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13655-52-2,MFCD00242735
Catalog No.:AA01EOAX

13655-52-2 | Alprenolol

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25mg
≥98%
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$82.00   $57.00
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50mg
≥98%
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100mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOAX
Chemical Name:
Alprenolol
CAS Number:
13655-52-2
Molecular Formula:
C15H23NO2
Molecular Weight:
249.3486
MDL Number:
MFCD00242735
SMILES:
CC(C)NCC(COC1=CC=CC=C1CC=C)O
Properties
Computed Properties
 
Complexity:
231  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.1  

Literature

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Title: Simultaneous determination of three β-blockers at a carbon nanofiber paste electrode by capillary electrophoresis coupled with amperometric detection.

Journal: Talanta 20120815

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Title: Carvedilol blocks the cloned cardiac Kv1.5 channels in a β-adrenergic receptor-independent manner.

Journal: Biochemical pharmacology 20120215

Title: Gel formulations containing catanionic vesicles composed of alprenolol and SDS: effects of drug release and skin penetration on aggregate structure.

Journal: Colloids and surfaces. B, Biointerfaces 20120101

Title: Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study.

Journal: BMJ (Clinical research ed.) 20120101

Title: Impedance responses reveal β₂-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles.

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Journal: Journal of medicinal chemistry 20111013

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Title: Labeling of alprenolol with fluorescent aryl iodide as a reagent based on Mizoroki-Heck coupling reaction.

Journal: Journal of chromatography. A 20110520

Title: 1H and 13C NMR characteristics of β-blockers.

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Title: Involvement of β-adrenergic receptor in synaptic vesicle swelling and implication in neurotransmitter release.

Journal: Journal of cellular and molecular medicine 20110301

Title: Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.

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Title: Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis.

Journal: Biochemical pharmacology 20101115

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Journal: European journal of anaesthesiology 20100901

Title: Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography.

Journal: Journal of the American Chemical Society 20100825

Title: Noradrenergic modulation of behavioral odor detection and discrimination thresholds in the olfactory bulb.

Journal: The European journal of neuroscience 20100801

Title: Microcalorimetric and zeta potential study on binding of drugs on liposomes.

Journal: Colloids and surfaces. B, Biointerfaces 20100701

Title: Chiral separations of some beta-adrenergic agonists and antagonists on AmyCoat column by HPLC.

Journal: Chirality 20100101

Title: The importance of valine 114 in ligand binding in beta(2)-adrenergic receptor.

Journal: Protein science : a publication of the Protein Society 20100101

Title: Quantitative modeling of GRK-mediated beta2AR regulation.

Journal: PLoS computational biology 20100101

Title: Effect of radiation sterilization on alprenolol in the solid state studied by high-performance thin-layer chromatography.

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Title: Novel method of monitoring trace cytokines and activated STAT molecules in the paws of arthritic mice using multiplex bead technology.

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Title: A full pharmacological analysis of the three turkey β-adrenoceptors and comparison with the human β-adrenoceptors.

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Title: Comparison of the analysis of beta-blockers by different techniques.

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Title: Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer.

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Title: A new simple cell-based homogeneous time-resolved fluorescence QRET technique for receptor-ligand interaction screening.

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Title: Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.

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Title: Application of ionic liquids in high performance reversed-phase chromatography.

Journal: International journal of molecular sciences 20090601

Title: Modeling kinetics of subcellular disposition of chemicals.

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Title: Gel formation in systems composed of drug containing catanionic vesicles and oppositely charged hydrophobically modified polymer.

Journal: Colloids and surfaces. B, Biointerfaces 20090501

Title: Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.

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Title: Preparation and evaluation of propranolol molecularly imprinted solid-phase microextraction fiber for trace analysis of beta-blockers in urine and plasma samples.

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Title: Hydrophobicity-aided potentiometric detection of catecholamines, beta-agonists, and beta-blockers in a mixed-solvent capillary electrophoresis system.

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Title: Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of beta-Adrenergic Receptors to Phosphoinositide 3-Kinase.

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Title: Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.

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Title: Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines.

