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80621-81-4,MFCD00864973
Catalog No.:AA00ILK0

80621-81-4 | Rifaximin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
≥98%
in stock  
$63.00   $44.00
- +
250mg
≥97%
in stock  
$115.00   $80.00
- +
500mg
≥98%
in stock  
$116.00   $81.00
- +
1g
>97.0%(HPLC)(N)
in stock  
$146.00   $102.00
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5g
>97.0%(HPLC)(N)
in stock  
$527.00   $369.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ILK0
Chemical Name:
Rifaximin
CAS Number:
80621-81-4
Molecular Formula:
C43H51N3O11
Molecular Weight:
785.8785
MDL Number:
MFCD00864973
SMILES:
CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C2=O)c2c(c(c3C)O)c(O)c(c3c2nc2n3ccc(c2)C)NC(=O)/C(=C\C=C\[C@@H]([C@@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]1C)OC(=O)C)C)O)C)O)C)/C
Properties
Computed Properties
 
Complexity:
1590  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
57  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
6.9  

Upstream Synthesis Route

[1]JournalofMedicinalChemistry,1985,vol.28,#7,p.960-963

[1]JournalofMedicinalChemistry,1985,vol.28,#7,p.960-963

Downstream Synthesis Route
C43H50N3O11(1+)*Br(1-) 
  80621-81-4 

[1]JournalofMedicinalChemistry,1985,vol.28,p.960-963

[1]JournalofMedicinalChemistry,1985,vol.28,p.960-963

[1]JournalofMedicinalChemistry,1985,vol.28,p.960-963

Literature

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Journal: Journal of clinical gastroenterology 20120901

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Title: [Proton-pump inhibitor therapy and small bowel bacterial contamination].

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Title: Fidaxomicin inhibits spore production in Clostridium difficile.

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Title: Rifaximin improves systemic hemodynamics and renal function in patients with alcohol-related cirrhosis and ascites.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20120701

Title: High-resolution melting analysis of the single nucleotide polymorphism hot-spot region in the rpoB gene as an indicator of reduced susceptibility to rifaximin in Clostridium difficile.

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Journal: Acta gastroenterologica Latinoamericana 20120601

Title: Rifaximin, but not growth factor 1, reduces brain edema in cirrhotic rats.

Journal: World journal of gastroenterology 20120507

Title: Hepatic encephalopathy.

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Title: Structural elucation of a novel impurity in rifaximin.

Journal: Die Pharmazie 20120501

Title: Diagnosis and treatment of minimal hepatic encephalopathy to prevent motor vehicle accidents: a cost-effectiveness analysis.

Journal: Hepatology (Baltimore, Md.) 20120401

Title: Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice.

Journal: Journal of hepatology 20120401

Title: Probable rifaximin-induced neutropenia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120401

Title: Evaluation of harm in the pharmacotherapy of irritable bowel syndrome.

Journal: The American journal of medicine 20120401

Title: [Hepatic encephalopathy and liver transplantation].

Journal: Magyar sebeszet 20120401

Title: Impurity profile of rifaximin produced in China.

Journal: Die Pharmazie 20120401

Title: Recurrent refractory Clostridium difficile colitis treated successfully with rifaximin and tigecycline: a case report and review of the literature.

Journal: Scandinavian journal of infectious diseases 20120301

Title: Rifaximin improves thrombocytopenia in patients with alcoholic cirrhosis in association with reduction of endotoxaemia.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20120301

Title: Rifaximin-extended intestinal release induces remission in patients with moderately active Crohn's disease.

Journal: Gastroenterology 20120301

Title: The diagnosis and treatment of minimal hepatic encephalopathy.

Journal: Deutsches Arzteblatt international 20120301

Title: Rifaximin vs. conventional oral therapy for hepatic encephalopathy: a meta-analysis.

Journal: World journal of gastroenterology 20120227

Title: Durability of rifaximin response in hepatic encephalopathy.

Journal: Journal of clinical gastroenterology 20120201

Title: Rifaximin for the treatment of irritable bowel syndrome.

Journal: Expert opinion on pharmacotherapy 20120201

Title: Management of overt hepatic encephalopathy.

Journal: Clinics in liver disease 20120201

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Journal: Journal of medicinal chemistry 20120112

Title: Linkage of gut microbiome with cognition in hepatic encephalopathy.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120101

Title: The efficacy and safety of rifaximin for the irritable bowel syndrome: a systematic review and meta-analysis.

Journal: The American journal of gastroenterology 20120101

Title: [Treatment of recurrent Clostridium difficile diarrhoea using sequential therapy with vancomycin followed by rifaximin].

Journal: Revista espanola de geriatria y gerontologia 20120101

Title: [Diagnostics and treatment of hepatic encephalopathy].

Journal: Deutsche medizinische Wochenschrift (1946) 20120101

Title: Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis.

Journal: PloS one 20120101

Title: [Role of rifaximin in the treatment of colonic diverticular disease].

Journal: La Clinica terapeutica 20120101

Title: Ammonia abolishers: antibiotics for hepatic encephalopathy.

Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20120101

Title: Effectiveness of rifaximin and fluoroquinolones in preventing travelers' diarrhea (TD): a systematic review and meta-analysis.

Journal: Systematic reviews 20120101

Title: A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection.

Journal: The Journal of antimicrobial chemotherapy 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: [Rifaximin for hepatic encephalopathy in children. Case report].

Journal: Archivos argentinos de pediatria 20111201

Title: Pharmacological treatment of abdominal pain related functional gastrointestinal disorders.

Journal: Journal of pediatric gastroenterology and nutrition 20111201

Title: In vitro activity of rifaximin against Chlamydia suis.

Journal: The Veterinary record 20111126

Title: Rifaximin in the treatment of inflammatory bowel disease.

Journal: World journal of gastroenterology 20111114

Title: Expanding applications: the potential usage of 5-aminosalicylic acid in diverticular disease.

Journal: Digestive diseases and sciences 20111101

Title: Colonic hypersensitivity is a major determinant of the efficacy of bloating treatment in constipation-predominant irritable bowel syndrome.

Journal: Internal and emergency medicine 20111001

Title: Double-blind randomized controlled trial of rifaximin for persistent symptoms in patients with celiac disease.

Journal: Digestive diseases and sciences 20111001

Title: Inhibition of NF-κB by a PXR-dependent pathway mediates counter-regulatory activities of rifaximin on innate immunity in intestinal epithelial cells.

Journal: European journal of pharmacology 20111001

Title: Randomised clinical trial: rifaximin improves health-related quality of life in cirrhotic patients with hepatic encephalopathy - a double-blind placebo-controlled study.

Journal: Alimentary pharmacology & therapeutics 20111001

Title: Treatment of diverticular disease of the colon and prevention of acute diverticulitis: a systematic review.

Journal: Diseases of the colon and rectum 20111001

Title: Rifaximin disc diffusion test for in vitro susceptibility testing of Clostridium difficile.

Journal: Journal of medical microbiology 20110801

Title: The role of rifaximin therapy in patients with irritable bowel syndrome without constipation.

Journal: Expert review of gastroenterology & hepatology 20110801

Title: Chronic prostatitis and small intestinal bacterial overgrowth: effect of rifaximin.

Journal: The Canadian journal of urology 20110801

Title: Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Journal: Journal of medicinal chemistry 20110714

Title: Antibiotic prophylaxis prevents the development of a post-infectious phenotype in a new rat model of post-infectious IBS.

Journal: Digestive diseases and sciences 20110701

Title: Effects of rifaximin treatment and retreatment in nonconstipated IBS subjects.

Journal: Digestive diseases and sciences 20110701

Title: A new use for Xifaxan.

Journal: The Nurse practitioner 20110701

Title: Rifaximin: new therapeutic indication and future directions.

Journal: Clinical therapeutics 20110701

Title: Is bacterial DNA a better marker than endotoxin of bacterial translocation in decompensated cirrhosis?

Journal: Hepatology (Baltimore, Md.) 20110601

Title: Antibiotic treatment may ease symptoms of irritable bowel syndrome.

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Title: Small intestinal bacterial overgrowth and Helicobacter pylori: can they be cause of thrombocytopenia in patients with chronic liver disease?

Journal: The American journal of gastroenterology 20110601

Title: Efficacy of levofloxacin and rifaximin based quadruple therapy in Helicobacter pylori associated gastroduodenal disease: a double-blind, randomized controlled trial.

Journal: Journal of Korean medical science 20110601

Title: Review of the final report of the 1998 Working Party on definition, nomenclature and diagnosis of hepatic encephalopathy.

Journal: Annals of hepatology 20110601

Title: Comment on: Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system.

Journal: The Journal of antimicrobial chemotherapy 20110501

Title: Probable interaction between warfarin and rifaximin in a patient treated for small intestine bacterial overgrowth.

Journal: The Annals of pharmacotherapy 20110501

Title: Rifaximin for irritable bowel syndrome without constipation.

Journal: The New England journal of medicine 20110414

Title: Rifaximin for irritable bowel syndrome without constipation.

Journal: The New England journal of medicine 20110414

Title: Double-blind, placebo-controlled antibiotic treatment study of small intestinal bacterial overgrowth in children with chronic abdominal pain.

Journal: Journal of pediatric gastroenterology and nutrition 20110401

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Title: Treatment of hepatic encephalopathy with rifaximin: more to think about.

Journal: Hepatology (Baltimore, Md.) 20110301

Title: Rifaximin improves driving simulator performance in a randomized trial of patients with minimal hepatic encephalopathy.

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Title: Rifaximin improves psychometric performance and health-related quality of life in patients with minimal hepatic encephalopathy (the RIME Trial).

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Title: Biologic properties and clinical uses of rifaximin.

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Journal: Journal of medicinal chemistry 20110113

Title: Rifaximin therapy for patients with irritable bowel syndrome without constipation.

Journal: The New England journal of medicine 20110106

Title: Antibiotic therapy for the irritable bowel syndrome.

