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88495-63-0,MFCD00866204
Catalog No.:AA00IF1A

88495-63-0 | Butanedioic acid,mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester

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1g
95+%
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$32.00   $22.00
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5g
95+%
in stock  
$78.00   $54.00
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25g
98%
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$277.00   $194.00
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IF1A
Chemical Name:
Butanedioic acid,mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
CAS Number:
88495-63-0
Molecular Formula:
C19H28O8
Molecular Weight:
384.4208
MDL Number:
MFCD00866204
SMILES:
OC(=O)CCC(=O)O[C@H]1O[C@@H]2O[C@@]3(C)CC[C@@H]4[C@]2([C@H]([C@H]1C)CC[C@H]4C)OO3
Properties
Computed Properties
 
Complexity:
623  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
2.5  

Literature

Title: Artesunate ameliorates high glucose-induced rat glomerular mesangial cell injury by suppressing the TLR4/NF-κB/NLRP3 inflammasome pathway.

Journal: Chemico-biological interactions 20180925

Title: Chemoprevention by artesunate in a preclinical model of colorectal cancer involves down regulation of β-catenin, suppression of angiogenesis, cellular proliferation and induction of apoptosis.

Journal: Chemico-biological interactions 20171225

Title: Antimalarial agent artesunate protects Concanavalin A-induced autoimmune hepatitis in mice by inhibiting inflammatory responses.

Journal: Chemico-biological interactions 20170825

Title: Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature.

Journal: Archives of toxicology 20170401

Title: Attenuation of gastric mucosal damage by artesunate in rat: Modulation of oxidative stress and NFκB mediated signaling.

Journal: Chemico-biological interactions 20160925

Title: Untargeted Proteomics and Systems-Based Mechanistic Investigation of Artesunate in Human Bronchial Epithelial Cells.

Journal: Chemical research in toxicology 20151019

Title: Delayed anemia after treatment with injectable artesunate in the Democratic Republic of the Congo: a manageable issue.

Journal: The American journal of tropical medicine and hygiene 20141001

Title: Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate.

Journal: Cell 20140814

Title: Artesunate induces apoptosis through caspase-dependent and -independent mitochondrial pathways in human myelodysplastic syndrome SKM-1 cells.

Journal: Chemico-biological interactions 20140805

Title: Quinoline-pyrimidine hybrids: synthesis, antiplasmodial activity, SAR, and mode of action studies.

Journal: Journal of medicinal chemistry 20140123

Title: Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.

Journal: Bioorganic & medicinal chemistry 20131201

Title: Antimalarial and cytotoxic activities of chiral triamines.

Journal: Bioorganic & medicinal chemistry letters 20130815

Title: Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity.

Journal: Journal of medicinal chemistry 20130808

Title: Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies.

Journal: European journal of medicinal chemistry 20130801

Title: Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis.

Journal: Bioorganic & medicinal chemistry 20130715

Title: In vitro and in vivo characterization of the antimalarial lead compound SSJ-183 in Plasmodium models.

Journal: Drug design, development and therapy 20130101

Title: Artesunate-loaded chitosan/lecithin nanoparticles: preparation, characterization, and in vivo studies.

Journal: Drug development and industrial pharmacy 20121201

Title: Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells.

Journal: Journal of cellular physiology 20121201

Title: Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1-5 years of age.

Journal: The Journal of infectious diseases 20121201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation.

Journal: The Journal of antimicrobial chemotherapy 20121101

Title: Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides.

Journal: Journal of medicinal chemistry 20121025

Title: Adjunctive management of malaria.

Journal: Current opinion in infectious diseases 20121001

Title: Travel and fake artesunate: a risky business.

Journal: Lancet (London, England) 20120922

Title: Primaquine for reducing Plasmodium falciparum transmission.

Journal: The Cochrane database of systematic reviews 20120912

Title: Artesunate for severe acute Plasmodium falciparum infection in a patient with myasthenia gravis.

Journal: The American journal of tropical medicine and hygiene 20120905

Title: Intravenous artesunate for transfusion-transmitted plasmodium vivax malaria in a preterm neonate.

Journal: Pediatrics 20120901

Title: [New combination therapy against malaria].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20120821

Title: A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation.

Journal: Journal of tropical pediatrics 20120801

Title: Severe malaria, artesunate and haemolysis.

Journal: The Journal of antimicrobial chemotherapy 20120801

Title: Development of NIRS method for quality control of drug combination artesunate-azithromycin for the treatment of severe malaria.

Journal: Journal of pharmaceutical and biomedical analysis 20120801

Title: Anti-malarial drug artesunate ameliorates oxidative lung damage in experimental allergic asthma.

Journal: Free radical biology & medicine 20120801

Title: Artesunate- and amodiaquine-associated extrapyramidal reactions: a series of 49 cases in VigiBase™.

Journal: Drug safety 20120801

Title: Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement.

Journal: PLoS medicine 20120801

Title: Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells.

Journal: Anti-cancer drugs 20120701

Title: [Use of intravenous artemisinin derivatives in severe malaria].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20120701

Title: Lamivudine-artesunate co-administration affects glucose metabolism in healthy and diseased wistar rats.

Journal: Pakistan journal of pharmaceutical sciences 20120701

Title: No evidence of decreased artemisinin efficacy in a high-transmission malaria setting in Mali.

Journal: The American journal of tropical medicine and hygiene 20120701

Title: No evidence of delayed parasite clearance after oral artesunate treatment of uncomplicated falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20120701

Title: New treatment policy of malaria as a part of malaria control program in Indonesia.

Journal: Acta medica Indonesiana 20120701

Title: [Immunoregulatory effect of artesunate on allergic contact dermatitis and its mechanism].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120701

Title: Artesunate versus quinine for treating severe malaria.

Journal: The Cochrane database of systematic reviews 20120613

Title: 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.

Journal: European journal of medicinal chemistry 20120601

Title: A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120601

Title: [Treatment of a questionable prostate carcinoma recurrence with oncolytic viruses, dendritic cells and heat shock proteins in established naturopathy practice].

Journal: Versicherungsmedizin 20120601

Title: Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica.

Journal: Veterinary parasitology 20120525

Title: Imidazolopiperazines: lead optimization of the second-generation antimalarial agents.

Journal: Journal of medicinal chemistry 20120510

Title: Artesunate inhibits cell proliferation and decreases growth hormone synthesis and secretion in GH3 cells.

Journal: Molecular biology reports 20120501

Title: Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia.

Journal: Acta tropica 20120501

Title: Fasciola gigantica: the in vitro effects of artesunate as compared to triclabendazole on the 3-weeks-old juvenile.

Journal: Experimental parasitology 20120501

Title: Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120415

Title: Pyronaridine-artesunate versus mefloquine plus artesunate for malaria.

Journal: The New England journal of medicine 20120405

Title: The sensitivity of artesunate against Schistosoma japonicum decreased after 10 years of use in China?

Journal: Parasitology research 20120401

Title: In vitro assessment of drug resistance in Plasmodium falciparum in five States of India.

Journal: The Indian journal of medical research 20120401

Title: [Impact of artesunate on the expression and secretion of transforming growth factor-b1 of primary rat hepatic stellate cells].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20120401

Title: Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects.

Journal: British journal of clinical pharmacology 20120301

Title: High dose artesunate in combination with mefloquine: pharmacovigilance in the Venezuelan Amazon.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20120301

Title: No evidence for spread of Plasmodium falciparum artemisinin resistance to Savannakhet Province, Southern Laos.

Journal: The American journal of tropical medicine and hygiene 20120301

Title: Drug-drug interaction analysis of pyronaridine/artesunate and ritonavir in healthy volunteers.

Journal: The American journal of tropical medicine and hygiene 20120301

Title: Preparation of a single-chain variable fragment and a recombinant antigen-binding fragment against the anti-malarial drugs, artemisinin and artesunate, and their application in an ELISA.

Journal: Analytical chemistry 20120221

Title: Artesunate activates Nrf2 pathway-driven anti-inflammatory potential through ERK signaling in microglial BV2 cells.

Journal: Neuroscience letters 20120210

Title: Linker-based hemisuccinate derivatives of artemisinin: synthesis and antimalarial assessment against multidrug-resistant Plasmodium yoelii nigeriensis in mice.

Journal: Journal of medicinal chemistry 20120209

Title: Rectal artesunates, their utilization, and parental perception in the management of malaria in children from Abeokuta, southwestern Nigeria.

Journal: Vector borne and zoonotic diseases (Larchmont, N.Y.) 20120201

Title: [Effects of artesunate on tumor necrosis factor alpha and chemotactic factors in the serum and the synoviocyte culture supernate of collagen-induced arthritis rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20120201

Title: A simplified intravenous artesunate regimen for severe malaria.

Journal: The Journal of infectious diseases 20120115

Title: Febrifugine analogue compounds: synthesis and antimalarial evaluation.

Journal: Bioorganic & medicinal chemistry 20120115

Title: The antiplasmodial activity of Anogeissus leiocarpus and its effect on oxidative stress and lipid profile in mice infected with Plasmodium bergheii.

Journal: Parasitology research 20120101

Title: Characterization of dihydroartemisinin-resistant colon carcinoma HCT116/R cell line.

Journal: Molecular and cellular biochemistry 20120101

Title: Molecular monitoring of Plasmodium falciparum resistance to antimalarial drugs after adoption of sulfadoxine-pyrimethamine plus artesunate as the first line treatment in Iran.

Journal: Acta tropica 20120101

Title: Molecular assessment of dhfr/dhps mutations among Plasmodium vivax clinical isolates after introduction of sulfadoxine/pyrimethamine in combination with artesunate in Iran.

Journal: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20120101

Title: Randomized, prospective, three-arm study to confirm the auditory safety and efficacy of artemether-lumefantrine in Colombian patients with uncomplicated Plasmodium falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20120101

Title: Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa.

Journal: Malaria journal 20120101

Title: Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP.

Journal: PloS one 20120101

Title: A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans.

Journal: Malaria journal 20120101

Title: Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium.

Journal: Malaria journal 20120101

Title: Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.

Journal: Malaria journal 20120101

Title: Post-treatment haemolysis in severe imported malaria after intravenous artesunate: case report of three patients with hyperparasitaemia.

Journal: Malaria journal 20120101

Title: Examination of the cytotoxic and embryotoxic potential and underlying mechanisms of next-generation synthetic trioxolane and tetraoxane antimalarials.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes.

Journal: PloS one 20120101

Title: Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India.

Journal: Malaria journal 20120101

Title: Pharmacokinetic profiles of artesunate following multiple intravenous doses of 2, 4, and 8 mg/kg in healthy volunteers: phase 1b study.

Journal: Malaria journal 20120101

Title: Deaths due to Plasmodium knowlesi malaria in Sabah, Malaysia: association with reporting as Plasmodium malariae and delayed parenteral artesunate.

Journal: Malaria journal 20120101

Title: Effect of artesunate-mefloquine fixed-dose combination in malaria transmission in Amazon basin communities.

Journal: Malaria journal 20120101

Title: A longitudinal trial comparing chloroquine as monotherapy or in combination with artesunate, azithromycin or atovaquone-proguanil to treat malaria.

Journal: PloS one 20120101

Title: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997-2007.

Journal: Malaria journal 20120101

Title: Artemisinin resistance containment project in Thailand. II: Responses to mefloquine-artesunate combination therapy among falciparum malaria patients in provinces bordering Cambodia.

Journal: Malaria journal 20120101

Title: In vitro action of antiparasitic drugs, especially artesunate, against Toxoplasma gondii.

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20120101

Title: Effects of antimalarial drugs on movement of Plasmodium falciparum.

Journal: The Southeast Asian journal of tropical medicine and public health 20120101

Title: The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model.

Journal: Molecules (Basel, Switzerland) 20111219

Title: Voltammetric behaviour of antimalarial drug artesunate in solubilized systems.

Journal: Colloids and surfaces. B, Biointerfaces 20111201

Title: Artesunate enhances radiosensitivity of human non-small cell lung cancer A549 cells via increasing NO production to induce cell cycle arrest at G2/M phase.

Journal: International immunopharmacology 20111201

Title: Artesunate induces oxidative DNA damage, sustained DNA double-strand breaks, and the ATM/ATR damage response in cancer cells.

Journal: Molecular cancer therapeutics 20111201

Title: Spontaneous acute subdural hematoma in malaria: a case report.

Journal: Journal of vector borne diseases 20111201

Title: Novel orally active antimalarial thiazoles.

Journal: Journal of medicinal chemistry 20111110

Title: The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants.

Journal: Antiviral research 20111101

Title: Acute pancreatitis in a case of falciparum malaria--a rare presentation.

