+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 1807523-99-4
1807523-99-4,MFCD31746887
Catalog No.:AA01EO0D

1807523-99-4 | IACS-10759 Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$289.00   $202.00
- +
10mg
99%
1 week  
$400.00   $280.00
- +
25mg
99%
1 week  
$765.00   $535.00
- +
50mg
99%
1 week  
$1,082.00   $758.00
- +
100mg
99%
1 week  
$1,558.00   $1,091.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO0D
Chemical Name:
IACS-10759 Hydrochloride
CAS Number:
1807523-99-4
Molecular Formula:
C25H26ClF3N6O4S
Molecular Weight:
599.0249
MDL Number:
MFCD31746887
SMILES:
Cc1nc(nn1Cc1cccc(c1)N1CCC(CC1)S(=O)(=O)C)c1onc(n1)c1ccc(cc1)OC(F)(F)F.Cl
Properties
Computed Properties
 
Complexity:
909  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  

Literature

Title: Protopopova M. IACS-10759: A novel OXPHOS inhibitor which selectively kill tumors with metabolic vulnerabilities. [abstract In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 4380. doi:10.1158/1538-7445.AM2015-4380

Title: Jennifer R Molina, et al. An inhibitor of oxidative phosphorylation exploits cancer vulnerability. Nat Med. 2018 Jul;24(7):1036-1046.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1807523-99-4
1570496-34-2

1570496-34-2

 1570496-34-2

1570496-34-2
Building Blocks
More >
Tags:1807523-99-4 Molecular Formula|1807523-99-4 MDL|1807523-99-4 SMILES|1807523-99-4 IACS-10759 Hydrochloride