Home Other Building Blocks 1174428-47-7
1174428-47-7,MFCD31382129
Catalog No.:AA01EO2M

1174428-47-7 | SF2523

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$37.00   $26.00
- +
5mg
97%
in stock  
$92.00   $64.00
- +
10mg
97%
in stock  
$135.00   $95.00
- +
25mg
97%
in stock  
$230.00   $161.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EO2M
Chemical Name:
SF2523
CAS Number:
1174428-47-7
Molecular Formula:
C19H17NO5S
Molecular Weight:
371.4070
MDL Number:
MFCD31382129
SMILES:
O=c1cc(oc2c1scc2c1ccc2c(c1)OCCO2)N1CCOCC1
Properties
Computed Properties
 
Complexity:
578  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
2  
XLogP3:
2.9  

Downstream Synthesis Route
1174429-23-2   
2.3-dihydro-1,4-benzodioxin-6-ylboronicacid 
  1174428-47-7 

[1]JournalofMedicinalChemistry,2013,vol.56,p.1922-1939

[1]JournalofMedicinalChemistry,2013,vol.56,p.1922-1939

[1]JournalofMedicinalChemistry,2013,vol.56,p.1922-1939

[1]JournalofMedicinalChemistry,2013,vol.56,p.1922-1939

[1]JournalofMedicinalChemistry,2013,vol.56,p.1922-1939

Literature

Title: Carlino L, et al. Dual Kinase-Bromodomain Inhibitors in Anticancer Drug Discovery: A Structural andPharmacological Perspective. J Med Chem. 2016 Oct 27;59(20):9305-9320.

Title: Andrews FH, et al. Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1072-E1080.

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SDS
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