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Home Amines 524-36-7
524-36-7,MFCD00012808
Catalog No.:AA00I9AR

524-36-7 | Pyridoxamine DiHCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$8.00   $6.00
- +
5g
97%
in stock  
$27.00   $19.00
- +
25g
97%
in stock  
$67.00   $47.00
- +
100g
97%
in stock  
$231.00   $162.00
- +
500g
97%
in stock  
$809.00   $567.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I9AR
Chemical Name:
Pyridoxamine DiHCl
CAS Number:
524-36-7
Molecular Formula:
C8H14Cl2N2O2
Molecular Weight:
241.1150
MDL Number:
MFCD00012808
SMILES:
NCc1c(CO)cnc(c1O)C.Cl.Cl
Properties
Properties
 
BP:
460.1°C at 760 mmHg  
Form:
Solid  
MP:
224-226 °C (dec.)(lit.)  
Refractive Index:
1.6100 (estimate)  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
143  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
2  

Upstream Synthesis Route

[1]Patent:WO2006/66806,2006,A1,.Locationinpatent:Page/Pagecolumn16

[2]Patent:WO2013/167991,2013,A1,.Locationinpatent:Paragraph00103;00104

[3]Patent:US2015/141468,2015,A1,.Locationinpatent:Paragraph0110;0119;0120

[1]Patent:WO2005/77902,2005,A2,.Locationinpatent:Page/Pagecolumn40-42

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

[1]PharmaceuticalChemistryJournal,1980,vol.14,#6,p.407-409

[2]Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,#6,p.79-81

Downstream Synthesis Route

[1]JournalofOrganicChemistry,1957,vol.22,p.825

[1]PharmaceuticalChemistryJournal,1980,vol.14,p.407-409    Khimiko-FarmatsevticheskiiZhurnal,1980,vol.14,p.79-81

113-24-6    524-36-7   
C11H12N2O4(2-) 

[1]JournaloftheAmericanChemicalSociety,1986,vol.108,p.1969-1979

[1]Tetrahedron,1988,vol.44,p.7283-7292

[1]JournaloftheAmericanChemicalSociety,2003,vol.125,p.12110-12111

Literature

Title: Pyridorin in type 2 diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Pyridoxamine, advanced glycation inhibition, and diabetic nephropathy.

Journal: Journal of the American Society of Nephrology : JASN 20120101

Title: Stitt A, et al. The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes. Diabetes. 2002 Sep;51(9):2826-32.

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SDS
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