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Title: Enantioselective determination of alprenolol in human plasma by liquid chromatography with tandem mass spectrometry using cellobiohydrolase chiral stationary phases.

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Title: Enantiomeric separation by using nano-liquid chromatography with on-column focusing.

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Journal: Electrophoresis 20040401

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Journal: Electrophoresis 20030801

Title: Improvement of peak shape and separation performance of beta-blockers in conventional reversed-phase columns using solvent modifiers.

Journal: Journal of chromatographic science 20030801

Title: High-throughput screening to estimate single or multiple enzymes involved in drug metabolism: microtitre plate assay using a combination of recombinant CYP2D6 and human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030801

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Journal: The Journal of investigative dermatology 20030701

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Journal: Molecular pharmacology 20030601

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Journal: The Analyst 20030601

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Journal: British journal of pharmacology 20030401

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Journal: Assay and drug development technologies 20030401

Title: Chronic beta2-adrenergic receptor stimulation increases proliferation of human cardiac fibroblasts via an autocrine mechanism.

Journal: Cardiovascular research 20030301

Title: Evidence against beta 3-adrenoceptors or low affinity state of beta 1-adrenoceptors mediating relaxation in rat isolated aorta.

Journal: British journal of pharmacology 20030101

Title: Chronic infusion of beta-adrenoceptor antagonist and inverse agonists decreases elevated protein kinase A activity in transgenic mice with cardiac-specific overexpression of human beta 2-adrenoceptor.

Journal: Journal of cardiovascular pharmacology 20020901

Title: Integrated acquisition of analytical and biopharmaceutical screening data for beta-adrenergic-drugs employing diversified macrocycle supported potentiometric detection in HPLC systems.

Journal: Current medicinal chemistry 20020801

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Journal: Chirality 20020701

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Journal: The Journal of biological chemistry 20020419

Title: Responsiveness, affinity constants and beta-adrenoceptor reserves for isoprenaline on aortae from normo-, pre- and hypertensive rats.

Journal: The Journal of pharmacy and pharmacology 20020401

Title: Controlled drug release from gels using lipophilic interactions of charged substances with surfactants and polymers.

Journal: Journal of colloid and interface science 20020401

Title: Cationic amphiphilic drugs and platelet phospholipase A(2) (cPLA(2)).

Journal: Thrombosis research 20020215

Title: Screening drugs for metabolic stability using pulsed ultrafiltration mass spectrometry.

Journal: Combinatorial chemistry & high throughput screening 20020201

Title: Interface for coupling nonaqueous wide-bore capillary electrophoresis with mass spectrometry.

Journal: Electrophoresis 20020201

Title: Comparison of the affinity of beta-blockers for two states of the beta 1-adrenoceptor in ferret ventricular myocardium.

Journal: British journal of pharmacology 20020101

Title: p38 MAPK activation triggers pharmacologically-induced beta-adrenergic preconditioning, but not ischaemic preconditioning.

Journal: Journal of molecular and cellular cardiology 20011201

Title: Controlled drug release from gels using surfactant aggregates. II. Vesicles formed from mixtures of amphiphilic drugs and oppositely charged surfactants.

Journal: Pharmaceutical research 20011101

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Journal: Electrophoresis 20011001

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Journal: Journal of medicinal chemistry 20010719

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Journal: Journal of medicinal chemistry 20010607

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Journal: Journal of chromatography. A 20010406

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Journal: European journal of pharmacology 20010323

Title: High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.

Journal: Journal of medicinal chemistry 20010315

Title: Characterization of [3H]CGP 12177 binding to beta-adrenergic receptors in intact eel hepatocytes.

Journal: General and comparative endocrinology 20010301

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Journal: AAPS pharmSci 20010301

Title: Influence of the solute hydrophobicity on the enantioselective adsorption of beta-blockers on a cellulase protein used as the chiral selector.

Journal: Journal of chromatography. A 20010105

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Journal: The Journal of endocrinology 20010101

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Tags:13655-52-2 Molecular Formula|13655-52-2 MDL|13655-52-2 SMILES|13655-52-2 Alprenolol