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509-80-8,MFCD01861514
Catalog No.:AA01DDDK

509-80-8 | Mitraphylline

Pack Size
Purity
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5mg
98% by HPLC
in stock  
$201.00   $141.00
- +
10mg
98% by HPLC
in stock  
$296.00   $207.00
- +
25mg
98% by HPLC
in stock  
$555.00   $389.00
- +
50mg
98% by HPLC
in stock  
$900.00   $630.00
- +
100mg
98% by HPLC
in stock  
$1,511.00   $1,058.00
- +
500mg
98% by HPLC
in stock  
$4,737.00   $3,316.00
- +
1000mg
98% by HPLC
in stock  
$7,541.00   $5,279.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DDDK
Chemical Name:
Mitraphylline
CAS Number:
509-80-8
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.4263
MDL Number:
MFCD01861514
SMILES:
COC(=O)C1=CO[C@H]([C@@H]2[C@@H]1C[C@@H]1N(C2)CC[C@@]21C(=O)Nc1c2cccc1)C
NSC Number:
717700
Properties
Computed Properties
 
Complexity:
692  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
1.6  

Literature

Title: Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline.

Journal: Planta medica 20140501

Title: HPLC analysis of oxindole alkaloids in Uncaria tomentosa: sample preparation and analysis optimisation by factorial design.

Journal: Phytochemical analysis : PCA 20120101

Title: Analysis of mitragynine and metabolites in human urine for detecting the use of the psychoactive plant kratom.

Journal: Journal of analytical toxicology 20120101

Title: Cytotoxic effect of the pentacyclic oxindole alkaloid mitraphylline isolated from Uncaria tomentosa bark on human Ewing's sarcoma and breast cancer cell lines.

Journal: Planta medica 20100201

Title: Antiproliferative effects of mitraphylline, a pentacyclic oxindole alkaloid of Uncaria tomentosa on human glioma and neuroblastoma cell lines.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20070401

Title: Heteroyohimbinoid type oxindole alkaloids from Mitragyna parvifolia.

Journal: Phytochemistry 20061001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells.

Journal: British journal of haematology 20060301

Title: Montserrat-de la Paz S, et al. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils. Phytomedicine. 2016 Feb 15;23(2):141-8.

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Tags:509-80-8 Molecular Formula|509-80-8 MDL|509-80-8 SMILES|509-80-8 Mitraphylline