+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 1650550-25-6
1650550-25-6,MFCD30489472
Catalog No.:AA01E6RV

1650550-25-6 | Enasidenib Mesylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$130.00   $91.00
- +
10mg
99%
1 week  
$177.00   $124.00
- +
50mg
99%
1 week  
$273.00   $191.00
- +
100mg
99%
1 week  
$336.00   $235.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01E6RV
Chemical Name:
Enasidenib Mesylate
CAS Number:
1650550-25-6
Molecular Formula:
C20H21F6N7O4S
Molecular Weight:
569.4807
MDL Number:
MFCD30489472
SMILES:
CC(CNc1nc(Nc2ccnc(c2)C(F)(F)F)nc(n1)c1cccc(n1)C(F)(F)F)(O)C.CS(=O)(=O)O
Properties
Computed Properties
 
Complexity:
727  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
17  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  

Downstream Synthesis Route

[1]CurrentPatentAssignee:SERVIERMONDE-WO2015/18060,2015,A1

[2]CurrentPatentAssignee:SERVIERMONDE-WO2015/17821,2015,A2

[3]CurrentPatentAssignee:SERVIERMONDE-US2018/311249,2018,A1

[1]CurrentPatentAssignee:SERVIERMONDE-WO2015/18060,2015,A1

[2]CurrentPatentAssignee:SERVIERMONDE-US2018/311249,2018,A1

75-75-2    1446502-11-9   
2-methyl-1-(4-6-(trifluoromethyl)pyridin-2-yl-6-2-(trifluoromethyl)pyridin-4-ylamino}-1,3,5-triazin-2-yl)aminopropan-2-olmethanesulfonate 

[1]Patent:WO2015/18060,2015,A1.Locationinpatent:Page/Pagecolumn53-54

[2]Patent:WO2015/17821,2015,A2.Locationinpatent:Page/Pagecolumn69

[3]Patent:US2018/311249,2018,A1.Locationinpatent:Paragraph0349

368-48-9   
2-methyl-1-(4-6-(trifluoromethyl)pyridin-2-yl-6-2-(trifluoromethyl)pyridin-4-ylamino}-1,3,5-triazin-2-yl)aminopropan-2-olmethanesulfonate 

[1]Patent:WO2015/18060,2015,A1

[2]Patent:US2018/311249,2018,A1

131747-42-7   
2-methyl-1-(4-6-(trifluoromethyl)pyridin-2-yl-6-2-(trifluoromethyl)pyridin-4-ylamino}-1,3,5-triazin-2-yl)aminopropan-2-olmethanesulfonate 

[1]Patent:WO2015/18060,2015,A1

[2]Patent:WO2015/17821,2015,A2

[3]Patent:US2018/311249,2018,A1

Literature

Title: Exploring the Pathway: IDH Mutations and Metabolic Dysregulation in Cancer Cells: A Novel Therapeutic Target. MAY 29, 2015

Title: Alan H. Shih, et al. AG-221, a Small Molecule Mutant IDH2 Inhibitor, Remodels the Epigenetic State of IDH2-Mutant Cells and Induces Alterations in Self-Renewal/Differentiation in IDH2-Mutant AML Model in Vivo. Blood 2014 124:437.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1650550-25-6
1446502-11-9

1446502-11-9
Building Blocks
More >
Tags:1650550-25-6 Molecular Formula|1650550-25-6 MDL|1650550-25-6 SMILES|1650550-25-6 Enasidenib Mesylate