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64211-46-7,MFCD01727545
Catalog No.:AA00IB9A

64211-46-7 | Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate

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10mg
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$165.00   $115.00
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1g
≥98%
in stock  
$168.00   $117.00
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5g
≥98%
in stock  
$496.00   $347.00
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25g
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$1,648.00   $1,153.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IB9A
Chemical Name:
Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate
CAS Number:
64211-46-7
Molecular Formula:
C18H14Cl4N4O4
Molecular Weight:
492.1402
MDL Number:
MFCD01727545
SMILES:
Clc1ccc(c(c1)Cl)CON=C(c1ccc(cc1Cl)Cl)Cn1cncc1.[O-][N+](=O)O
NSC Number:
758958
Properties
Properties
 
Form:
Solid  
MP:
136-138℃  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
506  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  

Downstream Synthesis Route
Literature

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140501

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Ototoxic effect of topical oxiconazole and terbinafine in rats.

Journal: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20120401

Title: Clear-cell papulosis: a rare entity that may be misconstrued pathologically as normal skin.

Journal: Pediatric dermatology 20120101

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Antileishmanial activity of benzocycloalkyl azole oximino ethers: the conformationally constraint analogues of oxiconazole.

Journal: Acta tropica 20110201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Cladophialophora saturnica sp. nov., a new opportunistic species of Chaetothyriales revealed using molecular data.

Journal: Medical mycology 20090201

Title: Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials.

Journal: European journal of medicinal chemistry 20090101

Title: Imidazole antifungals, but not triazole antifungals, increase membrane Zn2+ permeability in rat thymocytes Possible contribution to their cytotoxicity.

Journal: Toxicology 20080627

Title: Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080201

Title: Molecular properties of oxyconazole and tioconazole as the criteria for their bioavailability estimation.

Journal: Acta poloniae pharmaceutica 20080101

Title: Oxime and oxime ether derivatives of 1,4-benzothiazine related to oxiconazole.

Journal: ChemMedChem 20070801

Title: Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial.

Journal: The British journal of dermatology 20070801

Title: Activated pregnenolone X-receptor is a target for ketoconazole and its analogs.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070415

Title: An experience from an outbreak of tinea capitis gladiatorum due to Trichophyton tonsurans.

Journal: Clinical and experimental dermatology 20060301

Title: Spectrophotometric determination of oxiconazole in topical lotion using methyl orange.

Journal: Journal of pharmaceutical and biomedical analysis 20050401

Title: Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women.

Journal: Drug metabolism and drug interactions 20050101

Title: Synthesis, antifungal activity, and molecular modeling studies of new inverted oxime ethers of oxiconazole.

Journal: Journal of medicinal chemistry 20021024

Title: LC method for the analysis of Oxiconazole in pharmaceutical formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20020905

Title: [The in vitro properties of a new hydroxypyridone antimycotic rilopirox, with special reference to its anti-Candida activity].

Journal: The Japanese journal of antibiotics 19990201

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Tags:64211-46-7 Molecular Formula|64211-46-7 MDL|64211-46-7 SMILES|64211-46-7 Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-,O-[(2,4-dichlorophenyl)methyl]oxime, (1Z)-, mononitrate