Journal: The Journal of the Association of Physicians of India 20111101

Title: The pharmacogenetics of antimalaria artemisinin combination therapy.

Journal: Expert opinion on drug metabolism & toxicology 20111001

Title: Ultrastructural and real-time microscopic changes in P. falciparum-infected red blood cells following treatment with antimalarial drugs.

Journal: Ultrastructural pathology 20111001

Title: Three unusual presentations of plasmodium vivax malaria.

Journal: Tropical doctor 20111001

Title: Severe malaria: artesunate is now the standard treatment.

Journal: Prescrire international 20111001

Title: The activity of dispiro peroxides against Fasciola hepatica.

Journal: Bioorganic & medicinal chemistry letters 20110915

Title: Responding to the evidence for the management of severe malaria.

Journal: Tropical medicine & international health : TM & IH 20110901

Title: Polymorphisms of molecular markers of antimalarial drug resistance and relationship with artesunate-mefloquine combination therapy in patients with uncomplicated Plasmodium falciparum malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20110901

Title: Refractory pancytopenia and megaloblastic anemia due to falciparum malaria.

Journal: Journal of tropical pediatrics 20110801

Title: Artesunate in combination with oxacillin protect sepsis model mice challenged with lethal live methicillin-resistant Staphylococcus aureus (MRSA) via its inhibition on proinflammatory cytokines release and enhancement on antibacterial activity of oxacillin.

Journal: International immunopharmacology 20110801

Title: Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.

Journal: Parasitology research 20110801

Title: In vitro evaluation of the genotoxic and cytotoxic effects of artesunate, an antimalarial drug, in human lymphocytes.

Journal: Environmental and molecular mutagenesis 20110801

Title: The need for better data about counterfeit drugs in developing countries: a proposed standard research methodology tested in Chennai, India.

Journal: Journal of clinical pharmacy and therapeutics 20110801

Title: Anthelmintic effect of artesunate in experimental heterophyid infection.

Journal: Journal of the Egyptian Society of Parasitology 20110801

Title: Imidazolopiperazines: hit to lead optimization of new antimalarial agents.

Journal: Journal of medicinal chemistry 20110728

Title: Local inhibition of angiogenesis results in an atrophic non-union in a rat osteotomy model.

Journal: European cells & materials 20110706

Title: Artesunate enhances TRAIL-induced apoptosis in human cervical carcinoma cells through inhibition of the NF-κB and PI3K/Akt signaling pathways.

Journal: International journal of oncology 20110701

Title: Distribution of mefloquine in the blood of Thai patients with acute uncomplicated falciparum malaria following administration of therapeutic doses of artesunate.

Journal: European journal of clinical pharmacology 20110701

Title: Effect of oral coadministration of artesunate with ferrous sulfate on rat liver mitochondrial membrane permeability transition.

Journal: Drug and chemical toxicology 20110701

Title: ACTs for the treatment of schistosomiasis.

Journal: The Lancet. Infectious diseases 20110701

Title: Effectiveness of ACTs in cases of resistance to partner drugs.

Journal: The Lancet. Infectious diseases 20110701

Title: Molecular epidemiology of malaria in Cameroon. XXX. sequence analysis of Plasmodium falciparum ATPase 6, dihydrofolate reductase, and dihydropteroate synthase resistance markers in clinical isolates from children treated with an artesunate-sulfadoxine-pyrimethamine combination.

Journal: The American journal of tropical medicine and hygiene 20110701

Title: Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa.

Journal: Bulletin of the World Health Organization 20110701

Title: Quantification of dihydroartemisinin, artesunate and artemisinin in human blood: overcoming the technical challenge of protecting the peroxide bridge.

Journal: Bioanalysis 20110701

Title: Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.

Journal: Emerging infectious diseases 20110701

Title: Lead optimization of aryl and aralkyl amine-based triazolopyrimidine inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with antimalarial activity in mice.

Journal: Journal of medicinal chemistry 20110609

Title: Genotoxicity assessment of the antimalarial compound artesunate in somatic cells of mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110601

Title: Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.

Journal: Antiviral research 20110601

Title: From quinine to artesunate in Africa.

Journal: The Lancet. Infectious diseases 20110601

Title: Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment.

Journal: American journal of therapeutics 20110501

Title: A reporter system for Epstein-Barr virus (EBV) lytic replication: anti-EBV activity of the broad anti-herpesviral drug artesunate.

Journal: Journal of virological methods 20110501

Title: Intravenous artesunate for severe malaria in travelers, Europe.

Journal: Emerging infectious diseases 20110501

Title: Falciparum malaria presenting as subdural hematoma.

Journal: The Journal of the Association of Physicians of India 20110501

Title: Artesunate for severe malaria.

Journal: Lancet (London, England) 20110430

Title: Use artesunate not quinine to treat severe malaria, say experts.

Journal: BMJ (Clinical research ed.) 20110420

Title: Artesunate for severe malaria in African children.

Journal: Lancet (London, England) 20110402

Title: Effect of artesunate and mefloquine in combination on the Fridericia corrected QT intervals in Plasmodium falciparum infected adults from Thailand.

Journal: Tropical medicine & international health : TM & IH 20110401

Title: Artesunate enhances the antibacterial effect of {beta}-lactam antibiotics against Escherichia coli by increasing antibiotic accumulation via inhibition of the multidrug efflux pump system AcrAB-TolC.

Journal: The Journal of antimicrobial chemotherapy 20110401

Title: Artesunate inhibits growth and induces apoptosis in human osteosarcoma HOS cell line in vitro and in vivo.

Journal: Journal of Zhejiang University. Science. B 20110401

Title: Artesunate: investigational drug for the treatment of severe falciparum malaria in Hawai'i.

Journal: Hawaii medical journal 20110401

Title: Parenteral artesunate access programme aims at reducing malaria fatality rates in South Africa.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20110401

Title: Artesunate versus quinine for treating severe malaria.

Journal: The Cochrane database of systematic reviews 20110316

Title: The antimalarial agent artesunate possesses anticancer properties that can be enhanced by combination strategies.

Journal: International journal of cancer 20110315

Title: Artesunate mitigates proliferation of tumor cells by alkylating heme-harboring nitric oxide synthase.

Journal: Nitric oxide : biology and chemistry 20110315

Title: Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers.

Journal: European journal of clinical pharmacology 20110301

Title: The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110301

Title: Artesunate/mefloquine paediatric formulation vs. artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum in Anonkoua kouté, Côte d'Ivoire.

Journal: Tropical medicine & international health : TM & IH 20110301

Title: Drug dispensing practices during implementation of artemisinin-based combination therapy at health facilities in rural Tanzania, 2002-2005.

Journal: Tropical medicine & international health : TM & IH 20110301

Title: Increased prevalence of the Plasmodium falciparum Pfmdr1 86N genotype among field isolates from Franceville, Gabon after replacement of chloroquine by artemether-lumefantrine and artesunate-mefloquine.

Journal: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20110301

Title: Artemisinins act through at least two targets in a yeast model.

Journal: FEMS yeast research 20110301

Title: [In vitro effect of seven anthelmintic agents against adult Clonorchis sinensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110227

Title: Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production.

Journal: The Journal of biological chemistry 20110225

Title: Formation and identification of a degradant in chlorproguanil-dapsone-artesunate (Dacart™) tablets.

Journal: Journal of pharmaceutical and biomedical analysis 20110220

Title: Effect of artesunate on endotoxin-induced uveitis in rats.

Journal: Investigative ophthalmology & visual science 20110216

Title: Azithromycin for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20110216

Title: Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.

Journal: Parasitology research 20110201

Title: Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial.

Journal: The Lancet. Infectious diseases 20110201

Title: Antiviral activity of ganciclovir and artesunate towards human cytomegalovirus in astrocytoma cells.

Journal: Antiviral research 20110201

Title: Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether and their major metabolites dihydroartemisinin and dihydroartemisinin-glucuronide in sheep plasma.

Journal: Journal of mass spectrometry : JMS 20110201

Title: Artesunate and artelinic acid: association of embryotoxicity, reticulocytopenia, and delayed stimulation of hematopoiesis in pregnant rats.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110201

Title: Phenolic glycosides with antimalarial activity from Grevillea 'Poorinda Queen'.

Journal: Journal of natural products 20110128

Title: Artesunate is ineffective in controlling valganciclovir-resistant cytomegalovirus infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110115

Title: The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials.

Journal: The Journal of biological chemistry 20110114

Title: The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte.

Journal: Rheumatology international 20110101

Title: Effects of co-administration of artesunate and amodiaquine on some cardiovascular disease indices in rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101

Title: ART-induced biophysical and biochemical alterations of Jurkat cell membrane.

Journal: Micron (Oxford, England : 1993) 20110101

Title: Antimalarial drug resistance of Plasmodium falciparum in India: changes over time and space.

Journal: The Lancet. Infectious diseases 20110101

Title: Automated erythrocytapheresis for severe falciparum malaria.

Journal: Internal medicine journal 20110101

Title: Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial.

Journal: PloS one 20110101

Title: Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.

Journal: Malaria journal 20110101

Title: Intermittent preventive therapy for malaria: arguments in favour of artesunate and sulphamethoxypyrazine - pyrimethamine combination.

Journal: Malaria journal 20110101

Title: In vitro and in vivo assessment of the anti-malarial activity of Caesalpinia pluviosa.

Journal: Malaria journal 20110101

Title: Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria.

Journal: Malaria journal 20110101

Title: S1P is associated with protection in human and experimental cerebral malaria.

Journal: Molecular medicine (Cambridge, Mass.) 20110101

Title: Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: a randomized clinical trial.

Journal: PloS one 20110101

Title: Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells.

Journal: PloS one 20110101

Title: Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway.

Journal: PloS one 20110101

Title: Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria.

Journal: Malaria journal 20110101

Title: Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro.

Journal: Malaria journal 20110101

Title: In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB/c mice.

Journal: Revista do Instituto de Medicina Tropical de Sao Paulo 20110101

Title: Molecular analysis of pfatp6 and pfmdr1 polymorphisms and their association with in vitro sensitivity in Plasmodium falciparum isolates from the Thai-Myanmar border.

Journal: Acta tropica 20110101

Title: Effect of interaction of magnetic nanoparticles of Fe₃O₄ and artesunate on apoptosis of K562 cells.

Journal: International journal of nanomedicine 20110101

Title: Pre-referral rectal artesunate in severe malaria: flawed trial.

Journal: Trials 20110101

Title: Response to: Pre-referral rectal artesunate in severe malaria: a flawed trial.

Journal: Trials 20110101

Title: Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials.

Journal: Malaria journal 20110101

Title: A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania.

Journal: Malaria journal 20110101

Title: Application of DNA-based diagnostics in detection of schistosomal DNA in early infection and after drug treatment.

Journal: Parasites & vectors 20110101

Title: Treatment of imported severe malaria with artesunate instead of quinine--more evidence needed?

Journal: Malaria journal 20110101

Title: Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali.

Journal: Malaria journal 20110101

Title: The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination.

Journal: Malaria journal 20110101

Title: Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei.

Journal: PloS one 20110101

Title: Expression of p53 in the effects of artesunate on induction of apoptosis and inhibition of proliferation in rat primary hepatic stellate cells.

Journal: PloS one 20110101

Title: Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator.

Journal: Malaria journal 20110101

Title: Inhaled nitric oxide reduces endothelial activation and parasite accumulation in the brain, and enhances survival in experimental cerebral malaria.

Journal: PloS one 20110101

Title: Impact of combining intermittent preventive treatment with home management of malaria in children less than 10 years in a rural area of Senegal: a cluster randomized trial.

Journal: Malaria journal 20110101

Title: Effects of the antimalarial drugs ferroquine and artesunate on Plasmodium yoelii yoelii gametocytegenesis and vectorial transmission.

Journal: Sante (Montrouge, France) 20110101

Title: Dose-dependent risk of neutropenia after 7-day courses of artesunate monotherapy in Cambodian patients with acute Plasmodium falciparum malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101215

Title: A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos.

Journal: The American journal of tropical medicine and hygiene 20101206

Title: Prereferral rectal artesunate for treatment of severe childhood malaria: a cost-effectiveness analysis.

Journal: Lancet (London, England) 20101204

Title: Cost-effective use of prereferral treatment for severe malaria.

Journal: Lancet (London, England) 20101204

Title: Oral artesunate for neonatal malaria.

Journal: Journal of tropical pediatrics 20101201

Title: In vitro activity of pyronaridine against multidrug-resistant Plasmodium falciparum and Plasmodium vivax.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Alternative visual displays of metaanalysis of malaria treatment trials to facilitate translation of research into policy.