Journal: The New England journal of medicine 20110106

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Rifaximin intake leads to emergence of rifampin-resistant staphylococci.

Journal: The Journal of infection 20110101

Title: [Rifaximin in combined treatment of the Helicobacter pylori infection in childhood].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

Title: [Rifaximin application in the overgrowth bacterial syndrome in the small intestine in patients after cholecystectomy].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101

Title: A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry season.

Journal: Journal of travel medicine 20110101

Title: [Optimization of treatment of patients with chronic cardiac insufficiency of the ischemic genesis and hobnail liver].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

Title: [Efficacy of rifaximine in small intestinal bacterial overgrowth syndrome in patients after cholecystectomy].

Journal: Terapevticheskii arkhiv 20110101

Title: Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells.

Journal: Biochemical pharmacology 20101201

Title: Rifaximin modulates the colonic microbiota of patients with Crohn's disease: an in vitro approach using a continuous culture colonic model system.

Journal: The Journal of antimicrobial chemotherapy 20101201

Title: Rifaximin for the treatment of hepatic encephalopathy.

Journal: Expert review of gastroenterology & hepatology 20101201

Title: Thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count.

Journal: The American journal of gastroenterology 20101201

Title: Rifaximin for the treatment of hepatic encephalopathy.

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Title: Rifaximin (Xifaxan 550) for hepatic encephalopathy.

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Title: Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation.

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Journal: Hepatology (Baltimore, Md.) 20101001

Title: Clinical trial: the combination of rifaximin with partially hydrolysed guar gum is more effective than rifaximin alone in eradicating small intestinal bacterial overgrowth.

Journal: Alimentary pharmacology & therapeutics 20101001

Title: A combination of rifaximin and neomycin is most effective in treating irritable bowel syndrome patients with methane on lactulose breath test.

Journal: Journal of clinical gastroenterology 20100901

Title: Bile acids improve the antimicrobial effect of rifaximin.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Rifaximin in hepatic encephalopathy: more than just a non-absorbable antibiotic?

Journal: Journal of hepatology 20100901

Title: Mechanisms, diagnosis and management of hepatic encephalopathy.

Journal: Nature reviews. Gastroenterology & hepatology 20100901

Title: Cyclic antibiotic therapy for diverticular disease: a critical reappraisal.

Journal: Journal of gastrointestinal and liver diseases : JGLD 20100901

Title: Rifaximin for the treatment of recurrent Clostridium difficile infection after liver transplantation: A case series.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100801

Title: Rifaximin diminishes neutropenia following potentially lethal whole-body radiation.

Journal: Experimental biology and medicine (Maywood, N.J.) 20100701

Title: Rifaximin: a nonsystemic rifamycin antibiotic for gastrointestinal infections.

Journal: Expert review of anti-infective therapy 20100701

Title: Rifaximin treatment in hepatic encephalopathy.

Journal: The New England journal of medicine 20100624

Title: Rifaximin treatment in hepatic encephalopathy.

Journal: The New England journal of medicine 20100624

Title: Rifaximin treatment in hepatic encephalopathy.

Journal: The New England journal of medicine 20100624

Title: Treatment and prevention of pouchitis after ileal pouch-anal anastomosis for chronic ulcerative colitis.

Journal: The Cochrane database of systematic reviews 20100616

Title: Persistent portosystemic shunts after liver transplantation causing episodic hepatic encephalopathy.

Journal: Digestive diseases and sciences 20100601

Title: Increased incidence of small intestinal bacterial overgrowth during proton pump inhibitor therapy.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20100601

Title: Review article: rifaximin, a minimally absorbed oral antibacterial, for the treatment of travellers' diarrhoea.

Journal: Alimentary pharmacology & therapeutics 20100601

Title: Pharmacotherapy of hepatic encephalopathy in cirrhosis.

Journal: Expert opinion on pharmacotherapy 20100601

Title: Rifaximin for inflammatory bowel disease.

Journal: Digestive diseases and sciences 20100601

Title: [Chronic diverticular diseases. Rifaximin reduces symptoms and complications].

Journal: MMW Fortschritte der Medizin 20100527

Title: Factors affecting compliance and persistence with treatment for hepatic encephalopathy.

Journal: Pharmacotherapy 20100501

Title: Pharmacoeconomics of hepatic encephalopathy.

Journal: Pharmacotherapy 20100501

Title: Clostridium difficile infection: update on emerging antibiotic treatment options and antibiotic resistance.

Journal: Expert review of anti-infective therapy 20100501

Title: Antibiotic therapy may improve idiopathic restless legs syndrome: prospective, open-label pilot study of rifaximin, a nonsystemic antibiotic.

Journal: Sleep medicine 20100401

Title: Adjunctive antibiotic therapy with rifaximin may help reduce Crohn's disease activity.

Journal: Digestive diseases and sciences 20100401

Title: Rifaximin and Crohn's disease: a new solution to an old problem?

Journal: Digestive diseases and sciences 20100401

Title: In vitro susceptibility of Clostridium difficile to rifaximin and rifampin in 359 consecutive isolates at a university hospital in Houston, Texas.

