37339-90-5,MFCD01773536
Catalog No.:AA00I79Z

37339-90-5 | Lentinan

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Purity
Availability
Price(USD)
Quantity
  
1g
Polysaccharide>30.0%
in stock  
$66.00   $46.00
- +
5g
Polysaccharide>30.0%
in stock  
$156.00   $109.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00I79Z
Chemical Name:
Lentinan
CAS Number:
37339-90-5
Molecular Formula:
C42H72O36
Molecular Weight:
1152.9995
MDL Number:
MFCD01773536
SMILES:
OCC1OC(OC2C(O)C(O)OC(C2O)COC2OC(CO)C(C(C2O)O)O)C(C(C1O)OC1OC(CO)C(C(C1O)OC1OC(COC2OC(CO)C(C(C2O)O)O)C(C(C1O)OC1OC(CO)C(C(C1O)O)O)O)O)O
Properties
Computed Properties
 
Complexity:
1820  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
35  
Heavy Atom Count:
78  
Hydrogen Bond Acceptor Count:
36  
Hydrogen Bond Donor Count:
23  
Rotatable Bond Count:
19  
XLogP3:
-13.3  

Literature

Title: Surface properties of polyurethanes modified by bioactive polysaccharide-based polyelectrolyte multilayers.

Journal: Colloids and surfaces. B, Biointerfaces 20121201

Title: Antitumor activity of mushroom polysaccharides: a review.

Journal: Food & function 20121101

Title: The LiCl effect on the conformation of lentinan in DMSO.

Journal: Biopolymers 20121001

Title: The effect of lentinan combination therapy for unresectable advanced gastric cancer.

Journal: Anticancer research 20120601

Title: [A case study of advanced gastric cancer patient treated with S-1+paclitaxel/lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20120501

Title: Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma.

Journal: Molecular medicine reports 20120301

Title: β-Glucan from Lentinus edodes inhibits nitric oxide and tumor necrosis factor-α production and phosphorylation of mitogen-activated protein kinases in lipopolysaccharide-stimulated murine RAW 264.7 macrophages.

Journal: The Journal of biological chemistry 20120106

Title: Synthesis and macrophage activation of lentinan-mimic branched amino polysaccharides: curdlans having N-Acetyl-d-glucosamine branches.

Journal: Biomacromolecules 20110613

Title: [Combination chemotherapy of S-1/low-dose CDDP/lentinan for advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20110201

Title: Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.

Journal: International journal of oncology 20100901

Title: [A case of advanced gastric cancer responding to S-1/paclitaxel/lentinan as neoadjuvant chemoimmunotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100701

Title: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells.

Journal: International journal of oncology 20100601

Title: [A case of gastric cancer with para-aortic lymph node metastasis successfully treated with S-1/paclitaxel/lentinan combination therapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100601

Title: [A case of advanced gastric cancer with distant lymph node metastases in cervical, supraclavicular and superior mediastinum successfully treated with S-1/Cisplatin (CDDP)/Lentinan combination chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100401

Title: [Provision for adverse effect of S-1 containing chemotherapy in patients with advanced digestive cancer--combination with superfine dispersed lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20100301

Title: Renaturation of triple helical polysaccharide lentinan in water-diluted dimethylsulfoxide solution.

Journal: Carbohydrate research 20100211

Title: Lentinus edodes: a macrofungus with pharmacological activities.

Journal: Current medicinal chemistry 20100101

Title: Lentinan: hematopoietic, immunological, and efficacy studies in a syngeneic model of acute myeloid leukemia.

Journal: Nutrition and cancer 20100101

Title: Physicochemical properties and antitumor activities for sulfated derivatives of lentinan.

Journal: Carbohydrate research 20091102

Title: Beta-glucans in higher fungi and their health effects.

Journal: Nutrition reviews 20091101

Title: [Alleviation of seasonal allergic symptoms with superfine beta-1,3-glucan: a randomized study].

Journal: Nippon Ganka Gakkai zasshi 20091101

Title: [A case of the local advanced gastric cancer which became a resection possible in S-1/CDDP/lentinan neoadjuvant chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20091101

Title: Multiple conformation transitions of triple helical lentinan in DMSO/water by microcalorimetry.