Journal: Diagnostic microbiology and infectious disease 20101201

Title: A simplified liquid chromatography-mass spectrometry assay for artesunate and dihydroartemisinin, its metabolite, in human plasma.

Journal: Molecules (Basel, Switzerland) 20101201

Title: For severe malaria, artesunate is the answer.

Journal: Lancet (London, England) 20101113

Title: Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial.

Journal: Lancet (London, England) 20101113

Title: Waking the sleeping beauty.

Journal: The Journal of infectious diseases 20101101

Title: Artesunate inhibiting angiogenesis induced by human myeloma RPMI8226 cells.

Journal: International journal of hematology 20101101

Title: Purpura fulminans: a rare presentation of a common disease.

Journal: Tropical doctor 20101001

Title: Localization of artesunate and its derivatives in the pregnant rat and fetus following oral administration and relationship to developmental toxicity.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20101001

Title: Comparison of artesunate and quinine in the treatment of Sudanese children with severe Plasmodium falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20101001

Title: Artesunate misuse and Plasmodium falciparum malaria in traveler returning from Africa.

Journal: Emerging infectious diseases 20101001

Title: Artemether-Lumefantrin (Coartem) and artesunate with sulfadoxine-pyrimethamine therapeutic efficacy in the treatment of uncomplicated malaria at Gilgel Gibe II (GGII) South-Western Ethiopia.

Journal: Ethiopian medical journal 20101001

Title: Spiroindolones, a potent compound class for the treatment of malaria.

Journal: Science (New York, N.Y.) 20100903

Title: First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases.

Journal: International journal of cancer 20100901

Title: Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis.

Journal: Parasitology international 20100901

Title: Artesunate, a potential drug for treatment of Babesia infection.

Journal: Parasitology international 20100901

Title: Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: The sensitivity of artesunate against Schistosoma japonicum decreased after 10 years of use in China.

Journal: Parasitology research 20100901

Title: Efficacy of artesunate with sulfalene plus pyrimethamine versus praziquantel for treatment of Schistosoma mansoni in Kenyan children: an open-label randomised controlled trial.

Journal: The Lancet. Infectious diseases 20100901

Title: Comparative study of efficacy of artesunate plus cotrimoxazole and artesunate plus chloroquine in the treatment of malaria in Nigerian children: a preliminary report.

Journal: Journal of vector borne diseases 20100901

Title: Artesunate-clindamycin multi-kinetics and site-specific oral delivery system for antimalaric combination products.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20100817

Title: Azithromycin combination therapy for the treatment of uncomplicated falciparum malaria in Bangladesh: an open-label randomized, controlled clinical trial.

Journal: The Journal of infectious diseases 20100815

Title: Combined intravenous treatment with artesunate and quinine for severe malaria in Italy.

Journal: The American journal of tropical medicine and hygiene 20100805

Title: Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.

Journal: Journal of medicinal chemistry 20100722

Title: Cytotoxicity of artesunic acid homo- and heterodimer molecules toward sensitive and multidrug-resistant CCRF-CEM leukemia cells.

Journal: Journal of medicinal chemistry 20100708

Title: Effects of artemisinin derivative on the growth metabolism of Tetrahymena thermophila BF5 based on expression of thermokinetics.

Journal: Biological trace element research 20100701

Title: Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia.

Journal: The American journal of tropical medicine and hygiene 20100701

Title: Dynamics of Plasmodium falciparum parasitemia regarding combined treatment regimens for acute uncomplicated malaria, Antioquia, Colombia.

Journal: The American journal of tropical medicine and hygiene 20100701

Title: [Treatment of rats infected with Clonorchis sinensis using clinical administration regimens of tribendimidine, praziquantel and artesunate].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20100630

Title: Tolerability and efficacy of a pediatric granule formulation of artesunate-mefloquine in young children from Cameroon with uncomplicated falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20100601

Title: Artesunate suppositories: an option for severe malaria.

Journal: Prescrire international 20100601

Title: Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica.

Journal: Journal of medicinal chemistry 20100527

Title: Multiple genetic backgrounds of the amplified Plasmodium falciparum multidrug resistance (pfmdr1) gene and selective sweep of 184F mutation in Cambodia.

Journal: The Journal of infectious diseases 20100515

Title: [A new antimalarial drug combination].

Journal: Revue medicale suisse 20100505

Title: Successful introduction of artesunate combination therapy is not enough to fight malaria: results from an adherence study in Sierra Leone.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20100501

Title: Toxicity of the antimalarial artemisinin and its dervatives.

Journal: Critical reviews in toxicology 20100501

Title: Non-animal sensitization testing: state-of-the-art.

Journal: Critical reviews in toxicology 20100501

Title: In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100501

Title: Five years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique.

Journal: The American journal of tropical medicine and hygiene 20100501

Title: Pyronaridine-artesunate for uncomplicated falciparum malaria.

Journal: Lancet (London, England) 20100424

Title: Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial.

Journal: Lancet (London, England) 20100424

Title: Pharmacogenomic identification of c-Myc/Max-regulated genes associated with cytotoxicity of artesunate towards human colon, ovarian and lung cancer cell lines.

Journal: Molecules (Basel, Switzerland) 20100422

Title: Factors determining sensitivity or resistance of tumor cell lines towards artesunate.

Journal: Chemico-biological interactions 20100415

Title: Artesunate induces oncosis-like cell death in vitro and has antitumor activity against pancreatic cancer xenografts in vivo.

Journal: Cancer chemotherapy and pharmacology 20100401

Title: Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisinin.

Journal: Experimental parasitology 20100401

Title: Effects of ethanol extract of Artemisia annua L. against monogenean parasites of Heterobranchus longifilis.

Journal: Parasitology research 20100401

Title: Severe congenital malaria acquired in utero.

Journal: The American journal of tropical medicine and hygiene 20100401

Title: Traditional Chinese medicine and related active compounds against hepatitis B virus infection.

Journal: Bioscience trends 20100401

Title: Cervical lymphadenopathy: a rare presentation of malaria.

Journal: The Journal of the Association of Physicians of India 20100401

Title: Management of malaria and other severe infections in rural Africa and Asia.

Journal: BMJ (Clinical research ed.) 20100317

Title: Design of a fixed-dose paediatric combination of artesunate and amodiaquine hydrochloride.

Journal: International journal of pharmaceutics 20100315

Title: The effect of point mutations in dihydrofolate reductase genes and multidrug resistance gene 1-86 on treatment of falciparum malaria in Sudan.

Journal: Journal of infection in developing countries 20100308

Title: Artesunate protects sepsis model mice challenged with Staphylococcus aureus by decreasing TNF-alpha release via inhibition TLR2 and Nod2 mRNA expressions and transcription factor NF-kappaB activation.

Journal: International immunopharmacology 20100301

Title: Cardiac function and hemodynamics in Kenyan children with severe malaria.

Journal: Critical care medicine 20100301

Title: Traditional Chinese medicines (TCMs) for molecular targeted therapies of tumours.

Journal: Current drug discovery technologies 20100301

Title: Is it too soon to eliminate quinine?

Journal: The Lancet. Infectious diseases 20100301

Title: A controlled trial to assess the effect of quinine, chloroquine, amodiaquine, and artesunate on Loa loa microfilaremia.

Journal: The American journal of tropical medicine and hygiene 20100301

Title: Plasmodium vivax with acute glomerulonephritis in an 8-year old.

Journal: Journal of vector borne diseases 20100301

Title: Efficacy and safety of a new pediatric artesunate-mefloquine drug formulation for the treatment of uncomplicated falciparum malaria in Gabon.

Journal: Wiener klinische Wochenschrift 20100301

Title: Symmetrical peripheral gangrene in childhood falciparum malaria.

Journal: International journal of dermatology 20100301

Title: Anthelmintic activity of artesunate against Fasciola hepatica in naturally infected sheep.

Journal: Research in veterinary science 20100201

Title: Ursodeoxycholic acid and artesunate in the treatment of severe falciparum malaria patients with jaundice.

Journal: Journal of gastroenterology and hepatology 20100201

Title: Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate.

Journal: Acta tropica 20100201

Title: Artemisinin derivatives for treatment of uncomplicated Plasmodium falciparum malaria in Sudan: too early for too much hope.

Journal: Parasitology research 20100201

Title: The use of placebo in a trial of rectal artesunate as initial treatment for severe malaria patients en route to referral clinics: ethical issues.

Journal: Journal of medical ethics 20100201

Title: Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.

Journal: Journal of medicinal chemistry 20100128

Title: Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.

Journal: Biochemical pharmacology 20100115

Title: The comparative antimalarial properties of weak base and neutral synthetic ozonides.

Journal: Bioorganic & medicinal chemistry letters 20100115

Title: The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).

Journal: Journal of medicinal chemistry 20100114

Title: Investigation of porous graphitic carbon at high-temperature liquid chromatography with evaporative light scattering detection for the analysis of the drug combination artesunate--azithromycin for the treatment of severe malaria.

Journal: Journal of chromatography. A 20100101

Title: A randomized trial of artesunate mefloquine versus artemether lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Senegalese children.

Journal: The American journal of tropical medicine and hygiene 20100101

Title: Activation-induced T helper cell death contributes to Th1/Th2 polarization following murine Schistosoma japonicum infection.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Efficacy and safety of quinine-artesunate in an HIV-positive patient with severe falciparum malaria.

Journal: Minerva anestesiologica 20100101

Title: Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.

Journal: PloS one 20100101

Title: Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria.

Journal: Malaria journal 20100101

Title: Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate.

Journal: PloS one 20100101

Title: Understanding caretakers' dilemma in deciding whether or not to adhere with referral advice after pre-referral treatment with rectal artesunate.

Journal: Malaria journal 20100101

Title: Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs.

Journal: Malaria journal 20100101

Title: Intravenous artesunate for the treatment of severe malaria.

Journal: The Annals of pharmacotherapy 20100101

Title: Monitoring for Plasmodium falciparum drug resistance to artemisinin and artesunate in Binh Phuoc Province, Vietnam: 1998-2009.

Journal: Malaria journal 20100101

Title: An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia.

Journal: PloS one 20100101

Title: Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.

Journal: PloS one 20100101

Title: Cost effectiveness of seasonal intermittent preventive treatment using amodiaquine & artesunate or sulphadoxine-pyrimethamine in Ghanaian children.

Journal: PloS one 20100101

Title: Declining in efficacy of a three-day combination regimen of mefloquine-artesunate in a multi-drug resistance area along the Thai-Myanmar border.

Journal: Malaria journal 20100101

Title: Firstborn microcrystallization method to prepare nanocapsules containing artesunate.

Journal: International journal of nanomedicine 20100101

Title: Artesunate-mefloquine combination therapy in acute Plasmodium falciparum malaria in young children: a field study regarding neurological and neuropsychiatric safety.

Journal: Malaria journal 20100101

Title: Modulating effects of plasma containing anti-malarial antibodies on in vitro anti-malarial drug susceptibility in Plasmodium falciparum.

Journal: Malaria journal 20100101

Title: Knowledge and acceptability of the rectal treatment route in Laos and its application for pre-referral emergency malaria treatment.

Journal: Malaria journal 20100101

Title: Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.

Journal: Cancer genomics & proteomics 20100101

Title: Immunological consequences of intermittent preventive treatment against malaria in Senegalese preschool children.

Journal: Malaria journal 20100101

Title: An open randomized clinical trial in comparing two artesunate-based combination treatments on Plasmodium falciparum malaria in Nigerian children: artesunate/sulphamethoxypyrazine/pyrimethamine (fixed dose over 24 hours) versus artesunate/amodiaquine (fixed dose over 48 hours).

Journal: Malaria journal 20100101

Title: Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach.

Journal: Journal of medicinal chemistry 20091224

Title: High performance liquid chromatographic evaluation of artemisinin, raw material in the synthesis of artesunate and artemether.

Journal: Journal of chromatography. A 20091218

Title: Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits.

Journal: Parasitology research 20091201

Title: A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity.

Journal: European journal of medicinal chemistry 20091201

Title: Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda.

Journal: The Journal of infectious diseases 20091201

Title: Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20091201

Title: Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria.

Journal: The American journal of tropical medicine and hygiene 20091201

Title: A pilot study of the therapeutic efficacy and mechanism of artesunate in the MRL/lpr murine model of systemic lupus erythematosus.

Journal: Cellular & molecular immunology 20091201

Title: Comparative study of artesunate, ACTs and their combinants on the hormonal parameters of the male guinea pig.

Journal: Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20091201

Title: New perspectives of malaria control in India under World Bank Project.

Journal: Journal of the Indian Medical Association 20091201

Title: Effect of artesunate on inhibiting proliferation and inducing apoptosis of SP2/0 myeloma cells through affecting NFkappaB p65.

