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Home Other Building Blocks 1948273-03-7
1948273-03-7,MFCD30729675
Catalog No.:AA01EO68

1948273-03-7 | E3 ligase Ligand 1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
10mg
98%
in stock  
$14.00   $10.00
- +
25mg
98%
in stock  
$18.00   $13.00
- +
50mg
98%
in stock  
$23.00   $16.00
- +
100mg
98%
in stock  
$23.00   $16.00
- +
250mg
98%
in stock  
$39.00   $27.00
- +
1g
98%
in stock  
$129.00   $90.00
- +
5g
98%
in stock  
$429.00   $300.00
- +
10g
98%
in stock  
$686.00   $480.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EO68
Chemical Name:
E3 ligase Ligand 1
CAS Number:
1948273-03-7
Molecular Formula:
C23H33ClN4O3S
Molecular Weight:
481.0511
MDL Number:
MFCD30729675
SMILES:
O[C@@H]1C[C@H](N(C1)C(=O)[C@H](C(C)(C)C)N)C(=O)N[C@H](c1ccc(cc1)c1scnc1C)C.Cl
Properties
Computed Properties
 
Complexity:
647  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:YALEUNIVERSITY;ARVINAS-WO2017/30814,2017,A1Locationinpatent:Paragraph00321

[1]CurrentPatentAssignee:STATEUNIVERSITYSYSTEMOFFLORIDA-WO2020/163823,2020,A2Locationinpatent:Page/Pagecolumn151-153

[1]CurrentPatentAssignee:STATEUNIVERSITYSYSTEMOFFLORIDA-WO2020/163823,2020,A2

Literature

Title: WO/2017/030814A1

Title: Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.

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SDS
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Tags:1948273-03-7 Molecular Formula|1948273-03-7 MDL|1948273-03-7 SMILES|1948273-03-7 E3 ligase Ligand 1