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57852-57-0,MFCD00897212
Catalog No.:AA019FQD

57852-57-0 | Idarubicin Hydrochloride

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Purity
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1mg
≥98%
in stock  
$52.00   $36.00
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5mg
≥98%
in stock  
$122.00   $85.00
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10mg
≥98%
in stock  
$202.00   $141.00
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50mg
≥98%
in stock  
$765.00   $535.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA019FQD
Chemical Name:
Idarubicin Hydrochloride
CAS Number:
57852-57-0
Molecular Formula:
C26H28ClNO9
Molecular Weight:
533.9548
MDL Number:
MFCD00897212
SMILES:
O[C@H]1[C@@H](N)C[C@@H](O[C@H]1C)O[C@H]1C[C@@](O)(Cc2c1c(O)c1c(c2O)C(=O)c2c(C1=O)cccc2)C(=O)C.Cl
Properties
Properties
 
Form:
Solid  
MP:
>156°C (dec.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
912  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:SINOBIOPHARMACEUTICALLIMITED-CN107698634,2018,ALocationinpatent:Paragraph0042;0043

[2]Kimura,Yoshikazu;Suzuki,Michiyo;Matsumoto,Teruyo;Abe,Rumiko;Terashima,Shiro[ChemistryLetters,1984,p.501-504]

[3]CurrentPatentAssignee:SYNBIASPHARMA;SOLUX-US2004/236086,2004,A1Locationinpatent:Page4

[4]CurrentPatentAssignee:SYNBIASPHARMA-US2012/277415,2012,A1Locationinpatent:Page/Pagecolumn9

[5]CurrentPatentAssignee:ZHEJIANGYASEPHARMACEUTICAL-CN115785168,2023,ALocationinpatent:Paragraph0066-0067

[1]ChemistryLetters,1984,p.501-504

[2]ChemistryLetters,1984,p.501-504

[3]ChemistryLetters,1984,p.501-504

[1]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn8;10

[2]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn11-12

[3]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn12-13

[1]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn7-8

[2]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn8-10

[3]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn12

[4]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn11-12

[5]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn10-11

[6]Patent:US2007/4653,2007,A1.Locationinpatent:Page/Pagecolumn13

[1]CurrentPatentAssignee:SYNBIASPHARMA-US2012/277415,2012,A1Locationinpatent:Page/Pagecolumn8-9

Literature

Title: Dexrazoxane Averts Idarubicin-Evoked Genomic Damage by Regulating Gene Expression Profiling Associated With the DNA Damage-Signaling Pathway in BALB/c Mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20171101

Title: DNA-PKcs-dependent NHEJ pathway supports the progression of topoisomerase II poison-induced chromosome aberrant cells.

Journal: Environmental and molecular mutagenesis 20121001

Title: Acute myeloid leukaemia with abnormal eosinophil precursors without inversion 16.

Journal: British journal of haematology 20120901

Title: All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4).

Journal: Blood 20120823

Title: ATRA plus arsenic gets another 'A' in APL.

Journal: Blood 20120823

Title: Phase II trial of vorinostat with idarubicin and cytarabine for patients with newly diagnosed acute myelogenous leukemia or myelodysplastic syndrome.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120620

Title: Lytic bone disease as the presenting feature of Philadelphia-positive monosomy 7 myelodysplasia progressing to acute myeloid leukaemia.

Journal: Gene 20120615

Title: Prognostic significance of alterations in IDH enzyme isoforms in patients with AML treated with high-dose cytarabine and idarubicin.

Journal: Cancer 20120515

Title: RALLE pilot: response-guided therapy for marrow relapse in acute lymphoblastic leukemia in children.

Journal: Journal of pediatric hematology/oncology 20120501

Title: Myeloperoxidase expression in acute myeloid leukemia helps identifying patients to benefit from transplant.

Journal: Yonsei medical journal 20120501

Title: Therapy-related acute leukemia with mixed phenotype and t(9;22)(q32;q11.2): a case report and review of the literature.

Journal: Human pathology 20120401

Title: Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase: implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells.

Journal: Anti-cancer drugs 20120401

Title: Elacytarabine, a novel 5'-elaidic acid derivative of cytarabine, and idarubicin combination is active in refractory acute myeloid leukemia.

Journal: Leukemia research 20120401

Title: Smoking adversely affects survival in acute myeloid leukemia patients.

Journal: International journal of cancer 20120315

Title: Polypeptide conjugates of D-penicillamine and idarubicin for anticancer therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20120310

Title: Is obesity a prognostic factor for acute myeloid leukemia outcome?

Journal: Annals of hematology 20120301

Title: Unique association of systemic mastocytosis and myeloid/lymphoid neoplasm in blast crisis with abnormality of FGFR1 gene.

Journal: Leukemia research 20120301

Title: HPLC quantification of doxorubicin in plasma and tissues of rats treated with doxorubicin loaded poly(alkylcyanoacrylate) nanoparticles.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120301

Title: Phase II study of 2-chlorodeoxyadenosine plus idarubicin for children with acute myeloid leukaemia in first relapse: a paediatric oncology group study.

Journal: British journal of haematology 20120301

Title: [Current treatment of acute myeloid leukaemia in adults].

Journal: Orvosi hetilap 20120219

Title: Idarubicin-intensified BUCY2 regimens may lower relapse rate and improve survival in patients undergoing allo-SCT for high-risk hematological malignancies: a retrospective analysis.

Journal: Bone marrow transplantation 20120201

Title: Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells.

Journal: Journal of molecular medicine (Berlin, Germany) 20120201

Title: Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia.

Journal: Haematologica 20120201

Title: Oxidized phospholipid based pH sensitive micelles for delivery of anthracyclines to resistant leukemia cells in vitro.

Journal: International journal of pharmaceutics 20120117

Title: Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia.

Journal: Cancer 20120115

Title: Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols.

Journal: Blood 20120105

Title: The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells.

Journal: Anti-cancer drugs 20120101

Title: FLAGIDA-lite is an effective regimen for patients between 70 and 80 years with acute myeloid leukemia or refractory anemia with excess blasts-2 and is feasible as outpatient treatment.

Journal: American journal of hematology 20120101

Title: Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles.

Journal: Molecular pharmaceutics 20120101

Title: Oral low-dose chemotherapy: successful treatment of an alveolar rhabdomyosarcoma during pregnancy.

Journal: Pediatric blood & cancer 20120101

Title: Bullous leukaemia cutis.

Journal: European journal of dermatology : EJD 20120101

Title: Phase I study to determine the maximal tolerated dose and dose-limiting toxicities of orally administered idarubicin in dogs with lymphoma.

Journal: Journal of veterinary internal medicine 20120101

Title: High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery.

Journal: PloS one 20120101

Title: Subclinical anthracycline cardiotoxicity in patients with acute promyelocytic leukemia in long-term remission after the AIDA protocol.

Journal: Congestive heart failure (Greenwich, Conn.) 20120101

Title: t(4;22)(q12;q11.2) involving presumptive platelet-derived growth factor receptor A and break cluster region in a patient with mixed phenotype acute leukemia.

Journal: Human pathology 20111201

Title: Enhanced cellular delivery of idarubicin by surface modification of propyl starch nanoparticles employing pteroic acid conjugated polyvinyl alcohol.

Journal: International journal of pharmaceutics 20111125

Title: Phase 1 study of arsenic trioxide, high-dose cytarabine, and idarubicin to down-regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia.

Journal: Cancer 20111101

Title: Massive postpartum hemorrhage after chemotherapy in a patient with acute promyelocytic leukemia.

Journal: The journal of obstetrics and gynaecology research 20111101

Title: Do AML patients with DNMT3A exon 23 mutations benefit from idarubicin as compared to daunorubicin? A single center experience.

Journal: Oncotarget 20111101

Title: Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment.

Journal: Current cardiology reviews 20111101

Title: Treatment strategies in patients with core-binding factor acute myeloid leukemia.

Journal: Current oncology reports 20111001

Title: Comparative aneugenicity of doxorubicin and its derivative idarubicin using fluorescence in situ hybridization techniques.

Journal: Mutation research 20111001

Title: [Clinical study on combination of homoharringtonine, Ara-C and idarubicin induction for treatment of newly diagnosed acute myeloid leukemia patients].

Journal: Zhongguo shi yan xue ye xue za zhi 20111001

Title: GIMEMA AIDA 0493 amended protocol for elderly patients with acute promyelocytic leukaemia. Long-term results and prognostic factors.

Journal: British journal of haematology 20110901

Title: [Synergistic cytotoxic effects of rapamycin and idarubicin on human acute T-cell lymphoblastic leukemia Jurkat cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901

Title: AKR1B10 induces cell resistance to daunorubicin and idarubicin by reducing C13 ketonic group.

Journal: Toxicology and applied pharmacology 20110815

Title: Use of cytarabine and idarubicin in a newly diagnosed AML patient with a severe wound.

Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20110801

Title: Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia.

Journal: Pathology 20110801

Title: Patterns of molecular response to and relapse after combination of sorafenib, idarubicin, and cytarabine in patients with FLT3 mutant acute myeloid leukemia.

Journal: Clinical lymphoma, myeloma & leukemia 20110801

Title: Improving the outcomes of elderly patients with acute myeloid leukemia in a Brazilian University Hospital.

Journal: Clinics (Sao Paulo, Brazil) 20110801

Title: Fludarabine and cytarabine in patients with acute myeloid leukemia refractory to two different courses of front-line chemotherapy.

Journal: Leukemia research 20110701

Title: Inhibition of eIF4E with ribavirin cooperates with common chemotherapies in primary acute myeloid leukemia specimens.

Journal: Leukemia 20110701

Title: Backtracking to birth of the NUP98-HOXD13 gene fusion in an infant acute myeloid leukemia.

Journal: Leukemia 20110701

Title: Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia (AML): Japan Adult Leukemia Study Group (JALSG)-AML206 study.

Journal: Cancer science 20110701

Title: Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620

Title: Successful treatment of acute promyelocytic leukemia in a patient on hemodialysis.

Journal: Clinical and experimental nephrology 20110601

Title: Survivin overexpression correlates with an apoptosis-resistant phenotype in chronic myeloid leukemia cells.

Journal: Oncology reports 20110601

Title: AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance.

Journal: Blood 20110505

Title: Utility of myeloperoxidase stain in the differential diagnosis of leukemia cutis vs. hystiocitoid Sweet syndrome.

Journal: Dermatology online journal 20110415

Title: A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome.

Journal: Cancer 20110315

Title: Brucellosis: a rare cause of febrile neutropenia in acute myeloblastic leukemia.

Journal: Medical oncology (Northwood, London, England) 20110301

Title: High dose cytarabine plus gemtuzumab ozogamicin for patients with relapsed or refractory acute myeloid leukemia: Cancer and Leukemia Group B study 19902.

Journal: Leukemia research 20110301

Title: Early assessment of treatment response in patients with AML using [(18)F]FLT PET imaging.

Journal: Leukemia research 20110301

Title: Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110301

Title: Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study.

Journal: Blood 20110224

Title: Response-guided induction therapy in pediatric acute myeloid leukemia with excellent remission rate.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110120

Title: XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.

Journal: Apoptosis : an international journal on programmed cell death 20110101

Title: [Acute myelogenous leukemia developed at the 26th week of gestation].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20110101

Title: Miliaria-rash after neutropenic fever and induction chemotherapy for acute myelogenous leukemia.

Journal: Anais brasileiros de dermatologia 20110101

Title: Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.

Journal: Lancet (London, England) 20101211

Title: Mitoxantrone in first-relapse paediatric ALL: the ALL R3 trial.

Journal: Lancet (London, England) 20101211

Title: Clinical features and outcomes of 49 Turkish patients with acute promyelocytic leukemia who received ATRA and anthracyclines (PETHEMA protocol) therapy.

Journal: Leukemia research 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Acute promyelocytic leukemia during pregnancy.

