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25875-50-7,MFCD01724404
Catalog No.:AA00ILNY

25875-50-7 | Robenidine hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(HPLC)
in stock  
$127.00   $89.00
- +
5g
98%(HPLC)
in stock  
$231.00   $162.00
- +
25g
98%(HPLC)
in stock  
$572.00   $400.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ILNY
Chemical Name:
Robenidine hydrochloride
CAS Number:
25875-50-7
Molecular Formula:
C15H14Cl3N5
Molecular Weight:
370.6642
MDL Number:
MFCD01724404
SMILES:
N=C(N/N=C/c1ccc(cc1)Cl)N/N=C/c1ccc(cc1)Cl.Cl
Properties
Computed Properties
 
Complexity:
408  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
3  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ZHEJIANGESIGMABIOTECHNOLOGY-CN105294511,2016,ALocationinpatent:Paragraph0019;0020

[2]Stevens,AndrewJ.;Abraham,Rebecca;Young,KellyA.;Russell,CeciliaC.;McCluskey,SiobhannN.;Baker,JenniferR.;Rusdi,Bertha;Page,StephenW.;O'Handley,Ryan;O'Dea,Mark;Abraham,Sam;McCluskey,Adam[ChemMedChem,2022,vol.17,#21]

[3]Abraham,RebeccaJ.;Stevens,AndrewJ.;Young,KellyA.;Russell,Cecilia;Qvist,Anastasia;Khazandi,Manouchehr;Wong,HuiSan;Abraham,Sam;Ogunniyi,AbiodunD.;Page,StephenW.;O'Handley,Ryan;McCluskey,Adam;Trott,DarrenJ.[JournalofMedicinalChemistry,2016,vol.59,#5,p.2126-2138]

541-41-3    25875-50-7   
CASUnavailable 

[1]Abraham,RebeccaJ.;Stevens,AndrewJ.;Young,KellyA.;Russell,Cecilia;Qvist,Anastasia;Khazandi,Manouchehr;Wong,HuiSan;Abraham,Sam;Ogunniyi,AbiodunD.;Page,StephenW.;O'Handley,Ryan;McCluskey,Adam;Trott,DarrenJ.[JournalofMedicinalChemistry,2016,vol.59,#5,p.2126-2138]

25875-50-7    543-27-1   
CASUnavailable 

[1]Abraham,RebeccaJ.;Stevens,AndrewJ.;Young,KellyA.;Russell,Cecilia;Qvist,Anastasia;Khazandi,Manouchehr;Wong,HuiSan;Abraham,Sam;Ogunniyi,AbiodunD.;Page,StephenW.;O'Handley,Ryan;McCluskey,Adam;Trott,DarrenJ.[JournalofMedicinalChemistry,2016,vol.59,#5,p.2126-2138]

25875-50-7   
CASUnavailable 
 
CASUnavailable 

[1]Abraham,RebeccaJ.;Stevens,AndrewJ.;Young,KellyA.;Russell,Cecilia;Qvist,Anastasia;Khazandi,Manouchehr;Wong,HuiSan;Abraham,Sam;Ogunniyi,AbiodunD.;Page,StephenW.;O'Handley,Ryan;McCluskey,Adam;Trott,DarrenJ.[JournalofMedicinalChemistry,2016,vol.59,#5,p.2126-2138]

Literature

Title: Biotic transformation of anticoccidials in soil using a lab-scale bio-reactor as a precursor-tool.

Journal: Chemosphere 20120101

Title: In vitro destruction of Eimeria oocysts by essential oils.

Journal: Veterinary parasitology 20111215

Title: [Determination of robenidine residue in chicken tissues and eggs by high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20100901

Title: Fate and antibacterial potency of anticoccidial drugs and their main abiotic degradation products.

Journal: Environmental pollution (Barking, Essex : 1987) 20090201

Title: Effect of subcutaneously administered diclazuril on the output of Eimeria species oocysts by experimentally infected rabbits.

Journal: The Veterinary record 20080202

Title: Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis.

Journal: Amino acids 20070801

Title: Use of antigen mimics to produce specific antibodies to anti-coccidial drugs.

Journal: Journal of immunological methods 20070531

Title: Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase.

Journal: Biochemistry 20060627

Title: Binding-linked protonation of a DNA minor-groove agent.

Journal: Biophysical journal 20060215

Title: Characterization of a novel DNA minor-groove complex.

Journal: Biophysical journal 20040201

Title: Strong binding in the DNA minor groove by an aromatic diamidine with a shape that does not match the curvature of the groove.

Journal: Journal of the American Chemical Society 20021120

Title: The story of CGP 40 215: studies on its efficacy and pharmacokinetics in African green monkey infected with Trypanosoma brucei rhodesiense.

Journal: Tropical medicine & international health : TM & IH 20010501

Title: In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga.

Journal: Drugs under experimental and clinical research 20010101

Title: Abraham RJ, et al. Robenidine Analogues as Gram-Positive Antibacterial Agents. J Med Chem. 2016 Mar 10;59(5):2126-38.

Title: Liu C, et al. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits. Exp Anim. 2015;64(1):73-9.

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