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Home Other Building Blocks 1336960-13-4
1336960-13-4,MFCD28009510
Catalog No.:AA01E13O

1336960-13-4 | GSK2193874

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$23.00   $16.00
- +
5mg
98%
in stock  
$74.00   $52.00
- +
10mg
98%
in stock  
$111.00   $78.00
- +
500mg
98% by HPLC
in stock  
$3,958.00   $2,771.00
- +
1000mg
98% by HPLC
in stock  
$6,295.00   $4,407.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01E13O
Chemical Name:
GSK2193874
CAS Number:
1336960-13-4
Molecular Formula:
C37H38BrF3N4O
Molecular Weight:
691.6230
MDL Number:
MFCD28009510
SMILES:
Brc1ccc2c(c1)nc(c(c2C(=O)NC1(CC1)c1ccccc1)CN1CCC(CC1)N1CCCCC1)c1cccc(c1)C(F)(F)F
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
7.8  

Literature

Title: Cheung M, et al. Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4. ACS Med Chem Lett. 2017 Mar 20;8(5):549-554.

Title: Thorneloe KS, et al. An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. Sci Transl Med. 2012 Nov 7;4(159):159ra148.

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SDS
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Tags:1336960-13-4 Molecular Formula|1336960-13-4 MDL|1336960-13-4 SMILES|1336960-13-4 GSK2193874