Journal: Fertility and sterility 20101101

Title: Prognosis of secondary acute myeloid leukemia is affected by the type of the preceding hematologic disorders and the presence of trisomy 8.

Journal: Japanese journal of clinical oncology 20101101

Title: Chemotherapy: Lo and behold, a role for lomustine in acute myeloid leukemia?

Journal: Nature reviews. Clinical oncology 20101101

Title: Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group.

Journal: Blood 20101028

Title: Fatty acid based hyperbranched polymeric nanoparticles for hydrophobic drug delivery.

Journal: Drug development and industrial pharmacy 20101001

Title: Blood stream infections during chemotherapy-induced neutropenia in adult patients with acute myeloid leukemia: treatment cycle matters.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20101001

Title: Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin (FLAG-IDA) for the treatment of children with poor-prognosis acute leukemia: the Hacettepe experience.

Journal: Pediatric hematology and oncology 20101001

Title: Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association?

Journal: American journal of hematology 20101001

Title: [Leukemia cutis arising at the site of injection of a tetanus vaccine booster].

Journal: Actas dermo-sifiliograficas 20101001

Title: High efficacy and low toxicity of APL induction with concurrent idarubicin/ATRA followed by a novel and simplified outpatient post-remission therapy using single doses of idarubicin and intermittent ATRA.

Journal: Medical oncology (Northwood, London, England) 20100901

Title: Effect of post-remission chemotherapy preceding allogeneic hematopoietic cell transplant in patients with acute myeloid leukemia in first remission.

Journal: Leukemia & lymphoma 20100901

Title: Day 15 bone marrow driven double induction in young adult patients with acute myeloid leukemia: feasibility, toxicity, and therapeutic results.

Journal: American journal of hematology 20100901

Title: CNS relapse in acute promyeloctyic leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820

Title: The encapsulation of idarubicin within liposomes using the novel EDTA ion gradient method ensures improved drug retention in vitro and in vivo.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20100817

Title: Immunosuppressive treatments in Crohn's disease induce myelodysplasia and leukaemia.

Journal: American journal of hematology 20100801

Title: Treatment of acute promyelocytic leukemia with PETHEMA LPA 99 protocol: a Tunisian single center experience.

Journal: Hematology (Amsterdam, Netherlands) 20100801

Title: A case of ATRA-induced isolated myocarditis in the absence of circulating malignant cells: demonstration of the t(15;17) translocation in the inflammatory infiltrate by in situ hybridisation.

Journal: Leukemia research 20100701

Title: Complete molecular remission in refractory acute myeloid leukemia with MLL/AF9 treated with gemtuzumab ozogamicin.

Journal: Leukemia research 20100701

Title: Typhlitis due to mucormycosis after chemotherapy in a patient with acute myeloid leukemia.

Journal: Leukemia research 20100701

Title: Granulocytic sarcoma of abdomen in acute myeloid leukemia patient with inv(16) and t(6;17) abnormal chromosome: case report and review of literature.

Journal: Leukemia research 20100701

Title: Favorable outcome in patients with acute myelogenous leukemia with the nucleophosmin gene mutation autografted after conditioning with high-dose continuous infusion of idarubicin and busulfan.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100701

Title: Nanoparticles for local drug delivery to the oral mucosa: proof of principle studies.

Journal: Pharmaceutical research 20100701

Title: A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.

Journal: British journal of haematology 20100701

Title: Tandem versus single autologous peripheral blood stem cell transplantation as post-remission therapy in adult acute myeloid leukemia patients under 60 in first complete remission: results of the multicenter prospective phase III GOELAMS LAM-2001 trial.

Journal: Leukemia 20100701

Title: Leukaemia cutis at the site of striae distensae: an isotopic response?

Journal: Acta dermato-venereologica 20100701

Title: Addition of lomustine to idarubicin and cytarabine improves the outcome of elderly patients with de novo acute myeloid leukemia: a report from the GOELAMS.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100620

Title: Central line-associated bacteremia caused by drug-resistant Staphylococcus caprae after chemotherapy for acute myelogenous leukemia.

Journal: International journal of hematology 20100601

Title: Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100601

Title: Primary multiple cerebral invasion in acute promyelocytic leukemia dramatically worsened by all-trans retinoic acid.

Journal: Leukemia research 20100501

Title: Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia.

Journal: Haematologica 20100501

Title: Rapid response to induction in a case of acute promyelocytic leukemia with MYC amplification on double minutes at diagnosis.

Journal: Cancer genetics and cytogenetics 20100415

Title: Phase I/II study of combination therapy with sorafenib, idarubicin, and cytarabine in younger patients with acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410

Title: High body mass index is an independent predictor of differentiation syndrome in patients with acute promyelocytic leukemia.

Journal: Leukemia research 20100401

Title: Orbital mass as a presenting sign of acute leukemia.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20100401

Title: Microplate spectrophotometry for high-throughput screening of cytotoxic molecules.

Journal: Cell proliferation 20100401

Title: [Isolated relapse in the central nervous system during cytologic and hematologic remission in a patient with acute promyelocytic leukemia].

Journal: Neurologia (Barcelona, Spain) 20100401

Title: Leukemia cutis limited to the needle puncture sites.

Journal: The Journal of dermatology 20100401

Title: Successful treatment of severe gastrointestinal bleeding after chemotherapy in acute myeloblastic leukemia with recombinant activated factor VII : report on one case and review of other uses in acute leukemias.

Journal: Medical oncology (Northwood, London, England) 20100301

Title: Acute promyelocytic leukemia treated with idarubicin complicated by focal segmental glomerulosclerosis.

Journal: Journal of pediatric hematology/oncology 20100301

Title: Randomized trial of response-oriented individualized versus fixed-schedule induction chemotherapy with idarubicin and cytarabine in adult acute myeloid leukemia: the JALSG AML95 study.

Journal: International journal of hematology 20100301

Title: Intrathecal chemotherapy and meningeal relapses in myelomonocytic AML. A single institution experience.

Journal: American journal of hematology 20100301

Title: Toxic shock syndrome caused by hospital-acquired methicillin-resistant Staphylococcus aureus in a patient with pancytopenia.

Journal: Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20100301

Title: Fatal hepatitis B reactivation in an immune patient after anti-leukemic chemotherapy.

Journal: The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20100301

Title: Randomized study of intensified anthracycline doses for induction and recombinant interleukin-2 for maintenance in patients with acute myeloid leukemia age 50 to 70 years: results of the ALFA-9801 study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210

Title: The development of congestive heart failure and ventricular tachycardia after first exposure to idarubicin in a patient with acute myeloid leukaemia.

Journal: British journal of clinical pharmacology 20100201

Title: Updates on the treatment of acute promyelocytic leukemia.

Journal: Clinical advances in hematology & oncology : H&O 20100201

Title: [Tumor stem cells and their impact on the concept of cancer treatment].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100201

Title: Successful treatment of Hodgkin lymphoma and acute leukemia.

Journal: Leukemia & lymphoma 20100101

Title: Comparative analysis of remission induction therapy for high-risk MDS and AML progressed from MDS in the MDS200 study of Japan Adult Leukemia Study Group.

Journal: International journal of hematology 20100101

Title: Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea.

Journal: Journal of Korean medical science 20100101

Title: A case of acute colitis with severe rectal bleeding in a patient with chronic myeloid leukemia after dasatinib use.

Journal: Acta haematologica 20100101

Title: Fludarabine-induced bradycardia in a patient with refractory leukemia.

Journal: Annals of Saudi medicine 20100101

Title: Systemic mastocytosis associated with acute myeloid leukaemia.

Journal: Pathology 20100101

Title: Evaluation of the protective effects of quercetin, rutin, naringenin, resveratrol and trolox against idarubicin-induced DNA damage.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101

Title: Continuous infusion idarubicin and intravenous busulphan as conditioning regimen to autologous stem cell transplantation for patients with acute myeloid leukaemia.

Journal: Hematological oncology 20091201

Title: DV-ICE, intensive induction and early transplantation for adult patients with acute lymphoblastic leukemia: a phase II study.

Journal: European journal of haematology 20091201

Title: Uptake of anthracyclines in vitro and in vivo in acute myeloid leukemia cells in relation to apoptosis and clinical response.

Journal: European journal of clinical pharmacology 20091201

Title: [FLAG regimen as consolidation therapy for patients with acute myeloid leukemia].

Journal: Zhongguo shi yan xue ye xue za zhi 20091201

Title: A distinct subset of self-renewing human memory CD8+ T cells survives cytotoxic chemotherapy.

Journal: Immunity 20091120

Title: Daunorubicin versus mitoxantrone versus idarubicin as induction and consolidation chemotherapy for adults with acute myeloid leukemia: the EORTC and GIMEMA Groups Study AML-10.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091110

Title: Salvage therapy for acute myeloid leukemia with fludarabine, cytarabine, and idarubicin with or without gemtuzumab ozogamicin and with concurrent or sequential G-CSF.

Journal: American journal of hematology 20091101

Title: Mitoxantrone and etoposide in patients with newly diagnosed acute myeloid leukemia with persistent leukemia after a course of therapy with cytarabine and idarubicin.

Journal: Leukemia & lymphoma 20091101

Title: Vincristine, idarubicin, dexamethasone and thalidomide in scleromyxoedema.

Journal: Acta dermato-venereologica 20091101

Title: The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro.

Journal: Anticancer research 20091101

Title: Incidence and outcome of patients with diffuse large B cell lymphoma with marrow involvement and preliminary experience of an adult acute lymphoblastic leukemia protocol (NEALL VI) in cyclophosphamide, doxorubicin, vincristine, and prednisolone--rituximab refractory patients.

Journal: Leukemia & lymphoma 20091001

Title: Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001

Title: FLAIE (fludarabine, cytarabine, idarubicin, and etoposide), a four drug induction chemotherapy for adult acute myeloid leukemia: A single center experience.

Journal: American journal of hematology 20091001

Title: A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.

Journal: Acta pharmacologica Sinica 20091001

Title: [Standard therapies for acute myeloid leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001

Title: First reported case of aplastic anemia occurring in a patient after acute promyelocytic leukemia in remission.

Journal: Clinical advances in hematology & oncology : H&O 20091001

Title: Chronic myeloid leukemia (CML) with P190 BCR-ABL: analysis of characteristics, outcomes, and prognostic significance.

Journal: Blood 20090910

Title: Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090901

Title: Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2.

Journal: International journal of cancer 20090901

Title: Damage to the cell antioxidative system in human erythrocytes incubated with idarubicin and glutaraldehyde.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090901

Title: Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis.

Journal: Haematologica 20090901

Title: Twice daily fludarabine/Ara-C associated to idarubicin, G-CSF and ATRA is an effective salvage regimen in non-promyelocytic acute myeloid leukemia.

Journal: Leukemia research 20090801

Title: [Acute myeloid leukemia trials by Japan Adult Leukemia Study Group (JALSG)].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20090801

Title: An uncommon cause of small bowel obstruction: isolated primary granulocytic sarcoma.

Journal: QJM : monthly journal of the Association of Physicians 20090701

Title: Reappearance of acute myeloid leukemia after almost 23 years of continuous complete remission.

Journal: American journal of hematology 20090701

Title: The management of prolonged, isolated hyperbilirubinemia following cytarabine-based chemotherapy for acute myeloid leukaemia.

Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20090601

Title: [Klinefelter syndrome and acute myeloblastic leukaemia].

Journal: Presse medicale (Paris, France : 1983) 20090601

Title: DNA damage response as a biomarker in treatment of leukemias.

Journal: Cell cycle (Georgetown, Tex.) 20090601

Title: Additive effect of PTK787/ZK 222584, a potent inhibitor of VEGFR phosphorylation, with Idarubicin in the treatment of acute myeloid leukemia.

Journal: Experimental hematology 20090601

Title: The clinical outcome of FLAG chemotherapy without idarubicin in patients with relapsed or refractory acute myeloid leukemia.