Journal: International journal of hematology 20091101

Title: Effect of artesunate on immune cells in ret-transgenic mouse melanoma model.

Journal: Anti-cancer drugs 20091101

Title: [Inhibitive effect of artesunate on human lymphoblastic leukemia/lymphoma cells].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101

Title: Early diagnosis and treatment of falciparum malaria in Cambodian trauma patients.

Journal: The Southeast Asian journal of tropical medicine and public health 20091101

Title: Azithromycin plus artesunate versus artemether-lumefantrine for treatment of uncomplicated malaria in Tanzanian children: a randomized, controlled trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20091015

Title: Artesunate plus sulfadoxine/pyrimethamine versus praziquantel in the treatment of Schistosoma mansoni in eastern Sudan.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20091001

Title: Artesunate plus sulfamethoxypyrazine/pyrimethamine for the treatment of cutaneous leishmaniasis: a double-blind, placebo-controlled clinical trial.

Journal: International journal of antimicrobial agents 20091001

Title: Pharmacokinetics of chlorproguanil, dapsone, artesunate and their major metabolites in patients during treatment of acute uncomplicated Plasmodium falciparum malaria.

Journal: European journal of clinical pharmacology 20091001

Title: Artemisone and artemiside control acute and reactivated toxoplasmosis in a murine model.

Journal: Antimicrobial agents and chemotherapy 20091001

Title: Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Pharmacokinetic profiles of artesunate after single intravenous doses at 0.5, 1, 2, 4, and 8 mg/kg in healthy volunteers: a phase I study.

Journal: The American journal of tropical medicine and hygiene 20091001

Title: Severe embryolethality of artesunate related to pharmacokinetics following intravenous and intramuscular doses in pregnant rats.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20091001

Title: Sensitivity of human herpesvirus 6 and other human herpesviruses to the broad-spectrum antiinfective drug artesunate.

Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20090901

Title: Comparative study of dihydroartemisinin and artesunate safety in healthy Thai volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20090901

Title: [Effects of Artesunate on MCP-1 and MCP-1 mRNA expression of renal tissue in the rat IgA nephropathy model].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901

Title: Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells.

Journal: Biochemical pharmacology 20090801

Title: Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers.

Journal: European journal of clinical pharmacology 20090801

Title: Artemisinin resistance in Plasmodium falciparum malaria.

Journal: The New England journal of medicine 20090730

Title: Artemisinin-based combination therapy for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20090708

Title: Comparison of sulfadoxine-pyrimethamine, unsupervised artemether-lumefantrine, and unsupervised artesunate-amodiaquine fixed-dose formulation for uncomplicated plasmodium falciparum malaria in Benin: a randomized effectiveness noninferiority trial.

Journal: The Journal of infectious diseases 20090701

Title: Factors influencing adherence to referral advice following pre-referral treatment with artesunate suppositories in children in rural Tanzania.

Journal: Tropical medicine & international health : TM & IH 20090701

Title: Intermittent preventive treatment using artemisinin-based combination therapy reduces malaria morbidity among school-aged children in Mali.

Journal: Tropical medicine & international health : TM & IH 20090701

Title: Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate.

Journal: International journal of oncology 20090701

Title: Drug resistance and in vitro susceptibility of Plasmodium falciparum in Thailand during 1988-2003.

Journal: The Korean journal of parasitology 20090601

Title: Comparative study of artesunate, ACTs and their combinants on the spermatic parameters of the male guinea pig.

Journal: Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20090601

Title: [Therapeutic effect of tribendimidine, artesunate and praziquantel administered to hamsters infected with Clonorchis sinensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20090601

Title: [Therapeutic efficacy of a regimen of artesunate-mefloquine-primaquine treatment for Plasmodium falciparum malaria and treatment effects on gametocytic development].

Journal: Biomedica : revista del Instituto Nacional de Salud 20090601

Title: Pre-referral artesunate in severe malaria.

Journal: Lancet (London, England) 20090523

Title: High prevalence of CYP2A6*4 and CYP2A6*9 alleles detected among a Malaysian population.

Journal: Clinica chimica acta; international journal of clinical chemistry 20090501

Title: Quantification of artemisinin in human plasma using liquid chromatography coupled to tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20090405

Title: Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.

Journal: Experimental parasitology 20090401

Title: Targeted delivery of compounds to Trypanosoma brucei using the melamine motif.

Journal: Bioorganic & medicinal chemistry 20090315

Title: In vitro effects of artesunate on the survival of worm pairs and egg production of Schistosoma mansoni.

Journal: Journal of helminthology 20090301

Title: Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with Fasciola hepatica.

Journal: The Journal of antimicrobial chemotherapy 20090301

Title: Cost-effectiveness of artesunate for the treatment of severe malaria.

Journal: Tropical medicine & international health : TM & IH 20090301

Title: [Experimental study progress on tribendimidine, artemether and artesunate against Clonorchis sinensis and other trematodes].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20090227

Title: Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215

Title: Pre-referral rectal artesunate in severe malaria.

Journal: Lancet (London, England) 20090214

Title: Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial.

Journal: Lancet (London, England) 20090214

Title: Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia.

Journal: Acta tropica 20090201

Title: N-acetylcysteine as adjunctive treatment in severe malaria: a randomized, double-blinded placebo-controlled clinical trial.

Journal: Critical care medicine 20090201

Title: Childhood cerebral vivax malaria with pancytopenia.

Journal: Journal of pediatric hematology/oncology 20090201

Title: The role of downstream signaling pathways of the epidermal growth factor receptor for Artesunate's activity in cancer cells.

Journal: Current cancer drug targets 20090201

Title: [Cerebral malaria].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090201

Title: Malaria - change in therapeutic policy.

Journal: The Indian journal of medical research 20090201

Title: Advances in global biotechnology and local resources to treat malaria.

Journal: Minnesota medicine 20090201

Title: Anaphylactic reaction to intravenous artesunate.

Journal: The Journal of the Association of Physicians of India 20090201

Title: Efficacy of a combination of praziquantel and artesunate in the treatment of urinary schistosomiasis in Nigeria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20090101

Title: Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children.

Journal: Acta tropica 20090101

Title: [Two cases of fulminant hepatitis during a curative treatment with an artesunate-amodiaquine combination].

Journal: Medecine et maladies infectieuses 20090101

Title: Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal.

Journal: Tropical medicine & international health : TM & IH 20090101

Title: Determination of artesunate using reversed-phase HPLC at increased temperature and ELSD detection.

Journal: Journal of separation science 20090101

Title: Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria in southern Cambodia.

Journal: Malaria journal 20090101

Title: Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia.

Journal: Malaria journal 20090101

Title: Does artesunate prolong the electrocardiograph QT interval in patients with severe malaria?

Journal: The American journal of tropical medicine and hygiene 20090101

Title: [Parenteral combined quinine-artesunate therapy in life-threatening malaria].

Journal: Deutsche medizinische Wochenschrift (1946) 20090101

Title: Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya.

Journal: PloS one 20090101

Title: Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment.

Journal: PloS one 20090101

Title: Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa.

Journal: Malaria journal 20090101

Title: Artesunate induced morphological and mechanical changes of Jurkat cell studied by AFM.

Journal: Scanning 20090101

Title: Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.

Journal: PloS one 20090101

Title: Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria.

Journal: Malaria journal 20090101

Title: Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial.

Journal: Malaria journal 20090101

Title: In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays.

Journal: Malaria journal 20090101

Title: Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial.

Journal: PloS one 20090101

Title: Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial.

Journal: Malaria journal 20090101

Title: A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR - implications for therapeutic failure and drug resistance.

Journal: Malaria journal 20090101

Title: Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies.

Journal: Malaria journal 20090101

Title: Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria.

Journal: PloS one 20090101

Title: Population pharmacokinetics of artesunate and amodiaquine in African children.

Journal: Malaria journal 20090101

Title: The neurological assessment in young children treated with artesunate monotherapy or artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum malaria.

Journal: Malaria journal 20090101

Title: Bioavailability of a co-formulated combination of amodiaquine and artesunate under fed and fasted conditions. A randomised, open-label crossover study.

Journal: Arzneimittel-Forschung 20090101

Title: Efficacy of artesunate + sulfamethoxypyrazine/pyrimethamine versus praziquantel in the treatment of Schistosoma haematobium in children.

Journal: PloS one 20090101

Title: [Availability of antimalarial agents in Dutch hospitals].

Journal: Nederlands tijdschrift voor geneeskunde 20090101

Title: Deblurring molecular images using desorption electrospray ionization mass spectrometry.

Journal: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20090101

Title: Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control.

Journal: Malaria journal 20090101

Title: Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children.

Journal: Malaria journal 20090101

Title: Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects.

Journal: Malaria journal 20090101

Title: Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT) following oral administration in African malaria patients.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: A trial of combination antimalarial therapies in children from Papua New Guinea.

Journal: The New England journal of medicine 20081211

Title: Single-dose pharmacokinetic interaction between artesunate and amodiaquine: assembling the clues for the purported interaction.

Journal: European journal of clinical pharmacology 20081201

Title: A liquid chromatographic-tandem mass spectrometric method for determination of artesunate and its metabolite dihydroartemisinin in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081201

Title: Progress in research on the anti-tumor effect of artesunate.

Journal: Chinese journal of integrative medicine 20081201

Title: [Artesunate suppresses human endometrial carcinoma RL95-2 cell proliferation by inducing cell apoptosis].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081201

Title: Evidence for the spectroscopic determination of artesunate in dosage form.

Journal: Journal of vector borne diseases 20081201

Title: A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy.

Journal: PLoS medicine 20081201

Title: Detecting counterfeit antimalarial tablets by near-infrared spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis 20081104

Title: The distribution pattern of intravenous [(14)C] artesunate in rat tissues by quantitative whole-body autoradiography and tissue dissection techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20081104

Title: Lack of multiple copies of pfmdr1 gene in Papua New Guinea.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101

Title: Severe malaria and artesunate treatment, Norway.

Journal: Emerging infectious diseases 20081101

Title: A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20081101

Title: dhfr and dhps genotype and sulfadoxine-pyrimethamine treatment failure in children with falciparum malaria in the Democratic Republic of Congo.

Journal: Tropical medicine & international health : TM & IH 20081101

Title: Development and validation of a liquid chromatography-mass spectrometry method for the simultaneous quantification of artesunate and dihydroartemisinin in human plasma.

Journal: The Southeast Asian journal of tropical medicine and public health 20081101

Title: [Artesunate in interrupting the transmission of Plasmodium falciparum].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20081030

Title: [Effect of tribendimidine, artesunate, artemether and praziquantel, administered intragastrically at single, multiple or combined doses, to rats infected with Clonorchis sinensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20081030

Title: Absence of time-dependent artesunate pharmacokinetics in healthy subjects during 5-day oral administration.

Journal: European journal of clinical pharmacology 20081001

Title: A randomized, comparative study of supervised and unsupervised artesunate-amodiaquine, for the treatment of uncomplicated malaria in Ghana.

Journal: Annals of tropical medicine and parasitology 20081001

Title: Molecular surveillance for multidrug-resistant Plasmodium falciparum, Cambodia.

Journal: Emerging infectious diseases 20081001

Title: Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon.

Journal: The Journal of infectious diseases 20080915

Title: The antiviral activities of artemisinin and artesunate.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080915

Title: Pharmacokinetics of artesunate in the domestic pig.

Journal: The Journal of antimicrobial chemotherapy 20080901

Title: Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080901

Title: Rare presentation of a common disease of tropics.

Journal: The Journal of the Association of Physicians of India 20080901

Title: Assessment of hand-held Raman instrumentation for in situ screening for potentially counterfeit artesunate antimalarial tablets by FT-Raman spectroscopy and direct ionization mass spectrometry.

Journal: Analytica chimica acta 20080815

Title: Sensitive periods for developmental toxicity of orally administered artesunate in the rat.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20080801

Title: Embryotoxicity of artesunate in animal species related to drug tissue distribution and toxicokinetic profiles.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20080801

Title: Artesunate: developmental toxicity and toxicokinetics in monkeys.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20080801

Title: Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20080801

Title: [Suppressive effect of artesunate on K562 cell growth and its influence on VEGF expression].

Journal: Zhongguo shi yan xue ye xue za zhi 20080801

Title: Artesunate for malaria.

Journal: The New England journal of medicine 20080717

Title: Artesunate for malaria.

Journal: The New England journal of medicine 20080717

Title: Artesunate for malaria.

Journal: The New England journal of medicine 20080717

Title: Artesunate for malaria.

Journal: The New England journal of medicine 20080717

Title: Activities of artesunate and amodiaquine against intestinal helminth in children with Plasmodium falciparum malaria in endemic areas.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080701

Title: Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers.

