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Home Other Building Blocks 1985605-59-1
1985605-59-1,MFCD31619273
Catalog No.:AA01EOOI

1985605-59-1 | Baloxavir

Pack Size
Purity
Availability
Price(USD)
Quantity
  
50mg
≥98%
in stock  
$46.00   $32.00
- +
100mg
≥98%
in stock  
$88.00   $61.00
- +
250mg
97%
in stock  
$133.00   $93.00
- +
1g
95%
in stock  
$522.00   $365.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EOOI
Chemical Name:
Baloxavir
CAS Number:
1985605-59-1
Molecular Formula:
C24H19F2N3O4S
Molecular Weight:
483.4872
MDL Number:
MFCD31619273
SMILES:
Fc1c(F)ccc2c1CSc1c([C@H]2N2[C@@H]3COCCN3C(=O)c3n2ccc(=O)c3O)cccc1
Properties
Computed Properties
 
Complexity:
932  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
3.6  

Downstream Synthesis Route
40510-81-4   
baloxaviracid 
 
baloxavirmarboxil 

[1]Patent:JP5971830,2016,B1.Locationinpatent:Paragraph0080

[2]Patent:WO2020/58745,2020,A1.Locationinpatent:Page/Pagecolumn18

[3]Patent:JP6212678,2017,B1.Locationinpatent:Paragraph0058

[4]Patent:CN111233891,2020,A.Locationinpatent:Paragraph0076-0079

[5]Patent:JP6267397,2018,B1.Locationinpatent:Paragraph0089

[1]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP5971830,2016,B1Locationinpatent:Paragraph0080

[2]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP6267397,2018,B1Locationinpatent:Page/Pagecolumn0091

[3]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-WO2020/58745,2020,A1Locationinpatent:Page/Pagecolumn18;19

[4]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-US2020/261481,2020,A1Locationinpatent:Paragraph0281-0284

[1]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP5971830,2016,B1Locationinpatent:Paragraph0081

[2]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP6267397,2018,B1Locationinpatent:Paragraph0092

[3]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-US2020/261481,2020,A1Locationinpatent:Paragraph0285;0287-0288

[1]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP5971830,2016,B1Locationinpatent:Paragraph0081

[2]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP6267397,2018,B1Locationinpatent:Paragraph0094

[3]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-US2020/261481,2020,A1Locationinpatent:Paragraph0292-0293

[1]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP5971830,2016,B1Locationinpatent:Paragraph0082

[2]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-JP6267397,2018,B1Locationinpatent:Paragraph0096

[3]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-US2020/261481,2020,A1Locationinpatent:Paragraph0297-0299

Literature

Title: Omoto S, et al. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018 Jun 25;8(1):9633.

Title: Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Dec;160:109-117.

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SDS
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Tags:1985605-59-1 Molecular Formula|1985605-59-1 MDL|1985605-59-1 SMILES|1985605-59-1 Baloxavir