Journal: Journal of Korean medical science 20090601

Title: Chromosomal aberration and micronucleus studies of two topoisomerase (II) targeting anthracyclines.

Journal: Journal of environmental biology 20090501

Title: The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia.

Journal: American journal of hematology 20090401

Title: [IDA-FLAG regimen in treatment of patients with refractory or relapsed acute leukemia].

Journal: Zhongguo shi yan xue ye xue za zhi 20090401

Title: Improvement of induction remission rate by modifying the dose of idarubicin for relapsed childhood acute lymphoblastic leukemia.

Journal: Journal of Korean medical science 20090401

Title: Development of idarubicin and doxorubicin solid lipid nanoparticles to overcome Pgp-mediated multiple drug resistance in leukemia.

Journal: Journal of biomedical nanotechnology 20090401

Title: Idarubicin inhibits the growth of bacteria and yeasts in an automated blood culture system.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20090301

Title: CTLA-4 genotype and relapse incidence in patients with acute myeloid leukemia in first complete remission after induction chemotherapy.

Journal: Leukemia 20090301

Title: Continuous infusion of intermediate-dose cytarabine and fludarabine with idarubicin for patients younger than 60 years with resistant acute myeloid leukemia: a prospective, multicenter phase II study.

Journal: American journal of hematology 20090301

Title: Autologous stem cell transplantation for elderly patients with acute myeloid leukaemia conditioned with continuous infusion idarubicin and busulphan.

Journal: Hematological oncology 20090301

Title: Biphenotypic acute leukemia treated with acute myeloid leukemia regimens: a case series.

Journal: Journal of the National Medical Association 20090301

Title: Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells.

Journal: Leukemia research 20090201

Title: Loss of enterocyte mass is accompanied by diminished turnover of enterocytes after myeloablative therapy in haematopoietic stem-cell transplant recipients.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20090201

Title: Fluorescence anisotropy of membrane fluidity probes in human erythrocytes incubated with anthracyclines and glutaraldehyde.

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20090201

Title: [Standard-dose of idarubicin in combination with continuous infusion of cytarabine as induction therapy in patients with acute myeloid leukaemia].

Journal: Zhongguo shi yan xue ye xue za zhi 20090201

Title: TRAIL-induced apoptosis of HL60 leukemia cells: two distinct phenotypes of acquired TRAIL resistance that are accompanied with resistance to TNFalpha but not to idarubicin and cytarabine.

Journal: Blood cells, molecules & diseases 20090101

Title: Acute promyelocytic leukemia in early pregnancy with translocation t(15;17) and variant PML/RARA fusion transcripts.

Journal: Cancer genetics and cytogenetics 20090101

Title: Persistent hiccups as an adverse event to FLAG-IDA regimen for leukemia.

Journal: Acta oncologica (Stockholm, Sweden) 20090101

Title: Acute promyelocytic leukemia after whole brain irradiation of primary brain lymphoma in an HIV-infected patient.

Journal: European journal of medical research 20090101

Title: Pure erythroid leukemia with hemophagocytosis.

Journal: Internal medicine (Tokyo, Japan) 20090101

Title: Successful treatment of hepatic encephalopathy in a patient with acute lymphoblastic leukemia.

Journal: Acta haematologica 20090101

Title: Gemtuzumab-ozogamicin in combination with fludarabine, cytarabine, idarubicin (FLAI-GO) as induction therapy in CD33-positive AML patients younger than 65 years.

Journal: Leukemia research 20081201

Title: Risk factors and decision criteria for intensive chemotherapy in older patients with acute myeloid leukemia.

Journal: Haematologica 20081201

Title: Triptolide cooperates with chemotherapy to induce apoptosis in acute myeloid leukemia cells.

Journal: Experimental hematology 20081201

Title: Treatment of core-binding-factor in acute myelogenous leukemia with fludarabine, cytarabine, and granulocyte colony-stimulating factor results in improved event-free survival.

Journal: Cancer 20081201

Title: Clinical and biological features of acute promyelocytic leukemia patients developing retinoic acid syndrome during induction treatment with all-trans retinoic acid and idarubicin.

Journal: Haematologica 20081201

Title: Human leukocyte antigen-DR negative de novo acute myeloid leukemia with Philadelphia chromosome.

Journal: International journal of hematology 20081201

Title: Outcome of high-dose cytarabine-based induction therapy followed by hematopoietic stem cell transplantation in acute myeloid leukemia: influence of karyotype.

Journal: Leukemia & lymphoma 20081201

Title: Granulocytic sarcoma of the right humerus in a non-leukaemia patient.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20081101

Title: [Granulocytic sarcoma of the prostate presenting with urinary obstruction which progressed to acute myeloid leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20081101

Title: Life-threatening conjunctival presentation of myeloid sarcoma.

Journal: Clinical & experimental ophthalmology 20081101

Title: Clofarabine combinations as acute myeloid leukemia salvage therapy.

Journal: Cancer 20081015

Title: Thrombosis of the cerebral veins and sinuses in acute promyelocytic leukemia after all-trans retinoic acid treatment: a case report.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20081001

Title: Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia.

Journal: Cancer 20080915

Title: Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan.

Journal: International journal of hematology 20080901

Title: Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected].

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080820

Title: Reduced uptake of liposomal idarubicin in the perfused rat heart.

Journal: Anti-cancer drugs 20080801

Title: Neutrophilic dermatoses with acute myeloid leukemia associated with an increase of serum colony-stimulating factor.

Journal: Journal of the American Academy of Dermatology 20080801

Title: [Loeys-Dietz syndrome with acute myeloid leukemia].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20080801

Title: Upregulation of topoisomerase IIalpha expression in advanced gallbladder carcinoma: a potential chemotherapeutic target.

Journal: Journal of cancer research and clinical oncology 20080701

Title: Acute myeloid leukemia in the elderly: conventional and novel treatment approaches.

Journal: Blood reviews 20080701

Title: Pseudotumor cerebri as a reversible side effect of all-trans retinoic acid treatment in acute promyelocytic leukaemia.

Journal: European journal of neurology 20080701

Title: Acute myeloid leukaemia presenting as recurrent generalized urticaria in infancy.

Journal: European journal of pediatrics 20080601

Title: Aberrant phenotype of plasmacytoid monocytes in acute myeloid leukemia.

Journal: American journal of hematology 20080501

Title: Adenovirus-mediated PDCD5 gene transfer sensitizes K562 cells to apoptosis induced by idarubicin in vitro and in vivo.

Journal: Apoptosis : an international journal on programmed cell death 20080501

Title: Granulocytic sarcoma with massive scalp involvement.

Journal: American journal of hematology 20080401

Title: Association of 3q21q26 syndrome and late-appearing Philadelphia chromosome in acute myeloid leukemia.

Journal: Leukemia 20080401

Title: Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin.

Journal: Blood 20080401

Title: Treatment of children with metastatic soft tissue sarcoma with oral maintenance compared to high dose chemotherapy: report of the HD CWS-96 trial.

Journal: Pediatric blood & cancer 20080401

Title: Alleviation of the drug-resistant phenotype in idarubicin and cytosine arabinoside double-resistant acute myeloid leukemia cells by indomethacin.

Journal: International journal of oncology 20080401

Title: Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells.

Journal: Leukemia & lymphoma 20080401

Title: Pharmacokinetic self-potentiation of idarubicin by induction of anthracycline carbonyl reducing enzymes.

Journal: Leukemia & lymphoma 20080401

Title: Pseudo-Gaucher cells in multiple myeloma.

Journal: International journal of surgical pathology 20080401

Title: Acute monoblastic leukemia with t(10;11)(p12;q23) presenting with pulmonary involvement: a case report and literature review.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080401

Title: Modified IDARAM chemotherapy regimen for primary central nervous system lymphoma: experience of three cases.

Journal: Hematology (Amsterdam, Netherlands) 20080401

Title: [3,3-diindolylmethane enhances the inhibitory effect of idarubicin on the growth of human prostate cancer cells].

Journal: Zhonghua yi xue za zhi 20080311

Title: Complex chromosome 8;21 translocation with associated hyperdiploidy in acute myeloid leukemia (FAB-M2).

Journal: Pediatric blood & cancer 20080301

Title: Long-term propylthiouracil use and acute myeloid leukemia: a case report and review of the literature.

Journal: Annals of hematology 20080301

Title: Clinical outcome of children with newly diagnosed acute lymphoblastic leukemia treated in a single center in Shanghai, China.

Journal: Leukemia & lymphoma 20080301

Title: Drug-induced hypersensitivity syndrome with rapid hematopoietic reconstitution during treatment for acute myeloid leukemia.

Journal: Haematologica 20080301

Title: Phase I and pharmacokinetic study of bortezomib in combination with idarubicin and cytarabine in patients with acute myelogenous leukemia.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080301

Title: Two possible cases of Trichosporon infections in bone-marrow-transplanted children: the first case of T. japonicum isolated from clinical specimens.

Journal: Japanese journal of infectious diseases 20080301

Title: Amifostine can differentially modulate DNA double-strand breaks and apoptosis induced by idarubicin in normal and cancer cells.

Journal: Experimental oncology 20080301

Title: Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the children's oncology group.

Journal: Blood 20080201

Title: Significance of age in acute myeloid leukemia patients younger than 30 years: a common analysis of the pediatric trials AML-BFM 93/98 and the adult trials AMLCG 92/99 and AMLSG HD93/98A.

Journal: Cancer 20080201

Title: Central nervous system relapse occurs in about 5% of cases of acute promyelocytic leukaemia.

Journal: Haematologica 20080201

Title: Translocation (2;11)(q37;q23) in therapy-related myelodysplastic syndrome after treatment for acute promyelocytic leukemia.

Journal: Cancer genetics and cytogenetics 20080115

Title: The induction of apoptosis by daunorubicin and idarubicin in human trisomic and diabetic fibroblasts.

Journal: Cellular & molecular biology letters 20080101

Title: A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-to-intermediate risk acute myeloid leukemia: results from a randomized, double-blind, phase 2 trial.

Journal: BMC cancer 20080101

Title: Bioreduction of idarubicin and formation of ROS responsible for DNA cleavage by NADPH-cytochrome P450 reductase and its potential role in the antitumor effect.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101

Title: Two cases of isolated symptomatic myocarditis induced by all-trans retinoic acid (ATRA).

Journal: Annals of hematology 20071201

Title: The PRKAR1A gene is fused to RARA in a new variant acute promyelocytic leukemia.

Journal: Blood 20071201

Title: A comparison of the effect of anticancer drugs, idarubicin and adriamycin, on soluble chromatin.

Journal: European journal of pharmacology 20071201

Title: A randomized comparison of immediate versus delayed application of G-CSF in induction therapy for patients with acute myeloid leukemia unfit for intensive chemotherapy.

Journal: Haematologica 20071201

Title: Myeloid sarcoma presenting in muscle-tissue of the lower limb: unusual origin of a compartment-syndrome.

Journal: American journal of clinical oncology 20071201

Title: Repair of idarubicin-induced DNA damage: a cause of resistance?

Journal: DNA repair 20071101

Title: [A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20071101

Title: Itraconazole-enhanced vindesine neurotoxicity in adult acute lymphoblastic leukaemia.

Journal: American journal of hematology 20071001

Title: Adding lomustine to idarubicin and cytarabine for induction chemotherapy in older patients with acute myeloid leukemia: the BGMT 95 trial results.

Journal: Haematologica 20071001

Title: Could ATRA/Idarubicin treatment of acute promyelocytic leukemia induce the appearance of new clonal cytogenetic abnormalities in patients in complete remission?

Journal: Leukemia research 20070901

Title: A new intensive induction schedule, including high-dose Idarubicin, high-dose Aracytin and Amifostine, in older AML patients: feasibility and long-term results in 42 patients.