Journal: European journal of clinical pharmacology 20080701

Title: Pharmacokinetic and pharmacodynamic evaluation of intramuscular artesunate in healthy beagle dogs.

Journal: The American journal of tropical medicine and hygiene 20080701

Title: Surveillance for adverse drug reactions to combination antimalarial therapy with sulfadoxine-pyrimethamine plus artesunate in Peru.

Journal: The American journal of tropical medicine and hygiene 20080701

Title: Differential sensitivity of colorectal cancer cell lines to artesunate is associated with expression of beta-catenin and E-cadherin.

Journal: European journal of pharmacology 20080624

Title: Same-single-cell analysis for the study of drug efflux modulation of multidrug resistant cells using a microfluidic chip.

Journal: Analytical chemistry 20080601

Title: Artesunate derived from traditional Chinese medicine induces DNA damage and repair.

Journal: Cancer research 20080601

Title: Gametocyte clearance in uncomplicated and severe Plasmodium falciparum malaria after artesunate-mefloquine treatment in Thailand.

Journal: The Korean journal of parasitology 20080601

Title: [Artesunate induces prostate cancer cell line PC-3 differentiation and cell cycle arrest].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080601

Title: Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080601

Title: [Gametocytemia in falciparum malaria treated with amodiaquine or artesunate].

Journal: Biomedica : revista del Instituto Nacional de Salud 20080601

Title: Purpura fulminans in a complicated Falciparum malaria.

Journal: The Journal of the Association of Physicians of India 20080601

Title: IV artesunate for severe malaria.

Journal: The Medical letter on drugs and therapeutics 20080519

Title: Comparison of HPLC with electrochemical detection and LC-MS/MS for the separation and validation of artesunate and dihydroartemisinin in animal and human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515

Title: A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20080501

Title: High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria.

Journal: Tropical medicine & international health : TM & IH 20080501

Title: Electronically stabilized versions of the antimalarial acetal trioxanes artemether and artesunate.

Journal: Bioorganic & medicinal chemistry 20080501

Title: Artesunate-erythropoietin combination for murine cerebral malaria treatment.

Journal: Acta tropica 20080501

Title: Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080501

Title: Artesunate for the treatment of severe falciparum malaria.

Journal: The New England journal of medicine 20080424

Title: New combined pill to treat malaria is launched.

Journal: BMJ (Clinical research ed.) 20080419

Title: In vitro release and stability of an artesunate rectal gel suitable for pediatric use.

Journal: International journal of pharmaceutics 20080402

Title: High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401

Title: Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401

Title: Effect of artesunate on Toxoplasma gondii: in vitro and in vivo studies.

Journal: Journal of the Egyptian Society of Parasitology 20080401

Title: Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.

Journal: Journal of medicinal chemistry 20080313

Title: Chorea in a 29-year-old Nigerian following antimalarial treatment with artesunate.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20080301

Title: Direct quantitation of active ingredients in solid artesunate antimalarials by noncovalent complex forming reactive desorption electrospray ionization mass spectrometry.

Journal: Journal of the American Society for Mass Spectrometry 20080301

Title: Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kappa B activation.

Journal: International immunopharmacology 20080301

Title: Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.

Journal: Acta tropica 20080301

Title: Optimization of an LC-MS method for the determination of artesunate and dihydroartemisinin plasma levels using liquid-liquid extraction.

Journal: Journal of analytical toxicology 20080301

Title: A randomized controlled pilot study of artesunate versus triclabendazole for human fascioliasis in central Vietnam.

Journal: The American journal of tropical medicine and hygiene 20080301

Title: Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali.

Journal: The American journal of tropical medicine and hygiene 20080301

Title: In vitro bioequivalence study of nine brands of artesunate tablets marketed in Nigeria.

Journal: Journal of vector borne diseases 20080301

Title: Host vascular endothelial growth factor is trophic for Plasmodium falciparum-infected red blood cells.

Journal: Asian Pacific journal of allergy and immunology 20080301

Title: Orally active esters of dihydroartemisinin: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in mice.

Journal: Bioorganic & medicinal chemistry letters 20080215

Title: Fasciola hepatica: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether.

Journal: Experimental parasitology 20080201

Title: [Artesunate combined with vinorelbine plus cisplatin in treatment of advanced non-small cell lung cancer: a randomized controlled trial].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080201

Title: A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia.

Journal: PLoS medicine 20080201

Title: Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6.

Journal: Tropical medicine & international health : TM & IH 20080201

Title: The antischistosomal efficacies of artesunate-sulfamethoxypyrazine-pyrimethamine and artemether-lumefantrine administered as treatment for uncomplicated, Plasmodium falciparum malaria.

Journal: Annals of tropical medicine and parasitology 20080101

Title: Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria.

Journal: Malaria journal 20080101

Title: Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy.

Journal: Malaria journal 20080101

Title: Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso.

Journal: PloS one 20080101

Title: Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria.

Journal: PloS one 20080101

Title: Clinically uncomplicated Plasmodium falciparum malaria with high schizontaemia: a case report.

Journal: Malaria journal 20080101

Title: Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population.

Journal: Malaria journal 20080101

Title: Clinical significance of sequestration in adults with severe malaria.

Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20080101

Title: Acute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: case report and review of literature.

Journal: Malaria journal 20080101

Title: Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children.

Journal: Malaria journal 20080101

Title: Efficacy of Artequick versus artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20080101

Title: An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.

Journal: PloS one 20080101

Title: [In vitro susceptibility of P. falciparum isolates from Abidjan (Côte d'Ivoire) to quinine, artesunate and chloroquine].

Journal: Sante (Montrouge, France) 20080101

Title: Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.

Journal: Malaria journal 20080101

Title: Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate.

Journal: BMC genomics 20080101

Title: Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria.

Journal: Malaria journal 20080101

Title: Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.

Journal: Malaria journal 20080101

Title: Auditory assessment of patients with acute uncomplicated Plasmodium falciparum malaria treated with three-day mefloquine-artesunate on the north-western border of Thailand.

Journal: Malaria journal 20080101

Title: Artesunate causes relaxation of rat aortic rings and reduces the contractile response to noradrenaline.

Journal: Nigerian quarterly journal of hospital medicine 20080101

Title: Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.

Journal: PloS one 20080101

Title: High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency.

Journal: PloS one 20080101

Title: Assessment of the relative advantage of various artesunate-based combination therapies by a multi-treatment Bayesian random-effects meta-analysis.

Journal: The American journal of tropical medicine and hygiene 20071201

Title: Sulfadoxine-pyrimethamine plus artesunate compared with chloroquine for the treatment of vivax malaria in areas co-endemic for Plasmodium falciparum and P. vivax: a randomised non-inferiority trial in eastern Afghanistan.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20071101

Title: Characterization of genuine and fake artesunate anti-malarial tablets using Fourier transform infrared imaging and spatially offset Raman spectroscopy through blister packs.

Journal: Analytical and bioanalytical chemistry 20071101

Title: Pharmacokinetics of two paediatric artesunate mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon.

Journal: The Journal of antimicrobial chemotherapy 20071101

Title: Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.

Journal: Clinical pharmacology and therapeutics 20071101

Title: Dynamics of asymptomatic Plasmodium vivax infections and Duffy binding protein polymorphisms in relation to parasitemia levels in Papua New Guinean children.

Journal: The American journal of tropical medicine and hygiene 20071101

Title: Clinical symptoms, treatment and outcome of highlands malaria in Eldoret (2420 m a.s.l.) and comparison to malaria in hyper-immune population in endemic region of Southern Sudan.

Journal: Neuro endocrinology letters 20071101

Title: Artesunate versus quinine for treating severe malaria.

Journal: The Cochrane database of systematic reviews 20071017

Title: Resistance to artemisinin derivatives along the Thai-Cambodian border.

Journal: Releve epidemiologique hebdomadaire 20071012

Title: Artesunate and dihydroartemisinin (DHA): unusual decomposition products formed under mild conditions and comments on the fitness of DHA as an antimalarial drug.

Journal: ChemMedChem 20071001

Title: An analytical method with a single extraction procedure and two separate high performance liquid chromatographic systems for the determination of artesunate, dihydroartemisinin and mefloquine in human plasma for application in clinical pharmacological studies of the drug combination.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001

Title: Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine: artesunate plus sulfadoxine/pyrimethamine versus artesunate plus sulfamethoxypyrazine/pyrimethamine.

Journal: The American journal of tropical medicine and hygiene 20071001

Title: Validation and application of a liquid chromatographic-mass spectrometric method for determination of artesunate in pharmaceutical samples.

Journal: Journal of pharmaceutical and biomedical analysis 20070921

Title: Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway.

Journal: International journal of cancer 20070915

Title: Suppressive effects of the anti-oxidant N-acetylcysteine on the anti-malarial activity of artesunate.

Journal: Parasitology international 20070901

Title: [Experimental study on artesunate inducing apoptosis of hypertrophic scar fibroblasts].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20070901

Title: Effect of the antimicrobial peptide gomesin against different life stages of Plasmodium spp.

Journal: Experimental parasitology 20070801

Title: Preparation of a novel monoclonal antibody against the antimalarial drugs, artemisinin and artesunate.

Journal: Planta medica 20070801

Title: [Immune response of dendritic cells capturing antigens from apoptotic U937 cells induced by artesunate].

Journal: Zhongguo shi yan xue ye xue za zhi 20070801

Title: Plasmodium yoelii: influence of antimalarial treatment on acquisition of immunity in BALB/c and DBA/2 mice.

Journal: Experimental parasitology 20070701

Title: The treatment of severe malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20070701

Title: The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs.

Journal: Annals of tropical medicine and parasitology 20070701

Title: Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites.

Journal: Molecular microbiology 20070701

Title: Artesunate-amodiaquine for the treatment of uncomplicated malaria.

Journal: Expert opinion on investigational drugs 20070701

Title: Amodiaquine in future combination treatment of malaria in Ghana.

Journal: Tropical doctor 20070701

Title: Rectal administration of artemisinin derivatives for the treatment of malaria.

Journal: JAMA 20070606

Title: Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.

Journal: Rheumatology (Oxford, England) 20070601

Title: Vivax malaria: preliminary observations following a shorter course of treatment with artesunate plus primaquine.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20070601

Title: Effect of artesunate plus sulfadoxine-pyrimethamine on haematological recovery and anaemia, in Kenyan children with uncomplicated, Plasmodium falciparum malaria.

Journal: Annals of tropical medicine and parasitology 20070601

Title: The risk of malarial infections and disease in Papua New Guinean children.

Journal: The American journal of tropical medicine and hygiene 20070601

Title: Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union.

Journal: Acta tropica 20070601

Title: [Apoptosis of HL-60 cells induced by artesunate in vitro].

Journal: Zhongguo shi yan xue ye xue za zhi 20070601

Title: Plasmodium vivax cerebral malaria.

Journal: Indian pediatrics 20070601

Title: Pattern of neurobehaviour in albino rats in the open field following oral artesunate administration.

Journal: African journal of medicine and medical sciences 20070601

Title: Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial.

Journal: JAMA 20070523

Title: Malaria-infected mice are cured by a single dose of novel artemisinin derivatives.

Journal: Journal of medicinal chemistry 20070517

Title: Lack of impact of artesunate on the disposition kinetics of sulfadoxine/pyrimethamine when the two drugs are concomitantly administered.

Journal: European journal of clinical pharmacology 20070501

Title: Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070415

Title: Artesunate, artemether or quinine in severe Plasmodium falciparum malaria?

Journal: Expert review of anti-infective therapy 20070401

Title: Caregivers' acceptance of using artesunate suppositories for treating childhood malaria in Papua New Guinea.

Journal: The American journal of tropical medicine and hygiene 20070401

Title: Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border.

Journal: The American journal of tropical medicine and hygiene 20070401

Title: [ASAQ, a breakthrough in the fight against malaria].

Journal: Medecine tropicale : revue du Corps de sante colonial 20070401

Title: Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315

Title: UK recommendations for severe malaria are worrying.

Journal: BMJ (Clinical research ed.) 20070310

Title: Cerebral malaria in spite of peripheral parasite clearance in a patient treated with atovaquone/proguanil.

Journal: Parasitology research 20070301

Title: Reactive desorption electrospray ionization linear ion trap mass spectrometry of latest-generation counterfeit antimalarials via noncovalent complex formation.

Journal: Analytical chemistry 20070301

Title: In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe.

Journal: Tropical medicine & international health : TM & IH 20070301

Title: Thiamin deficiency and uncomplicated falciparum malaria in Laos.

Journal: Tropical medicine & international health : TM & IH 20070301

Title: The comparative efficacies of malartin, with and without amodiaquine, in the treatment of Plasmodium falciparum malaria in the Buea district of Cameroon.

