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532-03-6,MFCD00057662
Catalog No.:AA00I9F1

532-03-6 | Methocarbamol

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25mg
98%
in stock  
$7.00   $5.00
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100mg
98%
in stock  
$9.00   $7.00
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5g
98%
in stock  
$24.00   $17.00
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10g
98%
in stock  
$45.00   $32.00
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25g
98%
in stock  
$64.00   $45.00
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100g
98%
in stock  
$123.00   $86.00
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500g
98%
in stock  
$581.00   $407.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I9F1
Chemical Name:
Methocarbamol
CAS Number:
532-03-6
Molecular Formula:
C11H15NO5
Molecular Weight:
241.2405
MDL Number:
MFCD00057662
SMILES:
COc1ccccc1OCC(COC(=O)N)O
Properties
Computed Properties
 
Complexity:
236  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.6  

Upstream Synthesis Route

[1]MonatsheftefuerChemie,1963,vol.94,p.339-358

[2]MonatsheftefuerChemie,1963,vol.94,p.339-358

[1]MonatsheftefuerChemie,1963,vol.94,p.339-358

[2]MonatsheftefuerChemie,1963,vol.94,p.339-358

[1]MonatsheftefuerChemie,1963,vol.94,p.339-358

[1]MonatsheftefuerChemie,1963,vol.94,p.339-358

[1]MonatsheftefuerChemie,1963,vol.94,p.339-358

[2]MonatsheftefuerChemie,1963,vol.94,p.339-358

Downstream Synthesis Route
641-70-3    532-03-6   
Methocarbamol-mono-3-nitro-phthalat 

[1]JournalofPharmaceuticalSciences,1965,vol.54,p.1605-1609

532-03-6    528-76-7   
C17H17N3O9S 

[1]JournalofPharmaceuticalSciences,1965,vol.54,p.1605-1609

532-03-6    86-84-0   
Methocarbamol-(1-naphthylcarbamat) 

[1]JournalofPharmaceuticalSciences,1965,vol.54,p.1605-1609

[1]JournalofPharmaceuticalSciences,1994,vol.83,p.499-501

[1]MonatsheftefurChemie,1963,vol.94,p.339-358

Literature

Title: Simultaneous determination of methocarbamol and ibuprofen or diclofenac potassium using mean centering of the ratio spectra method.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20120601

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Rationally designed molecularly imprinted polymers for selective extraction of methocarbamol from human plasma.

Journal: Talanta 20110915

Title: Simultaneous spectrophotometric determination of diclofenac potassium and methocarbamol in binary mixture using chemometric techniques and artificial neural networks.

Journal: Drug testing and analysis 20110401

Title: Spectrofluorometric determination of methocarbamol in pharmaceutical preparations and human plasma.

Journal: Journal of fluorescence 20110301

Title: Strychnine poisoning: gone but not forgotten.

Journal: Emergency medicine journal : EMJ 20110101

Title: A case report of unusual vasculitic reaction after Methocarbamol injection.

Journal: Acta medica Iranica 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Electrochemical determination of methocarbamol on a montmorillonite-Ca modified carbon paste electrode in formulation and human blood.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20101001

Title: Simultaneous determination of diclofenac potassium and methocarbamol in ternary mixture with guaifenesin by reversed phase liquid chromatography.

Journal: Talanta 20100915

Title: [IGOST guideline for pharmacotherapy of low back pain].

Journal: MMW Fortschritte der Medizin 20100812

Title: Determination of methocarbamol concentration in human plasma by high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315

Title: Acetaminophen toxicity with concomitant use of carbamazepine.

Journal: Epileptic disorders : international epilepsy journal with videotape 20091201

Title: 50 Years Ago in CORR: A clinical study of 46 males with low-back disorders treated with Methocarbamol. Andres Grisolia MD and J.E.M. Thomson CORR 1959;13:299-304.

Journal: Clinical orthopaedics and related research 20091001

Title: Bioequivalence study with two different oral formulations of methocarbamol in healthy subjects. A mono-centre, comparative, randomized, open-label, single-dose, 2-way crossover study.

Journal: Arzneimittel-Forschung 20090101

Title: A stability-indicating high-performance liquid chromatographic method for the determination of methocarbamol in veterinary preparations.

Journal: Journal of AOAC International 20090101

Title: Efficacy and safety of sodium hyaluronate in the treatment of Wilkes stage II disease.

Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20081101

Title: How to try this: detecting delirium.

Journal: The American journal of nursing 20071201

Title: Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogue.

Journal: Journal of medicinal chemistry 20061130

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: A randomized clinical trial comparing chiropractic adjustments to muscle relaxants for subacute low back pain.

Journal: Journal of manipulative and physiological therapeutics 20040101

Title: Seizure-like behavior in cats.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20020101

Title: Simultaneous determination of paracetamol and methocarbamol in tablets by ratio spectra derivative spectrophotometry and LC.

Journal: Journal of pharmaceutical and biomedical analysis 20010101

Title: Focal seizure following enflurane.

Journal: Anaesthesia 19920101

Title: Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals.

Journal: European journal of clinical pharmacology 19900101

Title: Bruce, R.B., L.B. Turnbull, and J.H. Newman, Metabolism of methocarbamol in the rat, dog, and human. J Pharm Sci, 1971. 60(1): p. 104-6.

Title: Sica, D.A., et al., Pharmacokinetics and protein binding of methocarbamol in renal insufficiency and normals. Eur J Clin Pharmacol, 1990. 39(2): p. 193-4.

Title: Yaxin Zhang, et al. Methocarbamol blocks muscular Na v 1.4 channels and decreases isometric force of mouse muscles. Muscle Nerve. 2020 Oct 11.

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