Journal: Experimental hematology 20070701

Title: Adding low-dose gemtuzumab ozogamicin to fludarabine, Ara-C and idarubicin (MY-FLAI) may improve disease-free and overall survival in elderly patients with non-M3 acute myeloid leukaemia: results of a prospective, pilot, multi-centre trial and comparison with a historical cohort of patients.

Journal: British journal of haematology 20070701

Title: Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial.

Journal: Blood 20070615

Title: High-dose idarubicin in combination with Ara-C in patients with relapsed or refractory acute lymphoblastic leukemia: a pharmacokinetic and clinical study.

Journal: Cancer chemotherapy and pharmacology 20070501

Title: Divergent cytotoxic effects of PKC412 in combination with conventional antileukemic agents in FLT3 mutation-positive versus -negative leukemia cell lines.

Journal: Leukemia 20070501

Title: Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow.

Journal: Haematologica 20070501

Title: The combined effect of IDA and glutaraldehyde on the erythrocyte membrane proteins.

Journal: International journal of pharmaceutics 20070420

Title: Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia.

Journal: Pediatric blood & cancer 20070401

Title: Neutrophilic eccrine hidradenitis masquerading as facial cellulitis.

Journal: Journal of the American Academy of Dermatology 20070401

Title: Traces of phosgene in chloroform: consequences for extraction of anthracyclines.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

Title: Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to idarubicin + high-dose Ara-C: a phase 1 study.

Journal: Blood 20070401

Title: Proteasome inhibition specifically sensitizes leukemic cells to anthracyclin-induced apoptosis through the accumulation of Bim and Bax pro-apoptotic proteins.

Journal: Cancer biology & therapy 20070401

Title: Acute cardiac functional and morphological changes after Anthracycline infusions in children.

Journal: The American journal of cardiology 20070401

Title: [Acute promyelocytic leukemia associated with hemophagocytic syndrome].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20070401

Title: Trilateral retinoblastoma.

Journal: Pediatric blood & cancer 20070301

Title: Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention.

Journal: Leukemia 20070301

Title: Levels of soluble HLA-I and beta2M in patients with acute myeloid leukemia and advanced myelodysplastic syndrome: association with clinical behavior and outcome of induction therapy.

Journal: Leukemia 20070301

Title: Using quantification of the PML-RARalpha transcript to stratify the risk of relapse in patients with acute promyelocytic leukemia.

Journal: Haematologica 20070301

Title: Autologous stem cell transplantation after complete remission and first consolidation in acute myeloid leukemia patients aged 61-70 years: results of the prospective EORTC-GIMEMA AML-13 study.

Journal: Haematologica 20070301

Title: The haematopoietic cell transplantation comorbidity index score is predictive of early death and survival in patients over 60 years of age receiving induction therapy for acute myeloid leukaemia.

Journal: British journal of haematology 20070201

Title: A pilot study of imatinib, low-dose cytarabine and idarubicin for patients with chronic myeloid leukemia in myeloid blast phase.

Journal: Leukemia & lymphoma 20070201

Title: Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features.

Journal: Leukemia 20070101

Title: Acute myeloid leukemia with T-cell receptor gamma gene rearrangement occurring in a patient with chronic lymphocytic leukemia: a case report.

Journal: American journal of hematology 20070101

Title: Preclinical assessment of anthracycline cardiotoxicity in laboratory animals: predictiveness and pitfalls.

Journal: Cell biology and toxicology 20070101

Title: Late relapses in acute promyelocytic leukaemia.

Journal: Acta haematologica 20070101

Title: Pilot remission induction therapy with idarubicin, plus an intensified dose of ara-C and priming with granulocyte colony-stimulating factor for acute myeloid leukemia.

Journal: Acta haematologica 20070101

Title: Multiple complete remissions over a period of 6 years in a patient with acute myeloid leukemia after intensive chemotherapy.

Journal: Leukemia & lymphoma 20070101

Title: Pilot study of gemtuzumab ozogamicin (GO), fludarabine, cytarabine and idarubicin combined regimen (GO-FLAI) as first-line induction therapy plus GO alone as consolidation therapy for elderly acute myeloid leukemia patients.

Journal: Acta haematologica 20070101

Title: Anthracycline antibiotics induce acute renal tubular toxicity in children with cancer.

Journal: Pathology oncology research : POR 20070101

Title: Early imatinib-mesylate-induced hepatotoxicity in chronic myelogenous leukaemia.

Journal: Acta haematologica 20070101

Title: Anthracycline glycosides of 2,6-dideoxy-2-fluoro-alpha-L-talopyranose.

Journal: Carbohydrate research 20061127

Title: Clinical response of cutaneous squamous-cell carcinoma to bortezomib given for myeloma.

Journal: The Lancet. Oncology 20061101

Title: The addition of oral idarubicin to a chlorambucil/dexamethasone combination has a significant impact on time to treatment failure but none on overall survival in patients with low grade non-Hodgkin's lymphoma: Results of the Scotland and Newcastle Lymphoma Group randomized NHL VIII trial.

Journal: Leukemia & lymphoma 20061101

Title: Relapse of acute promyelocytic leukemia presenting as granulocytic sarcoma in the hip.

Journal: Annals of hematology 20061001

Title: Non-infusional vs intravenous consolidation chemotherapy in elderly patients with acute myeloid leukemia: final results of the EORTC-GIMEMA AML-13 randomized phase III trial.

Journal: Leukemia 20061001

Title: [Bulky lymphadenopathy in acute myeloid leukemia with inv (16) (p13q22): a case report].

Journal: Zhongguo shi yan xue ye xue za zhi 20061001

Title: Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060920

Title: Comparative study of DNA damage, cell cycle and apoptosis in human K562 and CCRF-CEM leukemia cells: role of BCR/ABL in therapeutic resistance.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060901

Title: [Multicenter randomized control trial on safety of domestic idarubicin for acute leukemia].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20060901

Title: Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor.

Journal: Blood 20060815

Title: Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells.

Journal: Leukemia research 20060701

Title: Clearance of leukaemic blasts from peripheral blood during standard induction treatment predicts the bone marrow response in acute myeloid leukaemia: a pilot study.

Journal: British journal of haematology 20060701

Title: Myeloid sarcoma of the urinary bladder and epididymis as a primary manifestation of acute myeloid leukemia with inv(16).

Journal: Archives of pathology & laboratory medicine 20060601

Title: Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series.

Journal: Leukemia & lymphoma 20060601

Title: t(8;16) AML developed subsequent to breast cancer therapy.

Journal: Hematology (Amsterdam, Netherlands) 20060601

Title: MATILDE regimen followed by radiotherapy is an active strategy against primary CNS lymphomas.

Journal: Neurology 20060509

Title: Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20060501

Title: Remission induction chemotherapy induces in vivo caspase-dependent apoptosis in bone marrow acute myeloid leukemia blast cells and spares lymphocytes.

Journal: Cytometry. Part B, Clinical cytometry 20060501

Title: The significance of minimal residual disease kinetics in adults with newly diagnosed PML-RARalpha-positive acute promyelocytic leukemia: results of a prospective trial.

Journal: Haematologica 20060501

Title: Addition of cyclosporin-A to chemotherapy in secondary (post-MDS) AML in the elderly. A multicenter randomized trial of the Leukemia Working Group of the Hellenic Society of Hematology.

Journal: Annals of hematology 20060401

Title: Intensive consolidation versus oral maintenance therapy in patients 61 years or older with acute myeloid leukemia in first remission: results of second randomization of the AML HD98-B treatment Trial.

Journal: Leukemia 20060401

Title: Sequential response-adapted induction and consolidation regimens idarubicin/cytarabine and mitoxantrone/etoposide in adult acute myelogenous leukemia: 10 year follow-up of a study by the Canadian Leukemia Studies Group.

Journal: Leukemia & lymphoma 20060401

Title: Bilateral ear Sweet's syndrome in a case with relapse acute myeloblastic leukemia.

Journal: Leukemia research 20060301

Title: Long-term follow-up results of the combination of topotecan and cytarabine and other intensive chemotherapy regimens in myelodysplastic syndrome.

Journal: Cancer 20060301

Title: The length of treatment of aggressive non-Hodgkin's lymphomas established according to the international prognostic index score: long-term results of the GISL LA03 study.

Journal: European journal of haematology 20060301

Title: Interaction of doxorubicin and idarubicin with red blood cells from acute myeloid leukaemia patients.

Journal: Cell biology international 20060201

Title: Subacute anthracycline cardiotoxicity.

Journal: Heart, lung & circulation 20060201

Title: Multidrug reverting activity toward leukemia cells in a group of new verapamil analogues with low cardiovascular activity.

Journal: Leukemia research 20060101

Title: Feasibility of FLAG-IDA regimen in cases with relapsed/refractory acute leukemia cases.

Journal: Annals of hematology 20060101

Title: Effects of idarubicin and idarubicinol on rat coronary resistance and vasoconstrictor responsiveness of isolated aorta and mesentery.

Journal: Anti-cancer drugs 20060101

Title: High-dose idarubicin, busulphan and melphalan for autologous stem cell transplantation in multiple myeloma responsive to DAV chemotherapy: comparison with a historical control.

Journal: Acta haematologica 20060101

Title: Secondary leukemia after treatment with paclitaxel and carboplatin in a patient with recurrent ovarian cancer.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101

Title: Nickel(II) affects poly(ADP-ribose) polymerase-mediated DNA repair in normal and cancer cells.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101

Title: Donor cell leukemia developing after hematopoietic stem cell transplantation for multiple myeloma.

Journal: Acta clinica Belgica 20060101

Title: AmBisome treatment of fungal sinusitis in severe immunocompromised patient with acute lymphoblastic leukemia relapsed after autologous peripheral blood transplantation.

Journal: Acta bio-medica : Atenei Parmensis 20060101

Title: IDA-FLAG regimen for the therapy of primary refractory and relapse acute leukemia: a single-center experience.

Journal: American journal of therapeutics 20060101

Title: Pseudomembranous necrotizing tracheobronchitis caused by Aspergillus spp--contribution of one case with acute myeloid leukemia.

Journal: Folia medica 20060101

Title: A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult Leukemia Study Group AML 97 Study.

Journal: Cancer 20051215

Title: Twenty years of Polish experience with three consecutive protocols for treatment of childhood acute myelogenous leukemia.

Journal: Leukemia 20051201

Title: Results of 58872 and 58921 trials in acute myeloblastic leukemia and relative value of chemotherapy vs allogeneic bone marrow transplantation in first complete remission: the EORTC Children Leukemia Group report.

Journal: Leukemia 20051201

Title: Acute myeloid leukemia with near-triploid karyotype and extramedullary involvement of mediastinum.

Journal: Bone marrow transplantation 20051201

Title: TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease.

Journal: Leukemia & lymphoma 20051201

Title: The prognostic value of MLL-AF9 detection in patients with t(9;11)(p22;q23)-positive acute myeloid leukemia.

Journal: Haematologica 20051201

Title: Amsacrine combined with etoposide and high-dose methylprednisolone as salvage therapy in acute lymphoblastic leukemia in children.

Journal: Haematologica 20051201

Title: All-trans retinoic acid-induced myositis.

Journal: British journal of haematology 20051201

Title: Posterior leukoencephalopathy after combination chemotherapy in a patient with lymphoma.

Journal: Leukemia & lymphoma 20051201

Title: Idarubicin and idarubicinol effects on breast cancer multicellular spheroids.

Journal: Journal of chemotherapy (Florence, Italy) 20051201

Title: Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin B.

Journal: Haematologica 20051201

Title: [Multi-institutional randomized controlled clinical trial on China made 4-demethoxydaunokrubicin (IDA) in the treatment of acute leukemia].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20051201

Title: The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene.

Journal: Oncogene 20051103

Title: FLAG-IDA in the treatment of refractory/relapsed adult acute lymphoblastic leukemia.

