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67814-76-0,MFCD01683537
Catalog No.:AA01DQ1E

67814-76-0 | Isepamicin Sulphate

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1mg
98%
in stock  
$14.00   $10.00
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5mg
98%
in stock  
$34.00   $24.00
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25mg
98%
in stock  
$78.00   $55.00
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100mg
95%
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$247.00   $173.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DQ1E
Chemical Name:
Isepamicin Sulphate
CAS Number:
67814-76-0
Molecular Formula:
C22H45N5O16S
Molecular Weight:
667.6816
MDL Number:
MFCD01683537
SMILES:
OS(=O)(=O)O.NC[C@@H](C(=O)N[C@@H]1C[C@H](N)[C@H]([C@@H]([C@H]1O[C@H]1OC[C@]([C@@H]([C@H]1O)NC)(C)O)O)O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1O)O)O)O
Properties
Computed Properties
 
Complexity:
899  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
15  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
20  
Hydrogen Bond Donor Count:
14  
Rotatable Bond Count:
9  

Literature

Title: Antimicrobial susceptibility of non-fermenting Gram-negative isolates to isepamicin in a region with high antibiotic resistance.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20121101

Title: Susceptibility of Gram-negative bacteria to isepamicin: a systematic review.

Journal: Expert review of anti-infective therapy 20120201

Title: Necrotic intramuscular chloroma with infection: magnetic resonance imaging features.

Journal: Japanese journal of radiology 20111201

Title: Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis.

Journal: Biochemical and biophysical research communications 20100903

Title: Resonance Rayleigh-scattering spectral method for the determination of some aminoglycoside antibiotics using CdTe quantum dots as a probe.

Journal: Luminescence : the journal of biological and chemical luminescence 20100101

Title: Prophylactic use of isepamicin and levofloxacin for transrectal prostate biopsy: a retrospective single center study.

Journal: International journal of urology : official journal of the Japanese Urological Association 20090901

Title: Determination of isepamicin in human plasma by HPLC with fluorescence detection after derivatization using 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate.

Journal: Biological & pharmaceutical bulletin 20081001

Title: Research and clinical value of antibacterial-application software.

Journal: Chinese medical journal 20080105

Title: In vitro activity of isepamicin and other aminoglycosides against clinical isolates of Gram-negative bacteria causing nosocomial bloodstream infections.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20071201

Title: Old antibiotics for infections in critically ill patients.

Journal: Current opinion in critical care 20071001

Title: Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease.

Journal: Journal of chemotherapy (Florence, Italy) 20051001

Title: A case of pneumonia caused by Ewingella americana in a patient with chronic renal failure.

Journal: Journal of Korean medical science 20050201

Title: In vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in Taiwan.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20050101

Title: [Isepamycin in prophylaxis and treatment of experimental plague due to FI+ and FI- variants of plague microbe].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

Title: High release of antibiotic from a novel hydroxyapatite with bimodal pore size distribution.

Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20040815

Title: Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501

Title: [Aminoglycoside resistance in gramnegative pathogens of nosocomial infections in Russia].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101

Title: [Iliopsoas abscess accompanied by epidural abscess--a case report].

Journal: Masui. The Japanese journal of anesthesiology 20030901

Title: A case of Pasteurella haemolytica sepsis in a patient with mitral valve disease who developed a splenic abscess.

Journal: Scandinavian journal of infectious diseases 20030101

Title: [Antibacterial activities and PK/PD parameters of aminoglycosides against recent clinical isolates of gram-negative rods].

Journal: The Japanese journal of antibiotics 20021001

Title: Diffusion of isepamicin into cancellous and cortical bone tissue.

Journal: Journal of chemotherapy (Florence, Italy) 20020801

Title: Protective effect of fleroxacin against the nephrotoxicity of isepamicin in rats.

Journal: Biological & pharmaceutical bulletin 20020401

Title: [In vitro interaction of tazobactam/piperacillin combined with aminoglycosides against Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli AND Staphylococcus aureus].

Journal: The Japanese journal of antibiotics 20020201

Title: Invitro comparative evaluation of aminoglycosides at a cancer centre.

Journal: Indian journal of cancer 20020101

Title: Comparison of isepamicin with amikacin for the empirical treatment of febrile neutropenic children with malignancies.

Journal: International journal of antimicrobial agents 20011001

Title: Cloning, overexpression, and purification of aminoglycoside antibiotic nucleotidyltransferase (2'')-Ia: conformational studies with bound substrates.

Journal: Biochemistry 20010619

Title: Comparison of two methods to obtain a desired first isepamicin peak in intensive care patients.

Journal: Fundamental & clinical pharmacology 20010401

Title: In vitro susceptibility of nosocomial isolates against a new aminoglycoside isepamicin.

Journal: The Indian journal of medical research 20010201

Title: Determination of isepamicin sulfate and related compounds by high performance liquid chromatography using evaporative light scattering detection.

Journal: Journal of pharmaceutical and biomedical analysis 20010101

Title: Comparative activities of isepamicin, amikacin, cefepime, and ciprofloxacin alone or in combination with other antibiotics against Stenotrophomonas maltophilia.

Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010101

Title: Neuromuscular blocking effects of the aminoglycoside antibiotics arbekacin, astromicin, isepamicin and netilmicin on the diaphragm and limb muscles in the rabbit.

Journal: Pharmacology 20010101

Title: Comparative in vitro activity of isepamicin and other antibiotics against gram-negative bacilli from intensive care units (ICU) in Belgium.

Journal: Acta clinica Belgica 20010101

Title: Auditory impairment in guinea pigs treated with isepamicin.

Journal: Journal of chemotherapy (Florence, Italy) 19950601

Title: CI-960 (PD127391 or AM-1091), sparfloxacin, WIN 57273, and isepamicin activity against clinical isolates of Mycobacterium avium-intracellularae complex, M. chelonae, and M. fortuitum.

Journal: Diagnostic microbiology and infectious disease 19920201

Title: Samonis G, et al. Antimicrobial susceptibility of non-fermenting Gram-negative isolates to isepamicin in a region with high antibiotic resistance. Eur J Clin Microbiol Infect Dis. 2012 Nov;31(11):3191-8.

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