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529-59-9,MFCD00016883
Catalog No.:AA00I9DE

529-59-9 | Genistin

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5mg
98%
in stock  
$8.00   $6.00
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10mg
98%
in stock  
$11.00   $8.00
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250mg
98%
in stock  
$35.00   $25.00
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1g
98%
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$100.00   $70.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I9DE
Chemical Name:
Genistin
CAS Number:
529-59-9
Molecular Formula:
C21H20O10
Molecular Weight:
432.3775
MDL Number:
MFCD00016883
SMILES:
OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)occ(c3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
675  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
4  
XLogP3:
0.9  

Upstream Synthesis Route

[1]EuropeanJournalofOrganicChemistry,2008,#33,p.5622-5629

[1]EuropeanJournalofOrganicChemistry,2008,#33,p.5622-5629

[1]Phytochemistry(Elsevier),1986,vol.25,#11,p.2687-2688

[1]ChemicalandPharmaceuticalBulletin,1992,vol.40,#7,p.1978-1980

[1]AgriculturalandBiologicalChemistry,1980,vol.44,#2,p.469-470

Downstream Synthesis Route
67-56-1   
genistein7-O-(2"-p-coumaroyl-β-D-glucopyranoside) 
  3943-97-3    529-59-9 

[1]Phytochemistry,1986,vol.25,p.2687-2688

[1]ChemicalandPharmaceuticalBulletin,1992,vol.40,p.1978-1980

[1]AgriculturalandBiologicalChemistry,1980,vol.44,p.469-470

446-72-0    572-09-8    529-59-9   
5-Hydroxy-7-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-3-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl-chromen-4-one 

[1]JournaloftheChemicalSociety.PerkintransactionsI,1998,p.2481-2484

Literature

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Title: The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis.

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Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20120101

Title: In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein.

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Title: Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: New synthetic pyridine derivate as potential elicitor in production of isoflavonoids and flavonoids in Trifolium pratense L. suspension culture.

Journal: TheScientificWorldJournal 20120101

Title: Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats.

Journal: Journal of nutrition and metabolism 20120101

Title: Isoflavones-Enriched Soy Protein Prevents CCL(4)-Induced Hepatotoxicity in Rats.

Journal: ISRN pharmacology 20120101

Title: Influence of fructooligosaccharide on pharmacokinetics of isoflavones in postmenopausal women.

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Title: Characterization of a GH3 family β-glucosidase from Dictyoglomus turgidum and its application to the hydrolysis of isoflavone glycosides in spent coffee grounds.

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Title: Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39.

Journal: Journal of agricultural and food chemistry 20111109

Title: Microarray analysis revealed different gene expression patterns in HepG2 cells treated with low and high concentrations of the extracts of Anacardium occidentale shoots.

Journal: Genes & nutrition 20111101

Title: Permanent oviduct posteriorization after neonatal exposure to the phytoestrogen genistein.

Journal: Environmental health perspectives 20111101

Title: Depolarization induces NR2A tyrosine phosphorylation and neuronal apoptosis.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20111101

Title: Effects of flavonoids on prostaglandin E2 production and on COX-2 and mPGES-1 expressions in activated macrophages.

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Journal: Applied microbiology and biotechnology 20110801

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Title: Evaluation of effect of isoflavone on thyroid economy & autoimmunity in oophorectomised women: a randomised, double-blind, placebo-controlled trial.

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Title: Screening of bacterial cytochrome P450s responsible for regiospecific hydroxylation of (iso)flavonoids.

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Title: Inhibition of Kv4.3 by genistein via a tyrosine phosphorylation-independent mechanism.

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Journal: Journal of chromatography. A 20100423

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Journal: Journal of agricultural and food chemistry 20100414

Title: Continuous microwave-assisted isoflavone extraction system: design and performance evaluation.

Journal: Bioresource technology 20100401

Title: Combination of genistin and fructooligosaccharides prevents bone loss in ovarian hormone deficiency.

Journal: Journal of medicinal food 20100401

Title: Angiotensin I-converting enzyme inhibitory activity and bioconversion of isoflavones by probiotics in soymilk supplemented with prebiotics.

Journal: International journal of food sciences and nutrition 20100301

Title: Association of intrauterine and early-life exposures with diagnosis of uterine leiomyomata by 35 years of age in the Sister Study.

Journal: Environmental health perspectives 20100301

Title: Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.

Journal: Nutrients 20100301

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Journal: Nutrients 20100301

Title: Differential binding with ERalpha and ERbeta of the phytoestrogen-rich plant Pueraria mirifica.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100201

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Journal: Journal of ethnopharmacology 20100108

Title: Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications.

Journal: Applied microbiology and biotechnology 20100101

Title: Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Effect of genistin on bone formation.

Journal: Frontiers in bioscience (Elite edition) 20100101

Title: Comparison of Puerariae Radix and its hydrolysate on stimulation of hyaluronic acid production in NHEK cells.