Journal: Journal of clinical pathology 20100401

Title: Rifaximin treatment in hepatic encephalopathy.

Journal: The New England journal of medicine 20100325

Title: Gut flora and hepatic encephalopathy in patients with cirrhosis.

Journal: The New England journal of medicine 20100325

Title: Structural elucidation of the Rifaximin Ph. Eur. Impurity H.

Journal: Journal of pharmaceutical and biomedical analysis 20100311

Title: Review article: the modern management of hepatic encephalopathy.

Journal: Alimentary pharmacology & therapeutics 20100301

Title: Rifaximin-induced alteration of virulence of diarrhoea-producing Escherichia coli and Shigella sonnei.

Journal: International journal of antimicrobial agents 20100301

Title: Rifaximin and nonabsorbable disaccharides for hepatic encephalopathy.

Journal: European journal of gastroenterology & hepatology 20100301

Title: Stability of extemporaneously prepared rifaximin oral suspensions.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100215

Title: Bacterial diarrhea.

Journal: The New England journal of medicine 20100211

Title: Diverticular disease: what is the best long-term treatment?

Journal: Nature reviews. Gastroenterology & hepatology 20100201

Title: Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases.

Journal: Current opinion in gastroenterology 20100101

Title: Saccharomyces boulardii plus rifaximin in mesalamine-intolerant ulcerative colitis.

Journal: Journal of clinical gastroenterology 20100101

Title: Prevention of travelers' diarrhea with rifaximin in US travelers to Mexico.

Journal: Journal of travel medicine 20100101

Title: [Efficacy of rifaksimin in excessive bacterial growth syndrome after cholecystectomy].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

Title: A randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of rifaximin for the prevention of travelers' diarrhea in US military personnel deployed to Incirlik Air Base, Incirlik, Turkey.

Journal: Journal of travel medicine 20100101

Title: Rifaximin Redux: treatment of recurrent Clostridium difficile infections with rifaximin immediately post-vancomycin treatment.

Journal: Anaerobe 20091201

Title: Rifaximin in the management of colonic diverticular disease.

Journal: Expert review of gastroenterology & hepatology 20091201

Title: On-line 2D-LC-ESI/MS/MS determination of rifaximin in rat serum.

Journal: Biomedical chromatography : BMC 20091101

Title: Alcoholic hepatitis.

Journal: The New England journal of medicine 20091008

Title: Use and safety of rifaximin in children with inflammatory bowel disease.

Journal: Journal of pediatric gastroenterology and nutrition 20091001

Title: Review article: the current and evolving treatment of colonic diverticular disease.

Journal: Alimentary pharmacology & therapeutics 20090915

Title: A randomized, double-blind, placebo-controlled trial of rifaximin, a nonabsorbable antibiotic, in the treatment of tropical enteropathy.

Journal: The American journal of gastroenterology 20090901

Title: IgE-mediated reactions to rifaximin and rifamycin SV and cross-reactivity among rifamycins.

Journal: Allergy 20090801

Title: Hepatic encephalopathy: pathophysiology and emerging therapies.

Journal: The Medical clinics of North America 20090701

Title: FPIN's Clinical Inquiries: Effective management of flatulence.

Journal: American family physician 20090615

Title: Small intestine bacterial overgrowth and irritable bowel syndrome-related symptoms: experience with Rifaximin.

Journal: World journal of gastroenterology 20090607

Title: Rapid determination of rifaximin in rat serum and urine by direct injection on to a shielded hydrophobic stationary phase by HPLC.

Journal: Biomedical chromatography : BMC 20090601

Title: Rifaximin pharmacology and clinical implications.

Journal: Expert opinion on drug metabolism & toxicology 20090601

Title: [Evidence-based therapy of irritable bowel syndrome. Intestine selective antibiotic relieves symptoms significantly].

Journal: MMW Fortschritte der Medizin 20090521

Title: Intestinal decontamination improves liver haemodynamics in patients with alcohol-related decompensated cirrhosis.

Journal: Alimentary pharmacology & therapeutics 20090501

Title: Treatment of cryptosporidiosis.

Journal: Expert review of anti-infective therapy 20090501

Title: Immunoregulatory activity of rifaximin associated with a resistant mutant of Bifidobacterium infantis.

Journal: International journal of antimicrobial agents 20090401

Title: Review of rifaximin as treatment for SIBO and IBS.

Journal: Expert opinion on investigational drugs 20090301

Title: Mesalazine and rifaximin in symptomatic uncomplicated diverticular disease.

Journal: The American journal of gastroenterology 20090201

Title: Rifaximin in treatment of recurrent Clostridium difficile-associated diarrhea: an uncontrolled pilot study.

Journal: Journal of clinical gastroenterology 20090101

Title: Involvement of central immunity in uncomplicated diverticular disease.

Journal: Scandinavian journal of gastroenterology 20090101

Title: Faecal calprotectin in colonic diverticular disease: a case-control study.