Journal: The journal of physical chemistry. B 20090723

Title: [Lentinan-graft-polyethylenimine-a novel vector for gene delivery].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090101

Title: Lentinan with S-1 and paclitaxel for gastric cancer chemotherapy improve patient quality of life.

Journal: Hepato-gastroenterology 20090101

Title: [Clinical trial of non-specific immunotherapy using Lentinan in advanced or recurrent gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20081101

Title: Gel formation and low-temperature intramolecular conformation transition of a triple-helical polysaccharide lentinan in water.

Journal: Biopolymers 20081001

Title: The effect of Gankang Suppository on duck hepatitis B virus, serum biochemistry and liver histology in ducklings.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080801

Title: [Case of gastric cancer with recurrence of carcinomatous lymphangiosis of the lung 7.6 years after surgery and successfully treated with S-1/low-dose CDDP/Lentinan combination therapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20080601

Title: Recent studies on reaction pathways and applications of sugar orthoesters in synthesis of oligosaccharides.

Journal: Carbohydrate research 20070226

Title: [Establishment of a transgenic cell model for preliminary screening of chemopreventive agents].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20070101

Title: [S-1 combined with lentinan in patients with unresectable or recurrent gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060601

Title: [Protective effects of lentinan on the diaphragm mitochondria from experimental diabetic rats].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060501

Title: Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers.

Journal: Journal of experimental therapeutics & oncology 20060101

Title: [Anticancer immunotherapy with perorally effective lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050801

Title: Correlation between antitumor activity, molecular weight, and conformation of lentinan.

Journal: Carbohydrate research 20050613

Title: Dendritic cells might be one of key factors for eliciting antitumor effect by chemoimmunotherapy in vivo.

Journal: Cancer immunology, immunotherapy : CII 20050201

Title: [TS-1/CDDP/Lentinan combination chemotherapy for inoperable advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20041101

Title: [Two case reports of complete regression of liver metastases from colorectal cancer after locoregional immunochemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20041001

Title: [A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040201

Title: Collapse and association of denatured lentinan in water/dimethlysulfoxide solutions.

Journal: Biomacromolecules 20040101

Title: Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver.

Journal: BioFactors (Oxford, England) 20040101

Title: The beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3)-linked bond have similar stimulatory effects on the mouse spleen as Lentinan.

Journal: International immunopharmacology 20031201

Title: Synthesis of two heptasaccharide analogues of the lentinan repeating unit.

Journal: Carbohydrate research 20031121

Title: [TS-1 and lentinan combination immunochemotherapy for advanced or recurrent gastric cancer: a preliminary report].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20031001

Title: [Pilot study of TS-1 combined with lentinan in patients with unresectable or recurrent advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030901

Title: Synthesis of beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3) linked bond with antitumor activity.

Journal: Bioorganic & medicinal chemistry 20030515

Title: Effects of lentinan on broiler splenocyte proliferation, interleukin-2 production, and signal transduction.

Journal: Poultry science 20030501

Title: [A case of type 4 gastric cancer, diagnosed after operation for Krukenberg's tumor, treated by TS-1 plus low-dose cisplatinum].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030201

Title: [Postoperative adjuvant immunochemotherapy using Lentinan for advanced gastric carcinoma patients with metastasis in the regional lymph nodes and serosal invasion].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20021101

Title: Effects of intraperitoneal and intranasal application of Lentinan on cellular response in rats.

Journal: International immunopharmacology 20021101

Title: Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice.

Journal: Bioscience, biotechnology, and biochemistry 20020701

Title: Expression of multidrug resistance-associated protein1,P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection.

Journal: British journal of cancer 20020520

Title: The skewing to Th1 induced by lentinan is directed through the distinctive cytokine production by macrophages with elevated intracellular glutathione content.

Journal: International immunopharmacology 20020401

Title: Antiviral agents with activity against human retroviruses.

Journal: Journal of acquired immune deficiency syndromes 19890101

Title: Ina K, et al. The use of lentinan for treating gastric cancer. Anticancer Agents Med Chem. 2013 Jun;13(5):681-8.