Journal: Annals of tropical medicine and parasitology 20070301

Title: Counterfeit artemisinin derivatives and Africa: update from authors.

Journal: PLoS medicine 20070301

Title: Comparative study of the effectiveness and pharmacokinetics of two rectal artesunate/oral mefloquine combination regimens for the treatment of uncomplicated childhood falciparum malaria.

Journal: Annals of tropical paediatrics 20070301

Title: Stability of artesunate in pharmaceutical solvents.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: New adamantane-based spiro 1,2,4-trioxanes orally effective against rodent and simian malaria.

Journal: Journal of medicinal chemistry 20070208

Title: Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201

Title: Toxicity evaluation of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine 20070201

Title: Case 32-2006: a girl with fever after a visit to Africa.

Journal: The New England journal of medicine 20070201

Title: In vitro antimalarial drug susceptibility and pfcrt mutation among fresh Plasmodium falciparum isolates from the Lao PDR (Laos).

Journal: The American journal of tropical medicine and hygiene 20070201

Title: Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment.

Journal: Tropical medicine & international health : TM & IH 20070201

Title: A randomized open study to assess the efficacy and tolerability of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Cambodia.

Journal: Tropical medicine & international health : TM & IH 20070201

Title: Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality.

Journal: Journal of pharmaceutical and biomedical analysis 20070104

Title: Combined Fourier-transform infrared imaging and desorption electrospray-ionization linear ion-trap mass spectrometry for analysis of counterfeit antimalarial tablets.

Journal: Analytical and bioanalytical chemistry 20070101

Title: Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo.

Journal: Tropical medicine & international health : TM & IH 20070101

Title: Recognition, perceptions and treatment practices for severe malaria in rural Tanzania: implications for accessing rectal artesunate as a pre-referral.

Journal: PloS one 20070101

Title: Overestimating resistance in field testing of malaria parasites: simple methods for estimating high EC50 values using a Bayesian approach.

Journal: Malaria journal 20070101

Title: Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.

Journal: Annals of tropical medicine and parasitology 20070101

Title: Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia.

Journal: Malaria journal 20070101

Title: Artesunate--amodiaquine combination therapy for falciparum malaria in young Gabonese children.

Journal: Malaria journal 20070101

Title: Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant.

Journal: Malaria journal 20070101

Title: Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré.

Journal: Malaria journal 20070101

Title: Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar.

Journal: Malaria journal 20070101

Title: Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal.

Journal: Malaria journal 20070101

Title: Artesunate inhibits angiogenesis and downregulates vascular endothelial growth factor expression in chronic myeloid leukemia K562 cells.

Journal: Vascular pharmacology 20070101

Title: A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan.

Journal: Malaria journal 20070101

Title: Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction.

Journal: Malaria journal 20070101

Title: Treatment of experimental nephrotic syndrome with artesunate.

Journal: International journal of toxicology 20070101

Title: Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells.

Journal: PloS one 20070101

Title: Battling the malaria iceberg with chloroquine in India.

Journal: Malaria journal 20070101

Title: Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate.

Journal: PloS one 20070101

Title: Malaria pharmacovigilance in Africa: lessons from a pilot project in Mpumalanga Province, South Africa.

Journal: Drug safety 20070101

Title: Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate.

Journal: PloS one 20070101

Title: A randomised controlled trial to assess the efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated falciparum malaria in Peru.

Journal: PloS one 20070101

Title: A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women.

Journal: PloS one 20070101

Title: Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal.

Journal: Malaria journal 20070101

Title: A randomized open-label trial of artesunate- sulfadoxine-pyrimethamine with or without primaquine for elimination of sub-microscopic P. falciparum parasitaemia and gametocyte carriage in eastern Sudan.

Journal: PloS one 20070101

Title: Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa.

Journal: Malaria journal 20070101

Title: The pharmacokinetics of intravenous artesunate in adults with severe falciparum malaria.

Journal: European journal of clinical pharmacology 20061201

Title: Adaptive response to the antimalarial drug artesunate in yeast involves Pdr1p/Pdr3p-mediated transcriptional activation of the resistance determinants TPO1 and PDR5.

Journal: FEMS yeast research 20061201

Title: Efficacy of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia.

Journal: Tropical medicine & international health : TM & IH 20061201

Title: In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

Journal: Tropical medicine & international health : TM & IH 20061201

Title: [Extraction of artemisinin and synthesis of its derivates artesunate and artemether].

Journal: Medecine tropicale : revue du Corps de sante colonial 20061201

Title: Azithromycin combination therapy with artesunate or quinine for the treatment of uncomplicated Plasmodium falciparum malaria in adults: a randomized, phase 2 clinical trial in Thailand.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20061115

Title: Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: An open label randomized comparison of mefloquine-artesunate as separate tablets vs. a new co-formulated combination for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

Journal: Tropical medicine & international health : TM & IH 20061101

Title: Characterization of counterfeit artesunate antimalarial tablets from southeast Asia.

Journal: The American journal of tropical medicine and hygiene 20061101

Title: The evaluation of radiolabeled artesunate on tissue distribution in rats and protein binding in humans.

Journal: The American journal of tropical medicine and hygiene 20061101

Title: Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients.

Journal: PLoS medicine 20061101

Title: [A case of severe falciparum malaria successfully treated with intravenous artesunate and continuous hemodiafiltration].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20061101

Title: Effect of artesunate and artemether against Clonorchis sinensis and Opisthorchis viverrini in rodent models.

Journal: International journal of antimicrobial agents 20061001

Title: Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes.

Journal: Tropical medicine & international health : TM & IH 20061001

Title: A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20061001

Title: In vitro activity of artemisone compared with artesunate against Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene 20061001

Title: Artesunate-induced depletion of embryonic erythroblasts precedes embryolethality and teratogenicity in vivo.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20061001

Title: Potentiation of antimalarial drug action by chlorpheniramine against multidrug-resistant Plasmodium falciparum in vitro.

Journal: Parasitology international 20060901

Title: Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectiveness.

Journal: Tropical medicine & international health : TM & IH 20060901

Title: Surveillance of the efficacy of artesunate and mefloquine combination for the treatment of uncomplicated falciparum malaria in Cambodia.

Journal: Tropical medicine & international health : TM & IH 20060901

Title: Submicroscopic Plasmodium falciparum infections before and after sulfadoxine-pyrimethamine and artesunate association treatment in Dienga, Southeastern Gabon.

Journal: Clinical medicine & research 20060901

Title: Artesunate and a major metabolite, dihydroartemisinin, diminish mitogen-induced lymphocyte proliferation and activation.

Journal: The Southeast Asian journal of tropical medicine and public health 20060901

Title: Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites?

Journal: Journal of tropical pediatrics 20060801

Title: An open, randomized comparison of artesunate plus mefloquine vs. dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Lao People's Democratic Republic (Laos).

Journal: Tropical medicine & international health : TM & IH 20060801

Title: Artesunate plus sulfadoxine-pyrimethamine in the treatment of uncomplicated Plasmodium falciparum malaria during pregnancy in eastern Sudan.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060701

Title: Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.

Journal: Experimental parasitology 20060701

Title: We still need artesunate monotherapy.

Journal: BMJ (Clinical research ed.) 20060701

Title: Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone.

Journal: Tropical medicine & international health : TM & IH 20060701

Title: High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola.

Journal: The American journal of tropical medicine and hygiene 20060701

Title: Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry.

Journal: ChemMedChem 20060701

Title: Artemisinin combination therapies.

Journal: Lancet (London, England) 20060624

Title: Efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison.

Journal: Lancet (London, England) 20060624

Title: Artesunate and artemether are effective fasciolicides in the rat model and in vitro.

Journal: The Journal of antimicrobial chemotherapy 20060601

Title: Deployment of early diagnosis and mefloquine-artesunate treatment of falciparum malaria in Thailand: the Tak Malaria Initiative.

Journal: PLoS medicine 20060601

Title: Resisting resistance: dealing with the irrepressible problem of malaria.

Journal: British journal of clinical pharmacology 20060601

Title: Manslaughter by fake artesunate in Asia--will Africa be next?

Journal: PLoS medicine 20060601

Title: Malaria: severe, life threatening.

Journal: Clinical evidence 20060601

Title: Ex vivo perfusion of human spleens maintains clearing and processing functions.

Journal: Blood 20060501

Title: Schistosoma mekongi: the in vitro effect of praziquantel and artesunate on the adult fluke.

Journal: Experimental parasitology 20060501

Title: Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria.

Journal: European journal of clinical pharmacology 20060501

Title: [Relapse of Plasmodium falciparum malaria in a patient treated with artesunate].

Journal: Medecine et maladies infectieuses 20060501

Title: Malaria. 'One step forward, two steps back'.

Journal: East African medical journal 20060501

Title: Efficacy and safety of an artesunate/mefloquine combination, (artequin) in the treatment of uncomplicated P. falciparum malaria in Kenya.

Journal: East African medical journal 20060501

Title: (Sub)microscopic Plasmodium falciparum gametocytaemia in Kenyan children after treatment with sulphadoxine-pyrimethamine monotherapy or in combination with artesunate.

Journal: International journal for parasitology 20060401

Title: Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?

Journal: Tropical medicine & international health : TM & IH 20060401

Title: [Effects of artesunate on CD14 and toll-like receptor 4 in peritoneal macrophages of mice with heat stroke endotoxemia].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060401

Title: Evaluation of the anthelmintic effects of artesunate against experimental Schistosoma mansoni infection in mice using different treatment protocols.

Journal: Parasitology international 20060301

Title: Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial.

Journal: Lancet (London, England) 20060225

Title: A randomized trial comparing the efficacy of four treatment regimens for uncomplicated falciparum malaria in Assam state, India.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060201

Title: The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.

Journal: Antiviral research 20060201

Title: Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase), tctp, mdr1, and cg10.

Journal: Antimicrobial agents and chemotherapy 20060201

Title: In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

Journal: Tropical medicine & international health : TM & IH 20060201

Title: Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20060125

Title: Artesunate versus quinine for severe falciparum malaria.

Journal: Lancet (London, England) 20060114

Title: Artesunate versus quinine for severe falciparum malaria.

Journal: Lancet (London, England) 20060114

Title: Improving the availability of artesunate for treatment of severe malaria.

Journal: The Medical journal of Australia 20060102

Title: The efficacies of artesunate-sulfadoxine-pyrimethamine and artemether-lumefantrine in the treatment of uncomplicated, Plasmodium falciparum malaria, in an area of low transmission in central Sudan.

Journal: Annals of tropical medicine and parasitology 20060101

Title: Successful treatment of imported cerebral malaria with artesunate-mefloquine combination therapy.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20060101

Title: Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial.

Journal: Malaria journal 20060101

Title: Pharmacokinetics/Pharmacodynamics findings after repeated administration of ARTESUNATE thermostable suppositories (RECTOCAPS) in Vietnamese patients with uncomplicated malaria.

Journal: European journal of drug metabolism and pharmacokinetics 20060101

Title: Role of traditional healers in the management of severe malaria among children below five years of age: the case of Kilosa and Handeni Districts, Tanzania.

Journal: Malaria journal 20060101

Title: From chloroquine to artemisinin-based combination therapy: the Sudanese experience.

Journal: Malaria journal 20060101

Title: A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan.

Journal: Annals of clinical microbiology and antimicrobials 20060101

Title: Design of a new line in treatment of experimental rheumatoid arthritis by artesunate.

Journal: Immunopharmacology and immunotoxicology 20060101

Title: Malaria treatment failures after artemisinin-based therapy in three expatriates: could improved manufacturer information help to decrease the risk of treatment failure?

Journal: Malaria journal 20060101

Title: Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo.

Journal: Malaria journal 20060101

Title: Fatty food does not alter blood mefloquine concentrations in the treatment of falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051201

Title: Misattribution of central nervous system dysfunction to artesunate.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051201

Title: Artesunate in the treatment of metastatic uveal melanoma--first experiences.

Journal: Oncology reports 20051201

Title: Short communication: high prevalence of the cytochrome P450 2C8*2 mutation in Northern Ghana.

Journal: Tropical medicine & international health : TM & IH 20051201

Title: Intravenous artesunate recommended for patients with severe malaria: position statement from TropNetEurop.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20051124

Title: Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an 'in vitro' replicative system.

Journal: Antiviral research 20051101

Title: Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.

Journal: Tropical medicine & international health : TM & IH 20051101

Title: Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria.

Journal: The Cochrane database of systematic reviews 20051019

Title: Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015

Title: Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051001

Title: 5-day nonobserved artesunate monotherapy for treating uncomplicated Falciparum malaria in young Gabonese children.