Journal: International journal of colorectal disease 20090101

Title: Rifaximin for treatment of hepatic encephalopathy.

Journal: The Annals of pharmacotherapy 20090101

Title: Antibiotic therapy in small intestinal bacterial overgrowth: rifaximin versus metronidazole.

Journal: European review for medical and pharmacological sciences 20090101

Title: Positive glucose breath testing is more prevalent in patients with IBS-like symptoms compared with controls of similar age and gender distribution.

Journal: Journal of clinical gastroenterology 20090101

Title: [Evaluation of alpha-normiks (rifaximin) efficacy in the treatment of patients with diverticular disease associated with medium and severe intestinal dysbacteriosis].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

Title: The role of rifaximin in the treatment and chemoprophylaxis of travelers' diarrhea.

Journal: Therapeutics and clinical risk management 20090101

Title: [Rifaksimin in complex treatment of Helicobacter pylori infection in children (a pilot study)].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

Title: [Bacterially induced traveler's diarrhea. Local antibiosis effective without systemic effects].

Journal: MMW Fortschritte der Medizin 20081106

Title: Rifaximin versus nonabsorbable disaccharides in the management of hepatic encephalopathy: a meta-analysis.

Journal: European journal of gastroenterology & hepatology 20081101

Title: Rifaximin for the treatment of hepatic encephalopathy.

Journal: Pharmacotherapy 20080801

Title: Rifaximin for the treatment of newly diagnosed Crohn's disease: a case series.

Journal: The American journal of gastroenterology 20080801

Title: Small intestinal bacterial overgrowth recurrence after antibiotic therapy.

Journal: The American journal of gastroenterology 20080801

Title: Small intestinal bacterial overgrowth in rosacea: clinical effectiveness of its eradication.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20080701

Title: Resolution of severe cryptosporidial diarrhea with rifaximin in patients with AIDS.

Journal: Journal of acquired immune deficiency syndromes (1999) 20080701

Title: Molecular and phenotypic traits of in-vitro-selected mutants of Bifidobacterium resistant to rifaximin.

Journal: International journal of antimicrobial agents 20080601

Title: Small intestinal bacterial overgrowth in patients with interstitial cystitis and gastrointestinal symptoms.

Journal: Digestive diseases and sciences 20080501

Title: Restless legs syndrome in patients with irritable bowel syndrome: response to small intestinal bacterial overgrowth therapy.

Journal: Digestive diseases and sciences 20080501

Title: Systematic review: prevention of travellers' diarrhoea.

Journal: Alimentary pharmacology & therapeutics 20080501

Title: Development of Escherichia coli rifaximin-resistant mutants: frequency of selection and stability.

Journal: The Journal of antimicrobial chemotherapy 20080501

Title: Small intestinal bacterial overgrowth in patients suffering from scleroderma: clinical effectiveness of its eradication.

Journal: The American journal of gastroenterology 20080501

Title: Rifaximin for the treatment of hepatic encephalopathy.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080501

Title: Effects of rifaximin on bacterial virulence mechanisms at supra- and sub-inhibitory concentrations.

Journal: Journal of chemotherapy (Florence, Italy) 20080401

Title: Rifaximin treatment for symptoms of irritable bowel syndrome.

Journal: The Annals of pharmacotherapy 20080301

Title: Rifaximin versus other antibiotics in the primary treatment and retreatment of bacterial overgrowth in IBS.

Journal: Digestive diseases and sciences 20080101

Title: 'Ecologic niche' therapy for Crohn's disease with adjunctive rifaximin antibiotic treatment followed by Flora-Q probiotic maintenance therapy.

Journal: The American journal of gastroenterology 20080101

Title: Rifaximin for maintenance therapy in antibiotic-dependent pouchitis.

Journal: BMC gastroenterology 20080101

Title: In vitro antimicrobial activity of rifaximin against enteropathogens causing traveler's diarrhea.

Journal: Diagnostic microbiology and infectious disease 20071201

Title: Microbial host interactions in IBD: implications for pathogenesis and therapy.

Journal: Current gastroenterology reports 20071201

Title: Association between hypothyroidism and small intestinal bacterial overgrowth.

Journal: The Journal of clinical endocrinology and metabolism 20071101

Title: The cost-effectiveness and budget impact of competing therapies in hepatic encephalopathy - a decision analysis.

Journal: Alimentary pharmacology & therapeutics 20071015

Title: Rifaximin for the treatment of active pouchitis: a randomized, double-blind, placebo-controlled pilot study.

Journal: Inflammatory bowel diseases 20071001

Title: The effect of multiple-dose, oral rifaximin on the pharmacokinetics of intravenous and oral midazolam in healthy volunteers.

Journal: Pharmacotherapy 20071001

Title: Rifaximin is a gut-specific human pregnane X receptor activator.

Journal: The Journal of pharmacology and experimental therapeutics 20070701

Title: Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide.

Journal: The Journal of the Oklahoma State Medical Association 20070701

Title: Review article: the role of antibiotics vs. conventional pharmacotherapy in treating symptoms of irritable bowel syndrome.

