Name: Name:2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]aceticacid
Brand: AABLOCKS
SKU: AA01ENF7
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01ENF7

Chemical Name: 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]aceticacid

CAS Number: 1061605-21-7

Molecular Formula: C15H12N2O7

Molecular Weight: 332.2650

MDL Number: MFCD31560477

SMILES: OC(=O)COc1cccc2c1C(=O)N(C2=O)C1CCC(=O)NC1=O

Properties

Complexity: 617

Covalently-Bonded Unit Count: 1

Heavy Atom Count: 24

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 2

Rotatable Bond Count: 4

Undefined Atom Stereocenter Count: 1

XLogP3: -0.1

Downstream Synthesis Route

1061605-21-7

1799711-24-2

[1]CurrentPatentAssignee:UNIVERSITYOFMICHIGAN-WO2017/176958,2017,A1

[2]Zhou,Fei;Chen,Luyu;Cao,Chaoguo;Yu,Jiang;Luo,Xiaojiao;Zhou,Peiting;Zhao,Lifeng;Du,Wu;Cheng,Jijun;Xie,Yongmei;Chen,Yuanwei[EuropeanJournalofMedicinalChemistry,2020,vol.187]

[3]CurrentPatentAssignee:WISTARINSTITUTE;THOMASJEFFERSONUNIVERSITY-WO2020/92662,2020,A1

[4]Zhang,Jing;Fu,Liqiang;Shen,Bin;Liu,Yingtao;Wang,Wenqian;Cai,Xin;Kong,Linglong;Yan,Yilin;Meng,Ryan;Zhang,Zhuming;Chen,Ying-NanP.;Liu,Qian;Wan,Zhao-Kui;Zhou,Tianyuan;Wang,Xiaotao;Gavine,Paul;DelRosario,Amanda;Ahn,Kay;Philippar,Ulrike;Attar,Ricardo;Yang,Jennifer;Xu,Yanping;Edwards,JamesP.;Dai,Xuedong[CellChemicalBiology,2020,vol.27,#12,p.1500-13,1509]

1061605-21-7

1799711-21-9

[1]Papatzimas,JamesW.;Gorobets,Evgueni;Brownsey,DuncanK.;Maity,Ranjan;Bahlis,NizarJ.;Derksen,DarrenJ.[Synlett,2017,vol.28,#20,p.2881-2885]

[2]Papatzimas,JamesW.;Gorobets,Evgueni;Brownsey,DuncanK.;Maity,Ranjan;Bahlis,NizarJ.;Derksen,DarrenJ.[Synlett,2017,vol.28,#20,p.2881-2885]

[3]Bemis,TroyA.;LaClair,JamesJ.;Burkart,MichaelD.[ChemicalCommunications,2021,vol.57,#8,p.1026-1029]

[4]Hendrick,CharlesE.;Jorgensen,JeffR.;Chaudhry,Charu;Strambeanu,IuliaI.;Brazeau,Jean-Francois;Schiffer,Jamie;Shi,Zhicai;Venable,JenniferD.;Wolkenberg,ScottE.[ACSMedicinalChemistryLetters,2022,vol.13,#7,p.1182-1190]

1061605-21-7

CASUnavailable

1799711-21-9

[1]Xue,Gang;Wang,Kun;Zhou,Danli;Zhong,Hanbing;Pan,Zhengying[JournaloftheAmericanChemicalSociety,2019,vol.141,#46,p.18370-18374]

68076-36-8

1061605-21-7

1799711-24-2

[1]Yan,Guoyi;Zhong,Xinxin;Yue,Lin;Pu,Chunlan;Shan,Huifang;Lan,Suke;Zhou,Meng;Hou,Xueyan;Yang,Jie;Li,Rui[EuropeanJournalofMedicinalChemistry,2021,vol.212]

[2]CurrentPatentAssignee:UNIVERSITYOFMICHIGAN-WO2022/169834,2022,A2Locationinpatent:Page/Pagecolumn91;129

1061605-21-7 | 2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]aceticacid