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Home Other Building Blocks 406228-55-5
406228-55-5,MFCD27665473
Catalog No.:AA01EONY

406228-55-5 | A-385358

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98% by HPLC
in stock  
$346.00   $242.00
- +
10mg
98% by HPLC
in stock  
$540.00   $378.00
- +
25mg
98% by HPLC
in stock  
$1,072.00   $751.00
- +
50mg
98% by HPLC
in stock  
$1,783.00   $1,248.00
- +
100mg
98% by HPLC
in stock  
$3,038.00   $2,127.00
- +
500mg
98% by HPLC
in stock  
$9,668.00   $6,768.00
- +
1000mg
98% by HPLC
in stock  
$15,433.00   $10,803.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EONY
Chemical Name:
A-385358
CAS Number:
406228-55-5
Molecular Formula:
C32H41N5O5S2
Molecular Weight:
639.8284
MDL Number:
MFCD27665473
SMILES:
CN(CC[C@@H](Nc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)(C)C)CSc1ccccc1)C
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
XLogP3:
7.2  

Literature

Title: Toward the development of innovative bifunctional agents to induce differentiation and to promote apoptosis in leukemia: clinical candidates and perspectives.

Journal: Journal of medicinal chemistry 20101014

Title: A small molecule-regulated guanine nucleotide exchange factor.

Journal: Journal of the American Chemical Society 20100127

Title: Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL.

Journal: Journal of medicinal chemistry 20070222

Title: A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo.

Journal: Cancer research 20060901

Title: Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo.

Journal: Journal of medicinal chemistry 20060209

Title: Shoemaker AR, et al. A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo. Cancer Res. 2006 Sep 1;66(17):8731-9.

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Tags:406228-55-5 Molecular Formula|406228-55-5 MDL|406228-55-5 SMILES|406228-55-5 A-385358