Journal: Alimentary pharmacology & therapeutics 20070601

Title: Sensitive quantification of rifaximin in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

Title: Genetic and proteomic characterization of rifaximin resistance in Bifidobacterium infantis BI07.

Journal: Research in microbiology 20070501

Title: Efficacy of rifaximin, a nonabsorbed oral antibiotic, in the treatment of small intestinal bacterial overgrowth.

Journal: The American journal of the medical sciences 20070501

Title: Interaction between rifaximin and dietary fibre in patients with diverticular disease.

Journal: Alimentary pharmacology & therapeutics 20070401

Title: High dosage rifaximin for the treatment of small intestinal bacterial overgrowth.

Journal: Alimentary pharmacology & therapeutics 20070401

Title: Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070401

Title: Interruption of recurrent Clostridium difficile-associated diarrhea episodes by serial therapy with vancomycin and rifaximin.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315

Title: Hospitalizations during the use of rifaximin versus lactulose for the treatment of hepatic encephalopathy.

Journal: Digestive diseases and sciences 20070301

Title: Can we ignore minimal hepatic encephalopathy any longer?

Journal: Hepatology (Baltimore, Md.) 20070301

Title: Antibiotic may improve irritable bowel syndrome.

Journal: Mayo Clinic health letter (English ed.) 20070301

Title: Absence of effect of oral rifaximin on the pharmacokinetics of ethinyl estradiol/norgestimate in healthy females.

Journal: The Annals of pharmacotherapy 20070201

Title: Review article: the current pharmacological therapies for hepatic encephalopathy.

Journal: Alimentary pharmacology & therapeutics 20070201

Title: Efficacy of long term cyclic administration of the poorly absorbed antibiotic Rifaximin in symptomatic, uncomplicated colonic diverticular disease.

Journal: World journal of gastroenterology 20070114

Title: Treatment of patients with irritable bowel syndrome.

Journal: American family physician 20070101

Title: Rifaximin treatment of pathogen-negative travelers' diarrhea.

Journal: Journal of travel medicine 20070101

Title: Quality of life in uncomplicated symptomatic diverticular disease: is it another good reason for treatment?

Journal: Digestive diseases (Basel, Switzerland) 20070101

Title: Efficacy of rifaximin and vancomycin combination therapy in a patient with refractory Clostridium difficile-associated diarrhea.

Journal: Journal of clinical gastroenterology 20070101

Title: Results of small intestinal bacterial overgrowth testing in irritable bowel syndrome patients: clinical profiles and effects of antibiotic trial.

Journal: Advances in medical sciences 20070101

Title: Emerging therapies in the treatment of Clostridium difficile-associated disease.

Journal: The Annals of pharmacotherapy 20061201

Title: Analysis of hospitalizations comparing rifaximin versus lactulose in the management of hepatic encephalopathy.

Journal: Transplantation proceedings 20061201

Title: Targeting intestinal microflora in inflammatory bowel disease.

Journal: World journal of gastroenterology 20061128

Title: [Significance of gastrointestinal antibiotics in gastrointestinal diseases: Normix, the non-absorbable antibiotic].

Journal: Orvosi hetilap 20061022

Title: Summaries for patients. Can antibiotics improve the symptoms of the irritable bowel syndrome?

Journal: Annals of internal medicine 20061017

Title: The effect of a nonabsorbed oral antibiotic (rifaximin) on the symptoms of the irritable bowel syndrome: a randomized trial.

Journal: Annals of internal medicine 20061017

Title: Rifaximin: an alternative for the treatment of hepatic encephalopathy.

Journal: Connecticut medicine 20060901

Title: Role of gut microflora and probiotic effects in the irritable bowel syndrome.

Journal: Acta bio-medica : Atenei Parmensis 20060801

Title: A randomized, double-blind, multicenter study of rifaximin compared with placebo and with ciprofloxacin in the treatment of travelers' diarrhea.

Journal: The American journal of tropical medicine and hygiene 20060601

Title: Current and future developments in travelers' diarrhea therapy.

Journal: Expert review of anti-infective therapy 20060601

Title: Review article: uncomplicated diverticular disease of the colon.

Journal: Alimentary pharmacology & therapeutics 20060515

Title: Rifaximin, a nonabsorbed oral antibiotic, prevents shigellosis after experimental challenge.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060501

Title: Prevention of first overt episode of hepatic encephalopathy after TIPS: no easy task.

Journal: Hepatology (Baltimore, Md.) 20060501

Title: What's new in clinical pharmacology and therapeutics.

Journal: WMJ : official publication of the State Medical Society of Wisconsin 20060501

Title: Antibiotic treatment of Crohn's disease: results of a multicentre, double blind, randomized, placebo-controlled trial with rifaximin.

Journal: Alimentary pharmacology & therapeutics 20060415

Title: Rifaximin for active ulcerative colitis.

Journal: Inflammatory bowel diseases 20060401

Title: Small intestine bacterial overgrowth in irritable bowel syndrome: a retrospective study with rifaximin.