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SDS
Tags:37339-90-5 Molecular Formula|37339-90-5 MDL|37339-90-5 SMILES|37339-90-5 Lentinan
Catalog No.: AA00I79Z
37339-90-5,MFCD01773536
37339-90-5 | Lentinan
Pack Size: 1g
Purity: Polysaccharide>30.0%
in stock
$66.00 $46.00
Pack Size: 5g
Purity: Polysaccharide>30.0%
in stock
$156.00 $109.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA00I79Z
Chemical Name: Lentinan
CAS Number: 37339-90-5
Molecular Formula: C42H72O36
Molecular Weight: 1152.9995
MDL Number: MFCD01773536
SMILES: OCC1OC(OC2C(O)C(O)OC(C2O)COC2OC(CO)C(C(C2O)O)O)C(C(C1O)OC1OC(CO)C(C(C1O)OC1OC(COC2OC(CO)C(C(C2O)O)O)C(C(C1O)OC1OC(CO)C(C(C1O)O)O)O)O)O
Properties
Complexity: 1820  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 35  
Heavy Atom Count: 78  
Hydrogen Bond Acceptor Count: 36  
Hydrogen Bond Donor Count: 23  
Rotatable Bond Count: 19  
XLogP3: -13.3  
Literature fold

Title: Surface properties of polyurethanes modified by bioactive polysaccharide-based polyelectrolyte multilayers.

Journal: Colloids and surfaces. B, Biointerfaces20121201

Title: Antitumor activity of mushroom polysaccharides: a review.

Journal: Food & function20121101

Title: The LiCl effect on the conformation of lentinan in DMSO.

Journal: Biopolymers20121001

Title: The effect of lentinan combination therapy for unresectable advanced gastric cancer.

Journal: Anticancer research20120601

Title: [A case study of advanced gastric cancer patient treated with S-1+paclitaxel/lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20120501

Title: Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma.

Journal: Molecular medicine reports20120301

Title: β-Glucan from Lentinus edodes inhibits nitric oxide and tumor necrosis factor-α production and phosphorylation of mitogen-activated protein kinases in lipopolysaccharide-stimulated murine RAW 264.7 macrophages.

Journal: The Journal of biological chemistry20120106

Title: Synthesis and macrophage activation of lentinan-mimic branched amino polysaccharides: curdlans having N-Acetyl-d-glucosamine branches.

Journal: Biomacromolecules20110613

Title: [Combination chemotherapy of S-1/low-dose CDDP/lentinan for advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20110201

Title: Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.

Journal: International journal of oncology20100901

Title: [A case of advanced gastric cancer responding to S-1/paclitaxel/lentinan as neoadjuvant chemoimmunotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100701

Title: Effects of potential calcium sensing receptor inducers on promoting chemosensitivity of human colon carcinoma cells.

Journal: International journal of oncology20100601

Title: [A case of gastric cancer with para-aortic lymph node metastasis successfully treated with S-1/paclitaxel/lentinan combination therapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100601

Title: [A case of advanced gastric cancer with distant lymph node metastases in cervical, supraclavicular and superior mediastinum successfully treated with S-1/Cisplatin (CDDP)/Lentinan combination chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100401

Title: [Provision for adverse effect of S-1 containing chemotherapy in patients with advanced digestive cancer--combination with superfine dispersed lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20100301

Title: Renaturation of triple helical polysaccharide lentinan in water-diluted dimethylsulfoxide solution.

Journal: Carbohydrate research20100211

Title: Lentinus edodes: a macrofungus with pharmacological activities.

Journal: Current medicinal chemistry20100101

Title: Lentinan: hematopoietic, immunological, and efficacy studies in a syngeneic model of acute myeloid leukemia.

Journal: Nutrition and cancer20100101

Title: Physicochemical properties and antitumor activities for sulfated derivatives of lentinan.

Journal: Carbohydrate research20091102

Title: Beta-glucans in higher fungi and their health effects.

Journal: Nutrition reviews20091101

Title: [Alleviation of seasonal allergic symptoms with superfine beta-1,3-glucan: a randomized study].

Journal: Nippon Ganka Gakkai zasshi20091101

Title: [A case of the local advanced gastric cancer which became a resection possible in S-1/CDDP/lentinan neoadjuvant chemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20091101

Title: Multiple conformation transitions of triple helical lentinan in DMSO/water by microcalorimetry.