Journal: Annals of hematology 20051101

Title: Treatment with all-trans retinoic acid and anthracycline monochemotherapy for children with acute promyelocytic leukemia: a multicenter study by the PETHEMA Group.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020

Title: Multicentre phase III trial on fludarabine, cytarabine (Ara-C), and idarubicin versus idarubicin, Ara-C and etoposide for induction treatment of younger, newly diagnosed acute myeloid leukaemia patients.

Journal: British journal of haematology 20051001

Title: Medical ethics collides with public policy: LVAD for a patient with leukemia.

Journal: The Annals of thoracic surgery 20050901

Title: Ifosfamide, idarubicin, and etoposide in relapsed/refractory Hodgkin disease or non-Hodgkin lymphoma: a salvage regimen with high response rates before autologous stem cell transplantation.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050901

Title: Use of MLL/GRAF fusion mRNA for measurement of minimal residual disease during chemotherapy in an infant with acute monoblastic leukemia (AML-M5).

Journal: Genes, chromosomes & cancer 20050801

Title: Acute megakaryoblastic leukemia in children and adolescents, excluding Down's syndrome: improved outcome with intensified induction treatment.

Journal: Leukemia 20050801

Title: AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity.

Journal: Leukemia 20050801

Title: Comparison of CHOP versus CIOP in good prognosis younger patients with histologically aggressive non-Hodgkin lymphoma.

Journal: British journal of haematology 20050801

Title: High-dose idarubicin, cyclophosphamide and melphalan as conditioning for autologous stem cell transplantation increases treatment-related mortality in patients with multiple myeloma: results of a randomised study.

Journal: British journal of haematology 20050801

Title: GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children.

Journal: Blood 20050715

Title: Treatment of relapsed acute lymphoblastic leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a prospective study.

Journal: Bone marrow transplantation 20050701

Title: Substantial increases in idarubicin plasma concentration by liposome encapsulation mediates improved antitumor activity.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050620

Title: High-dose cytarabine and mitoxantrone in consolidation therapy for acute promyelocytic leukemia.

Journal: Leukemia 20050601

Title: Trying to improve clinical outcome in AML: lessons from negative trials.

Journal: Leukemia research 20050601

Title: Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes.

Journal: Leukemia research 20050601

Title: IIVP salvage regimen induces high response rates in patients with relapsed lymphoma before autologous stem cell transplantation.

Journal: American journal of clinical oncology 20050601

Title: FLAG-IDA in the treatment of refractory/relapsed acute leukaemias: single centre study.

Journal: JPMA. The Journal of the Pakistan Medical Association 20050601

Title: A comparison of the action of amifostine and melatonin on DNA-damaging effects and apoptosis induced by idarubicin in normal and cancer cells.

Journal: Journal of pineal research 20050501

Title: A phase I/II study of oral etoposide and idarubicin in elderly patients with high-risk acute myeloid leukemia unable to undergo intensive chemotherapy.

Journal: Annals of hematology 20050401

Title: Mini-ICE effectively mobilises peripheral blood stem cells after fludarabine-based regimens in acute myeloid leukaemia.

Journal: European journal of haematology 20050401

Title: Prospective evaluation of gut mucosal barrier injury following various myeloablative regimens for haematopoietic stem cell transplant.

Journal: Bone marrow transplantation 20050401

Title: A phase I and pharmacologic study of idarubicin, cytarabine, etoposide, and the multidrug resistance protein (MDR1/Pgp) inhibitor PSC-833 in patients with refractory leukemia.

Journal: Leukemia research 20050301

Title: Toxicity of the topoisomerase II inhibitors.

Journal: Expert opinion on drug safety 20050301

Title: Anti-CD33 monoclonal antibodies enhance the cytotoxic effects of cytosine arabinoside and idarubicin on acute myeloid leukemia cells through similarities in their signaling pathways.

Journal: Experimental hematology 20050201

Title: Acute pancreatitis during all-trans-retinoic acid treatment for acute promyelocytic leukemia in a patient without overt hypertriglyceridemia.

Journal: Japanese journal of clinical oncology 20050201

Title: A randomized trial of high-versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine.

Journal: Blood 20050115

Title: High-dose idarubicin and busulphan as conditioning to autologous stem cell transplantation in adult patients with acute myeloid leukaemia.

Journal: British journal of haematology 20050101

Title: Outcome of acute myeloid leukaemia in adults: a retrospective analysis.

Journal: The National medical journal of India 20050101

Title: Phase II study of an 'all-oral' regimen of capecitabine, idarubicin and cyclophosphamide for metastatic breast cancer--safety, efficacy and quality of life.

Journal: Oncology 20050101

Title: The use of biochemical markers in cardiotoxicity monitoring in patients treated for leukemia.

Journal: Neoplasma 20050101

Title: Stem cell transplantation as consolidation therapy for children in first-remission AML: a single-center report.

Journal: Pediatric hematology and oncology 20050101

Title: Reticulate Hyperpigmentation secondary to 5-fluorouracil and idarubicin.

Journal: Journal of drugs in dermatology : JDD 20050101

Title: All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia.

Journal: Blood 20041201

Title: VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia.

Journal: European journal of haematology 20041201

Title: Resistant pure red cell aplasia after allogeneic stem cell transplantation with major ABO mismatch treated by escalating dose donor leukocyte infusion.

Journal: European journal of haematology 20041201

Title: Complex t(8;14;21)(q22;q13;q22), a variant of t(8;21), with t(15;21)(q15;p11) in a patient with acute myelogenous leukemia (M1).

Journal: Cancer genetics and cytogenetics 20041201

Title: Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041201

Title: Cytoprotection in acute myelogenous leukemia (AML) therapy.

Journal: Seminars in oncology 20041201

Title: Phase III study of all-trans retinoic acid in previously untreated patients 61 years or older with acute myeloid leukemia.

Journal: Leukemia 20041101

Title: Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience.

Journal: American journal of hematology 20041101

Title: Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041101

Title: Continuous infusion idarubicin and oral busulfan as conditioning for patients with acute myeloid leukemia aged over 60 years undergoing autologous stem cell transplantation.

Journal: Bone marrow transplantation 20041001

Title: Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.

Journal: Pediatric blood & cancer 20041001

Title: Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.

Journal: British journal of haematology 20041001

Title: [Pseudomonas sepsis with ecthyma gangrenosum in an acute myeloid leukemia patient].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20041001

Title: Idarubicin and standard-dose cytosine arabinoside in adults with recurrent and refractory acute lymphocytic leukemia.

Journal: Cancer 20040915

Title: Pressure-induced bullae and sweat gland necrosis following chemotherapy induction.

Journal: The American journal of medicine 20040915

Title: Mutational analysis of P-glycoprotein: suppression of caspase activation in the absence of ATP-dependent drug efflux.

Journal: Cell death and differentiation 20040901

Title: Effectiveness of fludarabine, idarubicin and cyclophosphamide (FLUIC) combination regimen for young patients with untreated non-follicular low-grade non-Hodgkin's lymphoma.

Journal: Leukemia & lymphoma 20040901

Title: A randomized study (WOS MM1) comparing the oral regime Z-Dex (idarubicin and dexamethasone) with vincristine, adriamycin and dexamethasone as induction therapy for newly diagnosed patients with multiple myeloma.

Journal: British journal of haematology 20040901

Title: Aggressive systemic mastocytosis mimicking sclerosing cholangitis.

Journal: Haematologica 20040901

Title: A single-center, retrospective study of management and outcome of 45 elderly AML patients, diagnosed in 2001.

Journal: Journal of experimental & clinical cancer research : CR 20040901

Title: Thiol oxidation induced by oxidative action of adriamycin.

Journal: Free radical research 20040901

Title: Intensive chemotherapy with idarubicin, cytarabine, etoposide, and G-CSF priming in patients with advanced myelodysplastic syndrome and high-risk acute myeloid leukemia.

Journal: Annals of hematology 20040801

Title: MPA inhibits idarubicin activity on Cu-Zn SOD and catalase.

Journal: Veterinary research communications 20040801

Title: Development of leukocytoclastic vasculitis in a patient with multiple myeloma during treatment with thalidomide.

Journal: Annals of hematology 20040701

Title: Late relapse of acute promyelocytic leukemia treated with all- trans retinoic acid and chemotherapy: report of two cases.

Journal: Annals of hematology 20040701

Title: Chemotherapy during pregnancy: what is really safe?

Journal: The Lancet. Oncology 20040701

Title: Feasibility and results of autologous stem cell transplantation in de novo acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocol.

Journal: Haematologica 20040701

Title: Risk-adapted induction and consolidation therapy in adults with de novo AML aged </= 60 years: results of a prospective multicenter trial.

Journal: Annals of hematology 20040601

Title: Treatment of acute leukemia with idarubicin, etoposide and cytarabine (IDEA). A randomized study of etoposide schedule.

Journal: Cancer chemotherapy and pharmacology 20040601

Title: Enantioselective synthesis of (+)-8-hydroxy-8-methylidarubicinone.

Journal: Bioorganic & medicinal chemistry 20040601

Title: In vitro evaluation of cytochrome P450-mediated drug interactions between cytarabine, idarubicin, itraconazole and caspofungin.

Journal: Hematology (Amsterdam, Netherlands) 20040601

Title: Nuclear factor-kappaB mediates up-regulation of cathepsin B by doxorubicin in tumor cells.

Journal: Molecular pharmacology 20040501

Title: A case of T-cell acute lymphoblastic leukemia after treatment of acute promyelocytic leukemia.

Journal: International journal of hematology 20040501

Title: The development of targeted chemotherapy for CNS lymphoma-a pilot study of the IDARAM regimen.

Journal: Cancer chemotherapy and pharmacology 20040401

Title: Measuring mucosal damage induced by cytotoxic therapy.

Journal: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20040401

Title: [Effects of leukemia bone marrow stromal cells on resistance of co-cultured HL-60 to idarubicin].

Journal: Zhongguo shi yan xue ye xue za zhi 20040401

Title: Pharmacokinetic comparison of 120-hour infusion versus hyperfractionated oral administration of idarubicin.

Journal: Journal of chemotherapy (Florence, Italy) 20040401

Title: Oral idarubicin, dexamethasone and vincristine in the treatment of multiple myeloma: final analysis of a phase II trial.

Journal: Haematologica 20040301

Title: Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: a multicenter study by the PETHEMA group.

Journal: Blood 20040215

Title: Results of a prospective study for the treatment of retinoblastoma.

Journal: Cancer 20040215

Title: Protein 4.1 deficiency and deletion of chromosome 20q are associated with acquired elliptocytosis in myelodysplastic syndrome.

Journal: Clinical and laboratory haematology 20040201

Title: Unexpected toxicities in elderly patients treated with oral idarubicin in metastatic breast cancer: the GINECO experience.

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20040201

Title: New oral drugs in older patients: a review of idarubicin in elderly patients.

Journal: Critical reviews in oncology/hematology 20040201

Title: Increased myelotoxicity of idarubicin: is there a pharmacological basis? Results of a pharmacokinetic and an in vitro cytotoxicity study.

Journal: Cancer chemotherapy and pharmacology 20040101

Title: Fludarabine, cytosine arabinoside, granulocyte-colony stimulating factor with or without idarubicin in the treatment of high risk acute leukaemia or myelodysplastic syndromes.

Journal: British journal of haematology 20040101

Title: Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040101

Title: Clinico-biological features and outcome of acute promyelocytic leukemia patients with persistent polymerase chain reaction-detectable disease after the AIDA front-line induction and consolidation therapy.

Journal: Haematologica 20040101

Title: Oral treatment of acute myeloid leukaemia with etoposide, thioguanine, and idarubicin (ETI) in elderly patients: a prospective randomised comparison with intravenous cytarabine, idarubicin, and thioguanine in the second and third treatment cycle.

Journal: European journal of haematology 20040101

Title: Ida-FLAG plus imatinib mesylate-induced molecular remission in a patient with chemoresistant Ph1+ acute myeloid leukemia.

Journal: European journal of haematology 20040101

Title: Acute promyelocytic leukemia during pregnancy: report of 3 cases.

Journal: International journal of hematology 20040101

Title: Hemopoietic recovery and infectious complications in breast cancer and multiple myeloma after autologous CD34+ cell-selected peripheral blood progenitor cell transplantation.

Journal: International journal of hematology 20040101

Title: Successful treatment with nonmyeloablative allogeneic hematopoietic stem cell transplantation in a patient with acute myeloid leukemia complicated with pulmonary infection.

Journal: International journal of hematology 20040101

Title: ABL-fusion oncoproteins activate multi-pathway of DNA repair: role in drug resistance?

Journal: Biochimie 20040101

Title: Acute myeloblastic leukemia in pregnancy: a case report and review of the literature.

Journal: European journal of gynaecological oncology 20040101

Title: The results of treatment with idarubicin in childhood acute nonlymphoblastic leukemia.

Journal: The Turkish journal of pediatrics 20040101

Title: Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila Somatic Mutation and Recombination Test.

Journal: Environmental and molecular mutagenesis 20040101

Title: Idarubicin administered during pregnancy: its effects on the fetus.

Journal: Gynecologic and obstetric investigation 20040101

Title: Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy.

Journal: Anticancer research 20040101

Title: Efficacy of granulocyte and granulocyte-macrophage colony-stimulating factors in the induction treatment of adult acute lymphoblastic leukemia: a multicenter randomized study.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: Primary central nervous system lymphoma (PCNSL) in immunocompetent adults: analysis of a retrospective series of patients treated using idarubicin-containing regimen and radiotherapy.

Journal: The hematology journal : the official journal of the European Haematology Association 20040101

Title: A feasibility study of simultaneous administration of gemtuzumab ozogamicin with intensive chemotherapy in induction and consolidation in younger patients with acute myeloid leukemia.

Journal: Blood 20031215

Title: Dexrazoxane's protection of jejunal crypt cells in the jejunum of C3Hf/Kam mice from doxorubicin-induced toxicity.

Journal: Cancer chemotherapy and pharmacology 20031201

Title: In vitro antileukemic effect of a new anthracycline analogue, MEN 11079.

Journal: Leukemia research 20031201

Title: High dose of idarubicin-based regimen for diffuse large cell AIDS-related non-Hodgkin's lymphoma with or without antiretroviral therapy during antineoplastic agents.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20031201

Title: Increased remissions from one course for intermediate-dose cytosine arabinoside and idarubicin in elderly acute myeloid leukaemia when combined with cladribine. A randomized population-based phase II study.

Journal: British journal of haematology 20031201

Title: Adult T-biphenotypic acute leukaemia: clinical and biological features and outcome.

Journal: British journal of haematology 20031201

Title: More efficient mobilisation of peripheral blood stem cells with HiDAC+AMSA+G-CSF than with mini-ICE+G-CSF in patients with AML.

Journal: Bone marrow transplantation 20031201

Title: Low dose gemtuzumab ozogamicin for relapsed acute myeloid leukaemia in elderly.

Journal: Haematologica 20031201

Title: MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.

Journal: International journal of hematology 20031201

Title: Apoptosis induction in peripheral leukemia cells by remission induction treatment in vivo: selective depletion and apoptosis in a CD34+ subpopulation of leukemia cells.

Journal: Leukemia 20031101

Title: Pretransplant minimal residual disease level predicts clinical outcome in patients with acute myeloid leukemia receiving high-dose chemotherapy and autologous stem cell transplantation.

Journal: Leukemia 20031101

Title: [Acute myelogenous leukemia complicated with severe tumor lysis syndrome after a single day of idarubicin/cytarabine chemotherapy].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20031101

Title: FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.

Journal: Blood 20031001

Title: Phase 2 study of idarubicin in pediatric brain tumors: Pediatric Oncology Group study POG 9237.

Journal: Neuro-oncology 20031001

Title: [Intensive multi-drug chemotherapy for acute myeloid leukemia in a renal allograft recipient].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20031001

Title: Inhibition of membrane-associated calcium-independent phospholipase A2 as a potential culprit of anthracycline cardiotoxicity.

Journal: Cancer research 20030915

Title: Primary central nervous system lymphoma: Phase I evaluation of infusional bromodeoxyuridine with whole brain accelerated fractionation radiation therapy after chemotherapy.

Journal: Cancer 20030901

Title: TEL-fusion oncogenic tyrosine kinases determine leukemic cells response to idarubicin.

Journal: Anti-cancer drugs 20030901

Title: Medroxyprogesterone acetate increases anthracycline-induced lipid peroxidation and membrane fluidity.

Journal: Veterinary research communications 20030901

Title: Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia.

Journal: The New England journal of medicine 20030821

Title: Treatment concepts for elderly patients with acute myeloid leukemia.

Journal: Wiener klinische Wochenschrift 20030814

Title: Phase II trial of infusional cyclophosphamide, idarubicin, and etoposide in poor prognosis non-Hodgkin's lymphoma.

Journal: American journal of clinical oncology 20030801

Title: Myeloid/natural killer cell precursor acute leukemia accompanied by homozygous protein C deficiency.

Journal: International journal of hematology 20030801

Title: New designs for phase 2 clinical trials.

Journal: Blood 20030715

Title: Prognosis of inv(16)/t(16;16) acute myeloid leukemia (AML): a survey of 110 cases from the French AML Intergroup.

Journal: Blood 20030715

Title: Dexrazoxane in combination with anthracyclines lead to a synergistic cytotoxic response in acute myelogenous leukemia cell lines.

Journal: Leukemia research 20030701

Title: Pharmacokinetics of idarubicin in the isolated perfused rat lung: effect of cinchonine and rutin.

Journal: Anti-cancer drugs 20030701

Title: MPA increases idarubicin-induced apoptosis in chronic lymphatic leukaemia cells via caspase-3.

Journal: Journal of cellular biochemistry 20030701

Title: Treatment of elderly patients (> or =60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols.

Journal: Leukemia 20030601

Title: Doxorubicin-resistant, MRP1-expressing U-1285 cells are sensitive to idarubicin.

Journal: Therapeutic drug monitoring 20030601

Title: Novel combination chemotherapy for primary (AL) amyloidosis myeloma: clinical, laboratory and serum amyloid-P protein scan improvement.

Journal: British journal of haematology 20030601

Title: Sweet's syndrome masquerading as facial cellulitis.

Journal: Cutis 20030601

Title: Successful treatment for multiple cerebral hemorrhage in a newly diagnosed patient with acute promyelocytic leukemia.

Journal: Leukemia & lymphoma 20030601

Title: [High dose ara-C therapy induced bradycardia in an acute myeloid leukemia patient with inv (16)(p13q22)].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20030601

Title: Non-hodgkins lymphoma.

Journal: Clinical evidence 20030601

Title: Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia.

Journal: Blood 20030501

Title: Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.

Journal: Leukemia research 20030501

Title: Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells.

Journal: International journal of oncology 20030501

Title: Mucormycosis in acute myeloid leukaemia.

Journal: British journal of haematology 20030501

Title: Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030501

Title: The presence of an HLA-identical sibling donor has no impact on outcome of patients with high-risk MDS or secondary AML (sAML) treated with intensive chemotherapy followed by transplantation: results of a prospective study of the EORTC, EBMT, SAKK and GIMEMA Leukemia Groups (EORTC study 06921).

Journal: Leukemia 20030501

Title: Infectious complications in patients with acute promyelocytic leukaemia treated with the AIDA regimen.

Journal: Leukemia 20030501

Title: Timed sequential therapy of acute myelogenous leukemia in adults: a phase II study of retinoids in combination with the sequential administration of cytosine arabinoside, idarubicin and etoposide.

Journal: Leukemia research 20030401

Title: Modeling the metabolism of idarubicin to idarubicinol in rat heart: effect of rutin and phenobarbital.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030401

Title: Acute myelogenous leukemia in an adult with thrombocytopenia with absent radii syndrome.

Journal: European journal of haematology 20030401

Title: HLA-DR antigen-negative acute myeloid leukemia.

Journal: Leukemia 20030401

Title: FLAG-IDA in the treatment of refractory/relapsed acute myeloid leukemia: single-center experience.

Journal: Annals of hematology 20030401

Title: Acute promyelocytic leukemia: a case-based review.

Journal: Hematology (Amsterdam, Netherlands) 20030401

Title: New chiral pool approach to anthracyclinones. The stereoselective synthesis of idarubicinone.

Journal: The Journal of organic chemistry 20030321

Title: Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315

Title: Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority.

Journal: Blood 20030301

Title: Fusion oncogenic tyrosine kinases alter DNA damage and repair after genotoxic treatment: role in drug resistance?

Journal: Leukemia research 20030301

Title: Fatal Bacillus cereus sepsis following resolving neutropenic enterocolitis during the treatment of acute leukemia.

Journal: American journal of hematology 20030301

Title: Interleukin-2 after autologous stem-cell transplantation for adult patients with acute myeloid leukemia in first complete remission.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030215

Title: Effect of imatinib on haematopoietic recovery following idarubicin exposure.

Journal: Leukemia 20030201

Title: Caffeine enhances myocardial uptake of idarubicin but reverses its negative inotropic effect.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030201

Title: Oral induction and consolidation chemotherapy with idarubicin and etoposide in elderly patients with acute myeloid leukemia.

Journal: Haematologica 20030201

Title: High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study.

Journal: Bone marrow transplantation 20030201

Title: Idarubicin containing regimen in multiple myeloma: preliminary results of a pilot study using a modified 'TANDEM' transplant program.

Journal: Leukemia & lymphoma 20030201

Title: Pilot study of Mylotarg, idarubicin and cytarabine combination regimen in patients with primary resistant or relapsed acute myeloid leukemia.

Journal: Cancer chemotherapy and pharmacology 20030101

Title: Early detection of meningeal localization in acute promyelocytic leukaemia patients with high presenting leucocyte count.

Journal: British journal of haematology 20030101

Title: A novel fusion variant of the MORF and CBP genes detected in therapy-related myelodysplastic syndrome with t(10;16)(q22;p13).

Journal: British journal of haematology 20030101

Title: Kinetic analysis of saturable myocardial uptake of idarubicin in rat heart: effect of doxorubicin and hypothermia.

Journal: Pharmaceutical research 20030101

Title: Morphological and biochemical changes in human fibroblast lines induced by anthracyclines during apoptosis.

Journal: Cellular & molecular biology letters 20030101

Title: A case of leukemia of the appendix presenting as acute appendicitis.

Journal: Acta haematologica 20030101

Title: Liposomal formulation of idarubicin.

Journal: Acta poloniae pharmaceutica 20030101

Title: [Efficacy of idarubicin in the treatment of childhood acute non-lymphoblastic leukemia: report of Polish Pediatric Leukemia/Lymphoma Study Group].

Journal: Przeglad lekarski 20030101

Title: Modulation of resistance to idarubicin by the cyclosporin PSC 833 (valspodar) in multidrug-resistant cells.

Journal: Journal of experimental therapeutics & oncology 20030101

Title: Low levels of ABCG2 expression in adult AML blast samples.

Journal: Blood 20021215

Title: Amifostine differentially modulates DNA damage evoked by idarubicin in normal and leukemic cells.

Journal: Leukemia research 20021201

Title: Acute myelogenous leukaemia presenting as a conjunctival lesion and red eye.

Journal: Acta ophthalmologica Scandinavica 20021201

Title: Fludarabine, ARA-C, idarubicin and G-CSF (FLAG-Ida), high dose ARA-C and early stem cell transplant. A feasable and effective therapeutic strategy for de novo AML patients.

Journal: Journal of experimental & clinical cancer research : CR 20021201

Title: Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up.

Journal: Blood 20021101

Title: Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol.

Journal: Leukemia 20021101

Title: Impact of the expression of P glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and heat shock protein 27 on response to induction therapy and long-term survival in patients with de novo acute myeloid leukemia.

Journal: Experimental hematology 20021101

Title: Protective role of antioxidant vitamin E and catechin on idarubicin-induced cardiotoxicity in rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20021101

Title: DNA damage and repair in BCR/ABL-expressing cells after combined action of idarubicin, STI571 and amifostine.

Journal: Anti-cancer drugs 20021101

Title: Treatment of secondary myelodysplastic syndrome after heart transplantation with chemotherapy and nonmyeloablative stem-cell transplantation.

Journal: Transplantation 20021027

Title: Results of consecutive trials for children newly diagnosed with acute myeloid leukemia from the Australian and New Zealand Children's Cancer Study Group.

Journal: Blood 20021015

Title: Successful treatment of acute promyelocytic leukaemia during pregnancy.

Journal: Clinical and laboratory haematology 20021001

Title: Peripheral blood stem cell collection in children with acute leukemia: effectiveness of the 'DIAVE' mobilizing regimen.

Journal: Bone marrow transplantation 20021001

Title: Enterocolitis as initial presentation of acute myelogenous leukemia exacerbated by induction chemotherapy with idarubicin-cytosine arabinoside.

Journal: Mayo Clinic proceedings 20021001

Title: Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience.

Journal: Blood 20020915

Title: A single high dose of idarubicin combined with high-dose ARA-C for treatment of first relapse in childhood 'high-risk' acute lymphoblastic leukaemia: a study of the AIEOP group.

Journal: British journal of haematology 20020901

Title: Acute myocardial infarction as the presenting symptom of acute myeloblastic leukemia with extreme hyperleukocytosis.

Journal: American journal of hematology 20020901

Title: Central nervous system relapse in acute promyelocytic leukemia.

Journal: American journal of hematology 20020901

Title: Evaluation of apoptosis induced in vitro by cladribine (2-CdA) combined with anthracyclines in lymphocytes from patients with B-cell chronic lymphocytic leukemia.

Journal: Annals of hematology 20020901

Title: Primary granulocytic sarcoma of the urinary bladder: case report and review of the literature.

Journal: Urology 20020801

Title: A phase I study of idarubicin dose escalation with amisfostine and high-dose cytarabine in patients with relapsed acute myelogenous leukemia and myelodysplastic syndromes.

Journal: Haematologica 20020801

Title: Neutropenic colitis after treatment of acute myelogenous leukemia with idarubicin and cytosine arabinoside.

Journal: Mayo Clinic proceedings 20020801

Title: FLAG-IDA regimen (fludarabine, cytarabine, idarubicin and G-CSF) in the treatment of patients with high-risk myeloid malignancies.

Journal: Leukemia research 20020801

Title: A single, high dose of idarubicin combined with cytarabine as induction therapy for adult patients with recurrent or refractory acute lymphoblastic leukemia.

Journal: Cancer 20020801

Title: Thrombin as a survival factor for cancer cells: thrombin activation in malignant effusions in vivo and inhibition of idarubicin-induced cell death in vitro.

Journal: International journal of clinical pharmacology and therapeutics 20020801

Title: Enhanced uptake of antisense oligonucleotides using cationic liposomes and the apoptotic effect of idarubicin in K-562 cell line.

Journal: Leukemia research 20020701

Title: [Experience with fludarabine treatment and review of the literature].

Journal: Orvosi hetilap 20020616

Title: Gemtuzumab ozogamicin with or without interleukin 11 in patients 65 years of age or older with untreated acute myeloid leukemia and high-risk myelodysplastic syndrome: comparison with idarubicin plus continuous-infusion, high-dose cytosine arabinoside.

Journal: Blood 20020615

Title: [Diagnostic image (92). A man with fever during chemotherapy. Invasive pulmonary mycosis].

Journal: Nederlands tijdschrift voor geneeskunde 20020615

Title: Experience with gemtuzumab ozogamycin ('mylotarg') and all-trans retinoic acid in untreated acute promyelocytic leukemia.

Journal: Blood 20020601

Title: In vitro evaluation of the efficacy of idarubicin in human tumour cells from patients with low-grade non-Hodgkin's lymphoma.

Journal: British journal of haematology 20020601

Title: Dose escalation therapy in previously untreated patients with multiple myeloma following Z-Dex induction treatment.

Journal: British journal of haematology 20020601

Title: Oral manifestations of acute myelomonocytic leukemia: a case report and review of the classification of leukemias.

Journal: Journal of periodontology 20020601

Title: Troxacitabine-based therapy of refractory leukemia.

Journal: Expert review of anticancer therapy 20020601

Title: Anthracyclines potentiate activity against murine leukemias L1210 and P388 in vivo and in vitro.

Journal: European journal of haematology 20020601

Title: Formation and longevity of idarubicin-induced DNA topoisomerase II cleavable complexes in K562 human leukaemia cells.

Journal: Biochemical pharmacology 20020515

Title: Pharmacokinetics and tissue distribution of idarubicin-loaded solid lipid nanoparticles after duodenal administration to rats.

Journal: Journal of pharmaceutical sciences 20020501

Title: Pharmacodynamic modeling of thrombopoietin, platelet, and megakaryocyte dynamics in patients with acute myeloid leukemia undergoing dose intensive chemotherapy.

Journal: Journal of clinical pharmacology 20020501

Title: Translocation (11;11)(p13- p15;q23) in a child with therapy-related acute myeloid leukemia following chemotherapy with DNA-topoisomerase II inhibitors for Langerhans cell histiocytosis.

Journal: Cancer genetics and cytogenetics 20020501

Title: Comparison of idarubicin and daunorubicin regarding intracellular uptake, induction of apoptosis, and resistance.

Journal: Cancer letters 20020425

Title: Genotoxicity of idarubicin and its modulation by vitamins C and E and amifostine.

Journal: Chemico-biological interactions 20020420

Title: Improved retention of idarubicin after intravenous injection obtained for cholesterol-free liposomes.

Journal: Biochimica et biophysica acta 20020412

Title: Automated differential counts in acute promyelocytic leukemia patients may be misleading.

Journal: Medical and pediatric oncology 20020401

Title: Less intense conditioning with fludarabine, cyclophosphamide, idarubicin and etoposide (FCIE) followed by allogeneic unselected peripheral blood stem cell transplantation in elderly patients with leukemia.

Journal: Leukemia 20020401

Title: Acute basophilic leukemia lacking basophil-specific antigens: the importance of cytokine receptor expression in differential diagnosis.

Journal: International journal of hematology 20020401

Title: Multiple interference of anthracyclines with mitochondrial creatine kinases: preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity.

Journal: Molecular pharmacology 20020301

Title: Phase I trial with escalating doses of idarubicin and multidrug resistance reversal by short-course cyclosporin A, sequential high-dose cytosine arabinoside, and granulocyte colony-stimulating factor for adult patients with refractory acute leukemia.

Journal: Haematologica 20020301

Title: Correlation between chromosome damage and apoptosis induced by fludarabine and idarubicin in normal human lymphocytes.

Journal: Toxicology 20020227

Title: Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.

Journal: Leukemia research 20020201

Title: P-glycoprotein inhibitors enhance saturable uptake of idarubicin in rat heart: pharmacokinetic/pharmacodynamic modeling.

Journal: The Journal of pharmacology and experimental therapeutics 20020201

Title: Retinoic acid syndrome: a case of massive lung consolidation.

Journal: Haematologica 20020201

Title: AIDA treatment for high-risk acute promyelocytic leukemia in a pregnant woman at 21 weeks of gestation.

Journal: Haematologica 20020201

Title: Diversity of the apoptotic response to chemotherapy in childhood leukemia.

Journal: Leukemia 20020201

Title: Cell-based assays for identification of novel double-strand break-inducing agents.

Journal: Journal of the National Cancer Institute 20020116

Title: Standard versus alternative myeloablative conditioning regimens in allogeneic hematopoietic stem cell transplantation for high-risk acute leukemia.

Journal: Haematologica 20020101

Title: Differential antigenotoxic and cytoprotective effect of amifostine in idarubicin-treated mice.

Journal: Environmental and molecular mutagenesis 20020101

Title: Secondary acute promyelocytic leukemia in a patient with non-Hodgkin's lymphoma treated with VP-16 and MST-16.

Journal: International journal of hematology 20020101

Title: [Acute myelogenous leukemia associated with severe esophageal stricture after chemotherapy].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20020101

Title: A case of zygomycosis and invasive candidiasis involving the epiglottis and tongue in an immunocompromised patient.

Journal: Scandinavian journal of infectious diseases 20020101

Title: Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer.

Journal: Drugs & aging 20020101

Title: All trans retinoic acid in combination with intermediate-dose cytarabine and idarubicin in patients with relapsed or refractory non promyelocytic acute myeloid leukemia: a phase II randomized trial.

Journal: The hematology journal : the official journal of the European Haematology Association 20020101

Title: Treatment of non-Hodgkin's lymphoma in the elderly. The Italian studies.

Journal: Tumori 20020101

Title: Idarubicin.

Journal: Tumori 20020101

Title: Does the bcr/abl-mediated increase in the efficacy of DNA repair play a role in the drug resistance of cancer cells?

Journal: Cell biology international 20020101

Title: In vivo use of all-trans retinoic acid prior to induction chemotherapy improves complete remission rate and increases rhodamine 123 uptake in patients with de novo acute myeloid leukemia.

Journal: Medical oncology (Northwood, London, England) 20020101

Title: Pharmacokinetic-pharmacodynamic relationships of the anthracycline anticancer drugs.

Journal: Clinical pharmacokinetics 20020101

Title: A comparison of the in vitro genotoxicity of anticancer drugs idarubicin and mitoxantrone.

Journal: Acta biochimica Polonica 20020101

Title: The influence of intracellular idarubicin and daunorubicin levels on drug cytotoxicity in childhood acute leukemia.

Journal: Acta biochimica Polonica 20020101

Title: Transient dilated cardiomyopathy in a newborn exposed to idarubicin and all-trans-retinoic acid (ATRA) early in the second trimester of pregnancy.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20020101

Title: Inv(4)(p14q27) in a case with de novo acute nonlymphocytic leukemia.

Journal: Acta haematologica 20020101

Title: CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.

Journal: Acta haematologica 20020101

Title: The antineoplastic treatment in the elderly.

Journal: La Clinica terapeutica 20020101

Title: [Minimal residual disease in acute myeloid leukemia in children--standardization and evaluation of immunophenotyping in the AML-BFM-98 study].

Journal: Klinische Padiatrie 20020101

Title: The combination regimen of idarubicin and taxotere is effective against human drug-resistant leukemic cell lines.

Journal: Anticancer research 20020101

Title: Prolonged administration of all-trans retinoic acid in combination with intensive chemotherapy and G-CSF for adult acute myelogenous leukemia: single-centre pilot study in different risk groups.

Journal: The hematology journal : the official journal of the European Haematology Association 20020101

Title: Osteonecrosis of the maxilla as a complication to chemotherapy: a case report.

Journal: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 20020101

Title: Severe hyperglycemia as a complication of big ICE chemotherapy in a patient with acute myeloblastic leukemia.

Journal: Haematologia 20020101

Title: Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts.

Journal: Blood 20011215

Title: Treatment of relapse after allogeneic bone marrow transplantation with reduced intensity conditioning (FLAG +/- Ida) and second allogeneic stem cell transplant.

Journal: British journal of haematology 20011201

Title: Idarubicin, cytarabine, and topotecan in patients with refractory or relapsed acute myelogenous leukemia and high-risk myelodysplastic syndrome.

Journal: American journal of hematology 20011201

Title: Generation of reactive oxygen species is not involved in idarubicin-induced apoptosis in human leukaemic cells.

Journal: British journal of haematology 20011201

Title: An adjustment for a post-randomization variable in the comparison of two treatments for survival.

Journal: Statistics in medicine 20011130

Title: Anthracyclines: recent developments in their separation and quantitation.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20011125

Title: Inappropriate reporting and interpretation of subgroups in the AML-BFM 93 study.