Journal: Minerva gastroenterologica e dietologica 20060301

Title: Transient lactose malabsorption in patients affected by symptomatic uncomplicated diverticular disease of the colon.

Journal: Digestive diseases and sciences 20060301

Title: [Modern indications on the medical treatment of symptomatic diverticular disease].

Journal: Il Giornale di chirurgia 20060301

Title: Rifaximin: a novel nonabsorbed rifamycin for gastrointestinal disorders.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060215

Title: A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence.

Journal: The American journal of gastroenterology 20060201

Title: Germs, gas and the gut; the evolving role of the enteric flora in IBS.

Journal: The American journal of gastroenterology 20060201

Title: [The use of Rifaximin in daily clinical practice].

Journal: Orvosi hetilap 20060122

Title: [Diverticulosis/diverticulitis? What are conservative therapy possibilities?].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20060115

Title: Experimental and clinical pharmacology of rifaximin, a gastrointestinal selective antibiotic.

Journal: Digestion 20060101

Title: Management of hepatic encephalopathy: focus on antibiotic therapy.

Journal: Digestion 20060101

Title: Eradication of Helicobacter pylori: are rifaximin-based regimens effective?

Journal: Digestion 20060101

Title: Safety and tolerability of the antibacterial rifaximin in the treatment of travellers' diarrhoea.

Journal: Drug safety 20060101

Title: Travellers' diarrhoea: contemporary approaches to therapy and prevention.

Journal: Drugs 20060101

Title: Rifaximin-based regimens for eradication of Helicobacter pylori: a pilot study.

Journal: Digestive diseases (Basel, Switzerland) 20060101

Title: Rifaximin (Xifaxan) for traveler's diarrhea.

Journal: American family physician 20051215

Title: Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment.

Journal: Current opinion in infectious diseases 20051201

Title: Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximin.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051201

Title: Colonic diverticular disease.

Journal: Clinical evidence 20051201

Title: Rifaximin--the promising anti-microbial for enteric infections.

Journal: The Journal of infection 20051001

Title: A dance teacher with kidney-pancreas transplant and diarrhoea: what is the cause?

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801

Title: An open-label evaluation of rifaximin in the treatment of active Crohn's disease.

Journal: Current medical research and opinion 20050801

Title: Rifaximin dose-finding study for the treatment of small intestinal bacterial overgrowth.

Journal: Alimentary pharmacology & therapeutics 20050701

Title: Comparison of rifaximin and lactulose for the treatment of hepatic encephalopathy: a prospective randomized study.

Journal: Yonsei medical journal 20050630

Title: Epithelial cell proliferation of the colonic mucosa in diverticular disease: a case-control study.

Journal: Alimentary pharmacology & therapeutics 20050601

Title: Summaries for patients. Can a new antibiotic safely prevent travelers' diarrhea?

Journal: Annals of internal medicine 20050517

Title: A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrhea.

Journal: Annals of internal medicine 20050517

Title: How to hit the runs for fifty million travelers at risk.

Journal: Annals of internal medicine 20050517

Title: Pharmacological prophylaxis of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt: a randomized controlled study.

Journal: Journal of hepatology 20050501

Title: Rifaximin in patients with lactose intolerance.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050501

Title: Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome.

Journal: Alimentary pharmacology & therapeutics 20050415

Title: Rifaximin: a nonabsorbable rifamycin antibiotic for use in nonsystemic gastrointestinal infections.

Journal: Expert review of anti-infective therapy 20050401

Title: Rifaximin-ciprofloxacin combination therapy is effective in chronic active refractory pouchitis.

Journal: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20050301

Title: Efficacy of mesalazine in the treatment of symptomatic diverticular disease.

Journal: Digestive diseases and sciences 20050301

Title: Rifaximin: a new treatment for travelers' diarrhea.

Journal: The Annals of pharmacotherapy 20050201

Title: Rifaximin--a novel antimicrobial for enteric infections.

Journal: The Journal of infection 20050201

Title: 2004 drug approval highlights: FDA update.

Journal: The Nurse practitioner 20050201

Title: Mesalazine for diverticular disease of the colon--a new role for an old drug.

Journal: Expert opinion on pharmacotherapy 20050101

Title: Rifaximin: a nonabsorbed oral antibiotic.

Journal: Reviews in gastroenterological disorders 20050101

Title: Rifaximin, a poorly absorbed antibiotic: pharmacology and clinical potential.

Journal: Chemotherapy 20050101

Title: Rifaximin: in vitro and in vivo antibacterial activity--a review.

Journal: Chemotherapy 20050101

Title: Rifaximin in the treatment of infectious diarrhea.

Journal: Chemotherapy 20050101

Title: Management of hepatic encephalopathy: role of rifaximin.

Journal: Chemotherapy 20050101

Title: Management of inflammatory bowel disease: does rifaximin offer any promise?

Journal: Chemotherapy 20050101

Title: Treatment of small intestine bacterial overgrowth and related symptoms by rifaximin.

Journal: Chemotherapy 20050101

Title: Management of diverticular disease: is there room for rifaximin?

