Title: Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats.
Journal: Anesthesiology 20120801
Title: Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action.
Journal: Circulation 20120605
Title: Delayed treatment with lidocaine reduces mouse microglial cell injury and cytokine production after stimulation with lipopolysaccharide and interferon γ.
Journal: Anesthesia and analgesia 20120401
Title: The generation of direction selectivity in the auditory system.
Journal: Neuron 20120308
Title: Development of synaptic connectivity onto interneurons in stratum radiatum in the CA1 region of the rat hippocampus.
Journal: BMC neuroscience 20120101
Title: α7-Containing and non-α7-containing nicotinic receptors respond differently to spillover of acetylcholine.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019
Title: Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review.
Journal: British journal of pharmacology 20110901
Title: Sound rhythms are encoded by postinhibitory rebound spiking in the superior paraolivary nucleus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110831
Title: Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons.
Journal: Nature neuroscience 20110703
Title: Characterization of dental nociceptive neurons.
Journal: Journal of dental research 20110601
Title: Multiple inhibitory actions of lidocaine on Torpedo nicotinic acetylcholine receptors transplanted to Xenopus oocytes.
Journal: Journal of neurochemistry 20110601
Title: The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro.
Journal: Anesthesiology 20110601
Title: Use-dependent AMPA receptor block reveals segregation of spontaneous and evoked glutamatergic neurotransmission.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110406
Title: Long-term self-renewable feeder-free human induced pluripotent stem cell-derived neural progenitors.
Journal: Stem cells and development 20110301
Title: Induction of TRPV1 desensitization by a biased receptor agonist.
Journal: Channels (Austin, Tex.) 20110101
Title: Activation of TRPA1 by membrane permeable local anesthetics.
Journal: Molecular pain 20110101
Title: Acid solution is a suitable medium for introducing QX-314 into nociceptors through TRPV1 channels to produce sensory-specific analgesic effects.
Journal: PloS one 20110101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: [Potentials for differential block with local anesthetics].
Journal: Masui. The Japanese journal of anesthesiology 20101101
Title: Active roles of electrically coupled bipolar cell network in the adult retina.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100707
Title: Selectively targeting pain in the trigeminal system.
Journal: Pain 20100701
Title: Asymmetric rostro-caudal inhibition in the primary olfactory cortex.
Journal: Nature neuroscience 20100501
Title: N-ethyl lidocaine (QX-314) protects striatal neurons against ischemia: an in vitro electrophysiological study.
Journal: Synapse (New York, N.Y.) 20100201
Title: Local anesthetic effects on human neutrophil priming and activation.
Journal: Regional anesthesia and pain medicine 20100101
Title: Involvement of nicotinic and muscarinic receptors in the endogenous cholinergic modulation of the balance between excitation and inhibition in the young rat visual cortex.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20091001
Title: Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior.
Journal: Molecular psychiatry 20090701
Title: Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patterns.
Journal: Journal of neurophysiology 20090701
Title: Coapplication of lidocaine and the permanently charged sodium channel blocker QX-314 produces a long-lasting nociceptive blockade in rodents.
Journal: Anesthesiology 20090701
Title: QX-314 produces long-lasting local anesthesia modulated by transient receptor potential vanilloid receptors in mice.
Journal: Anesthesiology 20090701
Title: Homeostatic presynaptic suppression of neuronal network bursts.
Journal: Journal of neurophysiology 20090401
Title: Nociceptive behavior induced by mustard oil injection into the temporomandibular joint is blocked by a peripheral non-opioid analgesic and a central opioid analgesic.
Journal: Pharmacology, biochemistry, and behavior 20090101
Title: Pore dilation occurs in TRPA1 but not in TRPM8 channels.
Journal: Molecular pain 20090101
Title: Postsynaptic action potentials are required for nitric-oxide-dependent long-term potentiation in CA1 neurons of adult GluR1 knock-out and wild-type mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081224
Title: Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity.
Journal: The Journal of physiology 20081215
Title: Access and binding of local anesthetics in the closed sodium channel.
Journal: Molecular pharmacology 20081001
Title: Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.
Journal: Neuron 20080710
Title: Lidocaine increases intracellular sodium concentration through a Na+-H+ exchanger in an identified Lymnaea neuron.
Journal: Anesthesia and analgesia 20080501
Title: Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels.
Journal: Circulation research 20080104
Title: Chillies: out of the frying pan and into the clinic?
Journal: Lancet (London, England) 20071013
Title: Neuroscience: a local route to pain relief.
Journal: Nature 20071004
Title: Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Journal: Nature 20071004
Title: Long-term depression requires postsynaptic AMPA GluR2 receptor in adult mouse cingulate cortex.
Journal: Journal of cellular physiology 20070501
Title: Role of persistent sodium current in mouse preBötzinger Complex neurons and respiratory rhythm generation.
Journal: The Journal of physiology 20070415
Title: Involvement of persistent Na+ current in spike initiation in primary sensory neurons of the rat mesencephalic trigeminal nucleus.
Journal: Journal of neurophysiology 20070301
Title: Dendritic calcium spikes induce bi-directional synaptic plasticity in the lateral amygdala.
Journal: Neuropharmacology 20070101
Title: An N-methyl-D-aspartate receptor mediated large, low-frequency, spontaneous excitatory postsynaptic current in neonatal rat spinal dorsal horn neurons.
Journal: Neuroscience 20060901
Title: Pharmacology of a slowly inactivating outward current in hippocampal CA3 pyramidal neurons.