Journal: The American journal of Chinese medicine 20100101

Title: Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids.

Journal: Cancer cell international 20100101

Title: Bioactivity of isoflavones: assessment through a theoretical model as a way to obtain a 'Theoretical Efficacy Related to Estradiol (TERE)'.

Journal: International journal of molecular sciences 20100101

Title: Differential effects of whole soy extract and soy isoflavones on apoptosis in prostate cancer cells.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100101

Title: Soy isoflavones versus placebo in the treatment of climacteric vasomotor symptoms: systematic review and meta-analysis.

Journal: Menopause (New York, N.Y.) 20100101

Title: Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints.

Journal: International journal of molecular sciences 20100101

Title: Formation of succinyl genistin and succinyl daidzin by Bacillus species.

Journal: Journal of food science 20100101

Title: Graptopetalum paraguayense E. Walther leaf extracts protect against brain injury in ischemic rats.

Journal: The American journal of Chinese medicine 20100101

Title: A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity.

Journal: Journal of osteoporosis 20100101

Title: Preventive effects of Flos Perariae (Gehua) water extract and its active ingredient puerarin in rodent alcoholism models.

Journal: Chinese medicine 20100101

Title: The significance of soy protein and soy bioactive compounds in the prophylaxis and treatment of osteoporosis.

Journal: Journal of osteoporosis 20100101

Title: Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease.

Journal: PloS one 20100101

Title: Anti-photoaging effects of soy isoflavone extract (aglycone and acetylglucoside form) from soybean cake.

Journal: International journal of molecular sciences 20100101

Title: Phytoconstituents as photoprotective novel cosmetic formulations.

Journal: Pharmacognosy reviews 20100101

Title: Current knowledge and future direction of research on soy isoflavones as a therapeutic agents.

Journal: Pharmacognosy reviews 20100101

Title: Oral exposure to genistin, the glycosylated form of genistein, during neonatal life adversely affects the female reproductive system.

Journal: Environmental health perspectives 20091201

Title: [Isoflavones from vines of Pueraria lobata].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: Isoflavonoids - an overview of their biological activities and potential health benefits.

Journal: Interdisciplinary toxicology 20091201

Title: Hydrolysis of soy isoflavone glycosides by recombinant beta-glucosidase from hyperthermophile Thermotoga maritima.

Journal: Journal of industrial microbiology & biotechnology 20091101

Title: Soy formula and isoflavones and the developing intestine.

Journal: Nutrition reviews 20091101

Title: Influence of ripeness and drying process on the polyphenols and tocopherols of Pistacia vera L.

Journal: Molecules (Basel, Switzerland) 20091030

Title: Marked individual variation in isoflavone metabolism after a soy challenge can modulate the skeletal effect of isoflavones in premenopausal women.

Journal: Journal of Korean medical science 20091001

Title: Chromatographic quantification of isoflavone content from soy derivates using HPLC technique.

Journal: Journal of chromatographic science 20091001

Title: Hypolipidemic effects of Monascus-fermented soybean extracts in rats fed a high-fat and -cholesterol diet.

Journal: Journal of agricultural and food chemistry 20090923

Title: Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers.

Journal: Prostate cancer and prostatic diseases 20090901

Title: Glycosylation of dietary flavonoids decreases the affinities for plasma protein.

Journal: Journal of agricultural and food chemistry 20090812

Title: Inhibition of MMP-3 activity and invasion of the MDA-MB-231 human invasive breast carcinoma cell line by bioflavonoids.

Journal: Acta pharmacologica Sinica 20090801

Title: [Constituents of Millettia nitida var. hirsutissima].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090801

Title: Effects of a methanolic fraction of soybean seeds on the transcriptional activity of peroxisome proliferator-activated receptors (PPAR).

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090601

Title: Inhibitory activity of isoflavones of Pueraria flowers on nitric oxide production from lipopolysaccharide-activated primary rat microglia.

Journal: Journal of Asian natural products research 20090601

Title: Effect of Soybean Hypocotyl Extract on Lipid Peroxidation in GK Rats.

Journal: Journal of clinical biochemistry and nutrition 20090501

Title: Effect of glycosidation of isoflavones on their bioavailability and pharmacokinetics in aged male rats.

Journal: Molecular nutrition & food research 20090501

Title: Influence of hydroxylation and glycosylation in ring A of soybean isoflavones on interaction with BSA.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090401

Title: Rapid analysis of Radix puerariae by near-infrared spectroscopy.

Journal: Journal of chromatography. A 20090313

Title: Stability of isoflavone isomers in steamed black soybeans and black soybean koji stored under different conditions.

Journal: Journal of agricultural and food chemistry 20090311

Title: Equol is more active than soy isoflavone itself to compete for binding to thromboxane A(2) receptor in human platelets.

