiza): bioactive markers and root yields.
Journal: Chemistry & biodiversity 20090201
Title: PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
Journal: Chemico-biological interactions 20090115
Title: Salvia miltiorrhiza Bunge and its active component cryptotanshinone protects primary cultured rat hepatocytes from acute ethanol-induced cytotoxicity and fatty infiltration.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Title: Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cryptotanshinone.
Journal: Journal of biomedicine & biotechnology 20090101
Title: Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC-DAD-ESI-MS(n).
Journal: Journal of pharmaceutical and biomedical analysis 20081104
Title: Vascular effects of different lipophilic components of 'Danshen', a traditional Chinese medicine, in the isolated porcine coronary artery.
Journal: Journal of natural products 20081101
Title: [Effects of cryptotanshinone in lowering androgens synthesis for the prenatally androgenized male rats].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20081101
Title: Dihydrotanshinone, a lipophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium channels.
Journal: Journal of ethnopharmacology 20080926
Title: T-DNA activation tagging as a tool to isolate Salvia miltiorrhiza transgenic lines for higher yields of tanshinones.
Journal: Planta medica 20080601
Title: Inhibition of prostaglandin and nitric oxide production in lipopolysaccharide-treated RAW 264.7 cells by tanshinones from the roots of Salvia miltiorrhiza bunge.
Journal: Archives of pharmacal research 20080601
Title: Simultaneous determination of tanshinone I, dihydrotanshinone I, tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study of a standardized fraction of Salvia miltiorrhiza, PF2401-SF.
Journal: Biomedical chromatography : BMC 20080501
Title: Pharmacokinetic characterization of hydroxylpropyl-beta-cyclodextrin-included complex of cryptotanshinone, an investigational cardiovascular drug purified from Danshen (Salvia miltiorrhiza).
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20080401
Title: Mechanisms of the dilator action of cryptotanshinone on rat coronary artery.
Journal: European journal of pharmacology 20080114
Title: Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101
Title: The correlation of Salvia miltiorrhiza extract-induced regulation of osteoclastogenesis with the amount of components tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone.
Journal: Immunopharmacology and immunotoxicology 20080101
Title: Effects of the coexisting diterpenoid tanshinones on the pharmacokinetics of cryptotanshinone and tanshinone IIA in rat.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201
Title: [Analysis on biomasses and contents of active components in roots of Salvia miltiorrhiza from different populations].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
Title: Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice.
Journal: European journal of pharmacology 20071128
Title: Simultaneous determination of danshensu, ferulic acid, cryptotanshinone and tanshinone IIA in rabbit plasma by HPLC and their pharmacokinetic application in danxiongfang.
Journal: Journal of pharmaceutical and biomedical analysis 20070903
Title: [Contrast studies on content of hydrophobic components between Salvia yunnanensis roots and Salvia miltiorrhiza roots].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070901
Title: Antidiabetes and antiobesity effect of cryptotanshinone via activation of AMP-activated protein kinase.
Journal: Molecular pharmacology 20070701
Title: Cryptotanshinone inhibits chemotactic migration in macrophages through negative regulation of the PI3K signaling pathway.
Journal: British journal of pharmacology 20070701
Title: Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.
Journal: Journal of natural products 20070701
Title: Cryptotanshinone inhibits macrophage migration by impeding F-actin polymerization and filopodia extension.
Journal: Life sciences 20070620
Title: Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.
Journal: Current drug metabolism 20070501
Title: Simultaneous determination of four tanshinones in Salvia miltiorrhiza by pressurized liquid extraction and capillary electrochromatography.
Journal: Journal of separation science 20070401
Title: [Pharmacokinetic interactions between the main components in the extracts of Salvia miltiorrhiza Bge. in rat].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301
Title: [Effects of methyl jasmonat on accumulation and release of tanshinones in suspension cultures of Salvia miltiorrhiza hairy root].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070201
Title: [Study on uniform-design for optimizing supercritical-CO2 fluid extraction technique of tanshinones in radix salviae].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201
Title: Cryptotanshinone inhibits cyclooxygenase-2 enzyme activity but not its expression.
Journal: European journal of pharmacology 20061107
Title: [Effect of micronization on the quality of Salvia miltiorrhiza Bge].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060801
Title: [Protective effect of tanshinones against liver injury in mice loaded with restraint stress].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060701
Title: A mechanistic study of the intestinal absorption of cryptotanshinone, the major active constituent of Salvia miltiorrhiza.
Journal: The Journal of pharmacology and experimental therapeutics 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Simultaneous quantification of cryptotanshinone and its active metabolite tanshinone IIA in plasma by liquid chromatography/tandem mass spectrometry (LC-MS/MS).
Journal: Journal of pharmaceutical and biomedical analysis 20060213
Title: High-performance liquid chromatographic determination of tanshinones in the roots of Salvia miltiorrhiza and related traditional chinese medicinal preparations.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20060101
Title: Determination of cryptotanshinone and its metabolite in rat plasma by liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051205
Title: Simultaneous determination of tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography-electrospray ionisation-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105
Title: A trihomoabietane diterpenoid from Plectranthus grandidentatus and an unusual addition of acetone to the ortho-quinone system of cryptotanshinone.
Journal: Journal of natural products 20050901
Title: Induction and potentiation of diterpenoid tanshinone accumulation in Salvia miltiorrhiza hairy roots by beta-aminobutyric acid.
Journal: Applied microbiology and biotechnology 20050801
Title: Inhibition of osteoclast differentiation by tanshinones from the root of Salvia miltiorrhiza bunge.
Journal: Archives of pharmacal research 20050801
Title: Nitrogen-containing compounds from Salvia miltiorrhiza.
Journal: Journal of natural products 20050701
Title: Cryptotanshinone but not tanshinone IIA inhibits angiogenesisin vitro.
Journal: Experimental & molecular medicine 20050430
Title: Simultaneous determination of cryptotanshinone, tanshinone I and tanshinone IIA in traditional Chinese medicinal preparations containing Radix salvia miltiorrhiza by HPLC.
Journal: Journal of pharmaceutical and biomedical analysis 20050309
Title: Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza.
Journal: Journal of medicinal chemistry 20041104
Title: Identification of major active constituents in the fingerprint of Salvia miltiorrhiza Bunge developed by high-speed counter-current chromatography.
Journal: Journal of chromatography. A 20040702
Title: Studies on the spectroscopic behavior of cryptotanshinone, tanshinone IIA, and tanshinone I.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040301
Title: Study on the inclusion complexes of cryptotanshinone with beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031001
Title: Isolation and quantitative analysis of cryptotanshinone, an active quinoid diterpene formed in callus of Salvia miltiorrhiza BUNGE.
Journal: Biological & pharmaceutical bulletin 20030601
Title: [Extraction of three tanshinones from the root of Salvia miltiorrhiza Bunge by supercritical carbon dioxide fluid and their analysis with high performance liquid chromatography].
Journal: Se pu = Chinese journal of chromatography 20020101
Title: Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.
Journal: Journal of natural products 20011101
Title: [Spectroscopic studies on the binding of effective component of Chinese herbs with human serum albumin].
Journal: Guang pu xue yu guang pu fen xi = Guang pu 20011001
Title: [Isolation and elucidation of chemical constituents of Shandanshaoyao Decoction(I)].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010601
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Title: Ge Y, et al. Cryptotanshinone acts synergistically with imatinib to induce apoptosis of human chronic myeloid leukemia cells. Leuk Lymphoma. 2014 Jun 25:1-9.
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