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Home Other Building Blocks 957118-49-9
957118-49-9,MFCD16038933
Catalog No.:AA01DOKL

957118-49-9 | MK-3207

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$168.00   $117.00
- +
5mg
99%
1 week  
$355.00   $249.00
- +
10mg
99%
1 week  
$574.00   $402.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DOKL
Chemical Name:
MK-3207
CAS Number:
957118-49-9
Molecular Formula:
C31H29F2N5O3
Molecular Weight:
557.5905
MDL Number:
MFCD16038933
SMILES:
O=C(CN1C(CNC2(C1=O)CCCC2)c1cc(F)cc(c1)F)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2c1cccn2
Properties
Computed Properties
 
Complexity:
1040  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
2.8  

Literature

Title: Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine.

Journal: Cephalalgia : an international journal of headache 20110401

Title: Possible site of action of CGRP antagonists in migraine.

Journal: Cephalalgia : an international journal of headache 20110401

Title: Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 20100401

Title: Salvatore CA, Moore EL, Calamari A, Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonist. J Pharmacol Exp Ther. 2010 Apr;333(1):152-60.

Title: Hewitt DJ, Aurora SK, Dodick DW, Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine. Cephalalgia. 2011 Apr;31(6):712-22.

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SDS
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