Journal: The journal of physical chemistry. B20090723

Title: [Lentinan-graft-polyethylenimine-a novel vector for gene delivery].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences20090101

Title: Lentinan with S-1 and paclitaxel for gastric cancer chemotherapy improve patient quality of life.

Journal: Hepato-gastroenterology20090101

Title: [Clinical trial of non-specific immunotherapy using Lentinan in advanced or recurrent gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20081101

Title: Gel formation and low-temperature intramolecular conformation transition of a triple-helical polysaccharide lentinan in water.

Journal: Biopolymers20081001

Title: The effect of Gankang Suppository on duck hepatitis B virus, serum biochemistry and liver histology in ducklings.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban20080801

Title: [Case of gastric cancer with recurrence of carcinomatous lymphangiosis of the lung 7.6 years after surgery and successfully treated with S-1/low-dose CDDP/Lentinan combination therapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20080601

Title: Recent studies on reaction pathways and applications of sugar orthoesters in synthesis of oligosaccharides.

Journal: Carbohydrate research20070226

Title: [Establishment of a transgenic cell model for preliminary screening of chemopreventive agents].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology20070101

Title: [S-1 combined with lentinan in patients with unresectable or recurrent gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060601

Title: [Protective effects of lentinan on the diaphragm mitochondria from experimental diabetic rats].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20060501

Title: Cancer chronomics III. Chronomics for cancer, aging, melatonin and experimental therapeutics researchers.

Journal: Journal of experimental therapeutics & oncology20060101

Title: [Anticancer immunotherapy with perorally effective lentinan].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20050801

Title: Correlation between antitumor activity, molecular weight, and conformation of lentinan.

Journal: Carbohydrate research20050613

Title: Dendritic cells might be one of key factors for eliciting antitumor effect by chemoimmunotherapy in vivo.

Journal: Cancer immunology, immunotherapy : CII20050201

Title: [TS-1/CDDP/Lentinan combination chemotherapy for inoperable advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041101

Title: [Two case reports of complete regression of liver metastases from colorectal cancer after locoregional immunochemotherapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20041001

Title: [A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20040201

Title: Collapse and association of denatured lentinan in water/dimethlysulfoxide solutions.

Journal: Biomacromolecules20040101

Title: Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver.

Journal: BioFactors (Oxford, England)20040101

Title: The beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3)-linked bond have similar stimulatory effects on the mouse spleen as Lentinan.

Journal: International immunopharmacology20031201

Title: Synthesis of two heptasaccharide analogues of the lentinan repeating unit.

Journal: Carbohydrate research20031121

Title: [TS-1 and lentinan combination immunochemotherapy for advanced or recurrent gastric cancer: a preliminary report].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20031001

Title: [Pilot study of TS-1 combined with lentinan in patients with unresectable or recurrent advanced gastric cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030901

Title: Synthesis of beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3) linked bond with antitumor activity.

Journal: Bioorganic & medicinal chemistry20030515

Title: Effects of lentinan on broiler splenocyte proliferation, interleukin-2 production, and signal transduction.

Journal: Poultry science20030501

Title: [A case of type 4 gastric cancer, diagnosed after operation for Krukenberg's tumor, treated by TS-1 plus low-dose cisplatinum].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20030201

Title: [Postoperative adjuvant immunochemotherapy using Lentinan for advanced gastric carcinoma patients with metastasis in the regional lymph nodes and serosal invasion].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20021101

Title: Effects of intraperitoneal and intranasal application of Lentinan on cellular response in rats.

Journal: International immunopharmacology20021101

Title: Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice.

Journal: Bioscience, biotechnology, and biochemistry20020701

Title: Expression of multidrug resistance-associated protein1,P-glycoprotein, and thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection.

Journal: British journal of cancer20020520

Title: The skewing to Th1 induced by lentinan is directed through the distinctive cytokine production by macrophages with elevated intracellular glutathione content.

Journal: International immunopharmacology20020401

Title: Antiviral agents with activity against human retroviruses.

Journal: Journal of acquired immune deficiency syndromes19890101

Title: Ina K, et al. The use of lentinan for treating gastric cancer. Anticancer Agents Med Chem. 2013 Jun;13(5):681-8.

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