Journal: Journal of neurophysiology 20060901
Title: Olfactory nerve stimulation-evoked mGluR1 slow potentials, oscillations, and calcium signaling in mouse olfactory bulb mitral cells.
Journal: Journal of neurophysiology 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Impaired feedforward inhibition of the thalamocortical projection in epileptic Ca2+ channel mutant mice, tottering.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315
Title: NMDA receptors in layer 4 spiny stellate cells of the mouse barrel cortex contain the NR2C subunit.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060111
Title: Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue.
Journal: Pflugers Archiv : European journal of physiology 20051201
Title: Behaviorally relevant endocannabinoid action in hippocampus: dependence on temporal summation of multiple inputs.
Journal: Behavioural pharmacology 20050901
Title: Synaptic depolarizing GABA Response in adults is excitatory and proconvulsive when GABAB receptors are blocked.
Journal: Journal of neurophysiology 20050501
Title: Sodium channels in transient retinal bipolar cells enhance visual responses in ganglion cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216
Title: Presenilin attenuates receptor-mediated signaling and synaptic function.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050209
Title: Evidence for the involvement of endogenous ATP and P2X receptors in TMJ pain.
Journal: European journal of pain (London, England) 20050201
Title: Membrane bistability in thalamic reticular neurons during spindle oscillations.
Journal: Journal of neurophysiology 20050101
Title: Metabotropic glutamate receptor 2 modulates excitatory synaptic transmission in the rat globus pallidus.
Journal: Neuropharmacology 20050101
Title: The cortically evoked secondary depolarization affects the integrative properties of thalamic reticular neurons.
Journal: The European journal of neuroscience 20041101
Title: [The filter region of the myocardial Na channel, together with ion selectivity, controls pharmacodynamics of anti-arrhythmia agents--an analysis using the channel altered by idiopathic ventricular fibrillation].
Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20041101
Title: Local anesthetics inhibit thromboxane A2 signaling in Xenopus oocytes and human k562 cells.
Journal: Anesthesia and analgesia 20040901
Title: Contribution of intrinsic neuronal factors in the generation of cortically driven electrographic seizures.
Journal: Journal of neurophysiology 20040801
Title: Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access.
Journal: Molecular pharmacology 20040801
Title: Serotonergic facilitation of synaptic activity in the developing rat prefrontal cortex.
Journal: The Journal of physiology 20040501
Title: NMDA receptor-mediated depolarizing after-potentials in the basal dendrites of CA1 pyramidal neurons.
Journal: Neuroscience research 20040301
Title: Local anaesthetics block hyperpolarization-activated inward current in rat small dorsal root ganglion neurones.
Journal: British journal of pharmacology 20030801
Title: Functional significance of cannabinoid-mediated, depolarization-induced suppression of inhibition (DSI) in the hippocampus.
Journal: Journal of neurophysiology 20030701
Title: Independent neuronal oscillators of the rat globus pallidus.
Journal: Journal of neurophysiology 20030301
Title: High frequency stimulation-induced dendritic calcium waves in rat hippocampal neurons.
Journal: Neuroscience letters 20021225
Title: Postnatal changes in the overall postsynaptic currents evoked in CA1 pyramidal neurons of the rat hippocampus.
Journal: Life sciences 20021220
Title: Intracellular QX-314 causes depression of membrane potential oscillations in lamprey spinal neurons during fictive locomotion.
Journal: Journal of neurophysiology 20020601
Title: Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats.
Journal: Anesthesiology 20020201
Title: Inhibition of wild-type and mutant neuronal nicotinic acetylcholine receptors by local anesthetics.
Journal: Molecular pharmacology 20011201
Title: Development of a behavioral model of TMJ pain in rats: the TMJ formalin test.
Journal: Pain 20011101
Title: Function of NMDA receptors and persistent sodium channels in a feedback pathway of the electrosensory system.
Journal: Journal of neurophysiology 20011001
Title: Voltage-gated sodium channels shape subthreshold EPSPs in layer 5 pyramidal neurons from rat prefrontal cortex.
Journal: Journal of neurophysiology 20011001
Title: Electrophysiology of interneurons in the glomerular layer of the rat olfactory bulb.
Journal: Journal of neurophysiology 20011001
Title: Ionic mechanisms underlying burst firing of layer III sensorimotor cortical neurons of the cat: an in vitro slice study.
Journal: Journal of neurophysiology 20010801
Title: Inhibition of m3 muscarinic acetylcholine receptors by local anaesthetics.
Journal: British journal of pharmacology 20010501
Title: Enhanced temporal stability of cholinergic hippocampal gamma oscillations following respiratory alkalosis in vitro.
Journal: Journal of neurophysiology 20010501
Title: Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics.
Journal: Molecular pharmacology 20010401
Title: Inhibition of the Na,K-ATPase of canine renal medulla by several local anesthetics.
Journal: Pharmacological research 20010401
Title: Ion selectivity filter regulates local anesthetic inhibition of G-protein-gated inwardly rectifying K+ channels.
Journal: Biophysical journal 20010201
Title: Local anesthetic inhibition of G protein-coupled receptor signaling by interference with Galpha(q) protein function.
Journal: Molecular pharmacology 20010201
Title: Gamma oscillation underlies hyperthermia-induced epileptiform-like spikes in immature rat hippocampal slices.
Journal: BMC neuroscience 20010101
Title: Molecular determinants of state-dependent block of Na+ channels by local anesthetics.
Journal: Science (New York, N.Y.) 19940916
Title: Block of deltamethrin-modified sodium current in cultured mouse neuroblastoma cells: local anesthetics as potential antidotes.
Journal: Brain research 19900604