Journal: The American journal of tropical medicine and hygiene 20051001

Title: Effects of praziquantel and artesunate on the tegument of adult Schistosoma mekongi harboured in mice.

Journal: Parasitology international 20050901

Title: Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana.

Journal: Acta tropica 20050901

Title: A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy.

Journal: The Journal of infectious diseases 20050901

Title: Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal.

Journal: Tropical medicine & international health : TM & IH 20050901

Title: Association of failures of seven-day courses of artesunate in a non-immune population in Bangui, Central African Republic with decreased sensitivity of Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene 20050901

Title: An open randomized clinical trial of Artekin vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20050901

Title: Comparative studies on the pathological findings and mortality in Schistosoma mansoni infected mice after treatment with artesunate and the current antischistosomal drugs.

Journal: The Southeast Asian journal of tropical medicine and public health 20050901

Title: A randomized, controlled study of a simple, once-daily regimen of dihydroartemisinin-piperaquine for the treatment of uncomplicated, multidrug-resistant falciparum malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050815

Title: Short report: no evidence of cardiotoxicity of atovaquone-proguanil alone or in combination with artesunate.

Journal: The American journal of tropical medicine and hygiene 20050801

Title: Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial.

Journal: Lancet (London, England) 20050801

Title: Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.

Journal: Journal of medicinal chemistry 20050728

Title: Synthesis and immunosuppressive activity of new artemisinin derivatives. 1. [12(beta or alpha)-Dihydroartemisininoxy]phen(ox)yl aliphatic acids and esters.

Journal: Journal of medicinal chemistry 20050714

Title: Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701

Title: Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701

Title: A comparison of the efficacy of artesunate plus sulfadoxine-pyrimethamine with that of sulfadoxine-pyrimethamine alone, in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.

Journal: Annals of tropical medicine and parasitology 20050701

Title: The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.

Journal: Annals of tropical medicine and parasitology 20050701

Title: Artesunate-clindamycin versus quinine-clindamycin in the treatment of Plasmodium falciparum malaria: a randomized controlled trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050615

Title: New malaria combination cheaper and easier to take.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050607

Title: Neurotoxicity due to antimalarial therapy associated with misdiagnosis of malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050601

Title: A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malaria.

Journal: Tropical medicine & international health : TM & IH 20050601

Title: Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan.

Journal: Tropical medicine & international health : TM & IH 20050601

Title: Malaria: uncomplicated, caused by Plasmodium falciparum.

Journal: Clinical evidence 20050601

Title: WHO combats counterfeit malaria drugs in Asia.

Journal: BMJ (Clinical research ed.) 20050507

Title: Curdlan sulphate in human severe/cerebral Plasmodium falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050501

Title: New combination drug to treat malaria.

Journal: The Lancet. Infectious diseases 20050501

Title: Efficacy and tolerability of artesunate plus sulfadoxine-pyrimethamine and sulfadoxine-pyrimethamine alone for the treatment of uncomplicated Plasmodium falciparum malaria in Peru.

Journal: The American journal of tropical medicine and hygiene 20050501

Title: An open, randomized trial of three-day treatment with artesunate combined with a standard dose of mefloquine divided over either two or three days, for acute, uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20050501

Title: Life-saving rectal artesunate for complicated malaria in children.

Journal: The Southeast Asian journal of tropical medicine and public health 20050501

Title: Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial.

Journal: Lancet (London, England) 20050401

Title: Efficacies of mefloquine alone and of artesunate followed by mefloquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.

Journal: Annals of tropical medicine and parasitology 20050301

Title: Development and validation of a high-performance liquid chromatography-mass spectroscopy assay for determination of artesunate and dihydroartemisinin in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Artesunate-dapsone-proguanil treatment of falciparum malaria: genotypic determinants of therapeutic response.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20050201

Title: Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia.

Journal: Tropical medicine & international health : TM & IH 20050201

Title: The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: a model of the selection of resistance by antifolate drugs and their combinations.

Journal: The American journal of tropical medicine and hygiene 20050201

Title: In vitro monitoring of Plasmodium falciparum susceptibility to artesunate, mefloquine, quinine and chloroquine in Cambodia: 2001-2002.

Journal: Acta tropica 20050101

Title: Efficacy of two artemisinin combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile, Sudan.

Journal: Malaria journal 20050101

Title: A qualitative study to identify community structures for management of severe malaria: a basis for introducing rectal artesunate in the under five years children in Nakonde District of Zambia.

Journal: BMC public health 20050101

Title: Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate.

Journal: In vivo (Athens, Greece) 20050101

Title: Investigation of bioavailability, pharmacokinetics and safety of new pediatric formulations of artesunate and mefloquine.

Journal: The Southeast Asian journal of tropical medicine and public health 20050101

Title: Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins.

Journal: Acta tropica 20050101

Title: Artesunate reduces proliferation, interferes DNA replication and cell cycle and enhances apoptosis in vascular smooth muscle cells.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

Title: Toxicokinetics and hydrolysis of artelinate and artesunate in malaria-infected rats.

Journal: International journal of toxicology 20050101

Title: Risk assessment and therapeutic indices of artesunate and artelinate in Plasmodium berghei-infected and uninfected rats.

Journal: International journal of toxicology 20050101

Title: Artesunate plus sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum malaria in Sudan.

Journal: Malaria journal 20050101

Title: A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand.

Journal: Malaria journal 20050101

Title: Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate.

Journal: Biochemical pharmacology 20041215

Title: Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials.

Journal: Tropical medicine & international health : TM & IH 20041201

Title: Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20041201

Title: A female patient with malarial nephropathy.

Journal: Clinical and experimental nephrology 20041201

Title: Adherence to antimalarial combination therapy with sulfadoxine-pyrimethamine and artesunate in rural Tanzania.

Journal: The American journal of tropical medicine and hygiene 20041201

Title: [Protection of artesunate on activation and injury of vascular endothelial cells induced by lipopolysaccharide].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20041201

Title: The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate.

Journal: Annals of tropical medicine and parasitology 20041201

Title: Randomized, controlled dose-optimization studies of dihydroartemisinin-piperaquine for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

Journal: The Journal of infectious diseases 20041115

Title: Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic.

Journal: Tropical medicine & international health : TM & IH 20041101

Title: Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.

Journal: Tropical medicine & international health : TM & IH 20041101

Title: Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial.

Journal: Lancet (London, England) 20041101

Title: Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

Title: Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria.

Journal: Tropical medicine & international health : TM & IH 20041001

Title: Declining mefloquine sensitivity of Plasmodium falciparum along the Thai-Myanmar border.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Therapeutic efficacy of artesunate in Plasmodium vivax malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: The pharmacokinetics of oral dihydroartemisinin and artesunate in healthy Thai volunteers.

Journal: The Southeast Asian journal of tropical medicine and public health 20040901

Title: Artesunate reduces chicken chorioallantoic membrane neovascularisation and exhibits antiangiogenic and apoptotic activity on human microvascular dermal endothelial cell.

Journal: Cancer letters 20040810

Title: Artesunate with mefloquine at various intervals for non-severe Plasmodium falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20040801

Title: Efficacy of artesunate in the treatment of urinary schistosomiasis, in an endemic community in Nigeria.

Journal: Annals of tropical medicine and parasitology 20040701

Title: Pharmacokinetics of artesunate following oral and rectal administration in healthy Sudanese volunteers.

Journal: Tropical doctor 20040701

Title: Apoptosis of human umbilical vein endothelial cells induced by artesunate.

Journal: Vascular pharmacology 20040701

Title: [Efficacy of therapeutic combinations with artemisinin derivatives in the treatment of non complicated malaria in Burundi].

Journal: Tropical medicine & international health : TM & IH 20040601

Title: The in-vitro antimalarial activity of ferrochloroquine, measured against Cambodian isolates of Plasmodium falciparum.

Journal: Annals of tropical medicine and parasitology 20040601

Title: [Combined antimalarial therapy using artemisinin].

Journal: Parassitologia 20040601

Title: Efficacy of rectal artesunate compared with parenteral quinine in initial treatment of moderately severe malaria in African children and adults: a randomised study.

Journal: Lancet (London, England) 20040515

Title: Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.

Journal: Journal of medicinal chemistry 20040506

Title: Inhibitory effects of artesunate on angiogenesis and on expressions of vascular endothelial growth factor and VEGF receptor KDR/flk-1.

Journal: Pharmacology 20040501

Title: Combination treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774.

Journal: Biochemical pharmacology 20040501

Title: Efficacy of sulfadoxin pyrimethamine for uncomplicated Plasmodium falciparum malaria in a small sample of Sudanese children.

Journal: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20040501

Title: Ghana battles drug-resistant malaria with artesunate.

Journal: Lancet (London, England) 20040424

Title: A randomized trial of amodiaquine and artesunate alone and in combination for the treatment of uncomplicated falciparum malaria in children from Burkina Faso.

Journal: Tropical medicine & international health : TM & IH 20040401

Title: Randomized control trial of quinine and artesunate in complicated malaria.

Journal: Indian journal of pediatrics 20040401

Title: Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin.

Journal: Journal of medicinal chemistry 20040311

Title: Optimising operational use of artesunate-mefloquine: a randomised comparison of four treatment regimens.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20040301

Title: Artesunate combinations for malaria.

Journal: Lancet (London, England) 20040227

Title: [Prophylactic effect of artesunate against experimental infection of Schistosoma mansoni].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20040227

Title: Efficacy of mefloquine and mefloquine-artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon region of Bolivia.

Journal: Tropical medicine & international health : TM & IH 20040201

Title: Artesunate combinations for treatment of malaria: meta-analysis.

Journal: Lancet (London, England) 20040103

Title: Addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children causes a significant but short-lived reduction in infectiousness for mosquitoes.

Journal: Tropical medicine & international health : TM & IH 20040101

Title: Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, Zambia.

Journal: Tropical medicine & international health : TM & IH 20040101

Title: [Inhibitory effects of artesunate on angiogenesis].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040101

Title: Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.

Journal: Lancet (London, England) 20040101

Title: In vitro sensitivity of Plasmodium falciparum to lumefantrine in north-western Thailand.

Journal: Wiener klinische Wochenschrift 20040101

Title: Plasma concentrations of tafenoquine, a new long-acting antimalarial agent, in thai soldiers receiving monthly prophylaxis.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031215

Title: Preparation of 10-trifluoromethyl artemether and artesunate. Influence of hexafluoropropan-2-ol on substitution reaction.

Journal: The Journal of organic chemistry 20031212

Title: Treatment of uncomplicated falciparum malaria in southern Vietnam: can chloroquine or sulfadoxine-pyrimethamine be reintroduced in combination with artesunate?

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20031201

Title: Randomised efficacy and safety study of two 3-day artesunate rectal capsule/mefloquine regimens versus artesunate alone for uncomplicated malaria in Ecuadorian children.

Journal: Acta tropica 20031201

Title: New antimalarial drugs.

Journal: Angewandte Chemie (International ed. in English) 20031110

Title: Antimalarial compounds: from bench to bedside.

Journal: The Journal of experimental biology 20031101

Title: Prevention of increasing rates of treatment failure by combining sulfadoxine-pyrimethamine with artesunate or amodiaquine for the sequential treatment of malaria.

Journal: The Journal of infectious diseases 20031015

Title: The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria.

Journal: European journal of clinical pharmacology 20031001

Title: Role of antioxidant genes for the activity of artesunate against tumor cells.

Journal: International journal of oncology 20031001

Title: Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro.

Journal: Pharmacological research 20030901

Title: Atovaquone-proguanil for recrudescent Plasmodium falciparum in Vietnam.

Journal: Annals of tropical medicine and parasitology 20030901

Title: Red cell exchange using cell separator (therapeutic erythrocytapheresis) in two children with acute severe malaria.

Journal: The Journal of the Association of Physicians of India 20030901

Title: Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: Six-years monitoring the efficacy of the combination of artesunate and mefloquine for the treatment of uncomplicated falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: [A randomized comparative study of naphtoquine, mefloquine and artsunate in the treatment of falciparum malaria].

Journal: Zhonghua yi xue za zhi 20030825

Title: Sleuthful pharmacology.

Journal: Molecular pharmacology 20030801

Title: Molecular modes of action of artesunate in tumor cell lines.

Journal: Molecular pharmacology 20030801

Title: Comparison of bioassay and high performance liquid chromatographic assay of artesunate and dihydroartemisinin in plasma.

Journal: Acta tropica 20030801

Title: Estimating the needs for artesunate-based combination therapy for malaria case-management in Africa.

Journal: Trends in parasitology 20030801

Title: [Systematic review of benefits and harms of artemisinin-type compounds for preventing schistosomiasis].

