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Home Other Building Blocks 1442472-39-0
1442472-39-0,MFCD31657437
Catalog No.:AA01EO4S

1442472-39-0 | Ripretinib

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$116.00   $81.00
- +
10mg
≥95%
in stock  
$218.00   $152.00
- +
25mg
≥95%
in stock  
$426.00   $298.00
- +
50mg
≥95%
in stock  
$736.00   $515.00
- +
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA01EO4S
Chemical Name:
Ripretinib
CAS Number:
1442472-39-0
Molecular Formula:
C24H21BrFN5O2
Molecular Weight:
510.3582
MDL Number:
MFCD31657437
SMILES:
CNc1ncc2c(c1)n(CC)c(=O)c(c2)c1cc(NC(=O)Nc2ccccc2)c(cc1Br)F
Properties
Computed Properties
 
Complexity:
746  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
4.1  

Literature

Title: KIT/PDGFR Inhibitor DCC-2618.

Title: BLU-285, DCC-2618 Show Activity against GIST. Cancer Discov. 2017 Feb;7(2):121-122.

Title: Schneeweiss M, et al. The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis. Haematologica. 2018 May;103(5):799-809.

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