Journal: Thrombosis research 20090301

Title: Characterization of newly isolated Lactobacillus delbrueckii-like strain MF-07 isolated from chicken and its role in isoflavone biotransformation.

Journal: FEMS microbiology letters 20090201

Title: The effect of tyrosine kinase inhibitor genistein on voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells.

Journal: Vascular pharmacology 20090101

Title: Effects of probiotic bacteria, isoflavones and simvastatin on lipid profile and atherosclerosis in cholesterol-fed rabbits: a randomized double-blind study.

Journal: Lipids in health and disease 20090101

Title: The phytoestrogen genistein affects zebrafish development through two different pathways.

Journal: PloS one 20090101

Title: Nanonized black soybean enhances immune response in senescence-accelerated mice.

Journal: International journal of nanomedicine 20090101

Title: Comparison of hormonal activity of isoflavone-containing supplements used to treat menopausal complaints.

Journal: Menopause (New York, N.Y.) 20090101

Title: Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.

Journal: PloS one 20090101

Title: Effects of isoflavone-supplemented soy yogurt on lipid parameters and atherosclerosis development in hypercholesterolemic rabbits: a randomized double-blind study.

Journal: Lipids in health and disease 20090101

Title: Isoflavonoid production in a hairy roots culture of Pueraria candollei.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: Developmental and Reproductive Effects of SE5-OH: An Equol-Rich Soy-Based Ingredient.

Journal: Journal of toxicology 20090101

Title: MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals.

Journal: Genetics and molecular biology 20090101

Title: Comparative metabolic profiling reveals secondary metabolites correlated with soybean salt tolerance.

Journal: Journal of agricultural and food chemistry 20081210

Title: Biomolecules and nutritional quality of soymilk fermented with probiotic yeast and bacteria.

Journal: Applied biochemistry and biotechnology 20081201

Title: Effects of dietary flavonoids on the transport of cimetidine via P-glycoprotein and cationic transporters in Caco-2 and LLC-PK1 cell models.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20081201

Title: Characterization of phenolic substances and antioxidant properties of food soybeans grown in the North Dakota-Minnesota region.

Journal: Journal of agricultural and food chemistry 20081008

Title: Phytoestrogens and breast cancer: a complex story.

Journal: Inflammopharmacology 20081001

Title: Effects of riboflavin photosensitization on the changes of isoflavones in soymilk.

Journal: Journal of food science 20080901

Title: Isoflavonoid composition of a callus culture of the relict tree Maackia amurensis Rupr. et Maxim.

Journal: Journal of agricultural and food chemistry 20080827

Title: Plasma profiling of intact isoflavone metabolites by high-performance liquid chromatography and mass spectrometric identification of flavone glycosides daidzin and genistin in human plasma after administration of kinako.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein.

Journal: British journal of pharmacology 20080801

Title: The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile.

Journal: Clinical nutrition (Edinburgh, Scotland) 20080801

Title: Accumulation of isoflavone genistin in transgenic tomato plants overexpressing a soybean isoflavone synthase gene.

Journal: Journal of agricultural and food chemistry 20080723

Title: Anti-platelet effects of flavonoids and flavonoid-glycosides from Sophora japonica.

Journal: Archives of pharmacal research 20080701

Title: Ultrahigh-pressure liquid chromatography of isoflavones and phenolic acids on different stationary phases.

Journal: Journal of chromatography. A 20080627

Title: Biotic elicitation of the Trifolium pratense L. suspension culture.

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20080601

Title: The role of early life genistein exposures in modifying breast cancer risk.

Journal: British journal of cancer 20080506

Title: Puma is a novel target of soy isoflavone genistein but is dispensable for genistein-induced cell fate determination.

Journal: Molecular nutrition & food research 20080401

Title: Meeting report: batch-to-batch variability in estrogenic activity in commercial animal diets--importance and approaches for laboratory animal research.

Journal: Environmental health perspectives 20080301

Title: Hydrolysis of isoflavone glucosides in soymilk fermented with single or mixed cultures of Lactobacillus paraplantarum KM, Weissella sp. 33, and Enterococcus faecium 35 isolated from humans.

Journal: Journal of microbiology and biotechnology 20080301

Title: Metabolic activation promotes estrogenic activity of the phytoestrogen-rich plant.

Journal: Maturitas 20080220

Title: Characterization of a thermostable extracellular beta-glucosidase with activities of exoglucanase and transglycosylation from Paecilomyces thermophila.

Journal: Journal of agricultural and food chemistry 20080123

Title: Cloning, expression, and characterization of two beta-glucosidases from isoflavone glycoside-hydrolyzing Bacillus subtilis natto.

Journal: Journal of agricultural and food chemistry 20080109

Title: Two new isoflavone triglycosides from the small branches of Sophora japonica.

Journal: Journal of Asian natural products research 20080101

Title: Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary.

Journal: Nutrition journal 20080101

Title: Two new isoflavone glycosides from Pueraria lobata.

Journal: Journal of Asian natural products research 20080101

Title: Sensitization of ovarian cancer cells to cisplatin by genistein: the role of NF-kappaB.

Journal: Journal of ovarian research 20080101

Title: Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.

Journal: Reproductive biology and endocrinology : RB&E 20080101

Title: Effects of soybean isoflavone extract on the plasma lipid profiles and antioxidant enzyme activity in streptozotocin-induced diabetic rats.

Journal: Nutrition research and practice 20080101

Title: Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts.

Journal: Analytical and bioanalytical chemistry 20071201

Title: Enhanced bioavailability of soy isoflavones by complexation with beta-cyclodextrin in rats.

Journal: Bioscience, biotechnology, and biochemistry 20071201

Title: Comparison of isoflavone concentrations in soybean (Glycine max (L.) Merrill) sprouts grown under two different light conditions.

Journal: Journal of agricultural and food chemistry 20071114

Title: Major isoflavonoid contents of the 1-year-cultivated phytoestrogen-rich herb, Pueraria mirifica.

Journal: Bioscience, biotechnology, and biochemistry 20071001

Title: A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice.

Journal: Environmental health perspectives 20071001

Title: Solvent effects on extraction and HPLC analysis of soybean isoflavones and variations of isoflavone compositions as affected by crop season.

Journal: Journal of agricultural and food chemistry 20070919

Title: In spermatozoa, Stat1 is activated during capacitation and the acrosomal reaction.

Journal: Reproduction (Cambridge, England) 20070901

Title: Phytoestrogens levels determination in the cord blood from Malaysia rural and urban populations.

Journal: Toxicology and applied pharmacology 20070701

Title: Bioavailability of soy isoflavones in rats Part I: application of accurate methodology for studying the effects of gender and source of isoflavones.

Journal: Molecular nutrition & food research 20070701

Title: Disruption of the developing female reproductive system by phytoestrogens: genistein as an example.

Journal: Molecular nutrition & food research 20070701

Title: Imaging poliovirus entry in live cells.

Journal: PLoS biology 20070701

Title: Comparison of oral bioavailability of genistein and genistin in rats.

Journal: International journal of pharmaceutics 20070607

Title: Biotransformation of common bean (Phaseolus vulgaris L.) flavonoid glycosides by bifidobacterium species from human intestinal origin.

Journal: Journal of agricultural and food chemistry 20070516

Title: Isolation of six isoflavones from Semen sojae praeparatum by preparative HPLC.

Journal: Fitoterapia 20070401

Title: Structure-activity relationships of flavonoids for vascular relaxation in porcine coronary artery.

Journal: Phytochemistry 20070401

Title: Pro-apoptotic effect and cytotoxicity of genistein and genistin in human ovarian cancer SK-OV-3 cells.

Journal: Life sciences 20070320

Title: Conversion of isoflavone glucosides to aglycones in soymilk by fermentation with lactic acid bacteria.

Journal: Journal of food science 20070301

Title: Major isoflavonoid contents of the phytoestrogen rich-herb Pueraria mirifica in comparison with Pueraria lobata.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Disruption of the female reproductive system by the phytoestrogen genistein.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20070101

Title: AVPV neurons containing estrogen receptor-beta in adult male rats are influenced by soy isoflavones.

Journal: BMC neuroscience 20070101

Title: [Genista tinctoria in vitro].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20070101

Title: Seasonal variations in the isoflavonoids of radix Puerariae.

Journal: Phytochemical analysis : PCA 20070101

Title: Review of the factors affecting bioavailability of soy isoflavones in humans.

Journal: Nutrition and cancer 20070101

Title: Anti-obesity activities of fermented soygerm isoflavones by Bifidobacterium breve.

Journal: BioFactors (Oxford, England) 20070101

Title: Effects of isoflavones and soybeans fermented with Bacillus subtilis on lipopolysaccharide-induced production of tumor necrosis factor-alpha and fibrinolysis in vivo.

Journal: Immunopharmacology and immunotoxicology 20070101

Title: Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages.

Journal: Mediators of inflammation 20070101

Title: Abstracts of papers presented at the 2007 pittsburgh conference.

Journal: Journal of automated methods & management in chemistry 20070101

Title: Phenolic compounds and bioactivity of leaves of Mayodendron igneum Kurz.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20070101

Title: Regulation of isoflavone production in hydroponically grown Pueraria montana (kudzu) by cork pieces, XAD-4, and methyl jasmonate.

Journal: Plant cell reports 20061201

Title: Isoflavonoids production in callus culture of Pueraria tuberosa, the Indian kudzu.

Journal: Indian journal of experimental biology 20061201

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Hydrolysis of black soybean isoflavone glycosides by Bacillus subtilis natto.