Journal: Zhonghua yi xue za zhi 20030725

Title: Counterfeit artesunate antimalarials in southeast Asia.

Journal: Lancet (London, England) 20030712

Title: Randomized comparison of artesunate and quinine in the treatment of severe falciparum malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030701

Title: Clinical trial of oral artesunate with or without high-dose primaquine for the treatment of vivax malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20030701

Title: The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.

Journal: The American journal of tropical medicine and hygiene 20030701

Title: Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate.

Journal: The American journal of tropical medicine and hygiene 20030601

Title: Efficacy of mefloquine and a mefloquine-artesunate combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon Basin of Peru.

Journal: The American journal of tropical medicine and hygiene 20030501

Title: The efficacy of combined mefloquine-artesunate versus mefloquine-primaquine on subsequent development of Plasmodium falciparum gametocytemia.

Journal: The American journal of tropical medicine and hygiene 20030501

Title: Efficacy comparison of intravenous artelinate and artesunate in Plasmodium berghei-infected Sprague-Dawley rats.

Journal: Parasitology 20030401

Title: Physical and chemical evaluation of liposomes, containing artesunate.

Journal: Journal of pharmaceutical and biomedical analysis 20030326

Title: Oral artesunate prevents Plasmodium berghei Anka infection in mice.

Journal: Parasitology international 20030301

Title: Safety and therapeutic efficacy of artesunate suppositories for treatment of malaria in children in Papua New Guinea.

Journal: The Pediatric infectious disease journal 20030301

Title: N-acetylcysteine in severe falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030301

Title: Clinical experience with intravenous quinine, intramuscular artemether and intravenous artesunate for the treatment of severe malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030301

Title: [Lipid-peroxidantion damage of embryo and placenta induced by artesunate in rats].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030201

Title: Distinguishing recrudescence from reinfection in a longitudinal antimalarial drug efficacy study: comparison of results based on genotyping of msp-1, msp-2, and glurp.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Drug-resistant malaria in Bangladesh: an in vitro assessment.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Recrudescence in artesunate-treated patients with falciparum malaria is dependent on parasite burden not on parasite factors.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Descriptive study on the efficacy and safety of artesunate suppository in combination with other antimalarials in the treatment of severe malaria in Sudan.

Journal: The American journal of tropical medicine and hygiene 20030201

Title: Lack of prediction of mefloquine and mefloquine-artesunate treatment outcome by mutations in the Plasmodium falciparum multidrug resistance 1 (pfmdr1) gene for P. falciparum malaria in Peru.

Journal: The American journal of tropical medicine and hygiene 20030101

Title: [Short course schemes for vivax malaria treatment].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20030101

Title: [Hypertriglyceridemia related to falciparum malaria: the role played by glycerol].

Journal: Annales de biologie clinique 20030101

Title: [Drug resistant tropical malaria in the Republic of Guinea (West Africa)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20030101

Title: The effect of mass administration of sulfadoxine-pyrimethamine combined with artesunate on malaria incidence: a double-blind, community-randomized, placebo-controlled trial in The Gambia.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Changes in susceptibility of Plasmodium falciparum to artesunate in vitro in Yunnan Province, China.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: [Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

Title: Drug resistant falciparum malaria and the use of artesunate-based combinations: focus on clinical trials sponsored by TDR.

Journal: Journal of vector borne diseases 20030101

Title: Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Efficacy of artesunate plus chloroquine for the treatment of uncomplicated malaria in children in Burkina Faso: a double-blind, randomized, controlled trial.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: No benefits from combining chloroquine with artesunate for three days for treatment of Plasmodium falciparum in Guinea-Bissau.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Artesunate plus sulfadoxine-pyrimethamine for uncomplicated malaria in Kenyan children: a randomized, double-blind, placebo-controlled trial.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Artesunate-atovaquone-proguanil rescue treatment of multidrug-resistant Plasmodium falciparum malaria in pregnancy: a preliminary report.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Efficacy of artesunate plus chloroquine for uncomplicated malaria in children in Sao Tome and Principe: a double-blind, randomized, controlled trial.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Treatment of uncomplicated multidrug-resistant falciparum malaria with artesunate-atovaquone-proguanil.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021215

Title: Modulation of multidrug resistance by artemisinin, artesunate and dihydroartemisinin in K562/adr and GLC4/adr resistant cell lines.

Journal: Biological & pharmaceutical bulletin 20021201

Title: Sulfadoxine/pyrimethamine alone or with amodiaquine or artesunate for treatment of uncomplicated malaria: a longitudinal randomised trial.

Journal: Lancet (London, England) 20021201

Title: Evidence for the efficacy of artesunate in asymptomatic Plasmodium malariae infections.

Journal: The Journal of antimicrobial chemotherapy 20021101

Title: Artesunate and mefloquine given simultaneously for three days via a prepacked blister is equally effective and tolerated as a standard sequential treatment of uncomplicated acute Plasmodium falciparum malaria: randomized, double-blind study in Thailand.

Journal: The American journal of tropical medicine and hygiene 20021101

Title: Diuretic effect of sodium artesunate in patients with malaria.

Journal: The American journal of tropical medicine and hygiene 20021101

Title: Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid.

Journal: Journal of medicinal chemistry 20021024

Title: [A case of falciparum malaria successfully treated with intravenous artesunate].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20021001

Title: Use of nested PCR for differential diagnosis of falciparum malaria reinfection and relapse in drug-resistant patients.

Journal: Bulletin of experimental biology and medicine 20021001

Title: Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020901

Title: A safety and efficacy trial of artesunate, sulphadoxine-pyrimethamine and primaquine in P falciparum malaria.

Journal: The Ceylon medical journal 20020901

Title: An open randomized clinical trial of Artecom vs artesunate-mefloquine in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20020901

Title: [A study on the percutaneous penetration of artesunate from various reservoir vehicles].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20020901

Title: mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether.

Journal: Biochemical pharmacology 20020815

Title: [Severe falciparum malaria with prolonged hemolytic anemia after successful treatment with intravenous artesunate].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20020801

Title: Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum must be delayed in Africa.

Journal: Trends in parasitology 20020701

Title: Resistant malaria in a neonate.

Journal: Indian pediatrics 20020601

Title: [Artemisinine and artesunate in the treatment of malaria in Vietnam (1984-1999)].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20020601

Title: [The anticancer effect of artesunate and its mechanism].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020601

Title: Central role of the spleen in malaria parasite clearance.

Journal: The Journal of infectious diseases 20020515

Title: Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised, multicentre trial.

Journal: Lancet (London, England) 20020420

Title: Efficacy of artesunate and praziquantel in Schistosoma haematobium infected schoolchildren.

Journal: Acta tropica 20020401

Title: Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.

Journal: Journal of molecular medicine (Berlin, Germany) 20020401

Title: Impact of large-scale rectal artesunate deployment in the emergency management of malaria.

Journal: Releve epidemiologique hebdomadaire 20020322

Title: Relative bioavailability of artesunate and dihydroartemisinin: investigations in the isolated perfused rat liver and in healthy Caucasian volunteers.

Journal: The American journal of tropical medicine and hygiene 20020201

Title: Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine.

Journal: Parasitology 20020101

Title: The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria.

Journal: British journal of clinical pharmacology 20020101

Title: Glucose and lactate turnover in adults with falciparum malaria: effect of complications and antimalarial therapy.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: [In vitro response of Plasmodium falciparum FCC1/HN to artesunate, pyronaridine and other antimalarials].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20020101

Title: A randomized, double-blind study on the efficacy and safety of a practical three-day regimen with artesunate and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in Africa.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: Plasmodium falciparum: effect of anti-malarial drugs on the production and secretion characteristics of histidine-rich protein II.

Journal: Experimental parasitology 20020101

Title: In vitro effect of artesunate against Acanthamoeba spp.

Journal: The Southeast Asian journal of tropical medicine and public health 20020101

Title: Treatment of falciparum malaria in Vietnamese children: the need for combination therapy and optimized dosage regimens.

Journal: Annals of tropical paediatrics 20011201

Title: A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria.

Journal: British journal of clinical pharmacology 20011201

Title: Population pharmacokinetics of the new antimalarial agent tafenoquine in Thai soldiers.

Journal: British journal of clinical pharmacology 20011201

Title: Authentication of artemether, artesunate and dihydroartemisinin antimalarial tablets using a simple colorimetric method.

Journal: Tropical medicine & international health : TM & IH 20011201

Title: Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malaria.

Journal: The American journal of tropical medicine and hygiene 20011201

Title: Artesunate and praziquantel for the treatment of Schistosoma haematobium infections: a double-blind, randomized, placebo-controlled study.

Journal: The Journal of infectious diseases 20011115

Title: Histopathological changes of Macaca mulatta infected with Plasmodium knowlesi.

Journal: Chinese medical journal 20011001

Title: Multiple dose study of interactions between artesunate and artemisinin in healthy volunteers.

Journal: British journal of clinical pharmacology 20011001

Title: Therapy of uncomplicated falciparum malaria: a randomized trial comparing artesunate plus sulfadoxine-pyrimethamine versus sulfadoxine-pyrimethamine alone in Irian Jaya, Indonesia.

Journal: The American journal of tropical medicine and hygiene 20011001

Title: Malaria as a cause of multi organ failure.

Journal: The Journal of the Association of Physicians of India 20011001

Title: [Experimental studies of antitumor effect of artesunate on liver cancer].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20011001

Title: [A case of falciparum malaria successfully treated with intravenous artesunate].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010901

Title: Randomized trial of artesunate and mefloquine in comparison with quinine sulfate to treat P. falciparum malaria pregnant women.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010901

Title: Potent antimalarial activities of polyether antibiotic, X-206.

Journal: The Journal of antibiotics 20010801

Title: Bogus antimalarials: a forgotten tale.

Journal: Trends in parasitology 20010801

Title: Apparent drug failure following artesunate treatment of Plasmodium falciparum malaria in Freetown, Sierra Leone: four case reports.

Journal: Annals of tropical medicine and parasitology 20010701

Title: Fake artesunate in southeast Asia.

Journal: Lancet (London, England) 20010616

Title: Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children.

Journal: Journal of tropical pediatrics 20010601

Title: Artesunate reduces but does not prevent posttreatment transmission of Plasmodium falciparum to Anopheles gambiae.

Journal: The Journal of infectious diseases 20010415

Title: The anti-malarial artesunate is also active against cancer.

Journal: International journal of oncology 20010401

Title: [Effects of artesunate on progestrone estrogen content and decidua in rats].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010401

Title: Fake antimalaria drugs in Cambodia.

Journal: Lancet (London, England) 20010317

Title: Effects of sodium artesunate, a new antimalarial drug, on renal function.

Journal: Kidney international 20010301

Title: Drug resistant malaria on the Thai-Myanmar and Thai-Cambodian borders.

Journal: The Southeast Asian journal of tropical medicine and public health 20010301

Title: [In vitro study of the anti-pneumocystis carinii effect of arteminsin derivatives].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20010301

Title: Parasitaemia and gametocytaemia after treatment with chloroquine, pyrimethamine/sulfadoxine, and pyrimethamine/sulfadoxine combined with artesunate in young Gambians with uncomplicated malaria.

Journal: Tropical medicine & international health : TM & IH 20010201

Title: Severe allergic reactions to oral artesunate: a report of two cases.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Resistance of Plasmodium falciparum to antimalarial drugs in a highly endemic area of southern Viet Nam: a study in vivo and in vitro.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: The safety of the combination artesunate and pyrimethamine-sulfadoxine given during pregnancy.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Acute asymptomatic hepatitis in a healthy normal volunteer exposed to 2 oral doses of amodiaquine and artesunate.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: A comparison of artesunate alone with combined artesunate and quinine in the parenteral treatment of acute falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Randomized comparison of quinine-clindamycin versus artesunate in the treatment of falciparum malaria in pregnancy.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: Pharmacokinetics of artesunate after single oral administration to rats.

Journal: BMC pharmacology 20010101

Title: [Studies on the preventive effect of artesunate against Schistosoma japonicum infection].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20010101

Title: The effect of artesunate combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 19990101

Title: Ilamathi M, et al. Artesunate as an Anti-Cancer Agent Targets Stat-3 and Favorably Suppresses Hepatocellular Carcinoma. Curr Top Med Chem. 2016;16(22):2453-63.

Title: Lisewski AM, et al. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 2014 Aug 14;158(4):916-928.

Title: Wang B, et al. Artesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51. Cancer Biol Ther. 2015;16(10):1548-56.

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Tags:88495-63-0 Molecular Formula|88495-63-0 MDL|88495-63-0 SMILES|88495-63-0 Butanedioic acid,mono[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester