Name: Name:N'-hydroxybenzenecarboximidamide hydrochloride
Brand: AABLOCKS
SKU: AA01B9JO
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01B9JO

Chemical Name: N'-hydroxybenzenecarboximidamide hydrochloride

CAS Number: 99277-23-3

Molecular Formula: C7H9ClN2O

Molecular Weight: 172.6122

MDL Number: MFCD06656049

SMILES: ON=C(c1ccccc1)N.Cl

Properties

Complexity: 128

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Downstream Synthesis Route

99277-23-3

74-86-2

N'-(vinyloxy)benzenecarboximidamide

[1]Trofimov;Schmidt;Vasil'Tsov;Mikhaleva;Zaitsev;Morozova;Gorshkov;Henkelmann;Arndt[Synthesis,2001,#16,p.2427-2430]

99277-23-3

1736-55-6

[1]Trofimov;Schmidt;Vasil'Tsov;Mikhaleva;Zaitsev;Morozova;Gorshkov;Henkelmann;Arndt[Synthesis,2001,#16,p.2427-2430]

Literature fold

Title: Insight into technetium amidoxime complex: oxo technetium(V) complex of N-substituted benzamidoxime as new basic structure for molecular imaging.

Journal: Inorganic chemistry20110207

Title: Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).

Journal: The Biochemical journal20110115

Title: A novel and specific fluorescence reaction for uracil.

Journal: Analytica chimica acta20100803

Title: The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs.

Journal: Journal of medicinal chemistry20081225

Title: Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20080901

Title: Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme.

Journal: The Journal of biological chemistry20061117

Title: Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).

Journal: Drug metabolism and disposition: the biological fate of chemicals20051101

Title: Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050401

Title: Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20050101

Title: Phase 2 metabolites of N-hydroxylated amidines (amidoximes): synthesis, in vitro formation by pig hepatocytes, and mutagenicity testing.

Journal: Chemical research in toxicology20010301

99277-23-3 | N'-hydroxybenzenecarboximidamide hydrochloride