Journal: Applied microbiology and biotechnology 20061101

Title: Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration.

Journal: The Journal of steroid biochemistry and molecular biology 20061101

Title: Identification of genistein-inducible and type III-secreted proteins of Bradyrhizobium japonicum.

Journal: Journal of biotechnology 20061020

Title: Bioavailability of genistein and its glycoside genistin as measured in the portal vein of freely moving unanesthetized rats.

Journal: Journal of agricultural and food chemistry 20061018

Title: Heat and pH effects on the conjugated forms of genistin and daidzin isoflavones.

Journal: Journal of agricultural and food chemistry 20061004

Title: Constituents of the roots of Pueraria lobata inhibit formation of advanced glycation end products (AGEs).

Journal: Archives of pharmacal research 20061001

Title: Production of equol from daidzein by gram-positive rod-shaped bacterium isolated from rat intestine.

Journal: Journal of bioscience and bioengineering 20060901

Title: Method development and validation for isoflavones in soy germ pharmaceutical capsules using micellar electrokinetic chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20060828

Title: Interactions of genistein and related isoflavones with lipid micelles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060815

Title: Influence of the application of three different elicitors on soybean plants on the concentrations of several isoflavones in soybean seeds.

Journal: Journal of agricultural and food chemistry 20060726

Title: Tyrosine kinase inhibitors and ATP modulate the conversion of smooth muscle L-type Ca2+ channels toward a second open state.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701

Title: [Preparation of soybean isoflavone glucosides by reversed-phase high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20060701

Title: Tyrosine kinase and phosphatase regulation of slow delayed-rectifier K+ current in guinea-pig ventricular myocytes.

Journal: The Journal of physiology 20060601

Title: Assessing risks and benefits of genistein and soy.

Journal: Environmental health perspectives 20060601

Title: The science of soy: what do we really know?

Journal: Environmental health perspectives 20060601

Title: Water-soluble genistin glycoside isoflavones up-regulate antioxidant metallothionein expression and scavenge free radicals.

Journal: Journal of agricultural and food chemistry 20060531

Title: Distribution profiles of isoflavone isomers in black bean kojis prepared with various filamentous fungi.

Journal: Journal of agricultural and food chemistry 20060222

Title: Genistin inhibits UV light-induced plasmid DNA damage and cell growth in human melanoma cells.

Journal: The Journal of nutritional biochemistry 20060201

Title: Effect of protein tyrosine kinase inhibitors on the current through the Ca(V)3.1 channel.

Journal: Archives of biochemistry and biophysics 20060201

Title: Soy phytochemicals prevent orthotopic growth and metastasis of bladder cancer in mice by alterations of cancer cell proliferation and apoptosis and tumor angiogenesis.

Journal: Cancer research 20060201

Title: Oral administration of soy-derived genistin suppresses lipopolysaccharide-induced acute liver inflammation but does not induce thymic atrophy in the rat.

Journal: Life sciences 20060118

Title: Isoflavone levels in five soybean (Glycine max) genotypes are altered by phytochrome-mediated light treatments.

Journal: Journal of agricultural and food chemistry 20060111

Title: Crohn's disease leading to bowel cancer may be avoided by consumption of soya isoflavones: adjunct-chemotherapy with oxaliplatin.

Journal: Medical hypotheses 20060101

Title: Plant polyphenols and multidrug resistance: effects of dietary flavonoids on drug transporters in Caco-2 and MDCKII-MDR1 cell transport models.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060101

Title: Isoflavonoids are present in Arabidopsis thaliana despite the absence of any homologue to known isoflavonoid synthases.

Journal: Plant physiology and biochemistry : PPB 20060101

Title: 'Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells'.

Journal: Cancer cell international 20060101

Title: An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection.

Journal: Journal of AOAC International 20060101

Title: Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized BALB/c mice.

Journal: Journal of agricultural and food chemistry 20051102

Title: Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051101

Title: Selective inhibitors of terminal deoxyribonucleotidyltransferase (TdT): baicalin and genistin.

Journal: Biochimica et biophysica acta 20051010

Title: [Simultaneous determination of the four effective components in Huaijiao pill by HPLC].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051001

Title: Dexamethasone and cardiac potassium currents in the diabetic rat.

Journal: British journal of pharmacology 20050901

Title: Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts.

Journal: Acta pharmacologica Sinica 20050901

Title: Determination of isoflavones in soy bits by fast column high-performance liquid chromatography coupled with UV-visible diode-array detection.

Journal: Journal of chromatography. A 20050819

Title: Glycosylation of genistin into soluble inclusion complex form of cyclic glucans by enzymatic modification.

Journal: Journal of agricultural and food chemistry 20050810

Title: Flavonoid glycosides inhibit oral cancer cell proliferation--role of cellular uptake and hydrolysis to the aglycones.

Journal: The Journal of pharmacy and pharmacology 20050801

Title: Supercritical fluid extraction of isoflavones from biological samples with ultra-fast high-performance liquid chromatography/mass spectrometry.

Journal: Journal of separation science 20050801

Title: Evaluation of isoflavone aglycon and glycoside distribution in soy plants and soybeans by fast column high-performance liquid chromatography coupled with a diode-array detector.

Journal: Journal of agricultural and food chemistry 20050727

Title: Antipyretic, analgesic and muscle relaxant activities of pueraria isoflavonoids and their metabolites from Pueraria lobata Ohwi-a traditional Chinese drug.

Journal: Biological & pharmaceutical bulletin 20050701

Title: Are chemical compounds important for soybean resistance to Anticarsia gemmatalis?

Journal: Journal of chemical ecology 20050701

Title: Antioxidant enzymes and isoflavonoids in chilled soybean (Glycine max (L.) Merr.) seedlings.

Journal: Journal of plant physiology 20050401

Title: Pharmacokinetics of a slow-release formulation of soybean isoflavones in healthy postmenopausal women.

Journal: Journal of agricultural and food chemistry 20050323

Title: Simultaneous determination of phytoestrogens in different medicinal parts of Sophora japonica L. by capillary electrophoresis with electrochemical detection.

Journal: Biomedical chromatography : BMC 20050301

Title: Flavonoids differentially modulate nitric oxide production pathways in lipopolysaccharide-activated RAW264.7 cells.

Journal: Archives of pharmacal research 20050301

Title: Effect of temperature, elevated carbon dioxide, and drought during seed development on the isoflavone content of dwarf soybean [Glycine max (L.) Merrill] grown in controlled environments.

Journal: Journal of agricultural and food chemistry 20050223

Title: Assessment of estrogenic activity of flavonoids from Mediterranean plants using an in vitro short-term test.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20050101

Title: Pharmacokinetics of isoflavones, daidzein and genistein, after ingestion of soy beverage compared with soy extract capsules in postmenopausal Thai women.

Journal: BMC clinical pharmacology 20050101

Title: Two-stage system for micropropagation of several Genista plants producing large amounts of phytoestrogens.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Title: Influences of dietary soy isoflavones on metabolism but not nociception and stress hormone responses in ovariectomized female rats.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways.

Journal: International journal of oncology 20041101

Title: The protein tyrosine kinase inhibitor, genistein, decreases excitability of nociceptive neurons.

Journal: Pain 20041101

Title: Cumulative dietary energy intake determines the onset of puberty in female rats.

Journal: Environmental health perspectives 20041101

Title: Phloridzin improves absorption of genistin in isolated rat small intestine.

Journal: Clinical nutrition (Edinburgh, Scotland) 20041001

Title: Soy processing influences growth of estrogen-dependent breast cancer tumors.

Journal: Carcinogenesis 20040901

Title: Flavonoids of an extract of Pterospartum tridentatum showing endothelial protection against oxidative injury.

Journal: Journal of ethnopharmacology 20040801

Title: [Azoic color reaction of flavonoids and their analytical application].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20040801

Title: Enhancement of tofu isoflavone recovery by pretreatment of soy milk with koji enzyme extract.

Journal: Journal of agricultural and food chemistry 20040728

Title: Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types.

Journal: The Journal of steroid biochemistry and molecular biology 20040701

Title: Intestinal uptake of genistein and its glycoside in the rat using various isolated perfused gut segments.

Journal: Environmental toxicology and pharmacology 20040601

Title: Effect of water-to-bean ratio on the contents and compositions of isoflavones in tofu.

Journal: Journal of agricultural and food chemistry 20040421

Title: Effects of dose and glycosylation on the transfer of genistein into the eggs of the Japanese quail (Coturnix japonica).

Journal: Journal of agricultural and food chemistry 20040421

Title: Purification and characterization of an isoflavone-conjugates-hydrolyzing beta-glucosidase from endophytic bacterium.

Journal: Journal of agricultural and food chemistry 20040407

Title: Use of reporter cell lines for detection of endocrine-disrupter activity.

Journal: Analytical and bioanalytical chemistry 20040201

Title: Cytotoxic effects of some animal and vegetable extracts and some chemicals on liver and colon carcinoma and myosarcoma.

Journal: Saudi medical journal 20040201

Title: Cytostatic and cytotoxic activity of synthetic genistein glycosides against human cancer cell lines.

Journal: Cancer letters 20040108

Title: Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection.

Journal: Bioscience, biotechnology, and biochemistry 20040101

Title: Soybean isoflavones inhibit estrogen-stimulated gene expression in mouse uteri.

Journal: European journal of gynaecological oncology 20040101

Title: Kudzu root extract suppresses voluntary alcohol intake and alcohol withdrawal symptoms in P rats receiving free access to water and alcohol.

Journal: Journal of medicinal food 20040101

Title: Isoflavonoids in the Rutaceae family: 1. Fortunella obovata, Murraya paniculata and four Citrus species.

Journal: Phytochemical analysis : PCA 20040101

Title: Novel physiological function of fructooligosaccharides.

Journal: BioFactors (Oxford, England) 20040101

Title: Antitumor-promoting constituents from Chaenomeles sinensis KOEHNE and their activities in JB6 mouse epidermal cells.

Journal: Chemical & pharmaceutical bulletin 20031101

Title: [Study of the methods of determining the isoflavones in herbs of Trifolium pratense extractive].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20031101

Title: High isoflavone content and estrogenic activity of 25 year-old Glycine max tissue cultures.

Journal: Phytochemistry 20031001

Title: Ultrasound-assisted extraction of soy isoflavones.

Journal: Journal of chromatography. A 20030919

Title: Metabolism of the soybean isoflavone glycoside genistin in vitro by human gut bacteria and the effect of prebiotics.

Journal: The British journal of nutrition 20030901

Title: Block by phytoestrogens of recombinant human neuronal nicotinic receptors.

Journal: Journal of pharmacological sciences 20030901

Title: Mass spectrometric methods for the analysis of chlorinated and nitrated isoflavonoids: a novel class of biological metabolites.

Journal: Journal of mass spectrometry : JMS 20030701

Title: Flavone C-glycosides from Lupinus hartwegii.

Journal: Phytochemistry 20030601

Title: Upregulation of isoflavonoids and soluble proteins in edible legumes by light and fungal elicitor treatments.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20030601

Title: The effect of oestrogen and dietary phyto-oestrogens on transepithelial calcium transport in human intestinal-like Caco-2 cells.

Journal: The British journal of nutrition 20030601

Title: Flavonoid increase in soybean as a response to Nezara viridula injury and its effect on insect-feeding preference.

Journal: Journal of chemical ecology 20030501

Title: Evaluation of the estrogenic effects of legume extracts containing phytoestrogens.

Journal: Journal of agricultural and food chemistry 20030409

Title: Stability of isoflavones in soy milk stored at elevated and ambient temperatures.

Journal: Journal of agricultural and food chemistry 20030409

Title: Pharmacological activities of stromata of Cordyceps scarabaecola.

Journal: Phytotherapy research : PTR 20030301

Title: Determination of daidzein and genistein in soybean foods by automated on-line in-tube solid-phase microextraction coupled to high-performance liquid chromatography.

Journal: Journal of chromatography. A 20030207

Title: Noradrenaline- and melatonin-mediated regulation of pigment aggregation in fish melanophores.

Journal: Pigment cell research 20030201

Title: Evaluation of a soybean product fujiflavone P40 as an antiosteoporotic agent in rats.

Journal: Phytotherapy research : PTR 20030201

Title: Genistein inhibits Ca2+ influx and glutamate release from hippocampal synaptosomes: putative non-specific effects.

Journal: Neurochemistry international 20030101

Title: Isoflavone, glyphosate, and aminomethylphosphonic acid levels in seeds of glyphosate-treated, glyphosate-resistant soybean.

Journal: Journal of agricultural and food chemistry 20030101

Title: Determination of isoflavones in ready-to-feed soy-based infant formula.

Journal: Journal of AOAC International 20030101

Title: Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds.

Journal: Mutation research 20030101

Title: Stabilities of daidzin, glycitin, genistin, and generation of derivatives during heating.

Journal: Journal of agricultural and food chemistry 20021204

Title: Estrogenicity of isoflavones on human endometrial stromal and glandular cells.

Journal: The Journal of clinical endocrinology and metabolism 20021201

Title: Tissue factor inhibitory flavonoids from the fruits of Chaenomeles sinensis.

Journal: Archives of pharmacal research 20021201

Title: In vitro antioxidant activity of some selected Prunus species in Korea.

Journal: Archives of pharmacal research 20021201

Title: [Comparison of soyasaponin and isoflavone contents between genetically modified (GM) and non-GM soybeans].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021201

Title: Inhibition of orthotopic growth and metastasis of androgen-sensitive human prostate tumors in mice by bioactive soybean components.

Journal: The Prostate 20021001

Title: The effects of fish oil and isoflavones on delayed onset muscle soreness.

Journal: Medicine and science in sports and exercise 20021001

Title: ESR and cell culture studies on free radical-scavenging and antioxidant activities of isoflavonoids.

Journal: Toxicology 20020930

Title: Difference in flavonoid and isoflavone profile between soybean and soy leaf.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20020801

Title: Neuroprotective and neurotrophic efficacy of phytoestrogens in cultured hippocampal neurons.

Journal: Experimental biology and medicine (Maywood, N.J.) 20020701

Title: Phytoestrogen-low diet for endocrine disruptor studies.

Journal: Journal of agricultural and food chemistry 20020619

Title: Vascular effects of a soy leaves (Glycine max) extract and kaempferol glycosides in isolated rat carotid arteries.

Journal: Planta medica 20020601

Title: Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020401

Title: Isoflavone aglycon and glucoconjugate content of high- and low-soy U.K. foods used in nutritional studies.

Journal: Journal of agricultural and food chemistry 20020313

Title: Anaerobic C-ring cleavage of genistein and daidzein by Eubacterium ramulus.

Journal: FEMS microbiology letters 20020305

Title: Hypolipidemic action of the soybean isoflavones genistein and genistin in glomerulonephritic rats.

Journal: Lipids 20020301

Title: Efficacy and safety of a phytoestrogen preparation derived from Glycine max (L.) Merr in climacteric symptomatology: a multicentric, open, prospective and non-randomized trial.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020301

Title: Effects of naturally occurring isoflavones on prostaglandin E2 production.

Journal: Planta medica 20020201

Title: Chemosensitivity of human prostate cancer cells PC3 and LNCaP to genistein isoflavone and beta-lapachone.

Journal: Biology of the cell 20020201

Title: Comparative metabolism of genistin by human and rat gut microflora: detection and identification of the end-products of metabolism.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20020101

Title: Interaction of phytoestrogens with estrogen receptors alpha and beta (II).

Journal: Biological & pharmaceutical bulletin 20020101

Title: Inhibitory effect of isoflavones on peroxynitrite-mediated low-density lipoprotein oxidation.

Journal: Bioscience, biotechnology, and biochemistry 20020101

Title: [Isoflavones and calcified tissues].

Journal: Uspekhi fiziologicheskikh nauk 20020101

Title: Effects of a standardized soy extract on hot flushes: a multicenter, double-blind, randomized, placebo-controlled study.

Journal: Menopause (New York, N.Y.) 20020101

Title: Composition, red blood cell uptake, and serum protein binding of phytoestrogens extracted from commercial kudzu-root and soy preparations.

Journal: Journal of medicinal food 20020101

Title: Effect of spaceflight on isoflavonoid accumulation in etiolated soybean seedlings.

Journal: Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology 20011201

Title: Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia.

Journal: The Journal of biological chemistry 20011019

Title: Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein.

Journal: Carcinogenesis 20011001

Title: Separation and purification of isoflavones from a crude soybean extract by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20010914

Title: Isolating antigenotoxic components and cancer cell growth suppressors from agricultural by-products.

Journal: Mutation research 20010901

Title: Isoflavone transformation during soybean koji preparation and subsequent miso fermentation supplemented with ethanol and NaCl.

Journal: Journal of agricultural and food chemistry 20010801

Title: Four new isoflavone triglycosides from Sophora japonica.

Journal: Journal of natural products 20010801

Title: Genistein, a soybean isoflavone, inhibits inward rectifier K(+) channels in rat osteoclasts.

Journal: The Japanese journal of physiology 20010801

Title: Preparative separation of isoflavone components in soybeans using high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20010720

Title: Changes in the profile of genistein, daidzein, and their conjugates during thermal processing of tofu.

Journal: Journal of agricultural and food chemistry 20010601

Title: The effect of dietary soy genistein on pig growth and viral replication during a viral challenge.

Journal: Journal of animal science 20010501

Title: Interaction of phytoestrogens with estrogen receptors alpha and beta.

Journal: Biological & pharmaceutical bulletin 20010401

Title: Comparative study on reduction of bone loss and lipid metabolism abnormality in ovariectomized rats by soy isoflavones, daidzin, genistin, and glycitin.

Journal: Biological & pharmaceutical bulletin 20010401

Title: Effect of genistein analogs on oxygen radical production in leukocytes stimulated by unopsonized zymosan.

Journal: Planta medica 20010401

Title: [Daily intake of isoflavones based on the market basket method].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20010401

Title: Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Journal: Chemical research in toxicology 20010301

Title: [Bioavailability of soy isoflavones in supplements for menopausal women].

Journal: Presse medicale (Paris, France : 1983) 20010120

Title: Suppressive effects of dietary genistin and daidzin on rat prostate carcinogenesis.

Journal: Japanese journal of cancer research : Gann 20000801

Title: Choi YR, et al. Genistin: A Novel Potent Anti-Adipogenic and Anti-Lipogenic Agent. Molecules. 2020;25(9):2042. Published 2020 Apr 27.

Title: Liang Y, et al. A Comprehensive Screening and Identification of Genistin Metabolites in Rats Based on Multiple Metabolite Templates Combined with UHPLC-HRMS Analysis. Molecules. 2018;23(8):1862. Published 2018 Jul 26.

Title: Hwang ST, et al. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [published online ahead of print, 2020 Oct 16 Life Sci. 2020;263:118594.

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Tags:529-59-9 Molecular Formula|529-59-9 MDL|529-59-9 SMILES|529-59-9 Genistin