Journal: Leukemia 20011101

Title: And the sun keeps shining.

Journal: The Journal of pediatrics 20011101

Title: Influence of P-glycoprotein modulators on cardiac uptake, metabolism, and effects of idarubicin.

Journal: Pharmaceutical research 20011101

Title: Development of hepatic veno-occlusive disease after Mylotarg infusion for relapsed acute myeloid leukemia.

Journal: Bone marrow transplantation 20011101

Title: Intensive chemotherapy followed by allogeneic or autologous stem cell transplantation for patients with myelodysplastic syndromes (MDSs) and acute myeloid leukemia following MDS.

Journal: Blood 20011015

Title: High-dose chemotherapy in high-risk myelodysplastic syndrome: covariate-adjusted comparison of five regimens.

Journal: Cancer 20011015

Title: Spectroscopic studies on iron complexes of different anthracyclines in aprotic solvent systems.

Journal: Inorganic chemistry 20011008

Title: High dose of idarubicin-based regimen for diffuse large cell AIDS-related non-Hodgkin's lymphoma patients: a pilot study.

Journal: Haematologica 20011001

Title: LFA-1 and ICAM-1 antibody-idarubicin conjugates separately prolong murine cardiac allograft survival.

Journal: Transplant immunology 20011001

Title: A pharmacokinetic study of idarubicin in Japanese patients with malignant lymphoma: relationship with leukocytopenia and neutropenia.

Journal: International journal of hematology 20011001

Title: FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.

Journal: European journal of haematology 20011001

Title: Tolerance in baboon kidney transplantation with total lymphoid irradiation (TLI) and anti-CD3/CD4-idarubicin conjugates.

Journal: Transplantation 20010927

Title: Effects of glycosylated recombinant human granulocyte colony-stimulating factor after high-dose cytarabine-based induction chemotherapy for adult acute myeloid leukaemia.

Journal: Leukemia 20010901

Title: Synergism between fludarabine and rituximab revealed in a follicular lymphoma cell line resistant to the cytotoxic activity of either drug alone.

Journal: British journal of haematology 20010901

Title: Granulomatous tubulointerstitial nephritis induced by all-trans retinoic acid.

Journal: Anti-cancer drugs 20010901

Title: Drug-drug interactions arising from the use of liposomal vincristine in combination with other anticancer drugs.

Journal: Pharmaceutical research 20010901

Title: [Comparison of the effectiveness of idarubicin (Zavedos) and mitoxantrone (Refador) in induction therapy of acute myeloid leukemia in elderly patients (55-75) (a prospective multicenter randomized study conducted 1998-2000].

Journal: Vnitrni lekarstvi 20010901

Title: [CD7(+) acute myeloid leukemia (M0) associated with a mediastinal bulky mass lesion].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20010801

Title: Acute basophilic leukemia.

Journal: European journal of haematology 20010801

Title: Treatment of acute promyelocytic leukaemia using a combination of all-trans retinoic acid and chemotherapy.

Journal: Annals of the Academy of Medicine, Singapore 20010701

Title: Treatment of newly-diagnosed acute promyelocytic leukemia with liposomal all-trans retinoic acid.

Journal: Leukemia & lymphoma 20010701

Title: Cytosine arabinoside, idarubicin and divided dose etoposide for the treatment of acute myeloid leukemia in elderly patients.

Journal: Leukemia & lymphoma 20010701

Title: Oligonucleotide enhanced cytotoxicity of Idarubicin for lymphoma cells.

Journal: Leukemia & lymphoma 20010701

Title: The combined effect of IDA and glutaraldehyde on the properties of human erythrocytes.

Journal: International journal of pharmaceutics 20010604

Title: High-dose cytosine arabinoside and idarubicin treatment of chronic myeloid leukemia in myeloid blast crisis.

Journal: American journal of hematology 20010601

Title: The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.

Journal: Leukemia 20010601

Title: Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.

Journal: Leukemia 20010601

Title: The cellular and molecular basis of health benefits of grape seed proanthocyanidin extract.

Journal: Current pharmaceutical biotechnology 20010601

Title: Chemotherapy for mobilisation of Ph-negative progenitor cells from patients with CML: impact of different mobilisation regimens.

Journal: Bone marrow transplantation 20010601

Title: Improved treatment results in high-risk pediatric acute myeloid leukemia patients after intensification with high-dose cytarabine and mitoxantrone: results of Study Acute Myeloid Leukemia-Berlin-Frankfurt-Münster 93.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515

Title: Combination chemotherapy of intermediate-dose cytarabine, idarubicin, plus etoposide and subsequent mobilized donor leukocyte infusion for relapsed acute leukemia after allogeneic bone marrow transplantation.

Journal: Leukemia research 20010401

Title: Arsenic trioxide- and idarubicin-induced remissions in relapsed acute promyelocytic leukaemia: clinicopathological and molecular features of a pilot study.

Journal: American journal of hematology 20010401

Title: Acute promyelocytic leukemia with additional chromosome abnormalities in a renal transplant case.

Journal: Annals of hematology 20010401

Title: Double reinforcement with fludarabine/high-dose cytarabine enhances the impact of autologous stem cell transplantation in acute myeloid leukemia patients.

Journal: Bone marrow transplantation 20010401

Title: Successful salvage of RAEB/AML relapsing early post allograft with FLAG-Ida conditioned mini-allograft: a report of two cases.

Journal: Clinical and laboratory haematology 20010401

Title: Isodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: a new clinical entity?

Journal: Genes, chromosomes & cancer 20010301

Title: Severe hepatic injury associated with lipid formulations of amphotericin B.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010301

Title: Idarubicin improves blast cell clearance during induction therapy in children with AML: results of study AML-BFM 93. AML-BFM Study Group.

Journal: Leukemia 20010301

Title: Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.

Journal: European journal of haematology 20010301

Title: Topoisomerase II inhibitor induced leukemia in a patient with AIDS.

Journal: AIDS (London, England) 20010216

Title: Transfusion of peripheral blood stem cells from donor homozygous for a shared HLA-haplotype: avoiding fatal transfusion-associated graft-versus-host disease while preserving anti-leukemic effect.

Journal: Transplantation 20010215

Title: Bilateral breast relapse in acute myelogenous leukemia.

Journal: Journal of pediatric hematology/oncology 20010201

Title: PBPC mobilization with chemotherapy and G-CSF in patients with chronic myeloid leukemia: quantification of bcr/abl-positive cells by interphase fluorescence in situ hybridization and competitive PCR.

Journal: Transfusion 20010101

Title: Simultaneous determination of doxorubicin, daunorubicin, and idarubicin by capillary electrophoresis with laser-induced fluorescence detection.

Journal: Electrophoresis 20010101

Title: Results of IDA-FLAG programme in the treatment of recurrent acute myeloblastic leukaemia--preliminary report.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20010101

Title: [Outcome of acute myelogenous leukemia in 41 patients treated with idarubicin: the prognosis of t(8;21) cases].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20010101

Title: Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance.

Journal: Leukemia 20010101

Title: Risk-oriented postremission strategies in adult acute lymphoblastic leukemia: prospective confirmation of anthracycline activity in standard-risk class and role of hematopoietic stem cell transplants in high-risk groups.

Journal: The hematology journal : the official journal of the European Haematology Association 20010101

Title: Fludarabine, arabinosyl cytosine and idarubicin (FLAI) for remission induction in poor-risk acute myeloid leukemia.

Journal: Leukemia & lymphoma 20010101

Title: Tumour kinetics in multiple myeloma before, during, and after treatment.

Journal: Leukemia & lymphoma 20010101

Title: Intensive postremission chemotherapy in Taiwanese adults with acute myelogenous leukemia.

Journal: Advances in therapy 20010101

Title: [Improved treatment results in children with AML: Results of study AML-BFM 93].

Journal: Klinische Padiatrie 20010101

Title: Autologous hematopoietic stem cell transplantation in chronic myeloid leukemia with different clinical stages.

Journal: Acta haematologica 20010101

Title: Pharmacokinetics and toxicity of idarubicin in the rat.

Journal: European journal of drug metabolism and pharmacokinetics 20010101

Title: High-dose idarubicin and busulphan as conditioning for autologous stem cell transplantation in acute myeloid leukemia: a feasibility study.

Journal: The hematology journal : the official journal of the European Haematology Association 20010101

Title: Misdiagnosis of broad-complex tachycardia.

Journal: Heart & lung : the journal of critical care 20000101

Title: Idarubicin, melphalan and cyclophosphamide: an intensified high-dose regimen for the treatment of myeloma patients.

Journal: Leukemia 19971201

Title: Peripheral blood progenitor cell mobilisation in patients with multiple myeloma following oral idarubicin and dexamethasone (Z-Dex) induction therapy.

Journal: Leukemia 19971201

Title: Myelodysplastic syndrome following successful therapy of acute promyelocytic leukemia.

Journal: Leukemia 19970101

Title: All-trans-retinoic acid (ATRA) responsive skin relapses of acute promyelocytic leukaemia followed by ATRA-induced pseudotumour cerebri.

Journal: British journal of haematology 19960301

Title: Intravesical idarubicin: a dose-finding study.

Journal: Cancer chemotherapy and pharmacology 19960101

Title: [Acute myocardial infarction after cytostatic therapy].

Journal: Lakartidningen 19951122

Title: Idarubicin cardiotoxicity: a retrospective study in acute myeloid leukemia and myelodysplasia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19951101

Title: Angiotensin converting enzyme inhibitors in bone marrow transplant recipients with depressed left ventricular function.

Journal: Bone marrow transplantation 19950601

Title: Radiation recall reaction to idarubicin resulting in vaginal necrosis.

Journal: Gynecologic oncology 19950501

Title: Idarubicin, high-dose cytarabine and etoposide for remission induction in therapy-related acute myeloid leukemia.

Journal: Leukemia & lymphoma 19940901

Title: Sick sinus syndrome in a teenager treated with idarubicin.

Journal: Journal of cardiothoracic and vascular anesthesia 19930201

Title: Idarubicin cardiotoxicity in acute myeloid leukaemia.

Journal: Lancet (London, England) 19920718

Title: Phase II study of intravenous idarubicin in unfavorable non-Hodgkin's lymphoma.

Journal: Cancer research 19920715

Title: New anthracycline antitumor antibiotics.

Journal: Critical reviews in oncology/hematology 19910101

Title: Evaluation of cardiac toxicity of idarubicin (4-demethoxydaunorubicin).

Journal: European journal of cancer & clinical oncology 19890101

Title: 4-Demethoxydaunorubicin administered orally in advanced breast cancer. A phase II study.

Journal: Tumori 19880227

Title: Phase II trial of idarubicin in patients with advanced lymphoma.

Journal: Cancer chemotherapy and pharmacology 19880101

Title: Selective mitochondrial alterations induced by a single dose of daunorubicin or 4-demethoxydaunorubicin in mouse ventricular myocardium.

Journal: Tumori 19800201

Title: Orlandi P, et al. Idarubicin and idarubicinol effects on breast cancer multicellular spheroids. J Chemother. 2005 Dec;17(6):663-7.

Title: Robert J. Clinical pharmacokinetics of idarubicin. Clin Pharmacokinet. 1993 Apr;24(4):275-88.

Title: Siegsmund MJ, et al. Enhanced in vitro cytotoxicity of idarubicin compared to epirubicin and doxorubicin in rat prostate carcinoma cells. Eur Urol. 1997;31(3):365-70.

Title: Gewirtz DA, et al. Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line. Cancer Chemother Pharmacol. 1998;41(5):361-

Title: Kinnunen U, et al. Idarubicin inhibits the growth of bacteria and yeasts in an automated blood culture system. Eur J Clin Microbiol Infect Dis. 2009 Mar;28(3):301-3.

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Tags:57852-57-0 Molecular Formula|57852-57-0 MDL|57852-57-0 SMILES|57852-57-0 Idarubicin Hydrochloride