Journal: Chemotherapy 20050101

Title: Rifaximin, a peculiar rifamycin derivative: established and potential clinical use outside the gastrointestinal tract.

Journal: Chemotherapy 20050101

Title: Rifaximin, a nonabsorbed oral antibiotic, in the treatment of hepatic encephalopathy: antimicrobial activity, efficacy, and safety.

Journal: Reviews in gastroenterological disorders 20050101

Title: Rifaximin: a review of its use in the management of traveller's diarrhoea.

Journal: Drugs 20050101

Title: Evaluation of rifaximin, placebo and lactulose in reducing the levels of benzodiazepine-like compounds in patients with liver cirrhosis: a pilot study.

Journal: Drugs under experimental and clinical research 20050101

Title: Colonic diverticular disease.

Journal: Clinical evidence 20041201

Title: Influence of rifaximin treatment on the susceptibility of intestinal Gram-negative flora and enterococci.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20041101

Title: [Clinical and pharmacological aspects of rifaximin, local antibiotic therapy in intestinal disorders].

Journal: Orvosi hetilap 20041024

Title: Rifaximin (Xifaxan) for travelers' diarrhea.

Journal: The Medical letter on drugs and therapeutics 20040913

Title: New drugs and dosage forms.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040715

Title: [Rifaximin].

Journal: Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20040601

Title: Colonic diverticular disease.

Journal: Clinical evidence 20040601

Title: Acute recurrent diverticulitis is prevented by oral administration of a polybacterial lysate suspension.

Journal: Minerva gastroenterologica e dietologica 20040601

Title: Solution structure of rifaximin and its synthetic derivative rifaximin OR determined by experimental NMR and theoretical simulation methods.

Journal: Bioorganic & medicinal chemistry 20040501

Title: Rifaximin plus mesalazine followed by mesalazine alone is highly effective in obtaining remission of symptomatic uncomplicated diverticular disease.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040501

Title: CXC and CC chemokine expression in inflamed and noninflamed pelvic ileal pouch tissue.

Journal: International journal of colorectal disease 20040301

Title: Enteroaggregative Escherichia coli diarrhea in travelers: response to rifaximin therapy.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040201

Title: [Evaluation of Helicobacter pylori susceptibility to rifaximin].

Journal: Gastroenterologia y hepatologia 20040101

Title: Does rifaximin prevent complications of diverticular disease? A retrospective study.

Journal: European review for medical and pharmacological sciences 20040101

Title: Susceptibility to rifaximin of Vibrio cholerae strains from different geographical areas.

Journal: The Journal of antimicrobial chemotherapy 20030801

Title: Colonic diverticular disease.

Journal: Clinical evidence 20030601

Title: Therapy of travelers' diarrhea with rifaximin on various continents.

Journal: The American journal of gastroenterology 20030501

Title: Rifaximin improves symptoms of acquired uncomplicated diverticular disease of the colon.

Journal: International journal of colorectal disease 20030101

Title: Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial.

Journal: Journal of hepatology 20030101

Title: Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020701

Title: Effects of rifaximin administration on the intestinal microbiota in patients with ulcerative colitis.

Journal: Journal of chemotherapy (Florence, Italy) 20020601

Title: [Rifaximin in the treatment of hepatic encephalopathy].

Journal: Vnitrni lekarstvi 20020601

Title: Colonic diverticular disease.

Journal: Clinical evidence 20020601

Title: Eradication of small intestinal bacterial overgrowth and oro-cecal transit in diabetics.

Journal: Hepato-gastroenterology 20020101

Title: Inhibition of intestinal bacterial translocation with rifaximin modulates lamina propria monocytic cells reactivity and protects against inflammation in a rodent model of colitis.

Journal: Digestion 20020101

Title: Rifaximin versus ciprofloxacin for the treatment of traveler's diarrhea: a randomized, double-blind clinical trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011201

Title: Rifaximin: a new approach to the treatment of travelers' diarrhea. Introduction.

Journal: Journal of travel medicine 20011201

Title: Treatment of travelers' diarrhea.

Journal: Journal of travel medicine 20011201

Title: Rifaximin: a nonabsorbed antimicrobial as a new tool for treatment of travelers' diarrhea.

Journal: Journal of travel medicine 20011201

Title: Rifaximin: a new approach to the treatment of travelers' diarrhea. Conclusion.

Journal: Journal of travel medicine 20011201

Title: Effects of daily oral administration of rifaximin and neomycin on faecal aerobic flora in rats.

Journal: Pharmacological research 20011101

Title: Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.

Journal: Immunopharmacology and immunotoxicology 20011101

Title: [Role of prebiotics and probiotics in therapeutic management of cryptogenetic inflammatory bowel disease].

Journal: Gastroenterologie clinique et biologique 20010901

Title: In vitro activity of rifaximin against bacterial enteropathogens causing diarrhoea in children under 5 years of age in Ifakara, Tanzania.

Journal: The Journal of antimicrobial chemotherapy 20010601

Title: Rifaximin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria.

Journal: Drugs 19950301

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