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1799711-25-3,MFCD31560484
Catalog No.:AA01EO6T

1799711-25-3 | E3 ligase Ligand-Linker Conjugates 16

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100mg
95%
in stock  
$450.00   $315.00
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500mg
95%
in stock  
$1,736.00   $1,215.00
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1g
95%
in stock  
$3,215.00   $2,250.00
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2g
95%
in stock  
$4,500.00   $3,150.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA01EO6T
Chemical Name:
E3 ligase Ligand-Linker Conjugates 16
CAS Number:
1799711-25-3
Molecular Formula:
C21H23F3N4O8
Molecular Weight:
516.4245
MDL Number:
MFCD31560484
SMILES:
OC(=O)C(F)(F)F.NCCCCNC(=O)COc1cccc2c1C(=O)N(C2=O)C1CCC(=O)NC1=O
Properties
Computed Properties
 
Complexity:
780  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2017 Mar 24.

Title: James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.

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SDS
Tags:1799711-25-3 Molecular Formula|1799711-25-3 MDL|1799711-25-3 SMILES|1799711-25-3 E3 ligase Ligand-Linker Conjugates 16